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Adiponil Capsule

Adiponil Capsule

IndicationsAdiponil is indicated for long term treatment of significantly obese patients, including patients with risk factors associated with obesity, in conjunction with a mildly hypocaloric diet. Adiponil is also indicated in long term weight control such as weight loss, weight maintenance and prevention of weight regainDescriptionsAdiponil is a potent, specific and reversible long acting inhibitor of gastrointestinal lipases for obesity management that acts by inhibiting the absorption of dietary fat. It exerts its therapeutic activity in the human stomach and small intestine by forming a covalent bond with the active serine residue of the active site of gastric and pancreatic lipases. The inactivated enzymes are thus unable to hydrolyze the dietary fat in the form of triglycerides, into absorbable free fatty acids and monoglycerides. As undigested triglycerides are not absorbed, the resulting calorie deficit has a positive effect on weight control. Systemic absorption of the drug is therefore not needed for activity. At the recommended therapeutic dose of 120 mg three times a day, Orlistat inhibits dietary fat absorption by approximately 30 %.Dosage & AdministrationThe recommended dose of Adiponil is one 120 mg capsule three times a day with each main meal (during or upto 1 hour after the meal).Side EffectsGenerally Adiponil is well tolerated. However few side effects including oily spotting, flattus with discharge, faecal urgeney, oily evaculation, increased defaecation may be seen after administration of orlistatPrecautionsPatients should be advised to adhere to dietary guidelines. gastrointestinal events may increase when orlistat is taken with a diet high in fat (>30% of calories from fat). The daily intake of fat should be distributed over three main meals. If a meal is missed, the dose of orlistat may be omitted.ContraindicationsOrlistat is contraindicated in patients with chronic malabsorption syndrome, cholestasis and in patients with known hypersensitivity to orlistat or to any components of this product.Use in Pregnancy & LactationThere are no adequate and well controlled studies of orlistat in pregnant women. Orlistat is not recommended for use during pregnancy. It is not known if orlistat is secreted in human breast milk. Orlistat should not be taken by nursing women.OverdoseSingle doses of 800 mg and multiple doses of up to 400 mg three times a day for 15 days have been studied in normal weight and obese subjects without significant adverse findings. If a significant overdose of orlistat occur, it is recommended that the patient be observed for 24 hours. Based on human and animal studies, any systemic effects attributable to the lipase inhibiting properties of orlistat should be rapidly reversibleCommercial PackagingAdiponil capsule: Each box contains 1 blister strip of 10 capsules..

Tk.40.00/=

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Adora 1000 Tablet

Adora 1000 Tablet

Adora 1000 TabletAdora 500 Capsule: Each capsule contains Cefadroxil Monohydrate USP equivalent to Cefadroxil 500 mg.Adora Powder for Suspension: When reconstituted each 5 ml of suspension contains Cefadroxil Monohydrate USP equivalent to Cefadroxil 125 mg.Adora Powder for Paediatric Drops: When reconstituted each 1.25 ml contains Cefadroxil Monohydrate USP equivalent to Cefadroxil 125 mg.DescriptionAdora (Cefadroxil Monohydrate) is an acid-stable semi-synthetic oral antibiotic in the cephalosporin family of drugs. Cefadroxil acts by preventing bacteria from forming protective cell wall necessary for survival. It has superior pharmacokinetic profile over all first generation cephalosporins.IndicationsAdora (Cefadroxil Monohydrate) is indicated for the treatment of patients with infection caused by susceptible strains of the designated organisms in the following diseases:*Upper respiratory tract infections caused by Streptococcus pyogenes (Group A beta-hemolytic Streptococci) and Streptococcus pneumoniae.* Urinary tract infections caused by E. coli, Proteus mirabilis, and Klebsiella species.* Skin and soft tissue infections caused by Staphylococci (including penicillinase producing strains) and Streptococci.Dosage & AdministrationThe bioavailability and consequent chemotherapeutic effects of Cefadroxil are unaffected by foods. It may, therefore, be taken with meals or on an empty stomach. Administration with food may be helpful in diminishing potential gastrointestinal complaints occasionally associated with oral cephalosporin therapy.IndicationAdult (dose)Children (Dose)Upper respiratory tract Infections1 gm per day in single (q.d.) or divided doses (b.i.d.) for 10 days 12 hourly30 mg/kg/day in a single or in equally divided doses every 12 hoursUrinary Tract Infections1 or 2 gm per day in single (q.d.) or divided doses (b.i.d.)30 mg/kg/day in equally divided doses every 12 hoursFor all other UTIs2 gm per day in divided doses (b.i.d)30 mg/kg/day in equally divided doses every 12 hoursSkin & soft tissue Infections1 gm per day in single (q.d.) or divided doses (b.i.d.)30 mg/kg/day in equally divided doses every 12 hoursProphylaxis against bacterial endocarditis2 gm 1 hour prior to the procedure50 mg/kg 1 hour prior to the procedureSide EffectsGenerally cefadroxil is well tolerated. However, the most commonly reported side effects are gastrointestinal disturbances and hypersensitivity phenomena. Side effects including nausea, vomiting, diarrhoea, dyspepsia, abdominal discomfort, fever, dizziness, headache, arthralgia may also occur.PrecautionsN/AUse in Pregnancy & LactationCefadroxil (Adora) is widely used as a first-line oral antibiotic for the treatment of uncomplicated urinary tract infections in pregnant women.Drug InteractionThere is no known clinically important drug interactions with Cefadroxil.Over DoseIf amounts >250 mg/kg is ingested, gastric lavage or simulation of vomiting is appropriate.Commercial PackAdora 500 mg Capsule : Box containing 5 Alu-Alu blister strips of 4 capsules.Adora Powder for Suspension : Bottle containing powder to produce 100 ml suspension when reconstituted.Adora Powder for Suspension : Bottle containing powder to produce 60 ml suspension when reconstituted.Adora Powder for Paediatric Drops: Bottle containing powder for preparation of 15 ml suspension.OthersDirection for Reconstitution of suspensionFor 100 ml suspension and 100 ml DS suspension: Add 65 ml (13 measuring spoonful) of boiled and cooled water to the dry mixture in the bottle. For ease of preparation add water to the bottle in two portions. Shake well after each addition until all the powder is in suspension.For 60 ml suspension: Add 40 ml (8 measuring spoonful) of boiled and cooled water to the dry mixture in the bottle. For ease of preparation add water to the bottle in two portions. Shake well after each addition until all the powder is in suspension.Paediatric Drops: Add 10 ml (2 measuring spoonful) to the bottle and shake vigorously.Note: Shake both oral suspension and paediatric drops well before each use. Keep the bottle tightly closed. The reconstituted suspension should be stored in a cool and dry place, preferably in refrigerator and unused portion should be discarded after 14 days...

Tk.32.00/=

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Adora 500 Capsule

Adora 500 Capsule

DescriptionAdora (Cefadroxil Monohydrate) is an acid-stable semi-synthetic oral antibiotic in the cephalosporin family of drugs. Cefadroxil acts by preventing bacteria from forming protective cell wall necessary for survival. It has superior pharmacokinetic profile over all first generation cephalosporins.IndicationsAdora (Cefadroxil Monohydrate) is indicated for the treatment of patients with infection caused by susceptible strains of the designated organisms in the following diseases:*Upper respiratory tract infections caused by Streptococcus pyogenes (Group A beta-hemolytic Streptococci) and Streptococcus pneumoniae.* Urinary tract infections caused by E. coli, Proteus mirabilis, and Klebsiella species.* Skin and soft tissue infections caused by Staphylococci (including penicillinase producing strains) and Streptococci.Dosage & AdministrationThe bioavailability and consequent chemotherapeutic effects of Cefadroxil are unaffected by foods. It may, therefore, be taken with meals or on an empty stomach. Administration with food may be helpful in diminishing potential gastrointestinal complaints occasionally associated with oral cephalosporin therapy.IndicationAdult (dose)Children (Dose)Upper respiratory tract Infections1 gm per day in single (q.d.) or divided doses (b.i.d.) for 10 days 12 hourly30 mg/kg/day in a single or in equally divided doses every 12 hoursUrinary Tract Infections1 or 2 gm per day in single (q.d.) or divided doses (b.i.d.)30 mg/kg/day in equally divided doses every 12 hoursFor all other UTIs2 gm per day in divided doses (b.i.d)30 mg/kg/day in equally divided doses every 12 hoursSkin & soft tissue Infections1 gm per day in single (q.d.) or divided doses (b.i.d.)30 mg/kg/day in equally divided doses every 12 hoursProphylaxis against bacterial endocarditis2 gm 1 hour prior to the procedure50 mg/kg 1 hour prior to the procedureSide EffectsGenerally cefadroxil is well tolerated. However, the most commonly reported side effects are gastrointestinal disturbances and hypersensitivity phenomena. Side effects including nausea, vomiting, diarrhoea, dyspepsia, abdominal discomfort, fever, dizziness, headache, arthralgia may also occur.PrecautionsN/AUse in Pregnancy & LactationCefadroxil (Adora) is widely used as a first-line oral antibiotic for the treatment of uncomplicated urinary tract infections in pregnant women.Drug InteractionThere is no known clinically important drug interactions with Cefadroxil.Over DoseIf amounts >250 mg/kg is ingested, gastric lavage or simulation of vomiting is appropriate...

Tk.18.00/=

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Adora Suspension

Adora Suspension

Adora Suspension DescriptionAdora (Cefadroxil Monohydrate) is an acid-stable semi-synthetic oral antibiotic in the cephalosporin family of drugs. Cefadroxil acts by preventing bacteria from forming protective cell wall necessary for survival. It has superior pharmacokinetic profile over all first generation cephalosporins.IndicationsAdora (Cefadroxil Monohydrate) is indicated for the treatment of patients with infection caused by susceptible strains of the designated organisms in the following diseases:*Upper respiratory tract infections caused by Streptococcus pyogenes (Group A beta-hemolytic Streptococci) and Streptococcus pneumoniae.* Urinary tract infections caused by E. coli, Proteus mirabilis, and Klebsiella species.* Skin and soft tissue infections caused by Staphylococci (including penicillinase producing strains) and Streptococci.Dosage & AdministrationThe bioavailability and consequent chemotherapeutic effects of Cefadroxil are unaffected by foods. It may, therefore, be taken with meals or on an empty stomach. Administration with food may be helpful in diminishing potential gastrointestinal complaints occasionally associated with oral cephalosporin therapy.IndicationAdult (dose)Children (Dose)Upper respiratory tract Infections1 gm per day in single (q.d.) or divided doses (b.i.d.) for 10 days 12 hourly30 mg/kg/day in a single or in equally divided doses every 12 hoursUrinary Tract Infections1 or 2 gm per day in single (q.d.) or divided doses (b.i.d.)30 mg/kg/day in equally divided doses every 12 hoursFor all other UTIs2 gm per day in divided doses (b.i.d)30 mg/kg/day in equally divided doses every 12 hoursSkin & soft tissue Infections1 gm per day in single (q.d.) or divided doses (b.i.d.)30 mg/kg/day in equally divided doses every 12 hoursProphylaxis against bacterial endocarditis2 gm 1 hour prior to the procedure50 mg/kg 1 hour prior to the procedureSide EffectsGenerally cefadroxil is well tolerated. However, the most commonly reported side effects are gastrointestinal disturbances and hypersensitivity phenomena. Side effects including nausea, vomiting, diarrhoea, dyspepsia, abdominal discomfort, fever, dizziness, headache, arthralgia may also occur.PrecautionsN/AUse in Pregnancy & LactationCefadroxil (Adora) is widely used as a first-line oral antibiotic for the treatment of uncomplicated urinary tract infections in pregnant women.Drug InteractionThere is no known clinically important drug interactions with Cefadroxil.Over DoseIf amounts >250 mg/kg is ingested, gastric lavage or simulation of vomiting is appropriate...

