A COF Syrup100 ml.
A COF 100 ml.CompositionEach 5 ml contains Dextromethorphan Hydrobromide BP 20 mg, Phenylephrine Hydrochloride BP 10 mg and Triprolidine Hydrochloride BP 2.5 mg.PHARMACOLOGYDextromethorphan Hydrobromide is a cough suppressant used to treat coughing. Phenylephrine Hydrochloride stimulates postsynaptic alpha-receptors, resulting in vasoconstriction, which reduces nasal congestion. Triprolidine Hydrochloride is a sedating antihistamine which is used for the symptomatic relief from allergic rhinitis.IndicationsTemporarily relieves these symptoms due to common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:• cough due to minor throat of bronchial irritation• runny nose• sneezing• itching of the nose or throat• itchy, watery eyes• nasal congestion• reduces swelling of nasal passagesDose and AdministrationRoute of Administration : Oral. Adults & Children 12 years of age and older : 1 teaspoonful (5 ml) every 4 hours. Children 6 to under 12 years age : ½ teaspoonful (2.5 ml) every 4 hours. Or as directed by the physician. Contraindications• Patients with hypersensitivity to Dextromethorphan Hydrobromide, PhenylephrineHydrochloride and Triprolidine Hydrochloride.• Persons under treatment with Monoamine Oxidase Inhibitor (MAO) within 2 weeks of stopping such treatment.Precaution and WarningAs with other sympathomimetic agents, caution should be exercised in patients with hypertension, heart disease, diabetes, thyroid disease or glaucoma. This combination should not be used for persistent or chronic cough which occurs with smoking, asthma, chronic bronchitis or for a couth with excessive secretion of phlegm unless directed by a physician. Precaution should be taken for persons with trouble urinating due to an enlarged prostate gland. This combination may impair the patients ability to drive and also to operate machinery.Side EffectsCommon Side Effects : It may cause drowsiness, dottiness and constipation. Other side effects that may occur include GIT discomfort. Rare Side Effects : Other less common side effects may include transient hypertension, dry mouth, restlessness, palpitations, allergic reactions such as rashes, tightness of chest, thickening of bronchial secretions, toxic psychosis and blood dyscrasia. Use in Pregnancy & Lactation There are no specific data on use of this combination during pregnancy and lactation. Use in children & adolescents Not to be used in children below 2 years old. To be used with caution, and as advised by the physician for children age 2 to 6 years.Drug InteractionWith medicine : Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Caution should be excercised while taking this drug with antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (e.g. atropine, belladonna alkaloids), beta blockers (e.g. metoprolol, atenolol), drugs for Parkinson’s disease (e.g. anticholinergics such as benztropine, trihexyphenidyl), guanethidine, certain inhaled anesthetics (e.g. halothane), methyldopa, reserpine, scopolamine, tricyclic antidepressants (e.g. amitriptyline, desipramine), anti-seizure drugs (e.g. carbamazepine), medicine for sleep or anxiety (e.g. alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g. codeine), psychiatric medicines (e.g. chlorpromazine, risperidone, amitriptyline, trazodone). With food and others : There is no data found on interaction with food of this medicine.Over dosageIn cases of over dosage, hospital admission is strongly advised. Over dosage may produce respiratory depression, paranoid psychosis, delusions, hallucinations, and convulsion. Treatment should include emptying the stomach by aspiration or gastric lavage. Nervous stimulation and convulsions should be treated with a sedative such as diazepam intramuscularly. If marked excitation is present, a sedative such as diazepam or a short-acting barbiturate may be given. Severe over dosage of phenylephrine hydrochloride may produce hypertension and associated reflex bradycardia. Treatment measures include early gastric lavage and symptomatic and supportive measures. The hypertensive effects may be treated with an alpha receptor blocking agent (such as phentolamine mesilate 6-10 mg) given intravenously, and the bradycardia treated with atropine, preferable only after the pressure has been controlled.StorageKeep all medicines out of reach of children. Store below 300 C., Protect from light.PackingEach bottle contains 100 ml syrup. ..
Tk.100.00/=
A Phenicol 10 ml Eye Drops
A PhenicolDESCRIPTIONChloramphenicol is a broad spectrum antibiotic, isolated in 1947 from streptomyces venezuelae. It is primarily bacteriostatic and acts by inhibition of protein synthesis. It has been noted that chloramphenicol is found in measurable amounts in the aqueous humor following local application to the eye. Development of resistance to Chloramphenicol is minimum for staphylococci and many other species of bacteria.COMPOSITIONEYE OINTMENT : Each gm contains 10 mg of Chloramphenicol BP in a special base. It is a sterile eye ointment.EYE/EAR DROPS : Each ml eye/ear drops contains Chloramphenicol BP 5 mg. It is a sterile eye / ear drops.INDICATIONSA-PHENICOL is indicated in surface ocular infections involving the conjunctiva and/or cornea caused by Chloramphenicol susceptible organisms. A-PHENICOL is also active against common bacterial pathogens, E.coli, Klebsiella, Niesseria sp., H.influenzae, Enterobacter sp., Staphylococcus aureus and Streptococcus pneumoniae.A-PHENICOL is also indicated in ear canal infection.DOSAGE AND ADMINISTRATIONA-PHENICOL Eye OintmentA PHENICOL eye ointment should be used every three hours. Administration should be continued day and night for the first 48 hours after which the interval between application may be increased and continued for at least 2 days after the eye appears normal.A-PHENICOL Eye/Ear DropsFor eye : 2 drops of solution every 1 hour, until condition improves or instill 4 times daily depending on severity of infection. For ear : (Adult & Children) : 2 or 3 drops in the affected ear 2-3 times daily. OR AS DIRECTED BY THE PHYSICIAN.CONTRAINDICATIONSChloramphenicol is contraindicated in patients sensitive to any of its components.PRECAUTIONSOphthalmic ointments may retard corneal wound healing. So patients with corneal disease should take precautions while using this medicine.SUPPLYA-PHENICOL Eye Ointment : A-PHENICOL Eye Ointment is supplied in 5 gmcollapsible tube.A-PHENICOL Eye/Ear Drops : A-PHENICOL Eye/Ear Drops is supplied in 10 mlplastic bottle with dropper...
Tk.34.50/=
A Spasm 5 mg Tablet
A Spasm 5 mg TabletIndicationsAbdominal pain, Colic, Gastrointestinal tract spasm, Peptic ulcer disease, Visceral spasmsPharmacologyOxyphenonium is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Oxyphenonium is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Oxyphenonium inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions.ContraindicationsUrinary outflow obstruction, paralytic ileus, myasthenia gravis.Side EffectsDryness of mouth, difficulty in talking/swallowing; reduced bronchial secretions; blurring of vision, photophobia; bradycardia followed by tachycardia and arrhythmias; urinary retention, constipation, vomiting, nausea; confusion and giddiness...
Tk.1.50/=
A Tetra 1% 5 gm Ointment
A Tetra 1%DESCRIPTIONA-TETRA (Tetracycline) is a semi-synthetic Tetracycline produced from Chlortetracycline. It is an antibiotic isolated from Streptomyces aureo-faciens. It is a broad spectrum antibiotic which is active against a wide range of Gram-negative and Gram-positive bacteria. Tetracycline has its main mechanism of action on protein synthesis, and an energy-dependent active transport system pumps the drug through the inner cytoplasmic membrane of the bacteria. Once inside the bacterial cell, Tetracycline inhibits protein synthesis by binding specifically to 30S ribosome. The drug appears to prevent access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. This prevents the addition of amino acid to the growing peptide chain.COMPOSITIONCapsule : Each capsule contains Tetracycline Hydrochloride BP 500 mg.Tablet : Each tablet contains Tetracycline Hydrochloride BP 500 mg.INDICATIONSA-TETRA is a bacteriostatic antibiotic with a broad spectrum of activity against bacteria, and also has some anti-protozoal activities. It remains the choice in the treatment of Chlamydia, Rickettsia, Mycoplasma, Brucella and some Spirochaetal infections. A number of Gram-negative and Grampositive pathogens can be treated with Tetracycline. It has been given long term in the management of severe acne.When Penicillin is contraindicated, the Tetracyclines are alternative drugs in the treatment of infection.DOSAGE AND ADMINISTRATIONCapsule : The usual dose is 1 to 2 g/day (2-4 capsules) divided in 2 or 4 equal doses depending on the severity of the infection, preferably one hour before or two hours after meals with a glass of water.Tablet : 1-1/2 tablet (250-500 mg) should be taken after 6 hours. Preferably one hour before or two hours after meal with a glass of water.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSCommon side effects are gastro-intestinal disturbances including nausea, vomiting and diarrhoea. These are common especially with high doses and most are attributed to irritation of the mucosa. Other effects that have been reported are dry mouth, glossitis and discoloration of the tongue,stomatitis and dyspepsia. Benign intracranial hypertension, pancreatitis and pseudomembranous colitis are reported.CONTRAINDICATIONSTetracycline is contraindicated in patients hypersensitive to any of its group. It should be avoided in patients with systemic lupus erythematosus. It is also contraindicated in severe renal impairment, if given, doses should be reduced.PRECAUTIONSCare should be taken if Tetracycline is given to patients with impaired liver function.Potential hepatotoxic drugs including Erythromycin, Chloram-phenicol, Isoniazid, Sulfonamide etc. should not be given concomitantly. The risk of nephrotoxicity may be increased if given with Methoxyflurane or other potentially nephrotoxic medication. Care is advisable in patients with Myasthenia gravis, who may be at risk of neuromuscular blockade.WARNINGSThe use of Tetracycline hydrochloride during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of the teeth.DRUG INTERACTIONSIt has been reported that Tetracycline in combination with Methoxyflurane have resulted in nephrotoxicity. Milk and milk products as well as antacids containing calcium, aluminium and magnesium impair the absorption of Tetracycline and resulting decreased serum levels. Tetracycline inhibits the antimicrobial activity of penicillin when used concomitantly...
Tk.12.00/=
A-B1 100 mg Tablet, 1 strip
A-B1 100 mg Tablet, 1 stripDESCRIPTIONA-B1 (Thiamine Hydrochloride) is a water soluble vitamin. It is an organicmolecule which contains a pyrimidine and a thiazole nucleus linked by amethylene bridge. It occurs as small white hygroscopic crystals orcrystalline powder that usually has a slight characteristic odour. Itfunctions in the body in the form of coenzyme Thiamine pyrophosphate.Thiamine pyrophos-phate serves as a coenzyme in carbohydratemetabolism by decar-boxylation of a-keto acids such as pyruvate anda-ketoglutarate which leads to the formation of acetyl CoA. Thiamine orVitamin B1 also participates in the formation or degradation of a-ketols bytransketolase. Vitamin B1 is essential for metabolism of carbohydrate.Recommended daily intake of Thiamine is 0.5mg/1000 kcal. Majorsymptoms of Thiamine deficiency are related to the nervous system (Dryberiberi) and to the cardiovascular system (Wet beriberi).COMPOSITIONEach tablet contains Thiamine Hydrochloride BP 100 mg.INDICATIONSInfantile beriberi : Loss of appetite, vomiting, greenish stools, followed byparoxysmal attacks of muscular rigidity.Adult beriberi : Dry skin, discomfort, confabulation followed by paralysis.Wernicke's encephalopathy : Neuropsychiatric disorder may develop insome cases due to alcohol intake.Korsakoff's syndrome : Diabetes, cancer and in other cases for examplethe patients having nutritional intake parenterally where Vitamin B1 isabsent may arise Vitamin B1 deficiency.Fatigue, anorexiaGastrointestinal disturbanceNeurological disorderOther Vitamin B1 deficiency in case of pregnancy and lactation.DOSAGE AND ADMINISTRATIONMild to moderate chronic deficiency : ¼ tablet daily.Severe deficiency : 2-3 tablets daily.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSNo known side effect have yet been established.CONTRAINDICATIONSA-B1 is contraindicated in patients who are hypersensitive to it.SUPPLYEach box contains 10 x 10 tablets in blister strip...
Tk.8.60/=
A-Cal 500 mg Tab
A-Cal 500 mg TabDESCRIPTIONCalcium is an essential body electrolyte. It is involved in the maintenance of normal muscle and nerve function, cardiac function and is essential to blood coagulation.Calcium Carbonate has three main actions: it supplements dietary calcium, neutralizes gastric acid in peptic ulcer disease and sequesters phosphorous in the intestine to reduce total body phosphate accumulation in chronic renal failure. Calcium requirement varies with age and is relatively greater in childhood, pregnancy and lactation dueto an increased demand, in old age due to impaired absorption, and as phosphate binder in patients with renal failure. Absorption depends on previous intake of calcium, other nutrients, pregnancy, lactation, overall calcium balance and availability of vitamin D.COMPOSITIONA-CAL 250 chewable : Each chewable tablet contains Calcium Carbonate BP 0.625 g equivalent to 250 mg elemental Calcium. A-CAL 250 : Each film-coated tablet contains Calcium Carbonate BP 0.625 g equivalent to 250 mg elemental Calcium. A-CAL 500 : Each film-coated tablet contains Calcium Carbonate BP 1.25 g equivalent to 500 mg elemental Calcium.INDICATIONSIn calcium deficiency states : Treatment of calcium deficiency states including osteomalacia, rickets and mal-absorption syndromes affecting the upper gastrointestinal tract.As therapeutic supplementation : During times when intake may be inadequate, particularly those associated with the increased demand of childhood, old age, pregnancy and lactation. As a phosphate binder : As effective phosphate binder given by mouth to reduce phosphate absorption from the gut in patient with hyperphosphataemia, chronic renal failure in order to prevent the development of renal osteo-dystrophy. Osteoporosis : An adjunct to conventional therapy in the arrest or slowing down of bone demineralisation in osteoporosis or when other effective treatment is contraindicated. As an antacid : Usually in association with other antacids, especially magnesium containing antacids.DOSAGE AND ADMINISTRATIONA-Cal 250 :Adults : 2 tablets daily.Children : 1-2 tablets daily.A-Cal 500 : 1 tablet daily.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSMild gastrointestinal disturbances may occur rarely (e.g. nausea, abdominal pain, constipation, flatulence and eructation etc.)CONTRAINDICATIONSCalcium Carbonate is contraindicated in hypercalcemia and hyperparathyroidism, hypercalcemia and nephrolithiasis, Zollinger Ellison Syndrome etc.PRECAUTIONSShould be used with caution in patients with impaired renal function, a history of stone formation should also be recommended to increase their fluid intake. High doses of vitamin D should be avoided during calcium therapy unless specially indicated. In case of hypercalciuria the dosage should be reduced or treatment stopped.USE IN PREGNANCY AND LACTATIONCalcium supplements have been in wide use for many years without apparent ill consequence.DRUG INTERACTIONSCalcium Carbonate and other antacids may interfere with the absorption of concomitantly administered tetracycline preparations or ciprofloxacin. This can be minimized by giving Calcium Carbonate and the other medication 2 to 3 hours apart.SUPPLYA-CAL 250 chewable : Each box contains 3 X 10 tablets in blisterstrips.A-CAL 250 : Each box contains 10 X 10 tablets in blister strips.A-CAL 500 : Each box contains 10 X 10 tablets in blister strips...
Tk.5.00/=
A-Cal 500/400 IU Tablet DX 30's pack
A-Cal 500/400 IU Tablet DX 30's packDESCRIPTIONA-Cal DX tablet is a special preparation of Calcium and Vitamin D3. Calcium is an essential nutrient that helps to build and maintain healthy teeth and bones. It makes body’s framework stronger by building bone.COMPOSITIONEach film-coated tablet contains Calcium Carbonate BP equivalent to elemental Calcium 500 mg and Vitamin D3 (Cholecalciferol) BP 400 IU.INDICATIONFor the prevention and/or treatment of osteoporosis,fractures,osteomalacia,rickets,tetany,pse udo-parathyroidism, for healthy bone formation and maintenance and other calcium and/or vitamin D deficiencies and to meet increased needs of calcium and/or vitamin D. Dosage and Administration: The recommended starting dose of A-Cal DX (Calcium 500 mg & Vitamin D 400 IU) 1 tablet twice daily, preferably with or just after meals.SIDE EFFECTSThe use of calcium supplements may cause constipation, and headache; mild hypercalcemia associated with anorexia, nausea and vomiting; more severe hypercalcemia associated with confusion, delirium, stupor and coma. The use of vitamin D may cause weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain, metallic taste, polyuria, polydipsia, anorexia, weight loss, nocturia and mild acidosis. CONTRAINDICATION A-Cal DX is contraindicated in patients Having hyperalcaemia, severe hypercalciurea, ventricular fibrillation, hypervitaminosis, severe renal failure and kidney stones and hypersensitivity to any of the ingredients of the product.PRECAUTIONPatients with mild to moderate renal failure or mild hypercalciuria should be supervised carefully. Periodic checks of plasma calcium levels and urinary calcium excretion should be made in patient with a history of renal stones or in patients with mild to moderate renal failure or mild hypercalciuria. USE IN PREGNANCY AND LACTATION A-Cal DX should be used under the direction of a physician during pregnancy and lactation. During pregnancy, doses of vitamin D greater than the recommended dietary allowance should be used only when clearly needed.DRUG INTERACTIONCo-administration of calcium with some drugs such as tetracycline antibiotics (e.g., doxycycline, minocycline), estramustine, levothyroxine, and quinolone antibiotics (e.g. ciprofloxacin, levofloxacin) can decrease the absorption of both calcium and the co-administered drug. Certain medications can decrease the absorption of vitamin D e.g., bile acid sequestrates such as cholestyramine/colestipol, ketoconazole, mineral oil, orlistat. Certain drugs can accelerate the absorption of vitamin D e.g. phenytonin, phenobarbital.SUPPLYEach plastic container contains 30 tablets...
Tk.225.00/=
A-Cal D 30s Tab
A-Cal D 30s TabDESCRIPTIONA-CAL D tablet is a special preparation of Calcium and Vitamin D3. Calcium is an essential nutrient that helps to build and maintain healthy teeth and bones. It makes body's framework stronger by building bone. Most notably, Calcium helps to reduce the risk of osteoporosis, a disease that's characterized by a decrease in bone mass and an increase in bone fractures. Calcium also plays a role in muscle contraction, blood clotting and nerve function.Vitamin D3 is essential for healthy bones as it aids in calcium absorption from the GI tract. In addition to this it stimulates bone formation. Controlled clinical studies showed that Calcium and Vitamin D3 has synergistic effects on bone growth as well as in osteoporosis and fracture prevention.COMPOSITIONEach film-coated tablet contains elemental Calcium 500 mg and Vitamin D3 200 IU.INDICATIONSPrevention and treatment of osteoporosis and fractures (both vertebral and non-vertebral); treatment of osteomalacia, rickets, tetany, hypoparathyroidism and secondary hyperparathyroidism; in kidney disease, pancreatitis, hyperoxaluria; as phosphate binder to reduce phosphate absorption in patients with hyperphosphatemia; during therapy with antiseizure medications, bisphosphonates in paget's disease; for healthy bone formation and maintenance; in disorders of osteogenesis and tooth formation (in addition to specific treatment); inpregnancy and lactation due to increased demand; in raised calcium requirement for children and adolescents at times of rapid growth; to prevent and cure calcium deficiency and/or vitamin D deficiency especially in the household people who do not get direct sunlight. DOSAGE AND ADMINISTRATION Adults, Elderly and children: 1 tablet twice daily. OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSThe use of calcium supplements may cause constipation, and headache; mild hypercalcemia associated with anorexia, nausea and vomiting; more severe hypercalcemia associated with confusion, delirium, stupor and coma. The use of vitamin D may cause weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain, metallic taste, polyuria, polydipsia, anorexia, weight loss, nocturia and mild acidosis.PRECAUTIONSPatients with mild to moderate renal failure or mild hypercalciuria should be supervised carefully. Periodic checks of plasma calcium levels and urinary calcium excretion should be made in patients with a history of renal stones or in patients with mild to moderate renal failure or mild hypercalciuria. With long term treatment it is advisable to monitor serum and urinary calcium levels and kidney function and reduce or stop treatment temporarily if serum calcium level exceeds 12 mg/dl. Calcium salt should be used cautiously in patients with sarcoidosis, history of nephrolithiasis, cardiac disease and in patients receiving cardiac glycosides.CONTRAINDICATIONSIt is contraindicated in patients having hypercalcaemia and severe hypercalciurea, ventricular fibrillation, hypervitaminosis, severe renal failure, kidney stones and hypersensitivity to any of the ingredients of the product.DRUG INTERACTIONA-CAL D should not be used with the following medications because ofpossible interactions - Iron; digoxin; verapamil; calcium, aluminium or magnesium containing antacids; other calcium or vitamin D supplements (e.g., calcitriol). Bran decreases the gastrointestinal absorption of calcium and may therefore decrease the efficacy of calcium supplements. Concurrent administration of thiazide diuretics may increase the risk of hypercalcemia. Co-administration of calcium with some drugs such as tetracycline antibiotics (e.g., doxycycline, minocycline), estramustine, levothyroxine, and quinolone antibiotics (e.g., ciprofloxacin, levofloxacin) can decrease the absorption of both calcium and the co-administered drug. Certain medications can decrease the absorption of vitamin D e.g., bile acid sequestrates such as cholestyramine/ colestipol, ketoconazole, mineral oil, orlistat. Certain drugs can accelerate the absorption of vitamin D e.g., phenytoin, phenobarbital.OVER DOSAGEIf calcium supplements are taken at overdose for long time then hypercalcimia and hypercalciuria may rise. Symptoms of overdosage of vitamin D supplements include weakness, lassitude, impaired memory, dementia, depression, paranoia, hallucinations, delirium and coma. In case of overdose supplement should be discontinued. Treatment includes saline administration, furosemide diuresis and sometimes corticosteroids.USE IN PREGNANCY AND LACTATIONA-CAL D should be used under the direction of a physician during pregnancy and lactation. Vitamin D and its metabolites pass into the breast milk in limited amounts.SUPPLY30 Tablet Pack : Each airtight plastic container contains 30 tablets.15 Tablet Pack : Each airtight plastic container contains 15 tablets...
Tk.195.00/=
A-CALM 50 mg Tablet
A-CALM 50 mg TabletDESCRIPTIONTolperisone hydrochloride is a centrally acting muscle relaxant, which acts on the central nervous system and used mainly for the treatment of elevated muscle tone and tension as well as for certain circulatory problems in the extremities. It reduces experimental hypertonia and decerebration and improves peripheral blood flow. The circulatory effect is supposed to be based on peripheral mechanism and is independent from the cerebral centers of vasoregulation.COMPOSITIONEach film-coated tablet contains Tolperisone hydrochloride INN 50 mg.INDICATIONSIncreased tone of skeletal muscles due to organic neurological disorders (e.g. injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis etc.), muscular hypertension, muscular spasm, muscular contraction & rigidity, spinal automatism and discopathy. Obliterate vascular diseases (obliterate arteriosclerosis, diabetic angiopathy, obliterative thromboangitis, raynaud's disease, diffusion scleroderma) and disorders due to injury innervation of the vessels (acrocyanosis, intermittent angioneurotic dysbasia). In individual cases post thrombotic venous and circulation disorders and crural ulcer.DOSAGE AND ADMINISTRATIONOne should follow the doctor's instructions regarding the dosage of Tolperisone hydrochloride. The recommended dose is as followings: Adult: 50-150 mg three times daily according to the individual requirement and tolerance of the patients. Children: (from 6 to 14 years): 2-4 mg/kg/day in three divided doses. Children: (from 3 months to 6 years): 5-10 mg/kg/day in three divided doses.SIDE EFFECTSSometimes muscular weakness, headache, nausea, vomiting, and rarely hypersensitivity reactions.CONTRAINDICATIONSHypersensitivity to Tolperisone, Myasthenia gravis, nursing mother. PRECAUTIONS Incase of children, the prescribed dose and duration of treatment should closely be observed.USE IN PREGNANCY AND LACTATIONTolperisone hydrochloride should be used in pregnancy to physician's advice. Tolperisone hydrochloride should not be used during breastfeeding.DRUG INTERACTIONConcomitant use of methocarbamol with tolperisone hydrochloride has been reported to cause disturbance of visual accommodation.SUPPLYEach box contains 5 x 10 tablets in blister strips..
Tk.6.00/=
A-clox 500 mg cap
A-clox 500 mg capDESCRIPTIONA-CLOX is a bactericidal antibiotic that is particularly useful against penicillinase producing Staphylococci. It is a semisynthetic member of the penicillin family. It kills bacteria by interfering the synthesis of the bacterial cell wall. A-CLOX is widely used against Gram-positive bacteria.COMPOSITIONA-CLOX capsule : Each capsule contains Cloxacillin Sodium BP equivalent to Cloxacillin 500 mg.A-CLOX Powder for Syrup : Each 5 ml contains Cloxacillin Sodium BP equivalent to 125 mg Cloxacillin after reconstitution.A-CLOX 250 mg Injection : Each vial contains sterile Cloxacillin Sodium BP equivalent to 250 mg Cloxacillin.A-CLOX 500 mg Injection : Each vial contains sterile Cloxacillin Sodium BP equivalent to 500 mg Cloxacillin.INDICATIONS Respiratory tract infection : Bronchitis Bronchiectasis, otitis media, sinusitis, pneumonia, tonsillitis, pharyngitis. Skin and soft tissue infections : Cellulitis, styes, furuncles, pemphigus, breast abscess, carbuncles, infected burns. Other infections : Osteomyelitis, acute and subacute endocarditis, urinary tract infections, obstetric infections, prophylaxis in neonatal infections.DOSAGE AND ADMINISTRATIONAdults : Oral : 500 mg six hourly ½ -1 hour before meals Intramuscular injection : 250 mg every 4-6 hours. Intravenous injection : 500 mg every 4-6 hours. In serious infections dosage may be doubled. Children (2-10 years) : 1-2 tea spoonful 6 hourly or ½ of the adult dose. Upto 2 years : ¼ of the adult dose.OR AS DIRECTED BY THE PHYSICIANInjection AdministrationFor Intramuscular injection : 250 mg and 500 mg are to be dissolved with 1.5 ml and 2 ml water for injection BP respectively before administration. For Intravenous injection : 500 mg is to be dissolved with 5-8 ml water for injection BP administered by slow injection for 3 to 4 minutes. Adequately diluted A-CLOX injection can be administered into the drip tube slowly over a period of 3 to 4 minutes.CONTRAINDICATIONSCloxacillin is contraindicated to Penicillin hypersensitive patients.SIDE EFFECTOccasional rashes, nausea, diarrhoea or indigestion may rarely be reported.SUPPLYCapsule : Box containing 1010 capsules in stripsPowder for Syrup : Bottle containing required amount of powder toprepare 100 ml syrup.A-CLOX 250 mg injection : Box contains 5 blister packs each containingone vial and one 5 ml ampoule of water for injection.A-CLOX 500 mg injection : Box contains 5 blister packs each containingone vial and one 5 ml ampoule of water for injection...
Tk.5.98/=
A-Cof 100ml Syp
A-Cof 100ml SypCompositionEach 5 ml contains Dextromethorphan Hydrobromide BP 20 mg, Phenylephrine Hydrochloride BP 10 mg and Triprolidine Hydrochloride BP 2.5 mg.PHARMACOLOGYDextromethorphan Hydrobromide is a cough suppressant used to treat coughing. Phenylephrine Hydrochloride stimulates postsynaptic alpha-receptors, resulting in vasoconstriction, which reduces nasal congestion. Triprolidine Hydrochloride is a sedating antihistamine which is used for the symptomatic relief from allergic rhinitis.IndicationsTemporarily relieves these symptoms due to common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:• cough due to minor throat of bronchial irritation• runny nose• sneezing• itching of the nose or throat• itchy, watery eyes• nasal congestion• reduces swelling of nasal passagesDose and Administration Route of Administration : Oral. Adults & Children 12 years of age and older : 1 teaspoonful (5 ml) every 4 hours. Children 6 to under 12 years age : ½ teaspoonful (2.5 ml) every 4 hours. Or as directed by the physician. Contraindications• Patients with hypersensitivity to Dextromethorphan Hydrobromide, PhenylephrineHydrochloride and Triprolidine Hydrochloride.• Persons under treatment with Monoamine Oxidase Inhibitor (MAO) within 2 weeks of stopping such treatment.Precaution and WarningAs with other sympathomimetic agents, caution should be exercised in patients with hypertension, heart disease, diabetes, thyroid disease or glaucoma. This combination should not be used for persistent or chronic cough which occurs with smoking, asthma, chronic bronchitis or for a couth with excessive secretion of phlegm unless directed by a physician. Precaution should be taken for persons with trouble urinating due to an enlarged prostate gland. This combination may impair the patients ability to drive and also to operate machinery.Side EffectsCommon Side Effects : It may cause drowsiness, dottiness and constipation. Other side effects that may occur include GIT discomfort. Rare Side Effects : Other less common side effects may include transient hypertension, dry mouth, restlessness, palpitations, allergic reactions such as rashes, tightness of chest, thickening of bronchial secretions, toxic psychosis and blood dyscrasia. Use in Pregnancy & Lactation There are no specific data on use of this combination during pregnancy and lactation. Use in children & adolescents Not to be used in children below 2 years old. To be used with caution, and as advised by the physician for children age 2 to 6 years.Drug InteractionWith medicine : Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Caution should be excercised while taking this drug with antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (e.g. atropine, belladonna alkaloids), beta blockers (e.g. metoprolol, atenolol), drugs for Parkinson’s disease (e.g. anticholinergics such as benztropine, trihexyphenidyl), guanethidine, certain inhaled anesthetics (e.g. halothane), methyldopa, reserpine, scopolamine, tricyclic antidepressants (e.g. amitriptyline, desipramine), anti-seizure drugs (e.g. carbamazepine), medicine for sleep or anxiety (e.g. alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g. codeine), psychiatric medicines (e.g. chlorpromazine, risperidone, amitriptyline, trazodone). With food and others : There is no data found on interaction with food of this medicine.Over dosageIn cases of over dosage, hospital admission is strongly advised. Over dosage may produce respiratory depression, paranoid psychosis, delusions, hallucinations, and convulsion. Treatment should include emptying the stomach by aspiration or gastric lavage. Nervous stimulation and convulsions should be treated with a sedative such as diazepam intramuscularly. If marked excitation is present, a sedative such as diazepam or a short-acting barbiturate may be given. Severe over dosage of phenylephrine hydrochloride may produce hypertension and associated reflex bradycardia. Treatment measures include early gastric lavage and symptomatic and supportive measures. The hypertensive effects may be treated with an alpha receptor blocking agent (such as phentolamine mesilate 6-10 mg) given intravenously, and the bradycardia treated with atropine, preferable only after the pressure has been controlled.StorageKeep all medicines out of reach of children. Store below 300 C., Protect from light.PackingEach bottle contains 100 ml syrup. ..