Tk.60.00/=

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Adora Suspension  100 ml

Adora Suspension 100 ml

Adora SuspDescriptionAdora (Cefadroxil Monohydrate) is an acid-stable semi-synthetic oral antibiotic in the cephalosporin family of drugs. Cefadroxil acts by preventing bacteria from forming protective cell wall necessary for survival. It has superior pharmacokinetic profile over all first generation cephalosporins.IndicationsAdora (Cefadroxil Monohydrate) is indicated for the treatment of patients with infection caused by susceptible strains of the designated organisms in the following diseases:*Upper respiratory tract infections caused by Streptococcus pyogenes (Group A beta-hemolytic Streptococci) and Streptococcus pneumoniae.* Urinary tract infections caused by E. coli, Proteus mirabilis, and Klebsiella species.* Skin and soft tissue infections caused by Staphylococci (including penicillinase producing strains) and Streptococci.Dosage & AdministrationThe bioavailability and consequent chemotherapeutic effects of Cefadroxil are unaffected by foods. It may, therefore, be taken with meals or on an empty stomach. Administration with food may be helpful in diminishing potential gastrointestinal complaints occasionally associated with oral cephalosporin therapy.IndicationAdult (dose)Children (Dose)Upper respiratory tract Infections1 gm per day in single (q.d.) or divided doses (b.i.d.) for 10 days 12 hourly30 mg/kg/day in a single or in equally divided doses every 12 hoursUrinary Tract Infections1 or 2 gm per day in single (q.d.) or divided doses (b.i.d.)30 mg/kg/day in equally divided doses every 12 hoursFor all other UTIs2 gm per day in divided doses (b.i.d)30 mg/kg/day in equally divided doses every 12 hoursSkin & soft tissue Infections1 gm per day in single (q.d.) or divided doses (b.i.d.)30 mg/kg/day in equally divided doses every 12 hoursProphylaxis against bacterial endocarditis2 gm 1 hour prior to the procedure50 mg/kg 1 hour prior to the procedureSide EffectsGenerally cefadroxil is well tolerated. However, the most commonly reported side effects are gastrointestinal disturbances and hypersensitivity phenomena. Side effects including nausea, vomiting, diarrhoea, dyspepsia, abdominal discomfort, fever, dizziness, headache, arthralgia may also occur.PrecautionsN/AUse in Pregnancy & LactationCefadroxil (Adora) is widely used as a first-line oral antibiotic for the treatment of uncomplicated urinary tract infections in pregnant women.Drug InteractionThere is no known clinically important drug interactions with Cefadroxil.Over DoseIf amounts >250 mg/kg is ingested, gastric lavage or simulation of vomiting is appropriate...

Tk.70.00/=

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Adrinor 1mg 1 ml Injection

Adrinor 1mg 1 ml Injection

IndicationsAdjunctive use in the management of cardiac arrest. It is used in cardiopulmonary resuscitation. Intracardiac puncture and intramyocardial injection of adrenaline may be effective when external cardiac compression and attempts to restore the circulation by electrical defibrillation or use of a pacemaker fail. Adrenaline is a drug that leads to increased blood pressure, increased heart rate, increased air entry, increased blood glucose, stimulates cardiac activity and reduces allergic reactions by reducing inflammatory response caused by histamine. Due to these properties, it is used for the treatment of allergic and anaphylactic reactions. Adrenaline is the favored treatment for anaphylactic shock and should be administered immediately if a person begins exhibiting severe allergic reactions. Adrenaline is also used in life threatening asthma when failing ventilation and continued deterioration despite nebulizer therapy.DescriptionsAdrenaline is a direct-acting sympathomimetic agent exerting its effect on alpha and beta-adrenoceptors. The overall effect of adrenaline depends on the dose, and may be complicated by the homeostatic reflex responses. In resuscitation procedures it is used to increase the efficacy of basic life support. It is a positive cardiac inotrope. Major effects are increased systolic blood pressure by arterioral and venous vasoconstriction (alpha1 effects), reduced diastolic pressure, tachycardia and hyperglycaemia. Adrenaline is rapid in onset and with short duration. After IV infusion the half-life is approximately 5-10 minutes. It is rapidly distributed to the heart, spleen, several glandular tissues and adrenergic nerves. Adrenaline is rapidly metabolised in the liver and tissues by oxidative de-amination and O-methylation followed by reduction or by conjugation with glucuronic acid or sulphate. Up to 90% of the IV dose is excreted in the urine as metabolites. It is approximately 50% bound to plasma proteins.Dosage & AdministrationCardiac arrest: 1. Intravenous injection: 1 mg injection repeated every 2-3 minutes as necessary. 2. Endotracheal: 2-3 mg via an endotracheal tube, repeated as necessary. 3. Intracardiac injection: 0.1 to 1 mg, direct into the atrium of the heart. 4. Intraspinal use: Usual dose is 0.2 to 0.4 mg added to anesthetic spinal fluid mixture (to prolong anesthetic action by limiting absorption). Anaphylaxis, asthma or severe bronchospasm: Adult dose is 0.25 - 0.5 mg. It may be repeated at 5 minutes intervals until perfusion and respiratory status normalizes. In case of dose dilution: 1 mg of Adrenaline to be diluted in 9 ml Normal Saline. Children: Intravenous injection: Initially 10 mcg/kg body weight, not to exceed 250 mcg. May be repeated every 3-5 minutes if necessary. Subsequent doses should be 100 mcg/kg.Side EffectsAnxiety, restlessness, dizziness, headache, palpitations, rapid pulse, tremors, weakness and coldness of the extremities may be reported even with small doses and especially when given in conjunction with local anaesthetics.PrecautionsThe solution should not be used if it is pinkish or darker than slightly yellow or if it contains a precipitate. Adrenaline is readily destroyed by alkalies and oxidizing agents. In the latter category are Oxygen, Chlorine, Iodine, Permanganates, Chromates, Nitrites and salts of easily reducible metals, especially Iron. Adrenaline should not be mixed with Sodium bicarbonate; the solution is oxidised to adrenochrome and then forms polymers. Special warnings and precautions for use Administer slowly with caution to elderly patients and to patients with ischemic heart disease, hypertension, diabetes mellitus, hyperthyroidism or psychoneurosis. Use with extreme caution in patients with long-standing bronchial asthma and emphysema who have developed degenerative heart disease. Anginal pain may be induced when coronary insufficiency is present.ContraindicationsHypertension, arteriosclerosis, coronary disease and hyperthyroidism. Not to be given to patients taking monoamine oxidase inhibitors.Use in Pregnancy & LactationPregnancy Category C. It crosses the placenta and is excreted in breast milk. Adrenaline should only be used in pregnancy if the potential benefits outweigh the risks to the fetus. Lactating mothers: It is excreted in breast milk and therefore Adrenaline is not recommended for use during lactation because of the risk of adverse effects of infants.Drug InteractionUse of Adrenaline with excessive doses of digitalis, mercurial diuretics or other drugs that sensitize the heart to arrhythmias is not recommended. The adverse effects of Adrenaline may be potentiated by tricyclic antidepressants; certain antihistamines; e.g, Diphenhydramine, Tripelennamine, Chlorpheniramine and L-thyroxine Sodium.OverdoseSymptoms: Cardiac arrhythmia leading to ventricular fibrillation, severe hypertension leading to pulmonary edema and cerebral hemorrhage. Treatmen..

Tk.25.00/=

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Alestor 5 mg Tab

Alestor 5 mg Tab

Alestor 5 mg TabPresentationAlestor: Each tablet contains Allylestrenol INN 5mg.DescriptionAllylestrenol is an orally active gestagen. Allylestrenol has a pronounced pregnancy maintaining action in castrated animals without producing hormonal side-effects. In the human, premature termination of pregnancy often follows a fall in the levels of placental hormones. Alestor has been shown to stimulate the placental progesterone production in vitro & to promote the secretion of placental hormones (human chorionic gonadotrophin, human placental lactogen, oestrogens and progesterone) and oxytocinase in patients with pregnancy at risk. In aggrement to this the trophoblastic layers of the placenta show histological signs of activation. Clinical studies have indicated that Alestor is an effective & safe pregnancy preparation. Administration of Alestor in combination with bed rest can remove or prevent the threat of abortion in early pregnancy or stop threatened premature labor.Dosage & AdministrationAlestor should be taken orally. The dose of the drug depends on the indication.Intra Uterine Growth Retardation [IUGR]: 1 tablet three times a day at least two months. Reduce the dose if symptoms improve.Threatened Abortion: 1 tablet thrice daily for 5-7 days. The treatment period may be extended depending on necessity. After symptoms disappear, the dosage should be gradually reduced.Habitual Abortion: 1 to 2 tablets daily with the confirmation of pregnancy. Administration should be continued until at least one month after the critical period.Threatened Premature Labour: 40 mg daily until symptoms improve.Failure of Nidation: 2 - 4 tablets daily from 16th to 26th day of the cycle until conception is achieved.Side EffectsGastrointestinal complaints like nausea, vomiting etc. have been reported.Drug InteractionNo drug- drug interactions have been reported.Over DoseIf you have taken several capsules at once, there is no need for great concern. However, you should consult your doctor. The oily substance in the capsule may cause diarrhea.Storage- Store in a cool, dry place- Keep away from light & out of reach of childrenCommercial PackAlestor: Each box contains 3 blisters each containing 10 tablets...