Tk.100.00/=
A-Cold 100ml Syp
A-Cold 100ml SypDESCRIPTIONA-Cold (Bromhexine Hydrochloride) is a highly effective mucolytic expectorant syrup. It reduces the viscosity of sputum. It is rapidly absorbed from the gastrointestinal tract. It crosses the blood brain barrier and small amounts cross the placenta.COMPOSITIONEach 5 ml syrup contains Bromhexine Hydrochloride BP 4 mg.INDICATIONSA-Cold (Bromhexine Hydrochloride) syrup is a mucolytic used in the treatment of respiratory disorders associated with productive cough. It is also indicated in the chronic bronchitis, acute & chronic bronchopulmonary diseases, pneumoconiosis and pulmonary emphysema.DOSAGE & ADMINISTRATIONAdults The recommended dose is 2 to 4 teaspoonful 3 times daily. Initially 4 teaspoonful 3 times daily and then as required. Children 5-10 years : 1 teaspoonful 3 times daily. 2-5 years : 1/2 teaspoonful 3 times daily. Under 2 years : 1/4 teaspoonful 3 times daily.OR AS DIRECTED BY THE PHYSICIAN. SIDE-EFFECTSGastro-intestinal side effects may occur occasionally with Bromhexine and a transient rise in serum aminotransferase values has been reported. Other reported adverse effects include headache, dizziness, sweating, and skin rashes.CONTRAINDICATIONSBromhexine Hydrochloride is contra-indicated in-patients with known hypersensitivity to any of the components of the drug.PRECAUTIONSSince mucolytics may disrupt the gastric mucosal barrier, Bromhexine should be used with care in-patients with a history of peptic ulceration. Care is also advisable in asthmatic patients. Clearance of Bromhexine or its metabolites may be reduced in patients with severe hepatic or renal impairment.SUPPLYEach pet bottle contains 100 ml syrup..
Tk.40.12/=
A-Fenac 25 mg Tab
A-Fenac 25DESCRIPTIONA-FENAC (Diclofenac Sodium) is a potent nonsteroidal, anti-inflammatory agentwith analgesic and antipyretic properties. By virtue of its analgesic, antipyreticand anti-inflammatory properties together with its excellent tolerability marks amajor advance in the treatment of rheumatic and or inflammatory conditions.Diclofenac inhibits cyclooxygenase activity with a reduction in the tissueproduction of prostaglandins.Tablet A-FENAC is enteric-coated (acid-resistant coating) with the result that the active constituent is not released until it has passed through the stomach. A-FENAC SR tablet has got many advantages. Because the frequency of drug administration is reduced, patient compliance can be improved and drug administration be made more convenient as well.COMPOSITIONTablet : Each enteric coated A-FENAC 25 tablet contains Diclofenac Sodium BP 25 mg.Each enteric coated A-FENAC 50 tablet contains Diclofenac Sodium BP 50 mg.Tablet SR : Each A-FENAC SR (sustained release) tablet contains Diclofenac Sodium BP 100 mg.Injection : Each 3 ml ampoule of A-FENAC injection contains 75 mg Diclofenac Sodium BP.Suppository : A-Fenac 12.5 : Each suppository contains declofenac sodium BP 12.5 mg.A-Fenac 50 : Each suppository contains diclofenac sodium BP 50 mg.A-FENAC Gel : Each 100 g A-FENAC Gel contains Diclofenac Diethylamine BP1.16 g equivalent to Diclofenac Sodium 1 g.INDICATIONSA-FENAC is indicated in the following cases : Rheumatoid arthritis, osteoarthritis, low back pain, injuries and manifestations of soft tissue rheumatism, ankylosing spondylitis, acute gout, control of pain & inflammation in orthopaedic, dental & other minor surgery, juvenile rheumatoid arthritis, postoperative pain, renal colic & other musculoskeletal disorders.DOSAGE & ADMINISTRATIONUsual dosing information : Tablet A-FENAC should be taken with water during or immediately after meals. Antacid should not be taken within 1-2 hours aftertaking tablet A-FENAC.Usual adult dose :A-FENAC Tablet : In adults, the initial dose is 25-50 mg three times a day, depending on the severity of the condition.A-FENAC SR Tablet : 75-150 mg once daily.Injection : For adults the usual dose is 1 ampoule daily. In serious cases this dose may be increased up to 2 ampoules daily.Suppository :Adult : 75-150 mg daily in divided doses.Children (1-12 years) : 1-3 mg/kg daily in divided dosesGel :Adult (>12 years) : A small amount (2-4 g) of A-FENAC Gel should be applied 3- 4 times daily to the affected area and rubbed lightly. Treatment is dependent on the size of the affected area. A-FENAC Gel may also be given in addition to further treatment with other dosage forms of Diclofenac.OR AS DIRECTED BY THE PHYSICIAN.CONTRAINDICATIONA-FENAC is contraindicated in peptic ulcer, previous sensitivity to Diclofenac Sodium and in asthmatic patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by Aspirin or other nonsteroidal anti-inflammatory agents with prostaglandin synthesis inhibiting activity.SIDE EFFECTSOccasional gastrointestinal disorders, headache, dizziness or vertigo, rash, elevation of SGOT/SGPT, rare peptic ulcer, gastro-intestinal bleeding, hepatitis, hypersensitivity reactions. In isolated cases, disturbances of sensation, erythema multiforme, purpura, abnormalities of renal function, blood dyscrasias may occur. PRECAUTIONSPrecaution should be taken in patients with symptoms/history of gastro-intestinal disease, impaired hepatic, cardiac or renal function, pregnancy, porphyria and patients who are taking diuretics, anticoagulant, or antidiabetics. During prolonged treatment, periodical monitoring of liver function should be carried out and blood counts are recommended. Possibility of hypersensitivity reactions to sodium disulphite particularly in patients with asthma.SUPPLYTablet :A-FENAC 25 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC 50 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC SR : Each box contains 10x10 tablets in blisters.Injection :A-FENAC : Each box contains 2x5 ampoules in blisters.Suppository :A-FENAC 12.5 : Each box contains 2x5 suppositories in blisters.A-FENAC 50 : Each box contains 2 x 5 suppositories in blisters.Gel :A-FENAC : Each tube contains 10 g gel...
Tk.0.55/=
A-Fenac 50 mg Tab
A-Fenac 50 TabDESCRIPTIONA-FENAC (Diclofenac Sodium) is a potent nonsteroidal, anti-inflammatory agentwith analgesic and antipyretic properties. By virtue of its analgesic, antipyreticand anti-inflammatory properties together with its excellent tolerability marks amajor advance in the treatment of rheumatic and or inflammatory conditions.Diclofenac inhibits cyclooxygenase activity with a reduction in the tissueproduction of prostaglandins.Tablet A-FENAC is enteric-coated (acid-resistant coating) with the result that the active constituent is not released until it has passed through the stomach. A-FENAC SR tablet has got many advantages. Because the frequency of drug administration is reduced, patient compliance can be improved and drug administration be made more convenient as well.COMPOSITIONTablet : Each enteric coated A-FENAC 25 tablet contains Diclofenac Sodium BP 25 mg.Each enteric coated A-FENAC 50 tablet contains Diclofenac Sodium BP 50 mg.Tablet SR : Each A-FENAC SR (sustained release) tablet contains Diclofenac Sodium BP 100 mg.Injection : Each 3 ml ampoule of A-FENAC injection contains 75 mg Diclofenac Sodium BP.Suppository : A-Fenac 12.5 : Each suppository contains declofenac sodium BP 12.5 mg.A-Fenac 50 : Each suppository contains diclofenac sodium BP 50 mg.A-FENAC Gel : Each 100 g A-FENAC Gel contains Diclofenac Diethylamine BP1.16 g equivalent to Diclofenac Sodium 1 g.INDICATIONSA-FENAC is indicated in the following cases : Rheumatoid arthritis, osteoarthritis, low back pain, injuries and manifestations of soft tissue rheumatism, ankylosing spondylitis, acute gout, control of pain & inflammation in orthopaedic, dental & other minor surgery, juvenile rheumatoid arthritis, postoperative pain, renal colic & other musculoskeletal disorders.DOSAGE & ADMINISTRATIONUsual dosing information : Tablet A-FENAC should be taken with water during or immediately after meals. Antacid should not be taken within 1-2 hours aftertaking tablet A-FENAC.Usual adult dose :A-FENAC Tablet : In adults, the initial dose is 25-50 mg three times a day, depending on the severity of the condition.A-FENAC SR Tablet : 75-150 mg once daily.Injection : For adults the usual dose is 1 ampoule daily. In serious cases this dose may be increased up to 2 ampoules daily.Suppository :Adult : 75-150 mg daily in divided doses.Children (1-12 years) : 1-3 mg/kg daily in divided dosesGel :Adult (>12 years) : A small amount (2-4 g) of A-FENAC Gel should be applied 3- 4 times daily to the affected area and rubbed lightly. Treatment is dependent on the size of the affected area. A-FENAC Gel may also be given in addition to further treatment with other dosage forms of Diclofenac.OR AS DIRECTED BY THE PHYSICIAN.CONTRAINDICATIONA-FENAC is contraindicated in peptic ulcer, previous sensitivity to Diclofenac Sodium and in asthmatic patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by Aspirin or other nonsteroidal anti-inflammatory agents with prostaglandin synthesis inhibiting activity.SIDE EFFECTSOccasional gastrointestinal disorders, headache, dizziness or vertigo, rash, elevation of SGOT/SGPT, rare peptic ulcer, gastro-intestinal bleeding, hepatitis, hypersensitivity reactions. In isolated cases, disturbances of sensation, erythema multiforme, purpura, abnormalities of renal function, blood dyscrasias may occur. PRECAUTIONSPrecaution should be taken in patients with symptoms/history of gastro-intestinal disease, impaired hepatic, cardiac or renal function, pregnancy, porphyria and patients who are taking diuretics, anticoagulant, or antidiabetics. During prolonged treatment, periodical monitoring of liver function should be carried out and blood counts are recommended. Possibility of hypersensitivity reactions to sodium disulphite particularly in patients with asthma.SUPPLYTablet :A-FENAC 25 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC 50 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC SR : Each box contains 10x10 tablets in blisters.Injection :A-FENAC : Each box contains 2x5 ampoules in blisters.Suppository :A-FENAC 12.5 : Each box contains 2x5 suppositories in blisters.A-FENAC 50 : Each box contains 2 x 5 suppositories in blisters.Gel :A-FENAC : Each tube contains 10 g gel...
Tk.0.84/=
A-Fenac 50mg Suppository
A-Fenac 50mg suppDESCRIPTIONA-FENAC (Diclofenac Sodium) is a potent nonsteroidal, anti-inflammatory agentwith analgesic and antipyretic properties. By virtue of its analgesic, antipyreticand anti-inflammatory properties together with its excellent tolerability marks amajor advance in the treatment of rheumatic and or inflammatory conditions.Diclofenac inhibits cyclooxygenase activity with a reduction in the tissueproduction of prostaglandins.Tablet A-FENAC is enteric-coated (acid-resistant coating) with the result that the active constituent is not released until it has passed through the stomach. A-FENAC SR tablet has got many advantages. Because the frequency of drug administration is reduced, patient compliance can be improved and drug administration be made more convenient as well.COMPOSITIONTablet : Each enteric coated A-FENAC 25 tablet contains Diclofenac Sodium BP 25 mg.Each enteric coated A-FENAC 50 tablet contains Diclofenac Sodium BP 50 mg.Tablet SR : Each A-FENAC SR (sustained release) tablet contains Diclofenac Sodium BP 100 mg.Injection : Each 3 ml ampoule of A-FENAC injection contains 75 mg Diclofenac Sodium BP.Suppository : A-Fenac 12.5 : Each suppository contains declofenac sodium BP 12.5 mg.A-Fenac 50 : Each suppository contains diclofenac sodium BP 50 mg.A-FENAC Gel : Each 100 g A-FENAC Gel contains Diclofenac Diethylamine BP1.16 g equivalent to Diclofenac Sodium 1 g.INDICATIONSA-FENAC is indicated in the following cases : Rheumatoid arthritis, osteoarthritis, low back pain, injuries and manifestations of soft tissue rheumatism, ankylosing spondylitis, acute gout, control of pain & inflammation in orthopaedic, dental & other minor surgery, juvenile rheumatoid arthritis, postoperative pain, renal colic & other musculoskeletal disorders.DOSAGE & ADMINISTRATIONUsual dosing information : Tablet A-FENAC should be taken with water during or immediately after meals. Antacid should not be taken within 1-2 hours aftertaking tablet A-FENAC.Usual adult dose :A-FENAC Tablet : In adults, the initial dose is 25-50 mg three times a day, depending on the severity of the condition.A-FENAC SR Tablet : 75-150 mg once daily.Injection : For adults the usual dose is 1 ampoule daily. In serious cases this dose may be increased up to 2 ampoules daily.Suppository :Adult : 75-150 mg daily in divided doses.Children (1-12 years) : 1-3 mg/kg daily in divided dosesGel :Adult (>12 years) : A small amount (2-4 g) of A-FENAC Gel should be applied 3- 4 times daily to the affected area and rubbed lightly. Treatment is dependent on the size of the affected area. A-FENAC Gel may also be given in addition to further treatment with other dosage forms of Diclofenac.OR AS DIRECTED BY THE PHYSICIAN.CONTRAINDICATIONA-FENAC is contraindicated in peptic ulcer, previous sensitivity to Diclofenac Sodium and in asthmatic patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by Aspirin or other nonsteroidal anti-inflammatory agents with prostaglandin synthesis inhibiting activity.SIDE EFFECTSOccasional gastrointestinal disorders, headache, dizziness or vertigo, rash, elevation of SGOT/SGPT, rare peptic ulcer, gastro-intestinal bleeding, hepatitis, hypersensitivity reactions. In isolated cases, disturbances of sensation, erythema multiforme, purpura, abnormalities of renal function, blood dyscrasias may occur. PRECAUTIONSPrecaution should be taken in patients with symptoms/history of gastro-intestinal disease, impaired hepatic, cardiac or renal function, pregnancy, porphyria and patients who are taking diuretics, anticoagulant, or antidiabetics. During prolonged treatment, periodical monitoring of liver function should be carried out and blood counts are recommended. Possibility of hypersensitivity reactions to sodium disulphite particularly in patients with asthma.SUPPLYTablet :A-FENAC 25 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC 50 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC SR : Each box contains 10x10 tablets in blisters.Injection :A-FENAC : Each box contains 2x5 ampoules in blisters.Suppository :A-FENAC 12.5 : Each box contains 2x5 suppositories in blisters.A-FENAC 50 : Each box contains 2 x 5 suppositories in blisters.Gel :A-FENAC : Each tube contains 10 g gel...
Tk.14.10/=
A-Fenac K 50 mg Tablet
A-Fenac K 50DESCRIPTIONA-FENAC K (Diclofenac Potassium) has a rapid onset of action, which makes it particularly suitable for the treatment of acute painful and inflammatory conditions. Inhibition of prostaglandin biosynthesis is considered to be fundamental to its mechanism of action. Diclofenac is rapidly and completely absorbed from A-FENAC K tablets. The absorption sets in immediately after administration.COMPOSITIONTablet : Each film-coated tablet contains Diclofenac Potassium INN 50 mg.INDICATIONSShort term treatment in the following acute conditions:• Post-traumatic pain, inflammation and swelling e.g., due to sprains.• Post-operative pain, inflammation and swelling, e.g., following dental or orthopaedic surgery.• Painful and/or inflammatory conditions in gynaecology, e.g., primary dysmenorrhoea.l• Painful syndromes of the vertebral column.• Non articular rheumatism.As an adjuvant in several painful inflammatory infections of the ear, nose or throat :• Pharyngotonsillitis.• Otitis media.DOSAGE AND ADMINISTRATIONAdults : The recommended initial daily dosage is 100-150 mg daily in 2-3 divided doses. In milder cases as well as for patients over 14 years 75-100 mg daily in 2-3 divided doses. In dysmenorrhoea the daily dosage should be individually adjusted and is generally 50- 150 mg. Children : It is not recommended for use in children. OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSOccasional epigastric pain, other gastrointestinal disorders such as nausea, vomiting, diarrhoea, abdominal cramps, dyspepsia, flatulence, anorexia etc. Occasional CNS problems such as headache, dizziness, vertigo etc.CONTRAINDICATIONSGastric or intestinal ulcer. Known hypersensitivity to the active substance or the excipients. Like other NSAIDs, Diclofenac Potassium is also contraindicated in active or suspected peptic ulcer or gastro-intestinal bleeding. Asthmatic patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or other nonsteroidal anti-inflammatory agents with possessing prosta-glandin synthetase inhibiting activity.PRECAUTIONSSymptoms or history of gastro-intestinal disease, impaired hepatic, cardiac or renal function. Use with caution in elderly patients.SUPPLYTablet : Each box contains 5 x 10 tablets in blisters...