Tk.8.00/=

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Algicid suspension

Algicid suspension

DescriptionAlgicid works by forming a raft (thick layer) on top of the stomach contents soon after it has made contact with the stomach acid. The raft acts as a strong physical barrier and helps keep all the components of the stomach contents in the stomach where they work, not letting them seep back up into the esophagus where they hurt.IndicationsTreatment of symptoms of gastro-oesophageal reflux, such as acid regurgitation, heartburn and indigestion (related to reflux), for example, following meals or during pregnancy or in patients with symptoms related to reflux esophagitis.Dosage & AdministrationDaily 4 times, after meals & before bedtime.TabletAdult and child over 12 years: 1-2 tablets.Child 6-12 years: 1 tablet.SuspensionAdult and child over 12 years: 5-10 ml.Child 2-12 years: 2.5-5 ml.Algicid is not recommended for children under 2 years of age.Side EffectsIn addition to the desired effect of the drug, some side effects may appear such as: nausea, constipation, diarrhea or headache. In these cases consult a physician. In case too big dosage has been taken, there might appear a sensation of swelling. In this case it is advisable to consult a physician.PrecautionsAlgicid should be prescribed with caution in patients with renal impairment and congestive cardiac failure.Use in Pregnancy & LactationAlgicid can be given in pregnant and lactating women.Drug InteractionIf you are taking other medicines concomitantly, or have just completed another drug treatment, inform your physician in order to prevent hazards or inefficacy arising from drug interactions.Over DoseOver dosage with this formulation is a rare case. In case of overdose please consult with a registered physician.StorageStore in a cool place (in room temperature, below 30 °C)...

Tk.150.00/=

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Algicid Tablet

Algicid Tablet

IndicationsTreatment of symptoms of gastro-oesophageal reflux, such as acid regurgitation, heartburn and indigestion (related to reflux), for example, following meals or during pregnancy or in patients with symptoms related to reflux esophagitis.DescriptionsAlgicid works by forming a raft (thick layer) on top of the stomach contents soon after it has made contact with the stomach acid. The raft acts as a strong physical barrier and helps keep all the components of the stomach contents in the stomach where they work, not letting them seep back up into the esophagus where they hurt.Dosage & AdministrationDaily 4 times, after meals & before bedtime. Tablet Adult and child over 12 years: 1-2 tablets. Child 6-12 years: 1 tablet. Suspension Adult and child over 12 years: 5-10 ml. Child 2-12 years: 2.5-5 ml. Algicid is not recommended for children under 2 years of age.Side EffectsIn addition to the desired effect of the drug, some side effects may appear such as: nausea, constipation, diarrhea or headache. In these cases consult a physician. In case too big dosage has been taken, there might appear a sensation of swelling. In this case it is advisable to consult a physician.PrecautionsAlgicid should be prescribed with caution in patients with renal impairment and congestive cardiac failure.ContraindicationsSodium alginate and potassium bicarbonate is contraindicated in patients with known hypersensitivity to these.Use in Pregnancy & LactationAlgicid can be given in pregnant and lactating women.Drug InteractionIf you are taking other medicines concomitantly, or have just completed another drug treatment, inform your physician in order to prevent hazards or inefficacy arising from drug interactions.OverdoseOver dosage with this formulation is a rare case. In case of overdose please consult with a registered physician.StorageStore in a cool place (in room temperature, below 30 °C).Commercial PackagingAlgicid tablet: Each box contains 10 blisters of 10 tablets. Algicid suspension: Bottle containing 200 ml of suspension...

Tk.3.50/=

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Alneed Capsule

Alneed Capsule

DescriptionAlneed is a special preparation of Iron, Folic acid, B-vitamins and Vitamin-C.IndicationsAlneed is indicated for the treatment and prophylaxis of Iron, Folic acid, B-vitamins and Vitamin-C deficiency, especially during pregnancy and lactation.Dosage & AdministrationOne capsule daily. In more severe cases, 2 capsules a day may be required or as directed by the physician.Side EffectsGenerally well tolerated. However, a few allergic reactions may be seen.PrecautionsCare should be taken in patients who may develop iron overload, such as those with hemochromatosis, haemolytic anaemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.Use in Pregnancy & LactationRecommended.Over DoseAccidental overdose of iron containing products is a leading cause of fatal poisoning in children fewer than 6. Avoid higher doses if you have liver disease or hemochromatosis; excess can cause bloody diarrhea, vomiting, acidosis, darkened stools, abdominal pain. Symptoms may clear in a few hours. Riboflavin is reported to be completely safe and no toxic symptoms have been reported so far. Higher doses of Nicotinamide may cause vomiting, diarrhea. Sensory neuropathy was observed in individuals consuming more than 200 mg Pyridoxine for very long periods. No cases of Folic acid overdosages have been reported. Acute ingestion of Ascorbic acid, even of massive doses, is unlikely to cause significant effects.StorageStore in a dry place below 25 °C. Protect from light...

Tk.3.00/=

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Alneed Gold Capsule.

Alneed Gold Capsule.

IndicationsAlneed Gold is indicated for the treatment and prophylaxis of Zinc, Iron, Folic Acid, B-vitamins deficiency especially during pregnancy and lactation.DescriptionsAlneed Gold is a special preparation of Iron Polymaltose Complex, Folic Acid, Zinc, and B-vitamins. Iron Polymaltose Complex is a water soluble, macromolecular complex of poly nuclear iron (III) hydroxide and partially hydrolysed dextrin ( Polymaltose). It does not interact with the food components and other medications and so there is no decrease in bioavailability of Iron Polymaltose Complex. This makes sure that with the consumption of this complex, iron gets utilized at a faster rate in the haemoglobin synthesis. Folic acid prevents neural tube defects. Zinc is essential for many metabolic processes, blood formation, wound healing and for immune system. Thiamine is essential for the functioning of the nervous and digestive systems. Riboflavin is important for digestion, immune system support and energy production. Pyridoxin is important for brain development, production of red blood cells, metabolism of proteins and to reduce morning sickness. Nicotinamide is important for energy, blood pressure and circulation. Dosage & AdministrationOne capsule daily. In more severe cases, 2 capsules a day may be required or as directed by the physician.Side EffectsGenerally well tolerated. However, a few allergic reactions may be seen.PrecautionsCare should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anaemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.ContraindicationsThis product is contraindicated in patients with a known hypersensitivity to any of the ingredients.OverdoseAccidental overdose of iron containing products is a leading cause of fatal poisoning in children below 6 years. Avoid higher doses if you have liver disease or haemochromatosis; excess can cause bloody diarrhea, vomiting, acidosis, darkened stools, abdominal pain. Symptoms may clear in a few hours. Riboflavin is reported to be completely safe and no toxic symptoms have been reported so far. Higher doses of Nicotinamide may cause vomiting, diarrhea. Sensory neuropathy was observed in individuals consuming more than 200 mg Pyridoxine for very long periods. No case of Folic acid overdodage has been reported. Zinc toxicity has been seen in both acute and chronic forms. Ingestion of 150 to 450 mg of zinc per day have been associated with low copper status, altered iron function, reduced immune function, and reduced levels of high-density lipoproteins. So, Zinc at its RDA dosages dose not cause any significant effect.StorageStore in a dry place below 25 °C. Protect from light.Commercial PackagingAlneed Gold capsule: Each box contains 3 blister strips of 10 capsule...

Tk.6.00/=

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Alneed PLUS Cap

Alneed PLUS Cap

DescriptionAlneed Plus is a special preparation of Zinc, Iron, Folic Acid, B-vitamins and Vitamin-C.IndicationsAlneed Plus is indicated for the treatment and prophylaxis of Zinc, Iron, Folic Acid, B-vitamins and Vitamin-C deficiency especially during pregnancy and lactation.Dosage & AdministrationOne capsule daily. In more severe cases, 2 capsules a day may be required or as directed by the physician.Side EffectsGenerally well tolerated. However, a few allergic reactions may be seen.PrecautionsCare should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anaemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.Use in Pregnancy & LactationRecommended.Over DoseAccidental overdose of iron containing products is a leading cause of fatal poisoning in children below 6 years. Avoid higher doses if you have liver disease or haemochromatosis; excess can cause bloody diarrhea, vomiting, acidosis, darkened stools, abdominal pain. Symptoms may clear in a few hours.Riboflavin is reported to be completely safe and no toxic symptoms have been reported so far. Higher doses of Nicotinamide may cause vomiting, diarrhea. Sensory neuropathy was observed in individuals consuming more than 200 mg Pyridoxine for very long periods. No case of Folic acid overdodage has been reported.Acute ingestion of Ascorbic acid, even of massive doses, is unlikely to cause significant effects.Zinc toxicity has been seen in both acute and chronic forms. Ingestion of 150 to 450 mg of zinc per day have been associated with low copper status, altered iron function, reduced immune function, and reduced levels of high-density lipoproteins. So, Zinc at its RDA dosages dose not cause any significant effect.StorageStore in a dry place below 25 °C. Protect from light...

Tk.3.50/=

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Aloxif Tab

Aloxif Tab

Aloxif TabDescriptionRaloxifene is a selective estrogen receptor modulator (SERM). The biological actions of Raloxifene are largely mediated through binding to estrogen receptor. This binding results in activation of certain estrogenic pathways and blockade of others. Raloxifene reduces resorption of bone and decreases overall bone turnover. These effects on bone are manifested as reductions in the serum and urine levels of bone turnover markers. Clinical trials and data suggest that Raloxifene lacks estrogen like effects on the uterus and breast tissues. Raloxifene is rapidly absorbed after oral administration, metabolized in liver, and primarily excreted in faeces and rest in urine.IndicationsTreatment and prevention of post-menopausal osteoporosis.Dosage & AdministrationOne tablet (60 mg) once daily orally. It can be taken without regard to meal. High fat meal increases the absorption of Raloxifene.Side EffectsRaloxifene is generally well tolerated. However, a few side effects like hot flushes, leg cramps, and influenza like symptoms, gastro-intestinal disturbances etc may be seen usually during first 6 months of treatment and were not different from placebo.PrecautionsConcurrent Estrogen Therapy: Concomitant use of Raloxifene with systemic estrogens is not recommended.Lipid Metabolism: Concurrent use of Raloxifene and lipid-lowering agents has not been studied.Use in Pregnancy & LactationPregnancy: Raloxifene should not be used in women who are or may become pregnant.Lactation period: It is not known whether Raloxifene is excreted in breast milk. Lactating mother should not use Raloxifne.Drug InteractionCo-administered with cholestyramin, ampicillin and amoxicillin may reduce the absorption of Raloxifene.Over DoseIncidents of overdose in humans have not been reported.Commercial PackAloxif : Each box contains 3 blister strips of 10 tablets...

Tk.14.00/=

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Ambolyt Paediatric Drops

Ambolyt Paediatric Drops

Indications• Acute and chronic diseases of respiratory tracts associated with viscid mucus including acute and chronic bronchitis • Productive cough • Inflammatory diseases of Rhinopharyngeal tract (e.g. Laryngitis, Pharyngitis, Sinusitis and Rhinitis) associated with viscid mucus • Asthmatic bronchitis, Bronchial asthma with difficult departure of mucus • Bronchiectasis • Chronic pneumonia.DescriptionsAmbroxol is a metabolite of Bromhexine. It possesses mucokinetic (improvement in mucus transport) and secretolytic (liquefies secretions) properties. Ambroxol stimulates the serous cells of the glands of the mucous membrane of bronchi, increasing the content of mucus secretion. The mucolytic effect is associated with depolymerization and splitting of mucoproteins and mucopolysaccharide fibres, which leads to reduction in the viscosity of mucus. Expectoration of mucus is facilitated and breathing is eased considerably. Ambroxol stimulates production of phospholipids of surfactant by alveolar cells. Ambroxol has anti-inflammatory properties. In patients with COPD, it improves airway patency. Beside these, Ambroxol also exhibits anti-oxidant activity. Long-term use is possible because of the good tolerability of the preparation. Dosage & AdministrationAverage daily dose (preferably after meal). Ambolyt Paediatric Drops: 0-6 months 0.5 ml 2 times a day 6-12 months 1 ml 2 times a day 1-2 years 1.25 ml 2 times a day Ambolyt Syrup: 2-5 years 2.5 ml (1/2 teaspoonful) 2-3 times a day 5-10 years 5 ml (1 teaspoonful) 2-3 times a day 10 years and adults 10 ml (2 teaspoonful) 3 times a day.Side EffectsGastrointestinal side-effects like epigastric pain, gastric fullness may occur occasionally. Rarely allergic responses such as eruption, urticaria or angioneurotic edema may occur.PrecautionsAmbroxol should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.ContraindicationsContraindicated in known hypersensitivity to Ambroxol or Bromhexine.Use in Pregnancy & LactationPregnancy: Teratogenic and fetal toxicity studies have shown no harmful effect of Ambroxol. However, it is advised not to use during pregnancy, especially in the 1st trimester. Lactation: Safety during lactation has not been established.Drug InteractionAmbroxol has no interaction with cardioactive glycosides, corticosteroids, bronchodilators, diuretics and antibiotics (normally used in the treatment of bronchopulmonary affections). But Ambroxol should not be taken simultaneously with antitussives (e.g. Codeine) because mucus, which has been liquefied by Ambroxol, might not be expectorated.Commercial PackagingAmbolyt Syrup: Amber color bottle containing 100 ml syrup and a measuring cup. Ambolyt Paediatric Drops: Amber color bottle containing 15 ml paediatric drops and a calibrated dropper..

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Ambolyt Syrup

Ambolyt Syrup

Indications• Acute and chronic diseases of respiratory tracts associated with viscid mucus including acute and chronic bronchitis • Productive cough • Inflammatory diseases of Rhinopharyngeal tract (e.g. Laryngitis, Pharyngitis, Sinusitis and Rhinitis) associated with viscid mucus • Asthmatic bronchitis, Bronchial asthma with difficult departure of mucus • Bronchiectasis • Chronic pneumonia.DescriptionsAmbroxol is a metabolite of Bromhexine. It possesses mucokinetic (improvement in mucus transport) and secretolytic (liquefies secretions) properties. Ambroxol stimulates the serous cells of the glands of the mucous membrane of bronchi, increasing the content of mucus secretion. The mucolytic effect is associated with depolymerization and splitting of mucoproteins and mucopolysaccharide fibres, which leads to reduction in the viscosity of mucus. Expectoration of mucus is facilitated and breathing is eased considerably. Ambroxol stimulates production of phospholipids of surfactant by alveolar cells. Ambroxol has anti-inflammatory properties. In patients with COPD, it improves airway patency. Beside these, Ambroxol also exhibits anti-oxidant activity. Long-term use is possible because of the good tolerability of the preparation. Dosage & AdministrationAverage daily dose (preferably after meal). Ambolyt Paediatric Drops: 0-6 months 0.5 ml 2 times a day 6-12 months 1 ml 2 times a day 1-2 years 1.25 ml 2 times a day Ambolyt Syrup: 2-5 years 2.5 ml (1/2 teaspoonful) 2-3 times a day 5-10 years 5 ml (1 teaspoonful) 2-3 times a day 10 years and adults 10 ml (2 teaspoonful) 3 times a day.Side EffectsGastrointestinal side-effects like epigastric pain, gastric fullness may occur occasionally. Rarely allergic responses such as eruption, urticaria or angioneurotic edema may occur.PrecautionsAmbroxol should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.ContraindicationsContraindicated in known hypersensitivity to Ambroxol or Bromhexine.Use in Pregnancy & LactationPregnancy: Teratogenic and fetal toxicity studies have shown no harmful effect of Ambroxol. However, it is advised not to use during pregnancy, especially in the 1st trimester. Lactation: Safety during lactation has not been established.Drug InteractionAmbroxol has no interaction with cardioactive glycosides, corticosteroids, bronchodilators, diuretics and antibiotics (normally used in the treatment of bronchopulmonary affections). But Ambroxol should not be taken simultaneously with antitussives (e.g. Codeine) because mucus, which has been liquefied by Ambroxol, might not be expectorated.Commercial PackagingAmbolyt Syrup: Amber color bottle containing 100 ml syrup and a measuring cup. Ambolyt Paediatric Drops: Amber color bottle containing 15 ml paediatric drops and a calibrated dropper..

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Ameloss 5 Tab

Ameloss 5 Tab

Ameloss 5 TabDescriptionDonepezil Hydrochloride is a centrally acting anticholinesterase agent. It binds reversibly with acetylcholinesterase and inactivates it, thus inhibiting hydrolysis of acetylcholine. As a result the concentration of acetylcholine increases at cholinergic synapses in the brain.IndicationsAmeloss is indicated for the symptomatic treatment of mild to moderate dementia of Alzheimer's type.Dosage & Administration1 tab of 5 mg once daily orally at bed time. The 5 mg (1 tab)/day dose should be maintained for at least one month in order to allow the earliest clinical responses to treatment to be assessed and to allow steady-state concentrations of donepezil hydrochloride to be achieved. Following a one-month clinical assessment of treatment at 5 mg/day, the dose can be increased to 10 mg/day (once-a-day dosing). Since food does not affect the rate or extent of absorption of donepezil, it can be administered with or without food.In case of renal & hepatic impairment: A similar dose schedule can be followed for patients with renal or mild to moderate hepatic impairment as clearance of donepezil hydrochloride is not affected by these conditions.In case of children: There are no adequate and well controlled trials in document to safety and efficacy of donepezil hydrochloride in any illness occurring in children. Donepezil is not recommended for use in children.Side EffectsGenerally well tolerated but some patients may experience nausea, vomiting & diarrhoea. These adverse events are of mild intensity and transient, resolving during continued treatment without the need for dose modification. Less frequent side effects are insomnia, fatigue, anorexia, muscle cramps, generalized seizure etc.PrecautionsCaution should be taken in sick sinus syndrome or other supraventricular conduction abnormalities, patients at risk of developing peptic ulcers, asthma, obstructive airway disease and during anaesthetic procedure.Use in Pregnancy & LactationPregnancy: There are no adequate and well controlled studies in pregnant woman. Donepezil should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.Nursing Mother: It is not known whether Donepezil Hydrochloride is secreted in human breast milk or not. Donepezil is not indicated in nursing mother.Drug InteractionDrugs with anticholinergic properties and which cross into the brain, such as atropine, benztropine produce the opposite effects of Donepezil and should be avoided during therapy with donepezil. Medication with carbamazepine, dexamethasone, phenobarbital, phenytoin may reduce the effect of donepezil whereas ketoconazole, quinidine, cimetidine may increase the effects.Over DoseSymptoms of overdose includes nausea, vomiting, salivation. Over dosage with very high dose of donepezil may result in cholinergic crisis characterized by severe nausea, vomiting, salivation, bradycardia, hypotension, increasing muscle weakness, respiratory depression, collapse and convulsion. As in any case of over dose, general supportive measures should be utilized. In case of cholinergic crisis hospitalization of the patient is required.Commercial PackAmeloss 5: Each box contains 3 blister strips of 10 tablets...

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Amidol 300 50 vial

Amidol 300 50 vial

IndicationsNEURORADIOLOGY-Lumber myelography, thoraco-cervical myelography, ANGIOGRAPHY- Cerebral angiography, selective coronary angiography, left ventriculography, aortography, angiocadiography, selective visceral arteriography, peripheral arteriography, digital subtraction angiography, venography, urography, OTHER DIAGNOSTIC PROCEDURES-Contrast enhancement in CT scanning, arthrography, fistulography.DescriptionsIopamidol, an organic Iodine compound and used as a non-ionic water soluble radiographic contrast medium. Iopamidol blocks X-rays as they pass through the body, thereby allowing body structures not containing Iodine to be visualized. The degree of opacity produced by Iopamidol is directly proportional to the total amount of the iodinated contrast agent in the path of the X-rays. The visualization of body structures is dependent upon the distribution and elimination of Iopamidol.Dosage & AdministrationAdult dosage NEURORADIOLOGY Lumber myelography: Amidol 300, 5-10 ml; Amidol 370, 6-13 ml Thoraco-cervical myelography: Amidol 300, 5-10 ml; Amidol 370, 6-13 ml ANGIOGRAPHY Cerebral angiography: Amidol 300, 5-10 ml; Amidol 370, 6-13 ml Selective coronary arteriography: Amidol 300/370, 4-8 ml/artery Peripheral arteriography: Amidol 300/370, 20-50 ml Venography: Amidol 300, 20-50 ml; Amidol 370, 24-60 ml Angiocardiography: Amidol 300/370, 30-80 ml Left ventriculography: Amidol 300/370, 30-80 ml Percutaneous transfemoral / renal arteriography: Amidol 300/370, 30 ml Selective renal arteriography: Amidol 300/370, 5-10 ml Selective visceral arteriography: Hepatic angiography: Amidol 300, 30 ml; Amidol 370, 70 ml Coeliac angiography: Amidol 300/370, 40-70 ml Superior mesenteric angiography: Amidol 300/370, 25-50 ml Inferior mesenteric angiography: Amidol 300/370, 5-30 ml Digital subtraction angiography: 30-50ml (10-20 ml/sec ) of Amidol 300/370,i.v 25 ml (left ventricle), 2-5 ml (coronary arteries) ,15 ml/sec. of Amidol 300/370 i.a for cardiac imaging UROGRAPHY Amidol 300/370, 40-80 ml i.v up to 1.5 ml/kg in severe renal disease. OTHER DIAGNOSTIC PROCEDURES Contrast enhancement in CT scanning: Amidol 300/370, 0.5-2.0 ml /kg Arthrography: Amidol 300, 1-10 ml Children: 1-2.5 ml/kg. Method of administration NEURORADIOLOGY Lumber myelography: A slow sub-arachnoid injection is made through a fine lumber puncture needle into one of the lower interspinous spaces (L3-L4 or L4-L5). Optimum contrast appears immediately after injections and films should be obtained promptly. Thoraco-cervical myelography: Following a slow sub-arachnoid injection the patient should be turned on his/her side and tilted 10o-20o head down under fluoroscopic control. In this manner it is possible to control movement of the contrast medium column into the dorsal region. If the cervical region is to be examined, the contrast medium should be run into the cervical region first, before the examination of the dorsal areas where it is progressively diluted. Amidol 300/370 may also be injected sub-occipitally or by lateral puncture technique .Care should be taken to ensure that the contrast medium does not move intracranially. It is generally recommended that in intrathecal use the patient should remain with a raised bed head and be kept well hydrated; following hydration it is preferable that the patient be allowed to be ambulatory . ANGIOGRAPHY Cerebral angiography: Any current technique is suitable for radiological visualization of the cerebral vasculature with Amidol 370/300 injection. Carotid and vertebral angiography, performed by catheterization or percutaneous injection techniques, require rapid injection which, if necessary, may be repeated. Peripheral arteriography and venography: Percutaneous injection into the appropriate blood vessel is used for visualization of peripheral arteries and veins. Angiocardiography, left ventriculography, selective coronary arteriography: Amidol 370/300 injection may be administered by rapid injection through a catheter into a suitable peripheral artery or vein. It can also be introduced under pressure through a cardiac catheter in to any of the heart chambers, or injected into large vessel for immediate visualization. The contrast medium may also be administered during selective catheterization of the coronary arteries. Aortography: The contrast medium may be introduced directly or by intra-arterial injection for visualization of the aorta and its main branches. Selective visceral angiography: Visualization can be achieved by selective catheterization and injection into the hepatic, coeliac or mesenteric arteries. Digital subtraction angiography: For cardiac imaging the contrast medium may be administered intra-arterially by selective catheterization to provide substrated images. Amidol 370/300 injected intravenously either centrally or peripherally is also recommended for use this modality. UROGRAPHY The contrast medium injected intravenously and rapid..