Tk.3.01/=
A-Fenac SR Tablet 100 mg , 1 strip
A-Fenac SRDESCRIPTIONA-FENAC (Diclofenac Sodium) is a potent nonsteroidal, anti-inflammatory agentwith analgesic and antipyretic properties. By virtue of its analgesic, antipyreticand anti-inflammatory properties together with its excellent tolerability marks amajor advance in the treatment of rheumatic and or inflammatory conditions.Diclofenac inhibits cyclooxygenase activity with a reduction in the tissueproduction of prostaglandins.Tablet A-FENAC is enteric-coated (acid-resistant coating) with the result that the active constituent is not released until it has passed through the stomach. A-FENAC SR tablet has got many advantages. Because the frequency of drug administration is reduced, patient compliance can be improved and drug administration be made more convenient as well.COMPOSITIONTablet : Each enteric coated A-FENAC 25 tablet contains Diclofenac Sodium BP 25 mg.Each enteric coated A-FENAC 50 tablet contains Diclofenac Sodium BP 50 mg.Tablet SR : Each A-FENAC SR (sustained release) tablet contains Diclofenac Sodium BP 100 mg.Injection : Each 3 ml ampoule of A-FENAC injection contains 75 mg Diclofenac Sodium BP.Suppository : A-Fenac 12.5 : Each suppository contains declofenac sodium BP 12.5 mg.A-Fenac 50 : Each suppository contains diclofenac sodium BP 50 mg.A-FENAC Gel : Each 100 g A-FENAC Gel contains Diclofenac Diethylamine BP1.16 g equivalent to Diclofenac Sodium 1 g.INDICATIONSA-FENAC is indicated in the following cases : Rheumatoid arthritis, osteoarthritis, low back pain, injuries and manifestations of soft tissue rheumatism, ankylosing spondylitis, acute gout, control of pain & inflammation in orthopaedic, dental & other minor surgery, juvenile rheumatoid arthritis, postoperative pain, renal colic & other musculoskeletal disorders.DOSAGE & ADMINISTRATIONUsual dosing information : Tablet A-FENAC should be taken with water during or immediately after meals. Antacid should not be taken within 1-2 hours aftertaking tablet A-FENAC.Usual adult dose :A-FENAC Tablet : In adults, the initial dose is 25-50 mg three times a day, depending on the severity of the condition.A-FENAC SR Tablet : 75-150 mg once daily.Injection : For adults the usual dose is 1 ampoule daily. In serious cases this dose may be increased up to 2 ampoules daily.Suppository :Adult : 75-150 mg daily in divided doses.Children (1-12 years) : 1-3 mg/kg daily in divided dosesGel :Adult (>12 years) : A small amount (2-4 g) of A-FENAC Gel should be applied 3- 4 times daily to the affected area and rubbed lightly. Treatment is dependent on the size of the affected area. A-FENAC Gel may also be given in addition to further treatment with other dosage forms of Diclofenac.OR AS DIRECTED BY THE PHYSICIAN.CONTRAINDICATIONA-FENAC is contraindicated in peptic ulcer, previous sensitivity to Diclofenac Sodium and in asthmatic patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by Aspirin or other nonsteroidal anti-inflammatory agents with prostaglandin synthesis inhibiting activity.SIDE EFFECTSOccasional gastrointestinal disorders, headache, dizziness or vertigo, rash, elevation of SGOT/SGPT, rare peptic ulcer, gastro-intestinal bleeding, hepatitis, hypersensitivity reactions. In isolated cases, disturbances of sensation, erythema multiforme, purpura, abnormalities of renal function, blood dyscrasias may occur. PRECAUTIONSPrecaution should be taken in patients with symptoms/history of gastro-intestinal disease, impaired hepatic, cardiac or renal function, pregnancy, porphyria and patients who are taking diuretics, anticoagulant, or antidiabetics. During prolonged treatment, periodical monitoring of liver function should be carried out and blood counts are recommended. Possibility of hypersensitivity reactions to sodium disulphite particularly in patients with asthma.SUPPLYTablet :A-FENAC 25 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC 50 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC SR : Each box contains 10x10 tablets in blisters.Injection :A-FENAC : Each box contains 2x5 ampoules in blisters.Suppository :A-FENAC 12.5 : Each box contains 2x5 suppositories in blisters.A-FENAC 50 : Each box contains 2 x 5 suppositories in blisters.Gel :A-FENAC : Each tube contains 10 g gel...
Tk.30.10/=
A-Fenac12.5mg suppositore
A-Fenac12.5mg suppositoreDESCRIPTIONA-FENAC (Diclofenac Sodium) is a potent nonsteroidal, anti-inflammatory agentwith analgesic and antipyretic properties. By virtue of its analgesic, antipyreticand anti-inflammatory properties together with its excellent tolerability marks amajor advance in the treatment of rheumatic and or inflammatory conditions.Diclofenac inhibits cyclooxygenase activity with a reduction in the tissueproduction of prostaglandins.Tablet A-FENAC is enteric-coated (acid-resistant coating) with the result that the active constituent is not released until it has passed through the stomach. A-FENAC SR tablet has got many advantages. Because the frequency of drug administration is reduced, patient compliance can be improved and drug administration be made more convenient as well.COMPOSITIONTablet : Each enteric coated A-FENAC 25 tablet contains Diclofenac Sodium BP 25 mg.Each enteric coated A-FENAC 50 tablet contains Diclofenac Sodium BP 50 mg.Tablet SR : Each A-FENAC SR (sustained release) tablet contains Diclofenac Sodium BP 100 mg.Injection : Each 3 ml ampoule of A-FENAC injection contains 75 mg Diclofenac Sodium BP.Suppository : A-Fenac 12.5 : Each suppository contains declofenac sodium BP 12.5 mg.A-Fenac 50 : Each suppository contains diclofenac sodium BP 50 mg.A-FENAC Gel : Each 100 g A-FENAC Gel contains Diclofenac Diethylamine BP1.16 g equivalent to Diclofenac Sodium 1 g.INDICATIONSA-FENAC is indicated in the following cases : Rheumatoid arthritis, osteoarthritis, low back pain, injuries and manifestations of soft tissue rheumatism, ankylosing spondylitis, acute gout, control of pain & inflammation in orthopaedic, dental & other minor surgery, juvenile rheumatoid arthritis, postoperative pain, renal colic & other musculoskeletal disorders.DOSAGE & ADMINISTRATIONUsual dosing information : Tablet A-FENAC should be taken with water during or immediately after meals. Antacid should not be taken within 1-2 hours aftertaking tablet A-FENAC.Usual adult dose :A-FENAC Tablet : In adults, the initial dose is 25-50 mg three times a day, depending on the severity of the condition.A-FENAC SR Tablet : 75-150 mg once daily.Injection : For adults the usual dose is 1 ampoule daily. In serious cases this dose may be increased up to 2 ampoules daily.Suppository :Adult : 75-150 mg daily in divided doses.Children (1-12 years) : 1-3 mg/kg daily in divided dosesGel :Adult (>12 years) : A small amount (2-4 g) of A-FENAC Gel should be applied 3- 4 times daily to the affected area and rubbed lightly. Treatment is dependent on the size of the affected area. A-FENAC Gel may also be given in addition to further treatment with other dosage forms of Diclofenac.OR AS DIRECTED BY THE PHYSICIAN.CONTRAINDICATIONA-FENAC is contraindicated in peptic ulcer, previous sensitivity to Diclofenac Sodium and in asthmatic patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by Aspirin or other nonsteroidal anti-inflammatory agents with prostaglandin synthesis inhibiting activity.SIDE EFFECTSOccasional gastrointestinal disorders, headache, dizziness or vertigo, rash, elevation of SGOT/SGPT, rare peptic ulcer, gastro-intestinal bleeding, hepatitis, hypersensitivity reactions. In isolated cases, disturbances of sensation, erythema multiforme, purpura, abnormalities of renal function, blood dyscrasias may occur. PRECAUTIONSPrecaution should be taken in patients with symptoms/history of gastro-intestinal disease, impaired hepatic, cardiac or renal function, pregnancy, porphyria and patients who are taking diuretics, anticoagulant, or antidiabetics. During prolonged treatment, periodical monitoring of liver function should be carried out and blood counts are recommended. Possibility of hypersensitivity reactions to sodium disulphite particularly in patients with asthma.SUPPLYTablet :A-FENAC 25 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC 50 : Each box contains 10x10 enteric coated tablets in blisters.A-FENAC SR : Each box contains 10x10 tablets in blisters.Injection :A-FENAC : Each box contains 2x5 ampoules in blisters.Suppository :A-FENAC 12.5 : Each box contains 2x5 suppositories in blisters.A-FENAC 50 : Each box contains 2 x 5 suppositories in blisters.Gel :A-FENAC : Each tube contains 10 g gel...
Tk.8.07/=
A-Migel 30 gm Gel
A-Migel 30 gm GelDescriptionMiconazole is a synthetic imidazole anti-fungal agent with a broadspectrum of activity against pathogenic fungi (including yeast and dermatophytes) and gram-positive bacteria (Staphylococcus and Streptococcus spp). It may act by interfering with the permeability of the fungal cell membranes. Miconazole oral gel is incompletely absorbed from the gastrointestinal tract. Miconazole is inactivated in the body and 10-20% of an oral dose is excreted in the urine.CompositionEach gram oral gel contains 20 mg Miconazole USP.IndicationOral treatment and prevention of fungal infections of the oropharynx and gastrointestinal tract.Dosage and AdministrationFor oral administration : Dosage is based on 15 mg/kg/day after meal. Adults : 1-2 tea-spoonfuls of gel four times daily.Children aged 6 years and over : One tea-spoonful of gel four times daily.Children aged 2-6 years : One tea-spoonful of gel twice daily. Infants under 2 years : Half tea-spoonful of gel twice daily. For localised lesions of the mouth, a small amount of A-Migel oral gel may be applied directly to the affected area with a clean finger 2-4 times daily. For topical treatment of the oropharynx, the gel should be kept in the mouth for as long as possible. Treatment should be continued for up to 2 days after the symptoms have cleared. For oral candidiasis, dental prostheses should be removed at night and brushed with the gel.OR AS DIRECTED BY THE PHYSICIANSide effectsOccasionally, nausea and vomiting have been reported and with long term treatment, diarrhoea is also reported.ContraindicationsMiconazole is contraindicated in patients with known hypersensitivity to the active drug and imidazole group.PrecautionThe concomitant use of Miconazole with anti-coagulant, anti-epileptic and anti-diabetic drugs increases the affectivity of these drugs. So dosage of Miconazole should be revised.Use in Pregnancy & LactationIn animals Miconazole has shown no teratogenic effects but is foetotoxic at high oral doses. However, as with other imidazoles, Miconazole Oral Gel should be avoided in pregnant women if possible. The potential hazards should be balanced against the possible benefits. It is not known whether Miconazole is excreted in human milk. Caution should be exercised when prescribing Miconazole Oral Gel to nursing mothers.Over dosageIn general, Miconazole is not highly toxic. In the event of accidental over dosage, vomiting and diarrhoea may occur.SupplyOral Gel : Each carton contains 15 gm oral gel in tube and a spoon...
Tk.90.00/=
A-Phenicol Drop 10 ml drop
A-Phenicol Drop 10 ml dropDESCRIPTIONChloramphenicol is a broad spectrum antibiotic, isolated in 1947 from streptomyces venezuelae. It is primarily bacteriostatic and acts by inhibition of protein synthesis. It has been noted that chloramphenicol is found in measurable amounts in the aqueous humor following local application to the eye. Development of resistance to Chloramphenicol is minimum for staphylococci and many other species of bacteria.COMPOSITIONEYE OINTMENT : Each gm contains 10 mg of Chloramphenicol BP in a special base. It is a sterile eye ointment.EYE/EAR DROPS : Each ml eye/ear drops contains Chloramphenicol BP 5 mg. It is a sterile eye / ear drops.INDICATIONSA-PHENICOL is indicated in surface ocular infections involving the conjunctiva and/or cornea caused by Chloramphenicol susceptible organisms. A-PHENICOL is also active against common bacterial pathogens, E.coli, Klebsiella, Niesseria sp., H.influenzae, Enterobacter sp., Staphylococcus aureus and Streptococcus pneumoniae.A-PHENICOL is also indicated in ear canal infection.DOSAGE AND ADMINISTRATIONA-PHENICOL Eye OintmentA PHENICOL eye ointment should be used every three hours. Administration should be continued day and night for the first 48 hours after which the interval between application may be increased and continued for at least 2 days after the eye appears normal.A-PHENICOL Eye/Ear DropsFor eye : 2 drops of solution every 1 hour, until condition improves or instill 4 times daily depending on severity of infection. For ear : (Adult & Children) : 2 or 3 drops in the affected ear 2-3 times daily. OR AS DIRECTED BY THE PHYSICIAN.CONTRAINDICATIONSChloramphenicol is contraindicated in patients sensitive to any of its components.PRECAUTIONSOphthalmic ointments may retard corneal wound healing. So patients with corneal disease should take precautions while using this medicine.SUPPLYA-PHENICOL Eye Ointment : A-PHENICOL Eye Ointment is supplied in 5 gmcollapsible tube.A-PHENICOL Eye/Ear Drops : A-PHENICOL Eye/Ear Drops is supplied in 10 mlplastic bottle with dropper...
Tk.34.50/=
A-Phenicol Eye Ointment 5g
A-Phenicol Eye Ointment 5gDESCRIPTIONChloramphenicol is a broad spectrum antibiotic, isolated in 1947 from streptomyces venezuelae. It is primarily bacteriostatic and acts by inhibition of protein synthesis. It has been noted that chloramphenicol is found in measurable amounts in the aqueous humor following local application to the eye. Development of resistance to Chloramphenicol is minimum for staphylococci and many other species of bacteria.COMPOSITIONEYE OINTMENT : Each gm contains 10 mg of Chloramphenicol BP in a special base. It is a sterile eye ointment.EYE/EAR DROPS : Each ml eye/ear drops contains Chloramphenicol BP 5 mg. It is a sterile eye / ear drops.INDICATIONSA-PHENICOL is indicated in surface ocular infections involving the conjunctiva and/or cornea caused by Chloramphenicol susceptible organisms. A-PHENICOL is also active against common bacterial pathogens, E.coli, Klebsiella, Niesseria sp., H.influenzae, Enterobacter sp., Staphylococcus aureus and Streptococcus pneumoniae.A-PHENICOL is also indicated in ear canal infection.DOSAGE AND ADMINISTRATIONA-PHENICOL Eye OintmentA PHENICOL eye ointment should be used every three hours. Administration should be continued day and night for the first 48 hours after which the interval between application may be increased and continued for at least 2 days after the eye appears normal.A-PHENICOL Eye/Ear DropsFor eye : 2 drops of solution every 1 hour, until condition improves or instill 4 times daily depending on severity of infection. For ear : (Adult & Children) : 2 or 3 drops in the affected ear 2-3 times daily. OR AS DIRECTED BY THE PHYSICIAN.CONTRAINDICATIONSChloramphenicol is contraindicated in patients sensitive to any of its components.PRECAUTIONSOphthalmic ointments may retard corneal wound healing. So patients with corneal disease should take precautions while using this medicine.SUPPLYA-PHENICOL Eye Ointment : A-PHENICOL Eye Ointment is supplied in 5 gmcollapsible tube.A-PHENICOL Eye/Ear Drops : A-PHENICOL Eye/Ear Drops is supplied in 10 mlplastic bottle with dropper...