Tk.1,203.00/=

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Amidol 370 50 vial

Amidol 370 50 vial

IndicationsNEURORADIOLOGY-Lumber myelography, thoraco-cervical myelography, ANGIOGRAPHY- Cerebral angiography, selective coronary angiography, left ventriculography, aortography, angiocadiography, selective visceral arteriography, peripheral arteriography, digital subtraction angiography, venography, urography, OTHER DIAGNOSTIC PROCEDURES-Contrast enhancement in CT scanning, arthrography, fistulography.DescriptionsIopamidol, an organic Iodine compound and used as a non-ionic water soluble radiographic contrast medium. Iopamidol blocks X-rays as they pass through the body, thereby allowing body structures not containing Iodine to be visualized. The degree of opacity produced by Iopamidol is directly proportional to the total amount of the iodinated contrast agent in the path of the X-rays. The visualization of body structures is dependent upon the distribution and elimination of Iopamidol.Dosage & AdministrationAdult dosage NEURORADIOLOGY Lumber myelography: Amidol 300, 5-10 ml; Amidol 370, 6-13 ml Thoraco-cervical myelography: Amidol 300, 5-10 ml; Amidol 370, 6-13 ml ANGIOGRAPHY Cerebral angiography: Amidol 300, 5-10 ml; Amidol 370, 6-13 ml Selective coronary arteriography: Amidol 300/370, 4-8 ml/artery Peripheral arteriography: Amidol 300/370, 20-50 ml Venography: Amidol 300, 20-50 ml; Amidol 370, 24-60 ml Angiocardiography: Amidol 300/370, 30-80 ml Left ventriculography: Amidol 300/370, 30-80 ml Percutaneous transfemoral / renal arteriography: Amidol 300/370, 30 ml Selective renal arteriography: Amidol 300/370, 5-10 ml Selective visceral arteriography: Hepatic angiography: Amidol 300, 30 ml; Amidol 370, 70 ml Coeliac angiography: Amidol 300/370, 40-70 ml Superior mesenteric angiography: Amidol 300/370, 25-50 ml Inferior mesenteric angiography: Amidol 300/370, 5-30 ml Digital subtraction angiography: 30-50ml (10-20 ml/sec ) of Amidol 300/370,i.v 25 ml (left ventricle), 2-5 ml (coronary arteries) ,15 ml/sec. of Amidol 300/370 i.a for cardiac imaging UROGRAPHY Amidol 300/370, 40-80 ml i.v up to 1.5 ml/kg in severe renal disease. OTHER DIAGNOSTIC PROCEDURES Contrast enhancement in CT scanning: Amidol 300/370, 0.5-2.0 ml /kg Arthrography: Amidol 300, 1-10 ml Children: 1-2.5 ml/kg. Method of administration NEURORADIOLOGY Lumber myelography: A slow sub-arachnoid injection is made through a fine lumber puncture needle into one of the lower interspinous spaces (L3-L4 or L4-L5). Optimum contrast appears immediately after injections and films should be obtained promptly. Thoraco-cervical myelography: Following a slow sub-arachnoid injection the patient should be turned on his/her side and tilted 10o-20o head down under fluoroscopic control. In this manner it is possible to control movement of the contrast medium column into the dorsal region. If the cervical region is to be examined, the contrast medium should be run into the cervical region first, before the examination of the dorsal areas where it is progressively diluted. Amidol 300/370 may also be injected sub-occipitally or by lateral puncture technique .Care should be taken to ensure that the contrast medium does not move intracranially. It is generally recommended that in intrathecal use the patient should remain with a raised bed head and be kept well hydrated; following hydration it is preferable that the patient be allowed to be ambulatory . ANGIOGRAPHY Cerebral angiography: Any current technique is suitable for radiological visualization of the cerebral vasculature with Amidol 370/300 injection. Carotid and vertebral angiography, performed by catheterization or percutaneous injection techniques, require rapid injection which, if necessary, may be repeated. Peripheral arteriography and venography: Percutaneous injection into the appropriate blood vessel is used for visualization of peripheral arteries and veins. Angiocardiography, left ventriculography, selective coronary arteriography: Amidol 370/300 injection may be administered by rapid injection through a catheter into a suitable peripheral artery or vein. It can also be introduced under pressure through a cardiac catheter in to any of the heart chambers, or injected into large vessel for immediate visualization. The contrast medium may also be administered during selective catheterization of the coronary arteries. Aortography: The contrast medium may be introduced directly or by intra-arterial injection for visualization of the aorta and its main branches. Selective visceral angiography: Visualization can be achieved by selective catheterization and injection into the hepatic, coeliac or mesenteric arteries. Digital subtraction angiography: For cardiac imaging the contrast medium may be administered intra-arterially by selective catheterization to provide substrated images. Amidol 370/300 injected intravenously either centrally or peripherally is also recommended for use this modality. UROGRAPHY The contrast medium injected intravenously and rapid..

Tk.1,318.00/=

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Amikin 100 Inj

Amikin 100 Inj

Amikin 100 InjPresentationAmikin 100 IM/IV Injection: Each 2ml ampoule contains 100 mg Amikacin as Amikacin Sulfate USP.DescriptionAmikacin Sulfate is a semi-synthetic aminoglycoside antibiotic. Amikacin is active in vitro against Pseudomonas species, Escherichia coli, Proteus species, Providencia species, Klebsiella-Enterobacter species, Acinetobacter species, and Citrobacter freundii. When strains of the above organisms are found to be resistant to other aminoglycosides, including Gentamicin, TobrAmykin and KanAmykin, many are susceptible to Amikacin. Amikacin sulfate is active in vitro against penicillinase and nonpenicillinase-producing Staphylococcus species including methicillin-resistant strains.IndicationsAmikacin is indicated in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. It is effective in bacterial septicemia (including neonatal sepsis); in serious infections of the respiratory tract, bones and joints, central nervous system (including meningitis) and skin and soft tissue; intra abdominal infections (including peritonitis); and in bums and post operative infections (including post-vascular surgery). Amikacin is also effective in serious complicated and recurrent urinary tract infections due to susceptible Gram-negative organisms. It may be considered as initial therapy in suspected Gram-negative infections and therapy may be instituted before obtaining the results of susceptibility. Amikacin is also effective in infections caused by Gentamycln and/or TobrAmykin resistant strains of Gram-negative organisms. Amikacin has also been shown to be effective in Staphylococcal infection and may be considered as initial therapy under certain condition in the treatment of known suspected Staphylococcal disease such as, severe infections where the causative organism may either a Gram-negative bacterium or Staphylococcus infection due to susceptible strains of Staphylococcal I Gram-negative infections. In certain severe infections such as neonatal sepsis, concomitant therapy with a penicillin type drug may be indicated because of the possibility of infections due to Gram positive organism such as streptococci or pneumococci.Dosage & AdministrationAdults and children: 15mg/kg/day in two equally- divided doses (equivalent to 500 mg bid in adults). Use of the 100 mg/2 ml strength is recommended for children for the accurate measurement of the appropriate dose.Neonates and premature children: An initial loading dose of 10 mg/kg followed by 15 mg/kg/day in two equally divided doses.Elderly: Doses should be adjusted under impaired renal function in elderly.Life-threatening infections and/or those caused by pseudomonas: The adult dose may be increased to 500 mg every eight hours but should neither exceed 1.5 gm/day nor be administered for a period longer than 10 days. A maximum total adult dose of 15 gm should not be exceeded.Urinary tract infections (Other than pseudomonal infections): 7.5 mg/kg/day in two equally divided doses (equivalent to 250 mg bid in adults).Impaired renal function: In patient with impaired renal function the daily dose should be reduced and/or the intervals between doses increased to avoid accumulation of the drug. Simple doses schedule for renal impairment is given below:Renal function Dosage scheduleMild impairment 500 mg every 18 hoursModerate impairment 500 mg every 24 hoursSevere impairment 250 mg every 24 hours.Administration:Intramuscular or intravenous administration: For most infections the intramuscular route is preferred, but in life threatening infections, or in patients in whom intramuscular injection route is not feasible the intravenous route may be used.Intraperitoneal use: Amikacin may be used as an irrigant after recovery from anesthesia in concentration of 0.25%.Other routes of administration: Amikacin in concentration of 0.25% may be used satisfactorily as an irrigating solution in abscess cavities, the pleural space, the peritoneum and the cerebral ventricles.Side EffectsWhen the recommended precautions and dosages are followed the incidence of toxic reactous, such as tinnitus vertigo, and partial reversible or irreversible deafness, skin rash, drug fever, headache, paraesthesia, nausea and vomiting is low. Urinary signs of renal irritation, azotaemia and oliguria have been reported.PrecautionsSince Amikacin is present in high concentrations in the renal excretory system, patients should be well hydrated to minimize chemical irritation of the renal tubules. If azotemia increases, treatment should be stopped. Monitoring of renal function during treatment with aminoglycosides is particularly important.Use in Pregnancy & LactationThe safety of Amikacin in pregnancy has not yet been established.Drug InteractionNo information regarding drug interaction of Amikacin is available.Over DoseIn the event of overdose or toxic reaction, peritoneal dialysis or hemodialysis will aid in the removal of Amikacin from the blo..