Tk.11.70/=
A-Phenicol-D Ophthalmic Solution 5 ml drop
A-Phenicol-D Ophthalmic Solution 5 ml dropIndications: Acute purulent conjunctivitis; fresh inflammation of the superficial and deeper corneal layers and corneal ulceration. Keratitis disciformis and the more deep-seated forms of post-herpetic keratitis. Allergic conjunctivitis, allergic blepharitis. Acute and chronic iritis and iridocyclitis.Dosage and AdministrationOne drop into the lower eyelid of the infected eye(s), 1-4 times daily. In acute cases 1 drop every hour. OR AS DIRECTED BY THE PHYSICIAN.Side Effects: Local use of dexamethasone over a prolonged period may lead in some cases to secondary glaucoma and the development of complicated cataract.Precautions and Contraindications: It must be used under strict medical supervision because of the possibility of inducing corneal abscess, fungal keratopathy or glaucoma. The patient should be referred to an ophthalmologist if the eye has not responded within 48 hours.Use in Pregnancy & Lactation: The safety of this combination during pregnancy has not yet been established. It is not known whether ingredients of this ophthalmic preparation is excreted in human milk. Therefore caution should be observed when it is administered to a nursing mother.Drug Interactions: Specific drug interaction studies have not been conducted with this combination.Supply: Each pack contains 5 ml sterile eye drops in plastic dropper bottle...
Tk.70.21/=
A-Zyme 325 mg Tablet, 1 strip
A-Zyme 325 mg Tablet, 1 stripDESCRIPTIONA-Zyme (Pancreatin) is a preparation of Pancreatin, an extract from mammalian pancreas containing enzymes with Amylase, Protease and Lipase activity. It is designed to disintegrate in the alkaline medium of the duodenum where it releases the active enzyme components of Pancreatin (Amylase, Protease and Lipase). Amylase hydrolyzes dietary starch to yield maltose, maltoriose and adextrin. Protease cleaves peptide bonds in the center of proteins and polypeptides and forms amino acids and oligopeptides. Lipase hydrolyzes dietary triglycerides forming two molecules of fatty acid and a molecule of betamonoglyceride. It converts not less than 25 times its weight of starch into soluble carbohydrates and not less than 25 times its weight of casein into proteoses within 5 mins. (equivalent to 150 times in 30 mins).COMPOSITIONEach enteric-film-coated tablet contains 325 mg of Pancreatin BP that provides not less than the following enzymatic activityAmylase 7800 units Protease 455 units Lipase 6500 unitsINDICATIONSA-Zyme is employed for the treatment of patients with● Chronic pancreatitis● Cystic fibrosis/Mucoviscidosis● Following partial or complete pancreatectomy● Total gastrectomy● Steatorrhea● Somatostatinoma● Celiac disease and● Other conditions associated with pancreatic insufficiency.DOSAGE AND ADMINISTRATION2-3 tablets to be swallowed whole with little water immediately after or during meal.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSThe most frequent side effects are gastrointestinal including nausea, vomiting and abdominal discomfort. Buccal and perianal soreness may occur, particularly in infants. Hypersensitivity reactions manifested by sneezing, lacrimation or skin rashes have been reported.CONTRAINDICATIONSPancreatin is contraindicated in patients with known hypersensitivity to the drug.PRECAUTIONSPatients known to be allergic to animal protein should be treated with caution.USE IN PREGNANCY AND LACTATIONPancreatin should be given to a pregnant woman only if clearly needed. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Pancreatin is administered to a nursing mother.DRUG INTERACTIONSAlkaline media will rupture the enteric coating. As such to prevent bursting out of the content in the stomach Pancreatin should not be used concurrently with antacid.OVERDOSAGEExcessive dosage may produce a laxative effect. Systemic toxicity does not occur. Very high dosage may cause hyperuricaemia and hyperuricosuria.SUPPLYEach box contains 10 X 10 tablets in strips...
Tk.35.10/=
Acelex 250 mg Capsule
AcelexIndicationsCephalexin is indicated for the treatment of the following infections when caused by susceptible organisms.Respiratory tract infections: Acute and chronic bronchitis and infected bronchiectasis.Genito-urinary tract infections: Acute and chronic nephritis, cystitis, urethritis and prostatitis, prophylaxis of recurrent urinary tract infections.Skin and soft tissue infections: Caused by staphylococci and/or streptococci.Ear, Nose and Throat infections: Otitis media, mastoiditis, sinusitis, follicular tonsillitis and pharyngitis.Bone infections: Caused by staphylococci and/or P. mirabilis.PharmacologyCephalexin is a semisynthetic analogue of Cephalosporin C. It kills bacteria by interfering in the synthesis of the bacterial cell wall. Peptidoglycan is a heteropolymeric structure that provides the cell wall with mechanical stability. The final stage in the synthesis of peptidoglycan involves the completion of the cross-linking and the terminal glycine residue of the Pentaglycine Bridge is linked to the fourth residue of the pentapeptide (d-alanin). The transpeptidase enzyme that performs this step is inhibited by penicillins and cephalosporins. As a result the bacterial cell wall is weakened, the cell swells and then ruptures. Cephalexin is a first generation cephalosporin that is active by mouth.Dosage & AdministrationAdult:The usual dose is 250 mg to 500 mg every 6 hour.For skin and soft tissue infections, streptococcal pharyngitis and uncomplicated cystitis, in patients over 15 years of age: 500 mg of the drug may be administered every 12 hour.In severe or deep seated infections the dose can be increased up to 3 g to 6 g daily.Children: The dosage range is 25-100 mg/kg/day in divided doses to a maximum of 4 g dailyChildren’s Weight Recommended Dose:10 kg (22 Ibs): 62.5 mg to 125 mg qid or 125 mg to 250 mg bid20 kg (44 Ibs): 125 mg to 250 mg qid or 250 mg to 500 mg bid40 kg (88 Ibs): 250 mg to 500 mg qid or 500 mg to 1 g bidFor streptococcal pharyngitis, skin and soft tissue infections and in patients over 1 year of age the total daily dose may be divided and administered every 12 hour. In the therapy of otitis media 75-100 mg/kg/day in four divided doses may be required. In the treatment of β haemolytic streptococcal infections a therapeutic dosage of the drug should be given at least for 10 days.ContraindicationsCephalen is contraindicated in patients with known hypersensitivity to the cephalosporin group of antibiotics.Side EffectsSide effects include nausea, vomiting, diarrhoea and abdominal discomfort. Symptoms of pseudomembranous colitis may appear either during or after antibiotic treatment. Skin rash, angio oedema, rise in serum aminotransferases, eosinophilia, neutropenia have been reported very rarely. Superinfection with resistant micro organisms, particularly candida may follow the treatment.Pregnancy & LactationPregnancy Category B. Cefalexin may be used during pregnancy when it is considered essential. Cefalexin is found in the milk of nursing mothers, hence caution should be taken when it is administered to nursing mothers.Precautions & WarningsCefalexin should be given with caution in patients with renal impairment. Under such condition, careful clinical observation should be made because safe dosage may be lower than the usually recommended. The urine of patients receiving Cefalexin may give a false positive reaction for glucose with copper reduction reagent. Positive results to Coombs’ test have been reported. Although there is no evidence of teratogenicity in animal tests, Cefalexin may be used during pregnancy when it is considered essential. Cefalexin is found in the milk of nursing mothers, hence caution should be taken when it is administered to nursing mothers.Storage ConditionsShould be stored in cool and dry place...
Tk.6.60/=
Acemox 250 mg Tablet, 1 strip
Acemox 250 mg Tablet, 1 stripDESCRIPTIONACEMOX (Acetazolamide) is a carbonic anhydrase inhibitor. This enzyme catalyzes the reversible reaction involving the hydration of carbon-di-oxide and the dehydration of carbonic acid. In the eye, this inhibitory action of ACEMOX (Acetazolamide) decreases the secretion of aqueous humor and results in a drop in intraocular pressure, a reaction considered desirable in case of glaucoma. Inhibition of carbonic anhydrase in the central nervous system appears to retard abnormal paroxysmal and excessive discharge from central nervous system neurons. So, ACEMOX (Acetazolamide) is also used as an adjuvant in the treatment of epilepsy.COMPOSITIONTablet : Each tablet contains Acetazolamide BP 250 mg.INDICATIONSOpen angle glaucoma, secondary glaucoma and as an adjuvant in the treatment of edema and epilepsy.DOSAGE AND ADMINISTRATIONAdults : Initially 1 tablet 4 times daily. Dose should be adjusted later with individual need. Children : ½-2 tablets in divided doses. In intraocular pressure: 1 tablet 6 hourly. In acute condition, dose should be started with 2 tablets followed by 1 tablet 6 hourly.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSHeadache, drowsiness, dizziness, fatigue, anorexia, polyurea, insomnia, gastrointestinal upset.CONTRAINDICATIONSAcetazolamide is contraindicated in cases of marked kidney and liver diseases or dysfunction, in situations in which sodium and or potassium blood serum levels decreased. Acetazolamide is also contraindicated in patients with chronic noncongestive angle closure glaucoma.PRECAUTIONSThere are no adequate and well controlled studies in pregnant women and neonates. So, Acetazolamide should be used with care in those physiological conditions.SUPPLYTablet : Each box contains 10 x 10 tablets in strips...
Tk.20.00/=
Aclobet 0.05% Ointment 10 gm tube
Aclobet 0.05% Ointment 10 gm tubeCOMPOSITIONAclobet Ointment : Each gram contains Clobetasol Propionate BP 0.5 mg.Aclobet Cream : Each gram contains Clobetasol Propionate BP 0.5 mg.PHARMACOLOGYClobetasol Propionate is a highly potent topical steroid. It has both local anti-inflammatory and immunosuppressive activity. Clobetasol, as the Propionate salt, is only used topically on the skin and its effects are limited to the local anti-inflammatory activity. When given systemically it has standard glucocorticoid activity and binds with high affinity to the glucocorticoid receptor. Clobetasol Propionate inhibits the adherence of neutrophils and monocyte-macrophages to the capillary endothelial cells inflammed area. Clobetasol blocks the effect of macrophage migration inhibitory factor and decreases the activation of plasminogen to plasmin.INDICATIONSAclobet is indicated in :• Initial control of all forms of hyperacute eczema in all age groups (in children for no longer than a few days).• Chronic hyperkeratotic eczema of the hands and feet and patches of chronic lichen simplex.• Chronic hyperkeratotic psoriasis of any area of the body.• Severe acute photosensitivity.• Hypertrophic lichen planus.• Localized bullous disorders.• Keloid scarring.• Pretibial myxoedema.• Vitiligo.• Suppression of reaction after cryotherapy.DOSAGE AND ADMINISTRATIONRoute of AdministrationApply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations, therapy should be discontinued when control is achieved. If a longer course is necessary, it is recommended that treatment should not be continued for more than four weeks without the patients condition being observed. Repeated short courses of Aclobet may be used to control exacerbations. If continuous steroid treatment is necessary a less potent preparation should be used. In very resistant lesions, especially where there is hyperkeratosis, the anti-inflammatory effects of Aclobet can be enhanced, if necessary, by occluding the treatment area with polythene film. Only overnight occlusion is usually adequate to bring about a satisfactory response. Thereafter, improvement can usually be maintained by application without occlusion.CONTRAINDICATIONS AND PRECAUTIONClobetasol Propionate is contraindicated in :• Cutaneous infections such as impetigo, tinea corporis and herpes simplex.• Infestations such as scabies.• Neonates.• Acne Vulgaris.• Rosacea.• Gravitational ulceration.Long term continuous therapy with Clobetasol Propionate should be avoided, particularly in infants and children, in whom adrenal suppression occurs readily. If Clobetasol Propionate is required for use in children, it is recommended that the treatment should be reviewed on weekly basis. It should be noted that the infant’s napkin might act asocclusive dressing. The face more than other area of the body, may exhibit atrophic changes after prolonged treatment with potent topical corticosteroids. This must be borne in mind when treating facial conditions which warrants use of Clobetasol Propionate and frequent observation of the patient is important.SIDE EFFECTSCommon side effects : Provided the weekly dosage is less then 50 g in adults, any pituitary adrenal suppression is likely to be transient with a rapid return to normal values once the short course of steroid therapy has ceased. The same applies to children given proportionate dosage. Use of occlusive dressings increases the absorption of topical corticosteroids. Prolonged and intensive treatment with a highly active corticosteroid preparation may cause atrophic changes, such as thinning, striae and dilatation of the superficial blood vessels, particularly when occlusive dressings are used or where skin folds are involved.Rare side effects :USE IN PREGNANCY & LACTATIONClobetasol Propionate should be avoided in pregnant women. Mothers using large amounts of the drug should be aware of potential excretion in milk.USE IN CHILDREN & ADOLESCENTDRUG INTERACTIONWith medicine :With food & others :OVER DOSEAcute overdose is very unlikely to occur. However, in the case of chronic over dosage or misuse, the features of hypercorticisms may appear and in this situation topical steroids should be discontinued.STORAGEStore below 300 C and dry place, protected from light. Keep all medicines out of reach of children.PACKINGAclobet Ointment : Each pack contains 10 gm Ointment in tube.Aclobet Cream : Each pack contains 10 gm Cream in tube...
Tk.50.14/=
Aclobet 10 gm cream
Aclobet 10 gm creamCOMPOSITIONAclobet Ointment : Each gram contains Clobetasol Propionate BP 0.5 mg.Aclobet Cream : Each gram contains Clobetasol Propionate BP 0.5 mg.PHARMACOLOGYClobetasol Propionate is a highly potent topical steroid. It has both local anti-inflammatory and immunosuppressive activity. Clobetasol, as the Propionate salt, is only used topically on the skin and its effects are limited to the local anti-inflammatory activity. When given systemically it has standard glucocorticoid activity and binds with high affinity to the glucocorticoid receptor. Clobetasol Propionate inhibits the adherence of neutrophils and monocyte-macrophages to the capillary endothelial cells inflammed area. Clobetasol blocks the effect of macrophage migration inhibitory factor and decreases the activation of plasminogen to plasmin.INDICATIONSAclobet is indicated in :• Initial control of all forms of hyperacute eczema in all age groups (in children for no longer than a few days).• Chronic hyperkeratotic eczema of the hands and feet and patches of chronic lichen simplex.• Chronic hyperkeratotic psoriasis of any area of the body.• Severe acute photosensitivity.• Hypertrophic lichen planus.• Localized bullous disorders.• Keloid scarring.• Pretibial myxoedema.• Vitiligo.• Suppression of reaction after cryotherapy.DOSAGE AND ADMINISTRATIONRoute of AdministrationApply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations, therapy should be discontinued when control is achieved. If a longer course is necessary, it is recommended that treatment should not be continued for more than four weeks without the patients condition being observed. Repeated short courses of Aclobet may be used to control exacerbations. If continuous steroid treatment is necessary a less potent preparation should be used. In very resistant lesions, especially where there is hyperkeratosis, the anti-inflammatory effects of Aclobet can be enhanced, if necessary, by occluding the treatment area with polythene film. Only overnight occlusion is usually adequate to bring about a satisfactory response. Thereafter, improvement can usually be maintained by application without occlusion.CONTRAINDICATIONS AND PRECAUTIONClobetasol Propionate is contraindicated in :• Cutaneous infections such as impetigo, tinea corporis and herpes simplex.• Infestations such as scabies.• Neonates.• Acne Vulgaris.• Rosacea.• Gravitational ulceration.Long term continuous therapy with Clobetasol Propionate should be avoided, particularly in infants and children, in whom adrenal suppression occurs readily. If Clobetasol Propionate is required for use in children, it is recommended that the treatment should be reviewed on weekly basis. It should be noted that the infant’s napkin might act asocclusive dressing. The face more than other area of the body, may exhibit atrophic changes after prolonged treatment with potent topical corticosteroids. This must be borne in mind when treating facial conditions which warrants use of Clobetasol Propionate and frequent observation of the patient is important.SIDE EFFECTSCommon side effects : Provided the weekly dosage is less then 50 g in adults, any pituitary adrenal suppression is likely to be transient with a rapid return to normal values once the short course of steroid therapy has ceased. The same applies to children given proportionate dosage. Use of occlusive dressings increases the absorption of topical corticosteroids. Prolonged and intensive treatment with a highly active corticosteroid preparation may cause atrophic changes, such as thinning, striae and dilatation of the superficial blood vessels, particularly when occlusive dressings are used or where skin folds are involved.Rare side effects :USE IN PREGNANCY & LACTATIONClobetasol Propionate should be avoided in pregnant women. Mothers using large amounts of the drug should be aware of potential excretion in milk.USE IN CHILDREN & ADOLESCENTDRUG INTERACTIONWith medicine :With food & others :OVER DOSEAcute overdose is very unlikely to occur. However, in the case of chronic over dosage or misuse, the features of hypercorticisms may appear and in this situation topical steroids should be discontinued.STORAGEStore below 300 C and dry place, protected from light. Keep all medicines out of reach of children.PACKINGAclobet Ointment : Each pack contains 10 gm Ointment in tube.Aclobet Cream : Each pack contains 10 gm Cream in tube...
Tk.45.13/=
Aclobet-N 15 gm cream
Aclobet-N creamDESCRIPTIONClobetasol Propionate is a highly active corticosteroid with topical antiinflammatory activity. The major effect of Clobetasol Propionate on skin is a nonspecific anti-inflammatory response, partially due to vasoconstriction and decrease in collagen synthesis. Neomycin Sulphate is a broad spectrum antibiotic of the aminoglycoside type and is used to treat infections with bacteria. Nystatin is an antifungal medicine that kills fungi and yeasts by interfering with their cell membranes. The principle action of the preparation is based on the anti-inflammatory activity of the corticosteroid. The broad spectrum antibacterial and anti-candidal activity provided by the combination of Neomycin and Nystatin allow this effect to be utilized in the treatment of conditions which are or are likely to become infected.COMPOSITIONAclobet-N Cream : Each gram contains Clobetasol Propionate BP 0.5 mg, Neomycin Sulphate USP 5 mg and Nystatin USP 100000 units.Aclobet-N Ointment : Each gram contains Clobetasol Propionate BP 0.5 mg,Neomycin Sulphate USP 5 mg and Nystatin USP 100000 units.INDICATIONS AND USAGE Eczema unresponsive to weak steroid cream or ointment. Other inflammatory skin disorders resistant to treatment with weaker steroid cream or ointment . Psoriasis. Any inflammatory skin disorders where secondary bacterial or candidal infection is present, suspected or likely to occur.DOSAGE AND ADMINISTRATIONAdults and children above 2 years : Apply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations therapy should be discontinued when control is achieved. In very resistant lesions, especially where there is hyperkeratosis, the antiinflammatory effect of this preparation can be enhanced, if necessary, by occluding the treatment area with polythene. Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patients condition being reviewed. Repeated short courses of Aclobet - N may be used to control exacerbations.Elderly :This preparation is suitable for use in the elderly. Caution should be exercised in cases where a decrease in renal function exists and significant systemic absorption of neomycin sulphate may occur.Children : Under 2 years this preparation is not recommended.SIDE EFFECTSGenerally this preparation is well tolerated. However, few side effects after prolonged and intensive treatment may cause local atrophic changes in the skin such as thinning, striae, and dilatation of the superficial blood vessels, particularly when occlusive dressings are used or when skin folds are involved.CONTRAINDICATIONSIt is contraindicated in rosacea, acne vulgaris, perioral dermatitis, primary cutaneous viral infections (e.g herpes simplex, chickenpox), otitis externa with a perforated eardrum, hypersensitivity to the preparations.PRECAUTIONSLong term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur readily even without occlusion. If use in childhood, or on the face, courses should be limited to 5 days and occlusion should not be used. If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye. If used in psoriasis careful patient supervision is important.USE IN PREGNANCY & LACTATIONThe safe use of this preparation during pregnancy & lactation has not been established.DRUG INTERACTIONSNeomycin sulphate can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents following significant systemic absorption, if used in accordance with the recommendations systemic exposure to Neomycin Sulphate is expected to be minimal and drug interactions are unlikely to be significant. No hazardous interactions have been reported with use of Clobetasol Propionate or Nystatin.OVER DOSEAcute over dosage is very unlikely to occur, however, in the case of chronic overdosage or misuse the features of hypercortisolism may appear and in this situation topical steroids should be discontinued gradually. Also, consideration should be given to significant systemic absorption of Neomycin Sulphate. If this is suspected, use of the product should be stopped and the patient’s general status, hearing acuity, renal and neuromuscular functions should be monitored. Haemodialysis may reduce the serum level of Neomycin Sulphate.SUPPLYAclobet-N Cream : Each pack contains 15 gm cream in a tube.Aclobet-N Ointment : Each pack contains 15 gm ointment in a tube..
Tk.60.18/=
Aclobet-N 15 gm Oint
Aclobet-N OintDESCRIPTIONClobetasol Propionate is a highly active corticosteroid with topical antiinflammatory activity. The major effect of Clobetasol Propionate on skin is a nonspecific anti-inflammatory response, partially due to vasoconstriction and decrease in collagen synthesis. Neomycin Sulphate is a broad spectrum antibiotic of the aminoglycoside type and is used to treat infections with bacteria. Nystatin is an antifungal medicine that kills fungi and yeasts by interfering with their cell membranes. The principle action of the preparation is based on the anti-inflammatory activity of the corticosteroid. The broad spectrum antibacterial and anti-candidal activity provided by the combination of Neomycin and Nystatin allow this effect to be utilized in the treatment of conditions which are or are likely to become infected.COMPOSITIONAclobet-N Cream : Each gram contains Clobetasol Propionate BP 0.5 mg, Neomycin Sulphate USP 5 mg and Nystatin USP 100000 units.Aclobet-N Ointment : Each gram contains Clobetasol Propionate BP 0.5 mg,Neomycin Sulphate USP 5 mg and Nystatin USP 100000 units.INDICATIONS AND USAGE Eczema unresponsive to weak steroid cream or ointment. Other inflammatory skin disorders resistant to treatment with weaker steroid cream or ointment . Psoriasis. Any inflammatory skin disorders where secondary bacterial or candidal infection is present, suspected or likely to occur.DOSAGE AND ADMINISTRATIONAdults and children above 2 years : Apply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations therapy should be discontinued when control is achieved. In very resistant lesions, especially where there is hyperkeratosis, the antiinflammatory effect of this preparation can be enhanced, if necessary, by occluding the treatment area with polythene. Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patients condition being reviewed. Repeated short courses of Aclobet - N may be used to control exacerbations.Elderly :This preparation is suitable for use in the elderly. Caution should be exercised in cases where a decrease in renal function exists and significant systemic absorption of neomycin sulphate may occur.Children : Under 2 years this preparation is not recommended.SIDE EFFECTSGenerally this preparation is well tolerated. However, few side effects after prolonged and intensive treatment may cause local atrophic changes in the skin such as thinning, striae, and dilatation of the superficial blood vessels, particularly when occlusive dressings are used or when skin folds are involved.CONTRAINDICATIONSIt is contraindicated in rosacea, acne vulgaris, perioral dermatitis, primary cutaneous viral infections (e.g herpes simplex, chickenpox), otitis externa with a perforated eardrum, hypersensitivity to the preparations.PRECAUTIONSLong term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur readily even without occlusion. If use in childhood, or on the face, courses should be limited to 5 days and occlusion should not be used. If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye. If used in psoriasis careful patient supervision is important.USE IN PREGNANCY & LACTATIONThe safe use of this preparation during pregnancy & lactation has not been established.DRUG INTERACTIONSNeomycin sulphate can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents following significant systemic absorption, if used in accordance with the recommendations systemic exposure to Neomycin Sulphate is expected to be minimal and drug interactions are unlikely to be significant. No hazardous interactions have been reported with use of Clobetasol Propionate or Nystatin.OVER DOSEAcute over dosage is very unlikely to occur, however, in the case of chronic overdosage or misuse the features of hypercortisolism may appear and in this situation topical steroids should be discontinued gradually. Also, consideration should be given to significant systemic absorption of Neomycin Sulphate. If this is suspected, use of the product should be stopped and the patient’s general status, hearing acuity, renal and neuromuscular functions should be monitored. Haemodialysis may reduce the serum level of Neomycin Sulphate.SUPPLYAclobet-N Cream : Each pack contains 15 gm cream in a tube.Aclobet-N Ointment : Each pack contains 15 gm ointment in a tube..
Tk.65.45/=
Acme's Dextrose DS 1000 ml IV Infusion
Acme's Dextrose DS 1000 ml IV InfusionDESCRIPTIONACME’s Dextrose DS is a sterile solution of Dextrose Anhydrous. It is mainly used to replace water deficiency and should be given alone when there is no significant loss of electrolytes.COMPOSITIONEach 100 ml of solution contains Dextrose Anhydrous BP 10 gm.INDICATIONSDextrose is administered in the treatment of carbohydrate and fluid depletions. It is mainly used to replace water deficiency and should be given alone when there is no significant loss of electrolytes. Water depletion (dehydration) tends to occur when these losses are not matched by a comparable intake, as for example may occur in coma or dysphagia or in the aged person who may not drink water in sufficient amount on their own initiative. It provides a readily metabolizable nutrient.DOSAGE AND ADMINISTRATIONThe dose of Dextrose infusion is variable. It is dependent on individual patient requirements. For 10% dextrose solution, the dose frequently ranges from 500 to 1000 ml. The maximum rate of infusion that will not cause glycosuria is 0.5 g/kg/hr...
Tk.105.80/=
Acme's Hartmann Solution IV Infusion 1000 ml bag
Acme's Hartmann Solution IV Infusion 1000 ml bagDESCRIPTIONACME’s Hartmann Solution is a sterile solution of Sodium Chloride, Potassium Chloride, Calcium Chloride and Sodium Lactate.COMPOSITIONEach 100ml of ACME’s Hartmann Solution contains Sodium Chloride BP 0.6 g, Potassium Chloride BP 0.04 g, Calcium Chloride BP 0.027 g and Sodium Lactate 50% solution USP equivalent to 0.32 g of Sodium Lactate. The solution contains per litre Sodium 131 mmol, Potassium 5 mmol, Calcium 2 mmol, Bicarbonate (as lactate) 29 mmol, and Chloride 111 mmol.INDICATIONSACME’s Hartmann Solution is used to treat hypovolemia caused by surgery, hemorrhage and trauma. Excessive sweating, severe diarrhoea or vomiting, excess loss of fluid by nephrotic kidneys, inadequate intake of fluid and electrolytes etc. that may lead to typical hypovolemic shock may be corrected with ACME’s Hartmann Solution. Severe plasma loss caused by intestinal obstruction, burns or other denuding conditions of the skin may be treated with ACME’s Hartmann Solution. ACME’s Hartmann Solution is mainly used as a fluid and electrolyte replenisher.DOSAGE AND ADMINISTRATIONThe volume and rate of infusion will depend upon the requirements of the patients and the judgement of the physician. The recommended flow rate is up to 100-drops/minute/70 kg body weight. ..
Tk.91.99/=
Acme's Milk of Magnesia 114ml Susp
Acme's Milk of Magnesia 114ml SuspDESCRIPTIONMagnesium Hydroxide is popularly known as Milk of Magnesia. It is a mildly acting antacid and laxative. It is poorly and slowly absorbed and acts by its osmotic properties in the luminal fluid which causes retention of fluid in the bowel. It is useful for emptying the bowel prior to surgical, radiological and colonoscopic procedures and can help to eliminate parasites following appropriate therapy and toxic material in some cases of poisoning. Magnesium Hydroxide is converted into Magnesium Chloride in the stomach without forming carbon dioxide.COMPOSITONEach 5 ml suspension contains Magnesium Hydroxide BP 400 mg.INDICATIONSACME'S MILK OF MAGNESIA is used in constipation, heart burn, gas and nausea. It is also indicated in acute and long acting constipation due to hyper acidity and peptic ulcer or stomatitis.DOSAGE AND ADMINISTRATIONAs Laxative:Adults: 2-4 Tablespoonful with a full glass of water.Children:6-11 years : 1-2 Tablespoonful with a full glass of water2-5 years : 1-3 Teaspoonful with a full glass of waterAs Antacid:Adults: 1-3 teaspoonful (5 to 15 ml) up to 4 times daily with water.Children:1-3 years : ¼ teaspoonful3-6 years : ¼-½ teaspoonful6-12 years : ½-1 teaspoonfulOR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSMagnesium Hydroxide in common with other magnesium salts may cause diarrhoea.CONTRAINDICATIONSMagnesium Hydroxide should not be administered where use of laxative is contraindicated. Long term treatment of Magnesium Hydroxide is contraindicated in patients with renal failure.PRECAUTIONSThe drug should be avoided if possible in patients with renal and hepatic failure and in those with heart block and myocardial disease. The drug may be used cautiously in pregnancy.DRUG INTERACTIONSMagnesium hydroxide can decrease the absorption of other drugs such as, digoxin, mycophenolate, phosphate supplements (e.g., potassium phosphate), tetracycline antibiotics, certain azole antifungals (ketoconazole, itraconazole), and quinolone antibiotics (e.g., ciprofloxacin, levofloxacin).SUPPLYSuspension: Each bottle contains 114 ml of suspension...
Tk.60.18/=
Acmecilin 100 ml Suspension
Acmecilin 100 ml SuspensionInteractionMay reduce the efficacy of oral contraceptives. May alter INR while on warfarin and phenindione. May reduce the efficacy of oral typhoid vaccines. May reduce the excretion of methotrexate. Reduced excretion with probenecid and sulfinpyrazone, resulting to increased risk of toxicity. Allopurinol increases ampicillin-induced skin reactions. Reduced absorption with chloroquine. Bacteriostatic antibacterials (e.g. erythromycin, chloramphenicol, tetracycline) may interfere with the bactericidal action of ampicillin.ContraindicationsHypersensitivity to ampicillin and other penicillins.PharmacologyAmpicillin inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin-binding proteins (PBPs) which in turn inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.Side EffectsNausea, vomiting, diarrhoea, erythematous maculo-papular rashes, sore mouth, black/hairy tongue, rash, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, fever, joint pains, serum sickness-like symptoms, haemolytic anaemia, thrombocytopenia, leucopenia, neutropenia, coagulation disorders, prolonged bleeding time and prothrombin time, CNS toxicity (e.g. convulsions); paraesthesia, nephropathy, interstitial nephritis, hepatitis, cholestatic jaundice, moderate and transient increase in transaminases, Anaphylaxis, Clostridium difficile-associated diarrhoea (CDAD).PrecautionsPatient with history of β-lactam allergy. During renal impairment, Pregnancy and lactation.Overdose EffectsSymptoms: Nausea, vomiting and diarrhoea.Management: Symptomatic and supportive treatment. May be removed from the circulation by haemodialysis...
Tk.39.71/=
Acmecilin 250 mg Capsule
Acmecilin 250 mg CapsuleInteractionMay reduce the efficacy of oral contraceptives. May alter INR while on warfarin and phenindione. May reduce the efficacy of oral typhoid vaccines. May reduce the excretion of methotrexate. Reduced excretion with probenecid and sulfinpyrazone, resulting to increased risk of toxicity. Allopurinol increases ampicillin-induced skin reactions. Reduced absorption with chloroquine. Bacteriostatic antibacterials (e.g. erythromycin, chloramphenicol, tetracycline) may interfere with the bactericidal action of ampicillin.ContraindicationsHypersensitivity to ampicillin and other penicillins.PharmacologyAmpicillin inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin-binding proteins (PBPs) which in turn inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.Side EffectsNausea, vomiting, diarrhoea, erythematous maculo-papular rashes, sore mouth, black/hairy tongue, rash, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, fever, joint pains, serum sickness-like symptoms, haemolytic anaemia, thrombocytopenia, leucopenia, neutropenia, coagulation disorders, prolonged bleeding time and prothrombin time, CNS toxicity (e.g. convulsions); paraesthesia, nephropathy, interstitial nephritis, hepatitis, cholestatic jaundice, moderate and transient increase in transaminases, Anaphylaxis, Clostridium difficile-associated diarrhoea (CDAD).PrecautionsPatient with history of β-lactam allergy. During renal impairment, Pregnancy and lactation.Overdose EffectsSymptoms: Nausea, vomiting and diarrhoea.Management: Symptomatic and supportive treatment. May be removed from the circulation by haemodialysis...