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Amikin 500 Inj

Amikin 500 Inj

Amikin 500 InjPresentationAmikin 500 IM/IV Injection: Each 2ml ampoule contains 500 mg Amikacin as Amikacin Sulfate USP.DescriptionAmikacin Sulfate is a semi-synthetic aminoglycoside antibiotic. Amikacin is active in vitro against Pseudomonas species, Escherichia coli, Proteus species, Providencia species, Klebsiella-Enterobacter species, Acinetobacter species, and Citrobacter freundii. When strains of the above organisms are found to be resistant to other aminoglycosides, including Gentamicin, TobrAmykin and KanAmykin, many are susceptible to Amikacin. Amikacin sulfate is active in vitro against penicillinase and nonpenicillinase-producing Staphylococcus species including methicillin-resistant strains.IndicationsAmikacin is indicated in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. It is effective in bacterial septicemia (including neonatal sepsis); in serious infections of the respiratory tract, bones and joints, central nervous system (including meningitis) and skin and soft tissue; intra abdominal infections (including peritonitis); and in bums and post operative infections (including post-vascular surgery). Amikacin is also effective in serious complicated and recurrent urinary tract infections due to susceptible Gram-negative organisms. It may be considered as initial therapy in suspected Gram-negative infections and therapy may be instituted before obtaining the results of susceptibility. Amikacin is also effective in infections caused by Gentamycln and/or TobrAmykin resistant strains of Gram-negative organisms. Amikacin has also been shown to be effective in Staphylococcal infection and may be considered as initial therapy under certain condition in the treatment of known suspected Staphylococcal disease such as, severe infections where the causative organism may either a Gram-negative bacterium or Staphylococcus infection due to susceptible strains of Staphylococcal I Gram-negative infections. In certain severe infections such as neonatal sepsis, concomitant therapy with a penicillin type drug may be indicated because of the possibility of infections due to Gram positive organism such as streptococci or pneumococci.Dosage & AdministrationAdults and children: 15mg/kg/day in two equally- divided doses (equivalent to 500 mg bid in adults). Use of the 100 mg/2 ml strength is recommended for children for the accurate measurement of the appropriate dose.Neonates and premature children: An initial loading dose of 10 mg/kg followed by 15 mg/kg/day in two equally divided doses.Elderly: Doses should be adjusted under impaired renal function in elderly.Life-threatening infections and/or those caused by pseudomonas: The adult dose may be increased to 500 mg every eight hours but should neither exceed 1.5 gm/day nor be administered for a period longer than 10 days. A maximum total adult dose of 15 gm should not be exceeded.Urinary tract infections (Other than pseudomonal infections): 7.5 mg/kg/day in two equally divided doses (equivalent to 250 mg bid in adults).Impaired renal function: In patient with impaired renal function the daily dose should be reduced and/or the intervals between doses increased to avoid accumulation of the drug. Simple doses schedule for renal impairment is given below:Renal function Dosage scheduleMild impairment 500 mg every 18 hoursModerate impairment 500 mg every 24 hoursSevere impairment 250 mg every 24 hours.Administration:Intramuscular or intravenous administration: For most infections the intramuscular route is preferred, but in life threatening infections, or in patients in whom intramuscular injection route is not feasible the intravenous route may be used.Intraperitoneal use: Amikacin may be used as an irrigant after recovery from anesthesia in concentration of 0.25%.Other routes of administration: Amikacin in concentration of 0.25% may be used satisfactorily as an irrigating solution in abscess cavities, the pleural space, the peritoneum and the cerebral ventricles.Side EffectsWhen the recommended precautions and dosages are followed the incidence of toxic reactous, such as tinnitus vertigo, and partial reversible or irreversible deafness, skin rash, drug fever, headache, paraesthesia, nausea and vomiting is low. Urinary signs of renal irritation, azotaemia and oliguria have been reported.PrecautionsSince Amikacin is present in high concentrations in the renal excretory system, patients should be well hydrated to minimize chemical irritation of the renal tubules. If azotemia increases, treatment should be stopped. Monitoring of renal function during treatment with aminoglycosides is particularly important.Use in Pregnancy & LactationThe safety of Amikacin in pregnancy has not yet been established.Drug InteractionNo information regarding drug interaction of Amikacin is available.Over DoseIn the event of overdose or toxic reaction, peritoneal dialysis or hemodialysis will aid in the removal of Amikacin from the blo..

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Amlosartan 10/160 Tab

Amlosartan 10/160 Tab

Indications Amlodipine and Valsartan combination is indicated for the treatment of hypertension. This fixed combination drug is not indicated for the initial therapy of hypertension Therapeutic Class Combined antihypertensive preparations Pharmacology Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II by selectively blocking the binding of Angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for Angiotensin II synthesis. Amlodipine and Valsartan have been shown to be effective in lowering blood pressure. Both Amlodipine and Valsartan lower blood pressure by reducing peripheral resistance, but calcium influx blockade and reduction of Angiotensin II vasoconstriction are complementary mechanisms. Dosage & Administration Amlodipine is an effective treatment of hypertension in once daily doses of 2.5 mg-10 mg while Valsartan is effective in doses of 80 mg-320 mg. In clinical trials with Amlodipine and Valsartan combination using Amlodipine doses of 5 mg-10 mg and Valsartan doses of 160 mg-320 mg, the antihypertensive effects increased with increasing doses. Interaction No drug interaction studies have been conducted with Amlodipine and Valsartan combination and other drugs, although studies have been conducted with the individual Amlodipine and Valsartan components Contraindications Amlodipine and Valsartan combination is contraindicated in patients who are hypersensitive to any compounds of this product. Side Effects The most common side effects include peripheral edema, vertigo, nasopharyngitis, upper respiratory tract infection and dizziness. Pregnancy & Lactation Pregnancy: Amlodipine and Valsartan combination should not be used in 2nd and 3rd trimester because it can cause fetal death .Nursing Mothers: It is not known whether Valsartan and Amlodipine are excreted in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother. Precautions Amlosartan should be used with caution because there is a risk for fetal or neonatal morbidity, hypotension, myocardial infarction or increased angina.Dose should be titrated slowly in patients with impaired hepatic or severely impaired renal function. In general, calcium channel blockers should be used with caution in patients with heart failure. Overdose Effects Limited data of human overdosage have been reported. Use in Special Population Pediatric use: The safety and effectiveness has not been established in pediatric patients.Geriatric use: No differences in overall incidence of adverse events were observed in elderly.Renal impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment. Titrate slowly in patients with severe renal impairment. Hepatic impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency. Titrate slowly in patients with hepatic impairment. Storage Conditions Store in a cool dry place protected from light. Keep out of reach of children. ..

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Amlosartan 5/160 Tab

Amlosartan 5/160 Tab

Indications Amlodipine and Valsartan combination is indicated for the treatment of hypertension. This fixed combination drug is not indicated for the initial therapy of hypertension Therapeutic Class Combined antihypertensive preparations Pharmacology Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II by selectively blocking the binding of Angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for Angiotensin II synthesis. Amlodipine and Valsartan have been shown to be effective in lowering blood pressure. Both Amlodipine and Valsartan lower blood pressure by reducing peripheral resistance, but calcium influx blockade and reduction of Angiotensin II vasoconstriction are complementary mechanisms. Dosage & Administration Amlodipine is an effective treatment of hypertension in once daily doses of 2.5 mg-10 mg while Valsartan is effective in doses of 80 mg-320 mg. In clinical trials with Amlodipine and Valsartan combination using Amlodipine doses of 5 mg-10 mg and Valsartan doses of 160 mg-320 mg, the antihypertensive effects increased with increasing doses. Interaction No drug interaction studies have been conducted with Amlodipine and Valsartan combination and other drugs, although studies have been conducted with the individual Amlodipine and Valsartan components Contraindications Amlodipine and Valsartan combination is contraindicated in patients who are hypersensitive to any compounds of this product. Side Effects The most common side effects include peripheral edema, vertigo, nasopharyngitis, upper respiratory tract infection and dizziness. Pregnancy & Lactation Pregnancy: Amlodipine and Valsartan combination should not be used in 2nd and 3rd trimester because it can cause fetal death .Nursing Mothers: It is not known whether Valsartan and Amlodipine are excreted in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother. Precautions Amlosartan should be used with caution because there is a risk for fetal or neonatal morbidity, hypotension, myocardial infarction or increased angina.Dose should be titrated slowly in patients with impaired hepatic or severely impaired renal function. In general, calcium channel blockers should be used with caution in patients with heart failure. Overdose Effects Limited data of human overdosage have been reported. Use in Special Population Pediatric use: The safety and effectiveness has not been established in pediatric patients.Geriatric use: No differences in overall incidence of adverse events were observed in elderly.Renal impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment. Titrate slowly in patients with severe renal impairment. Hepatic impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency. Titrate slowly in patients with hepatic impairment. Storage Conditions Store in a cool dry place protected from light. Keep out of reach of children. ..

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Amlosartan 5/80 Tab

Amlosartan 5/80 Tab

Amlosartan 5/80 TabPresentationAmlosartan 5/80: Each tablet contains Amlodipine Besilate BP equivalent to Amlodipine 5 mg & Valsartan USP 80 mg.DescriptionAmlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Amlodipine has a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure.Valsartan is an oral medication that belongs to a class of drugs called angiotensin receptor blockers (ARBs). It is orally active and specific angiotensin II antagonist acting on the AT1 subtype. Angiotensin's attachment to the receptors causes the blood vessels to narrow (vasoconstrict) which leads to an increase in blood pressure (hypertension). Valsartan blocks the angiotensin II receptor. By blocking the action of angiotensin, Valsartan dilates blood vessels and reduces blood pressure without affecting pulse rate. Valsartan has much greater affinity (about 20,000-fold) for the AT1 receptor than for the AT2 receptor. It does not bind or block other hormone receptors or ion channels known to be important in cardiovascular regulation.IndicationsAmlosartan is indicated for the treatment of hypertension. This combination drug is not indicated for the initial therapy of hypertension.Dosage & AdministrationAmlodipine is an effective treatment of hypertension in once daily doses of 2.5 mg to 10 mg while Valsartan is effective in doses of 80 mg to 320 mg. The majority of the antihypertensive effect is attained within 2 weeks after initiation of therapy or a change in dose. The dosage can be increased after 1 to 2 weeks of therapy to a maximum of one 10/320 mg tablet once daily as needed to control blood pressure.Amlosartan may be administered with or without food. Amlosartan may be administered with other antihypertensive agents. A patient whose blood pressure is not adequately controlled with Amlodipine alone or with Valsartan alone may be switched to their combination therapy.Elderly patients: Because of decreased clearance of Amlodipine, therapy should usually be initiated at 2.5 mg.Renal impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment. Titrate slowly in patients with severe renal impairment.Hepatic impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency. Titrate slowly in patients with hepatic impairment.Side EffectsThe most common side effects include peripheral edema, vertigo, nasopharyngitis, upper respiratory tract infection and dizziness.PrecautionsAmlosartan should be used with caution because there is a risk for-fetal or neonatal morbidityhypotensionmyocardial infarction or increased anginaDose should be titrated slowly in patients with impaired hepatic or severely impaired renal function. In general, calcium channel blockers should be used with caution in patients with heart failure.Use in Pregnancy & LactationPregnancy: Amlodipine and Valsartan combination should not be used in 2nd and 3rd trimester because it can cause fetal death .Nursing Mothers: It is not known whether Valsartan and Amlodipine are excreted in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.Over DoseLimited data of human overdosage have been reported.Commercial PackAmlosartan 5/80: Each box contains 3 alu-alu blister strips of 10 tablets...