Tk.3.35/=
Acmecilin 250mg Injection
Acmecilin 250mgInteractionMay reduce the efficacy of oral contraceptives. May alter INR while on warfarin and phenindione. May reduce the efficacy of oral typhoid vaccines. May reduce the excretion of methotrexate. Reduced excretion with probenecid and sulfinpyrazone, resulting to increased risk of toxicity. Allopurinol increases ampicillin-induced skin reactions. Reduced absorption with chloroquine. Bacteriostatic antibacterials (e.g. erythromycin, chloramphenicol, tetracycline) may interfere with the bactericidal action of ampicillin.ContraindicationsHypersensitivity to ampicillin and other penicillins.PharmacologyAmpicillin inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin-binding proteins (PBPs) which in turn inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.Side EffectsNausea, vomiting, diarrhoea, erythematous maculo-papular rashes, sore mouth, black/hairy tongue, rash, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, fever, joint pains, serum sickness-like symptoms, haemolytic anaemia, thrombocytopenia, leucopenia, neutropenia, coagulation disorders, prolonged bleeding time and prothrombin time, CNS toxicity (e.g. convulsions); paraesthesia, nephropathy, interstitial nephritis, hepatitis, cholestatic jaundice, moderate and transient increase in transaminases, Anaphylaxis, Clostridium difficile-associated diarrhoea (CDAD).PrecautionsPatient with history of β-lactam allergy. During renal impairment, Pregnancy and lactation.Overdose EffectsSymptoms: Nausea, vomiting and diarrhoea.Management: Symptomatic and supportive treatment. May be removed from the circulation by haemodialysis...
Tk.20.00/=
Acmecilin 500mg Injection
Acmecilin 500InteractionMay reduce the efficacy of oral contraceptives. May alter INR while on warfarin and phenindione. May reduce the efficacy of oral typhoid vaccines. May reduce the excretion of methotrexate. Reduced excretion with probenecid and sulfinpyrazone, resulting to increased risk of toxicity. Allopurinol increases ampicillin-induced skin reactions. Reduced absorption with chloroquine. Bacteriostatic antibacterials (e.g. erythromycin, chloramphenicol, tetracycline) may interfere with the bactericidal action of ampicillin.ContraindicationsHypersensitivity to ampicillin and other penicillins.PharmacologyAmpicillin inhibits bacterial cell wall synthesis by binding to 1 or more of the penicillin-binding proteins (PBPs) which in turn inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.Side EffectsNausea, vomiting, diarrhoea, erythematous maculo-papular rashes, sore mouth, black/hairy tongue, rash, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, fever, joint pains, serum sickness-like symptoms, haemolytic anaemia, thrombocytopenia, leucopenia, neutropenia, coagulation disorders, prolonged bleeding time and prothrombin time, CNS toxicity (e.g. convulsions); paraesthesia, nephropathy, interstitial nephritis, hepatitis, cholestatic jaundice, moderate and transient increase in transaminases, Anaphylaxis, Clostridium difficile-associated diarrhoea (CDAD).PrecautionsPatient with history of β-lactam allergy. During renal impairment, Pregnancy and lactation.Overdose EffectsSymptoms: Nausea, vomiting and diarrhoea.Management: Symptomatic and supportive treatment. May be removed from the circulation by haemodialysis...
Tk.27.32/=
Acmegra 100 mg Tablet
Acmegra 100 mg TabletIndicationsSildenafil Citrate is indicated for the treatment of Erectile Dysfunction.PharmacologySildenafil Citrate belongs to a group of medicines called phosphodiesterase type-5 (PDE-5) inhibitors. It works by helping to relax the blood vessels of penis, allowing blood to flow into penis. The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. When sexual stimulation causes local release of NO, inhibition of PDE-5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.InteractionInhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the plasma concentrations of sildenafil. Symptomatic hypotension when used with α-blockers. Plasma concentrations are increased by ritonavir.ContraindicationsSildenafil was shown to potentiate the hypotensive effects of nitrates and its administration to patients who are using organic nitrates, either regularly and or intermittently, in any form is therefore contraindicated.Side EffectsLike all medicines, Sildenafil can cause side effects although not everybody gets them.The side effects reported in association with the use of Sildenafil are usually mild to moderate and of a short duration. All medicines including Sildenafil can cause allergic reactions.Contact with doctors immediately if experiences any of the following symptoms after taking Sildenafil: sudden wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat. Common side effect includes headache, facial flushing, indigestion, effects on vision, light sensitivity, blurred vision or reduced, stuffy nose and dizziness. Uncommon side effect includes vomiting, skin rash, bleeding at the back of the eye, red eyes, eye pain, double vision, abnormal sensation in the eye, irregular or rapid heartbeat, muscle pain, feeling sleepy, reduced sense of touch, vertigo, ringing in the ears, nausea, dry mouth, chest pain & feeling tired.Overdose EffectsIn studies with healthy volunteers of single doses up to 800 mg, adverse events were similar to those seen at lower doses but incidence rates and severities were increased. In cases of overdose, standard supportive measures should be adopted as required. Renal dialysis is not expected to accelerate clearance as sildenafil is highly bound to plasma proteins and it is not eliminated in the urine...
Tk.50.14/=
Acmegra 25 mg Tablet
Acmegra 25 mg TabletIndicationsSildenafil Citrate is indicated for the treatment of Erectile Dysfunction.PharmacologySildenafil Citrate belongs to a group of medicines called phosphodiesterase type-5 (PDE-5) inhibitors. It works by helping to relax the blood vessels of penis, allowing blood to flow into penis. The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. When sexual stimulation causes local release of NO, inhibition of PDE-5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.InteractionInhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the plasma concentrations of sildenafil. Symptomatic hypotension when used with α-blockers. Plasma concentrations are increased by ritonavir.ContraindicationsSildenafil was shown to potentiate the hypotensive effects of nitrates and its administration to patients who are using organic nitrates, either regularly and or intermittently, in any form is therefore contraindicated.Side EffectsLike all medicines, Sildenafil can cause side effects although not everybody gets them.The side effects reported in association with the use of Sildenafil are usually mild to moderate and of a short duration. All medicines including Sildenafil can cause allergic reactions.Contact with doctors immediately if experiences any of the following symptoms after taking Sildenafil: sudden wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat. Common side effect includes headache, facial flushing, indigestion, effects on vision, light sensitivity, blurred vision or reduced, stuffy nose and dizziness. Uncommon side effect includes vomiting, skin rash, bleeding at the back of the eye, red eyes, eye pain, double vision, abnormal sensation in the eye, irregular or rapid heartbeat, muscle pain, feeling sleepy, reduced sense of touch, vertigo, ringing in the ears, nausea, dry mouth, chest pain & feeling tired.Overdose EffectsIn studies with healthy volunteers of single doses up to 800 mg, adverse events were similar to those seen at lower doses but incidence rates and severities were increased. In cases of overdose, standard supportive measures should be adopted as required. Renal dialysis is not expected to accelerate clearance as sildenafil is highly bound to plasma proteins and it is not eliminated in the urine...
Tk.18.06/=
Acmegra 50 mg Tablet
Acmegra 50 mg TabletIndicationsSildenafil Citrate is indicated for the treatment of Erectile Dysfunction.PharmacologySildenafil Citrate belongs to a group of medicines called phosphodiesterase type-5 (PDE-5) inhibitors. It works by helping to relax the blood vessels of penis, allowing blood to flow into penis. The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. When sexual stimulation causes local release of NO, inhibition of PDE-5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.InteractionInhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the plasma concentrations of sildenafil. Symptomatic hypotension when used with α-blockers. Plasma concentrations are increased by ritonavir.ContraindicationsSildenafil was shown to potentiate the hypotensive effects of nitrates and its administration to patients who are using organic nitrates, either regularly and or intermittently, in any form is therefore contraindicated.Side EffectsLike all medicines, Sildenafil can cause side effects although not everybody gets them.The side effects reported in association with the use of Sildenafil are usually mild to moderate and of a short duration. All medicines including Sildenafil can cause allergic reactions.Contact with doctors immediately if experiences any of the following symptoms after taking Sildenafil: sudden wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat. Common side effect includes headache, facial flushing, indigestion, effects on vision, light sensitivity, blurred vision or reduced, stuffy nose and dizziness. Uncommon side effect includes vomiting, skin rash, bleeding at the back of the eye, red eyes, eye pain, double vision, abnormal sensation in the eye, irregular or rapid heartbeat, muscle pain, feeling sleepy, reduced sense of touch, vertigo, ringing in the ears, nausea, dry mouth, chest pain & feeling tired.Overdose EffectsIn studies with healthy volunteers of single doses up to 800 mg, adverse events were similar to those seen at lower doses but incidence rates and severities were increased. In cases of overdose, standard supportive measures should be adopted as required. Renal dialysis is not expected to accelerate clearance as sildenafil is highly bound to plasma proteins and it is not eliminated in the urine...
Tk.30.10/=
Adinir 300mg Capsule
Adinir 300IndicationsCefdinir is indicated for the treatment of Community Acquired Pneumonia, Acute Exacerbation of Chronic Bronchitis, Acute Maxillary Sinusitis, Pharyngitis, Tonsillitis, Uncomplicated Skin and Skin Structure, InfectionsInteractionAntacids: Cefdinir should be taken at least 2 hours interval of antacid administration.Iron supplement: Cefdinir should be taken at least 2 hours interval of iron supplement administration.Probencid: It inhibits the renal excretion of cefdinir.ContraindicationsCefdinir is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.Side EffectsCommon side effects are Diarrhea, Vaginal moniliasis, Nausea & Vomiting, Headache, Rash etc.Overdose EffectsSymptoms: Nausea, vomiting, epigastric distress, diarrhoea, convulsions.Management: Haemodialysis may be useful in the event of a serious toxic reaction particularly if renal function is compromised...
Tk.45.16/=
Adinir 60 ml Suspension
Adinir 60 ml SuspensionIndicationsCefdinir is indicated for the treatment of Community Acquired Pneumonia, Acute Exacerbation of Chronic Bronchitis, Acute Maxillary Sinusitis, Pharyngitis, Tonsillitis, Uncomplicated Skin and Skin Structure, InfectionsInteractionAntacids: Cefdinir should be taken at least 2 hours interval of antacid administration.Iron supplement: Cefdinir should be taken at least 2 hours interval of iron supplement administration.Probencid: It inhibits the renal excretion of cefdinir.ContraindicationsCefdinir is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.Side EffectsCommon side effects are Diarrhea, Vaginal moniliasis, Nausea & Vomiting, Headache, Rash etc.Overdose EffectsSymptoms: Nausea, vomiting, epigastric distress, diarrhoea, convulsions.Management: Haemodialysis may be useful in the event of a serious toxic reaction particularly if renal function is compromised...
Tk.175.66/=
Alclor 100 ml Suspension
Alclor 100 ml SuspensionDESCRIPTIONCefaclor is a second generation Cephalosporin antibiotic which has stability against β-lactamase inactivation and possesses a broad spectrum of activity. Cefaclor is active against the following organisms in vitro: Aerobes, Gram-positive: Alpha and beta haemolytic Streptococci, Staphylococci; including coagulase- positive, coagulase-negative and penicillinase-producing strains, Streptococcus pneumoniae, Streptococcus pyogenes (Group A β-haemolytic Streptococci)and Staphylococci. Aerobes, Gram-negative: Moraxella catarrhalis, Branhamella catarrhalis, Haemophilus influenzae, (including ampicillinresistant strains), Escherichia coli, Proteus mirabilis, Klebsiella sp., Citobacter diversus and Neisseria gonorrhea. Anaerobes: Propionibacteria acnes, Bacteroides sp. (excluding Bacteroides fragilis), Peptococci and Peptostreptococcus sp.COMPOSITIONCapsule Alclor 500: Each capsule contains Cefaclor monohydrate USP equivalent to Cefaclor 500 mg.Alclor powder for 100 ml suspension: Each 5 ml reconstituted suspension contains Cefaclor monohydrate USP equivalent to Cefaclor 125 mg.Alclor powder for 15 ml paediatric drops: Each 1.25 ml reconstituted paediatric drops contains Cefaclor monohydrate USP equivalent to Cefaclor 125 mg.INDICATIONAlclor (Cefaclor) is indicated for the treatment of the following infections due to susceptible micro-organisms: Respiratory tract infections including pneumonia, bronchitis, exacerbation of chronic bronchitis, pharyngitis, tonsillitis and as part of the management of sinusitis; Otitis media, Otitis media with effusion (OME); Skin and soft tissue infections; Urinary tract infections including pyelonephritis and cystitis; It is effective in both acute and chronic urinary tract infections.DOSAGE AND ADMINISTRATIONAlclor (Cefaclor) is administered orally. Adults: The usual adult dosage is 250 mg every eight hours. For more severe infections or those caused by less susceptible organisms, doses may be doubled.Alclor may be administered in the presence of impaired renal function. Under such conditions, dosage is usually unchanged. Patients undergoing haemodialysis: Haemodialysis shortens serum halflife by 25-30%. In patients undergoing regular haemodialysis, a loading dose of 250mg-1g administered prior to dialysis and a therapeutic dose of 250-500mg every six to eight hours maintained during interdialytic periods is recommended. The elderly: As for adults.Children: The usual recommended daily dosage for children is 20mg/kg/day in divided doses, every eight hours, as indicated. For bronchitis and pneumonia, the dosage is 20mg/kg/day in divided doses, administered 3 times daily. For otitis media and pharyngitis, the total daily dosage may be divided and administered every 12 hours. Safety and efficacy have not been established for use in infants aged less than one month.Alclor powder for Paediatric drops (125 mg/5 ml) In more serious infections, otitis media, sinusitis and infections caused by less susceptible organisms, 40mg/kg/day in divided doses is recommended, up to a daily maximum of 1g. In the treatment of beta-haemolytic streptococcal infections, therapy should be continued for at least 10 days.CONTRA-INDICATIONSAlclor is contraindicated to the patients who are hypersensitive to cephalosporin class of antibiotics.PRECAUTIONIf super infection occurs during therapy, appropriate measures should be taken. If an allergic reaction to Cefaclor occurs, the drug should be discontinued and then be treated with appropriate agents.SIDE EFFECTdiarrhoea (rarely antibiotic-associated colitis), nausea and vomiting, abdominal discomfort, headache; allergic reactions including rashes, pruritus, urticaria, serum sickness-like reactions with rashes, fever and arthralgia, and anaphylaxis; Stevens-Johnson syndrome, toxic epidermal necrolysis reported; disturbances in liver enzymes, transient hepatitis and cholestatic jaundice; other side-effects reported include eosinophilia and blood disorders (including thrombocytopenia, leucopenia, agranulocytosis, aplastic anaemia and hemolytic anemia); reversible interstitial nephritis, hyperactivity, nervousness, sleep disturbances, hallucinations, confusion, hypertonia, and dizziness.DRUG INTERACTIONThe nephrotoxicity of amino-glycoside antibiotics such as gentamicin and tobramicin may be enhanced by any Cephalosporin. Therefore, one should be cautious in concomitant use of these categories of drugs.USE IN PREGNANCY AND LACTATIONPregnancy: Not known to be harmful Breast-feeding: Present in milk in low concentration, but appropriate to use.OVER DOSAGESymptoms of nausea, vomiting, epigastric distress and diarrhoea would be anticipated. Treatment: Unless 5 times the normal total daily dose has been ingested, gastrointestinal decontamination will not be necessary. General management may consist of supportive therapy.SUPPLYCapsule: Each box contains 5 x 4 capsules in Alu-Alu Blister Strip.Powder for Suspension: Bottle containing dry powd..