Tk.6.00/=

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Anacaine HC cream

Anacaine HC cream

Indications Hydrocortisone plus Lidocaine cream is used for the anti-inflammatory and anesthetic relief of itching, pain, soreness and discomfort due to hemorrhoids, anal fissures, pruritus ani and similar conditions of the anal area. Therapeutic Class Drugs used in Ano-rectal region Pharmacology Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.Lidocaine is an amide type local anesthesia. It stabilises the neuronal membrane and inhibits Na ion movements, which are necessary for conduction of impulses. In the heart, lidocaine reduces depolarisation of the ventricles during diastole and automaticity in the His-Purkinje system. Duration of action potential and effective refractory period are also reduced. Dosage & Administration Apply twice daily around the anal opening in a thin layer using an applicator. Interaction This cream should be used with caution together with dental injection anaesthesia, other local anaesthetics or agents structurally related to local anaesthetics of amide type eg, antiarrhythmic drugs (eg, mexiletine), as the toxic effects of these drugs are additive.Patients treated with class III antiarrhythmic drugs (eg, amiodarone) should be closely observed and ECG monitoring should be considered, as the cardiac effects of lidocaine and class III antiarrhythmic drugs can be additive.Drugs that inhibit the metabolism of lidocaine (eg, cimetidine or ?-blockers) may cause potentially toxic plasma concentrations when lidocaine is given in repeated high doses over a long time period. Such interactions are of no clinical importance following short-term treatment with lidocaine at recommended doses. Contraindications Patients with a history of hypersensitivity to any of its ingredients. Side Effects Side effects like Rectal bleeding, Swelling of the skin, Adrenal suppression, Anaphylaxis, Angioedema, Cushing syndrome, Hirsutism, Acne, Cutaneous and subcutaneous atrophy, Dry scaly skin, Urticaria. Pregnancy & Lactation Pregnancy Category C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risksLactation: Unknown if distributed in breast milk; exercise caution Precautions If extensive areas are treated, the possibility of systemic absorption exists. Systemic absorption of topical steroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glycosuria in some patients. If irritation or sensitivity occurs or infection appears, discontinue use and institute appropriate therapy. ..

Tk.100.00/=

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Aprima 10mg Tablet

Aprima 10mg Tablet

Indications Apremilast is indicated for the treatment of adult patients with active psoriatic arthritis and moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. Therapeutic Class Disease-modifying antirheumatic drugs (DMARDs) Pharmacology Apremilast is a novel, orally available small molecule inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4). PDE-4 is a cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase that is predominantly located in inflammatory cells. By inhibiting PDE-4, apremilast increases intracellular levels of cAMP and thereby inhibits the production of multiple proinflammatory mediators including PDE-4, TNF-alpha, interleukin-2 (IL-2), interferon-gamma, leukotrienes, and nitric oxide synthase. By targeting a central component of the inflammatory signaling cascade rather than a single inflammatory marker, PDE-4 inhibition may restore the homeostatic balance between pro- and anti-inflammatory signalling. Dosage & Administration The recommended initial dosage titration of Apremilast from Day 1 to Day 5 is shown below. Following the 5-day titration, the recommended maintenance dosage is 30 mg twice daily taken orally starting on Day 6. This titration is intended to reduce the gastrointestinal symptoms associated with initial therapy. Apremilast can be administered without regard to meals.Day 1: 10 mg in morningDay 2: 10 mg in morning and 10 mg in evening Day 3: 10 mg in morning and 20 mg in evening Day 4: 20 mg in morning and 20 mg in evening Day 5: 20 mg in morning and 30 mg in evening Day 6: 30 mg twice dailyDosage adjustment in patients with severe renal impairment. Apremilast dosage should be reduced to 30 mg once daily in patients with severe renal impairment. For initial dosage titration, it is recommended that Apremilast be titrated using only the morning schedule and the evening doses be skipped. Interaction Co-administration of strong cytochrome P450 enzyme inducer Rifampin resulted in a reduction of systemic exposure of Apremilast.Therefore.the use of cytochrome P450 enzyme inducers (e.g. Rifampin, Phenobarbital,Carbamazepine, Phenytoin) with Apremilast is not recommended. Contraindications Apremilast is contraindicated in patients with a known hypersensitivity to Apremilast or to any of the excipients in the formulation. Side Effects The most frequently occurring side effects of Apremilast are nausea, diarrhea and headache. Other less frequent side effects are upper respiratory tract infection, vomiting, naospharyngitis, abdominal pain, hypersensitivity, gastroesophageal reflux disease, dyspepsia, fatigue, decrease appetite, cough, rash, insomnia. Pregnancy & Lactation Pregnancy Category C. It is not known whether Apremilast or its metabolites are present in human milk; however, Apremilast was detected in milk of lactating mice. Caution should be exercised when Apremilast is administered to a nursing woman. Precautions Treatment with Apremilast is associated with an increase in adverse reactions of depression. Patients, their caregivers and families should be advised of the need to be alert for the emergence or worsening of depression, suicidal thoughts or other mood changes and if such changes occur to contact their healthcare provider. Prescribers should carefully evaluate the risks and benefits of continuing treatment with Apremilast if such events occur.During the controlled period of the studies in psoriatic arthritis, weight decrease between 5-10% of body weight was reported in 10% of subjects treated with Apremilast 30 mg twice daily compared to 3.3% treated with placebo. Use in Special Population Use in Paediatric patient: The safety and effectiveness of Apremilast in paediatric patients less than 18 years of age have not been established. ..

Tk.25.00/=

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Aqualax powder for solution.

Aqualax powder for solution.

Indications Polyethylene Glycol is indicated in the treatment of constipation. This should be used for 2 weeks or less or as directed by physician. Polyethylene Glycol 3350 is a prescription only laxative that has been prescribed by physician to treat constipation. This product should only be used by the person for whom it is prescribed. Therapeutic Class Osmotic purgatives Description This is white powder for reconstitution. It is a synthetic polyglycol having an average molecular weight of 3350. Polyethylene Glycol is an osmotic agent that causes water to be retained with the stool. Polyethylene Glycol appears to have no effect on the active absorption or secretion of glucose or electrolytes. Pharmacology The primary mode of action is thought to be through the osmotic effect of polyethylene glycol 3350 which causes water to be retained in the colon and produces a watery stool. Polyethylene Glycol induces as diarrhea which rapidly cleanses the bowel, usually within four hours. Dosage The usual dose of Polyethylene Glycol is 17 gm of powder per day (or as directed by physician) in a glass of water, juice, coke, coffee or tea. Each bottle of Polyethylene Glycol is supplied with a cup that is used to measure 17 gm or 8.5 gm of laxative powder when filled upto the marked line. Administration It should always be taken by mouth. Measure the dose using the supplied cup, stir and dissolve in a glass of water, juice, coke, coffee or tea. Taking more than the prescribed dose may cause loss of fluid due to severe diarrhea. Interaction No specific drug interactions have been demonstrated. Contraindications Polyethylene glycol is contraindicated in patients with known or suspected bowel obstruction and patients known to be allergic to polyethylene glycol. Side Effects Nausea, abdominal bloating, cramping and flatulence may occur. High doses may produce diarrhea and excessive stool frequency, particularly in elderly nursing home patients. Patients taking other medications containing polyethylene glycol have occasionally developed urticaria suggestive of an allergic reaction. Pregnancy & Lactation Pregnancy: It is not known whether Polyethylene glycol can cause fetal harm when administered to a pregnant woman, or can effect reproductive capacity. Polyethylene glycol should only be administered to a pregnant woman if clearly needed.Lactation: There is no information on the use of Polyethylene glycol while nursing. Consultation with a physician is necessary in case of breastfeeding. Precautions Patients with symptoms suggestive of bowel obstruction (nausea, vomiting, abdominal pain or distention) should be evaluated to rule out this condition before initiating Polyethylene Glycol therapy. Polyethylene Glycol should be administered after being dissolved in water, juice, coke, coffee or tea. Overdose Effects There have been no reports of accidental overdosage. In the event of overdosage diarrhea would be the expected major event. If an overdose of drug occurred without concomitant ingestion of fluid, dehydration due to diarrhea may result. Medication should be terminated and free water administered. Duration of Treatment Polyethylene Glycol achieves its best results when used between one and two weeks. It may be discontinued after several satisfactory bowel movements. Should unusual cramps, bloating, or diarrhea occur, consultation with physician is needed. Polyethylene Glycol is intended for up to a two-week course of therapy. It should not be used for a longer time unless directed by a physician. After successfully completing the Polyethylene Glycol therapy (usually between one and two weeks) discussion with a physician is needed to change lifestyle ..

Tk.120.00/=

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Aripra 10 Tablet

Aripra 10 Tablet

Indications Aripiprazole is indicated for- SchizophreniaSchizoaffective disorderAcute manic and mixed episodes associated with Bipolar I DisorderMaintaining efficacy in patients with Bipolar I Disorder who are stabilized Therapeutic Class Atypical neuroleptic drugs Pharmacology Aripiprazole is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms. Dosage & Administration For Schizophrenia: 10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.For Bipolar mania: 30 mg, once daily, without regard to food. Interaction Caution should be exercised when aripipazole is taken in combination with other centrally acting drugs and alcohol. Carbamazepine could cause an increase in aripiprazole clearance and lower blood levels. Ketoconazole, quinidine, fluoxetine or paroxetine can inhibit aripiprazole elimination and cause increased blood levels. Contraindications Aripiprazole is contraindicated in patients who are hypersensitive to it or to any component of this product. Side Effects Headache, constipation, asthenia, nausea, dyspepsia, vomiting, coughing, abdominal pain. Pregnancy & Lactation Aripiprazole should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast feed an infant if they are taking aripiprazole. Precautions Aripiprazole may be associated with orthostatic hypotension (orthostatic lightheadedness).Aripiprazole should be used with caution in patients with known cardiovascular disease (myocardial infarction or ischaemic heart disease, heart failure or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications).Seizures occurred in aripiprazole-treated patients. As with other antipsychotic drugs, aripiprazole should be used cautiously in patients with Alzheimer's dementia.Aripiprazole is not approved for the treatment of patients with dementia-related psychosis. Overdose Effects Aripiprazole at doses up to 1080 mg causes no fatalities. The signs and symptoms observed with aripiprazole overdose included nausea, vomiting, asthenia, diarrhea, and somnolence. ..