Tk.190.58/=
Alclor 125 mg/1.25 ml Paediatric Drops 15 ml bottle
Alclor 125 mg/1.25 ml Paediatric Drops 15 ml bottleDESCRIPTIONCefaclor is a second generation Cephalosporin antibiotic which has stability against β-lactamase inactivation and possesses a broad spectrum of activity. Cefaclor is active against the following organisms in vitro: Aerobes, Gram-positive: Alpha and beta haemolytic Streptococci, Staphylococci; including coagulase- positive, coagulase-negative and penicillinase-producing strains, Streptococcus pneumoniae, Streptococcus pyogenes (Group A β-haemolytic Streptococci)and Staphylococci. Aerobes, Gram-negative: Moraxella catarrhalis, Branhamella catarrhalis, Haemophilus influenzae, (including ampicillinresistant strains), Escherichia coli, Proteus mirabilis, Klebsiella sp., Citobacter diversus and Neisseria gonorrhea. Anaerobes: Propionibacteria acnes, Bacteroides sp. (excluding Bacteroides fragilis), Peptococci and Peptostreptococcus sp.COMPOSITIONCapsule Alclor 500: Each capsule contains Cefaclor monohydrate USP equivalent to Cefaclor 500 mg.Alclor powder for 100 ml suspension: Each 5 ml reconstituted suspension contains Cefaclor monohydrate USP equivalent to Cefaclor 125 mg.Alclor powder for 15 ml paediatric drops: Each 1.25 ml reconstituted paediatric drops contains Cefaclor monohydrate USP equivalent to Cefaclor 125 mg.INDICATIONAlclor (Cefaclor) is indicated for the treatment of the following infections due to susceptible micro-organisms: Respiratory tract infections including pneumonia, bronchitis, exacerbation of chronic bronchitis, pharyngitis, tonsillitis and as part of the management of sinusitis; Otitis media, Otitis media with effusion (OME); Skin and soft tissue infections; Urinary tract infections including pyelonephritis and cystitis; It is effective in both acute and chronic urinary tract infections.DOSAGE AND ADMINISTRATIONAlclor (Cefaclor) is administered orally. Adults: The usual adult dosage is 250 mg every eight hours. For more severe infections or those caused by less susceptible organisms, doses may be doubled.Alclor may be administered in the presence of impaired renal function. Under such conditions, dosage is usually unchanged. Patients undergoing haemodialysis: Haemodialysis shortens serum halflife by 25-30%. In patients undergoing regular haemodialysis, a loading dose of 250mg-1g administered prior to dialysis and a therapeutic dose of 250-500mg every six to eight hours maintained during interdialytic periods is recommended. The elderly: As for adults.Children: The usual recommended daily dosage for children is 20mg/kg/day in divided doses, every eight hours, as indicated. For bronchitis and pneumonia, the dosage is 20mg/kg/day in divided doses, administered 3 times daily. For otitis media and pharyngitis, the total daily dosage may be divided and administered every 12 hours. Safety and efficacy have not been established for use in infants aged less than one month.Alclor powder for Paediatric drops (125 mg/5 ml) In more serious infections, otitis media, sinusitis and infections caused by less susceptible organisms, 40mg/kg/day in divided doses is recommended, up to a daily maximum of 1g. In the treatment of beta-haemolytic streptococcal infections, therapy should be continued for at least 10 days.CONTRA-INDICATIONSAlclor is contraindicated to the patients who are hypersensitive to cephalosporin class of antibiotics.PRECAUTIONIf super infection occurs during therapy, appropriate measures should be taken. If an allergic reaction to Cefaclor occurs, the drug should be discontinued and then be treated with appropriate agents.SIDE EFFECTdiarrhoea (rarely antibiotic-associated colitis), nausea and vomiting, abdominal discomfort, headache; allergic reactions including rashes, pruritus, urticaria, serum sickness-like reactions with rashes, fever and arthralgia, and anaphylaxis; Stevens-Johnson syndrome, toxic epidermal necrolysis reported; disturbances in liver enzymes, transient hepatitis and cholestatic jaundice; other side-effects reported include eosinophilia and blood disorders (including thrombocytopenia, leucopenia, agranulocytosis, aplastic anaemia and hemolytic anemia); reversible interstitial nephritis, hyperactivity, nervousness, sleep disturbances, hallucinations, confusion, hypertonia, and dizziness.DRUG INTERACTIONThe nephrotoxicity of amino-glycoside antibiotics such as gentamicin and tobramicin may be enhanced by any Cephalosporin. Therefore, one should be cautious in concomitant use of these categories of drugs.USE IN PREGNANCY AND LACTATIONPregnancy: Not known to be harmful Breast-feeding: Present in milk in low concentration, but appropriate to use.OVER DOSAGESymptoms of nausea, vomiting, epigastric distress and diarrhoea would be anticipated. Treatment: Unless 5 times the normal total daily dose has been ingested, gastrointestinal decontamination will not be necessary. General management may consist of supportive therapy.SUPPLYCapsule: Each box contains 5 x 4 capsules in Alu-Alu Blister Strip.Powder for Suspension:..
Tk.125.37/=
Alclor 500mg Capsule
Alclor 500mg CapsuleDESCRIPTIONCefaclor is a second generation Cephalosporin antibiotic which has stability against β-lactamase inactivation and possesses a broad spectrum of activity. Cefaclor is active against the following organisms in vitro: Aerobes, Gram-positive: Alpha and beta haemolytic Streptococci, Staphylococci; including coagulase- positive, coagulase-negative and penicillinase-producing strains, Streptococcus pneumoniae, Streptococcus pyogenes (Group A β-haemolytic Streptococci)and Staphylococci. Aerobes, Gram-negative: Moraxella catarrhalis, Branhamella catarrhalis, Haemophilus influenzae, (including ampicillinresistant strains), Escherichia coli, Proteus mirabilis, Klebsiella sp., Citobacter diversus and Neisseria gonorrhea. Anaerobes: Propionibacteria acnes, Bacteroides sp. (excluding Bacteroides fragilis), Peptococci and Peptostreptococcus sp.COMPOSITIONCapsule Alclor 500: Each capsule contains Cefaclor monohydrate USP equivalent to Cefaclor 500 mg.Alclor powder for 100 ml suspension: Each 5 ml reconstituted suspension contains Cefaclor monohydrate USP equivalent to Cefaclor 125 mg.Alclor powder for 15 ml paediatric drops: Each 1.25 ml reconstituted paediatric drops contains Cefaclor monohydrate USP equivalent to Cefaclor 125 mg.INDICATIONAlclor (Cefaclor) is indicated for the treatment of the following infections due to susceptible micro-organisms: Respiratory tract infections including pneumonia, bronchitis, exacerbation of chronic bronchitis, pharyngitis, tonsillitis and as part of the management of sinusitis; Otitis media, Otitis media with effusion (OME); Skin and soft tissue infections; Urinary tract infections including pyelonephritis and cystitis; It is effective in both acute and chronic urinary tract infections.DOSAGE AND ADMINISTRATIONAlclor (Cefaclor) is administered orally. Adults: The usual adult dosage is 250 mg every eight hours. For more severe infections or those caused by less susceptible organisms, doses may be doubled.Alclor may be administered in the presence of impaired renal function. Under such conditions, dosage is usually unchanged. Patients undergoing haemodialysis: Haemodialysis shortens serum halflife by 25-30%. In patients undergoing regular haemodialysis, a loading dose of 250mg-1g administered prior to dialysis and a therapeutic dose of 250-500mg every six to eight hours maintained during interdialytic periods is recommended. The elderly: As for adults.Children: The usual recommended daily dosage for children is 20mg/kg/day in divided doses, every eight hours, as indicated. For bronchitis and pneumonia, the dosage is 20mg/kg/day in divided doses, administered 3 times daily. For otitis media and pharyngitis, the total daily dosage may be divided and administered every 12 hours. Safety and efficacy have not been established for use in infants aged less than one month.Alclor powder for Paediatric drops (125 mg/5 ml) In more serious infections, otitis media, sinusitis and infections caused by less susceptible organisms, 40mg/kg/day in divided doses is recommended, up to a daily maximum of 1g. In the treatment of beta-haemolytic streptococcal infections, therapy should be continued for at least 10 days.CONTRA-INDICATIONSAlclor is contraindicated to the patients who are hypersensitive to cephalosporin class of antibiotics.PRECAUTIONIf super infection occurs during therapy, appropriate measures should be taken. If an allergic reaction to Cefaclor occurs, the drug should be discontinued and then be treated with appropriate agents.SIDE EFFECTdiarrhoea (rarely antibiotic-associated colitis), nausea and vomiting, abdominal discomfort, headache; allergic reactions including rashes, pruritus, urticaria, serum sickness-like reactions with rashes, fever and arthralgia, and anaphylaxis; Stevens-Johnson syndrome, toxic epidermal necrolysis reported; disturbances in liver enzymes, transient hepatitis and cholestatic jaundice; other side-effects reported include eosinophilia and blood disorders (including thrombocytopenia, leucopenia, agranulocytosis, aplastic anaemia and hemolytic anemia); reversible interstitial nephritis, hyperactivity, nervousness, sleep disturbances, hallucinations, confusion, hypertonia, and dizziness.DRUG INTERACTIONThe nephrotoxicity of amino-glycoside antibiotics such as gentamicin and tobramicin may be enhanced by any Cephalosporin. Therefore, one should be cautious in concomitant use of these categories of drugs.USE IN PREGNANCY AND LACTATIONPregnancy: Not known to be harmful Breast-feeding: Present in milk in low concentration, but appropriate to use.OVER DOSAGESymptoms of nausea, vomiting, epigastric distress and diarrhoea would be anticipated. Treatment: Unless 5 times the normal total daily dose has been ingested, gastrointestinal decontamination will not be necessary. General management may consist of supportive therapy.SUPPLYCapsule: Each box contains 5 x 4 capsules in Alu-Alu Blister Strip.Powder for Suspension: Bottle containing dry powder t..
Tk.40.12/=
Alercon 5 ml E/D
Alercon 5 ml E/DDESCRIPTIONALERCON Eye Drops is a sterile ophthalmic solution, a relatively selective H1- receptor antagonist.COMPOSITIONAlercon : Each ml contains Olopatadine Hydrochloride USP equivalent to Olopatadine 1 mg.Alercon DS : Each ml contains Olopatadine Hydrochloride USP equivalent to Olopatadine 2 mg.INDICATIONSALERCON Eye Drops is indicated for the treatment of the signs and symptoms of allergic conjunctivitis.DOSAGE AND ADMINISTRATIONAlercon : The recommended dose is 1-2 drops in each affected eye two times per day. Maximum duration of treatment is four months.Alercon DS : The recommended dose is one drop in each affected eye once daily.SIDE EFFECTSLocal irritation; less commonly keratitis, dry eye, local oedema, photophobia, headache, asthenia, dizziness; dry nose are reported.CONTRAINDICATIONALERCON Eye Drops is contraindicated in patients with hypersensitivity to Olopatadine or any other component of the preparation.PRECAUTIONALERCON DS (Olopatadine Hydrochloride) ophthalmic solution is for topical use only and not for injection or oral use. Patients should be advised not to wear contact lens if their eye is red. ALERCON DS (Olopatadine Hydrochloride) ophthalmic solution should not be used to treat contact lens related irritation. Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instilling ALERCON DS (Olopatadine Hydrochloride) ophthalmic solution before they insert their contact lenses.USE IN PREGNANCY & LACTATIONPregnancy : Pregnancy category C.Lactation: Caution should be exercised when Olopatadine Hydrochloride eye drops is administered to a nursing mother.USE IN CHILDRENSafety and effectiveness in paediatric patients below the age of 3 years have not been established.SUPPLYAlercon : Each plastic dropper bottle contains 5 ml sterile eye drops.Alercon DS: Each plastic dropper bottle contains 5 ml sterile eye drops..
Tk.100.30/=
Alercon 600 mcg nasal spray
Alercon 600 mcg nasal sprayDESCRIPTIONALERCON Eye Drops is a sterile ophthalmic solution, a relatively selective H1- receptor antagonist.COMPOSITIONAlercon : Each ml contains Olopatadine Hydrochloride USP equivalent to Olopatadine 1 mg.Alercon DS : Each ml contains Olopatadine Hydrochloride USP equivalent to Olopatadine 2 mg.INDICATIONSALERCON Eye Drops is indicated for the treatment of the signs and symptoms of allergic conjunctivitis.DOSAGE AND ADMINISTRATIONAlercon : The recommended dose is 1-2 drops in each affected eye two times per day. Maximum duration of treatment is four months.Alercon DS : The recommended dose is one drop in each affected eye once daily.SIDE EFFECTSLocal irritation; less commonly keratitis, dry eye, local oedema, photophobia, headache, asthenia, dizziness; dry nose are reported.CONTRAINDICATIONALERCON Eye Drops is contraindicated in patients with hypersensitivity to Olopatadine or any other component of the preparation.PRECAUTIONALERCON DS (Olopatadine Hydrochloride) ophthalmic solution is for topical use only and not for injection or oral use. Patients should be advised not to wear contact lens if their eye is red. ALERCON DS (Olopatadine Hydrochloride) ophthalmic solution should not be used to treat contact lens related irritation. Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instilling ALERCON DS (Olopatadine Hydrochloride) ophthalmic solution before they insert their contact lenses.USE IN PREGNANCY & LACTATIONPregnancy : Pregnancy category C.Lactation: Caution should be exercised when Olopatadine Hydrochloride eye drops is administered to a nursing mother.USE IN CHILDRENSafety and effectiveness in paediatric patients below the age of 3 years have not been established...
Tk.401.20/=
Alercon DS 0.2% Eye Drops 5 ml drop
Alercon DS 0.2% Eye Drops 5 ml dropDESCRIPTIONALERCON Eye Drops is a sterile ophthalmic solution, a relatively selective H1- receptor antagonist.COMPOSITIONAlercon : Each ml contains Olopatadine Hydrochloride USP equivalent to Olopatadine 1 mg.Alercon DS : Each ml contains Olopatadine Hydrochloride USP equivalent to Olopatadine 2 mg.INDICATIONSALERCON Eye Drops is indicated for the treatment of the signs and symptoms of allergic conjunctivitis.DOSAGE AND ADMINISTRATIONAlercon : The recommended dose is 1-2 drops in each affected eye two times per day. Maximum duration of treatment is four months.Alercon DS : The recommended dose is one drop in each affected eye once daily.SIDE EFFECTSLocal irritation; less commonly keratitis, dry eye, local oedema, photophobia, headache, asthenia, dizziness; dry nose are reported.CONTRAINDICATIONALERCON Eye Drops is contraindicated in patients with hypersensitivity to Olopatadine or any other component of the preparation.PRECAUTIONALERCON DS (Olopatadine Hydrochloride) ophthalmic solution is for topical use only and not for injection or oral use. Patients should be advised not to wear contact lens if their eye is red. ALERCON DS (Olopatadine Hydrochloride) ophthalmic solution should not be used to treat contact lens related irritation. Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instilling ALERCON DS (Olopatadine Hydrochloride) ophthalmic solution before they insert their contact lenses.USE IN PREGNANCY & LACTATIONPregnancy : Pregnancy category C.Lactation: Caution should be exercised when Olopatadine Hydrochloride eye drops is administered to a nursing mother.USE IN CHILDRENSafety and effectiveness in paediatric patients below the age of 3 years have not been established.SUPPLYAlercon : Each plastic dropper bottle contains 5 ml sterile eye drops.Alercon DS: Each plastic dropper bottle contains 5 ml sterile eye drops..
Tk.150.44/=