Tk.5.00/=

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Aripra 15 Tab

Aripra 15 Tab

Aripra 15 TabPresentationAripra 15: Each tablet contains Aripiprazole INN 15 mg.DescriptionAripra (Aripiprazole) is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms.IndicationsSchizophreniaSchizoaffective disorderAcute manic and mixed episodes associated with Bipolar I DisorderMaintaining efficacy in patients with Bipolar I Disorder who are stabilizedDosage & AdministrationFor Schizophrenia:Adults-10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.For Bipolar mania:Adults- 30 mg, once daily, without regard to food.Side EffectsHeadache, constipation, asthenia, nausea, dyspepsia, vomiting, coughing, abdominal pain.PrecautionsAripiprazole may be associated with orthostatic hypotension (orthostatic lightheadedness).Aripiprazole should be used with caution in patients with known cardiovascular disease (myocardial infarction or ischaemic heart disease, heart failure or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications).Seizures occurred in aripiprazole-treated patients. As with other antipsychotic drugs, aripiprazole should be used cautiously in patients with Alzheimer\\\'s dementia.Aripiprazole is not approved for the treatment of patients with dementia-related psychosis.Use in Pregnancy & LactationAripiprazole should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast-feed an infant if they are taking aripiprazole.Drug InteractionCaution should be exercised when aripipazole is taken in combination with other centrally acting drugs and alcohol. Carbamazepine could cause an increase in aripiprazole clearance and lower blood levels. Ketoconazole, quinidine, fluoxetine or paroxetine can inhibit aripiprazole elimination and cause increased blood levels.Over DoseAripiprazole at doses up to 1080 mg causes no fatalities. The signs and symptoms observed with aripiprazole overdose included nausea, vomiting, asthenia, diarrhea, and somnolence.Commercial PackAripra 15: Each box contains 5 blister strips of 10 tablets...

Tk.7.00/=

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Aritone Z  tablet

Aritone Z tablet

Aritone Z..

Tk.3.00/=

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Arofil 200 SR Tab

Arofil 200 SR Tab

Arofil 200 SR TabPresentationArofil 200 SR: Each film coated tablet contains Theophylline BP 200 mg in a sustained release formulation.DescriptionTheophylline is a Xanthine derivative bronchodilator; it directly relaxes the smooth muscle of the bronchial airways and smooth pulmonary blood vessels, thus acting mainly as a bronchodilator and smooth muscle relaxant.Indications1) Control of acute asthma2) Management of chronic asthma (For both Symptomatic and prophylactic treatment)3) For controlling nocturnal asthma and early morning wheezing4) Management of chronic obstructive lung disease (Chronic bronchitis and emphysema) and acute exacerbation of chronic obstructive lung disease5) Control of apnea of pre-maturityDosage & AdministrationUsually Arofil SR tablet 12 hourly or as directed by the physicians.Age Dose/day in bid1-9 years 24 mg/kg9-12 years 20 mg/kg12-16 years 18 mg/kgOver 16 years 13 mg/kg or 900 mgSide EffectsThese usually occur when Theophylline blood levels exceed 20 mgm/ml and include gastric irritation, nausea, vomiting, abdominal discomfort and palpitations, a fall in blood pressure, headache, occasional diarrhoea and insomnia. CNS stimulation and diuresis may also occur, especially in children.PrecautionsSmoking and alcohol consumption can increase the clearance of Theophylline and a higher dosage may be necessary.Careful monitoring is recommended for patients with congestive heart failure, chronic alcoholism, hepatic dysfunction or viral infections as they may have lower total clearance of Theophylline which could lead to higher than normal plasma levels.Caution should be exercised in patients with hyperthyroidism, cardiac arrhythmia, hypertension or other cardiovascular diseases.Use in Pregnancy & LactationSafety in human pregnancy has not been established. Theophylline crosses the placental barrier & is secreted in breast milk. Theophylline should be used with caution in pregnancy & lactation.Over DoseSymptoms may include nausea, vomiting, gastrointestinal irritation, cramps, convulsions, tachycardia & hypotension. The stomach contents should be emptied & supportive measures employed to maintain circulation, respiration & fluid & electrolyte balance. Electrocardiographic monitoring should be carried out & in severe poisoning charcoal haemoperfusion should be used.Commercial PackArofil 200 SR: Each box contains 10 blister strips of 10 sustained release tablets...

Tk.1.60/=

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Arofil SR 300 Tab

Arofil SR 300 Tab

Arofil SR 300 TabPresentationArofil 300 SR: Each film coated tablet contains Theophylline BP 300 mg in a sustained release formulation.DescriptionTheophylline is a Xanthine derivative bronchodilator; it directly relaxes the smooth muscle of the bronchial airways and smooth pulmonary blood vessels, thus acting mainly as a bronchodilator and smooth muscle relaxant.Indications1) Control of acute asthma2) Management of chronic asthma (For both Symptomatic and prophylactic treatment)3) For controlling nocturnal asthma and early morning wheezing4) Management of chronic obstructive lung disease (Chronic bronchitis and emphysema) and acute exacerbation of chronic obstructive lung disease5) Control of apnea of pre-maturityDosage & AdministrationUsually Arofil SR tablet 12 hourly or as directed by the physicians.Age Dose/day in bid1-9 years 24 mg/kg9-12 years 20 mg/kg12-16 years 18 mg/kgOver 16 years 13 mg/kg or 900 mgSide EffectsThese usually occur when Theophylline blood levels exceed 20 mgm/ml and include gastric irritation, nausea, vomiting, abdominal discomfort and palpitations, a fall in blood pressure, headache, occasional diarrhoea and insomnia. CNS stimulation and diuresis may also occur, especially in children.PrecautionsSmoking and alcohol consumption can increase the clearance of Theophylline and a higher dosage may be necessary.Careful monitoring is recommended for patients with congestive heart failure, chronic alcoholism, hepatic dysfunction or viral infections as they may have lower total clearance of Theophylline which could lead to higher than normal plasma levels.Caution should be exercised in patients with hyperthyroidism, cardiac arrhythmia, hypertension or other cardiovascular diseases.Use in Pregnancy & LactationSafety in human pregnancy has not been established. Theophylline crosses the placental barrier & is secreted in breast milk. Theophylline should be used with caution in pregnancy & lactation.Over DoseSymptoms may include nausea, vomiting, gastrointestinal irritation, cramps, convulsions, tachycardia & hypotension. The stomach contents should be emptied & supportive measures employed to maintain circulation, respiration & fluid & electrolyte balance. Electrocardiographic monitoring should be carried out & in severe poisoning charcoal haemoperfusion should be used.Commercial PackArofil 300 SR: Each box contains 5 blister strips of 10 sustained release tablets...

Tk.2.35/=

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Arofil SR 400 Tab

Arofil SR 400 Tab

Arofil SR 400 TabPresentationArofil 400 SR: Each film coated tablet contains Theophylline BP 400 mg in a sustained release formulation.DescriptionTheophylline is a Xanthine derivative bronchodilator; it directly relaxes the smooth muscle of the bronchial airways and smooth pulmonary blood vessels, thus acting mainly as a bronchodilator and smooth muscle relaxant.Indications1) Control of acute asthma2) Management of chronic asthma (For both Symptomatic and prophylactic treatment)3) For controlling nocturnal asthma and early morning wheezing4) Management of chronic obstructive lung disease (Chronic bronchitis and emphysema) and acute exacerbation of chronic obstructive lung disease5) Control of apnea of pre-maturityDosage & AdministrationUsually Arofil SR tablet 12 hourly or as directed by the physicians.Age Dose/day in bid1-9 years 24 mg/kg9-12 years 20 mg/kg12-16 years 18 mg/kgOver 16 years 13 mg/kg or 900 mgSide EffectsThese usually occur when Theophylline blood levels exceed 20 mgm/ml and include gastric irritation, nausea, vomiting, abdominal discomfort and palpitations, a fall in blood pressure, headache, occasional diarrhoea and insomnia. CNS stimulation and diuresis may also occur, especially in children.PrecautionsSmoking and alcohol consumption can increase the clearance of Theophylline and a higher dosage may be necessary.Careful monitoring is recommended for patients with congestive heart failure, chronic alcoholism, hepatic dysfunction or viral infections as they may have lower total clearance of Theophylline which could lead to higher than normal plasma levels.Caution should be exercised in patients with hyperthyroidism, cardiac arrhythmia, hypertension or other cardiovascular diseases.Use in Pregnancy & LactationSafety in human pregnancy has not been established. Theophylline crosses the placental barrier & is secreted in breast milk. Theophylline should be used with caution in pregnancy & lactation.Over DoseSymptoms may include nausea, vomiting, gastrointestinal irritation, cramps, convulsions, tachycardia & hypotension. The stomach contents should be emptied & supportive measures employed to maintain circulation, respiration & fluid & electrolyte balance. Electrocardiographic monitoring should be carried out & in severe poisoning charcoal haemoperfusion should be used.Commercial PackArofil 400 SR: Each box contains 5 blister strips of 10 sustained release tablets...

Tk.2.98/=

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Arpolax 20 mg Tablet

Arpolax 20 mg Tablet

Arpolax 20 mg TabletPresentationArpolax tablet: Each tablet contains Citalopram Hydrobromide INN equivalent to Citalopram 20 mg.DescriptionCitalopram is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs, tricyclic, tetracyclic or other available antidepressant agents. The mechanism of action of Citalopram as an antidepressant is presumed to be linked to potentiation of serotonergic activity in central nervous system resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT).IndicationsCitalopram is indicated for depressive illness and panic disorder. It is also indicated in substance abuse disorders and alcohol dependence. Citalopram has also been given in variety of anxiety disorders including obsessive-compulsive disorder and social phobia. It is also effective in generalized anxiety disorder, post-traumatic stress disorder, premenstrual syndrome, idiopathic Parkinson's disease and eating disorder.Dosage & AdministrationDepressive illness 20 mg daily as a single dose in the morning or evening; increased ifnecessary to maximum 60 mg daily (Elderly maximum 40 mgdaily).Panic disorder Initially 10 mg daily, increased to 20 mg after 7 days; usual dose 20-30 mg daily; maximum 60 mg daily (Elderly maximum 40 mgdaily).Side EffectsSSRIs are less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants. However, side-effects may be seen, includes gastro-intestinal effects (nausea, vomiting, dyspepsia, abdominal pain, diarrhoea, constipation), anorexia with weight loss, palpitations, tachycardia, postural hypotension, cough, confusion, impaired concentration, amnesia, urinary retention, sweating, movement disorders, urticaria, anaphylaxis, arthralgia, myalgia and photosensitivity.PrecautionsCaution should be taken in patients with epilepsy, concurrent electroconvulsive therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, history of bleeding disorders, hepatic and renal impairment. Abrupt withdrawal of Citalopram should be avoided.Use in Pregnancy & LactationPregnancyThere are no adequate and well-controlled studies in pregnant women; therefore, Citalopram should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.LactationCitalopram is excreted in human breast milk. So, the decision whether to continue or discontinue either nursing or Citalopram therapy should take into account the risks of Citalopram exposure for the infants and the benefits of Citalopram treatment for the mother.Drug InteractionKetoconazole, Itraconazole or Macrolide antibiotics and Citalopram co-administration decreases the metabolism of Citalopram. Omeprazole and Citalopram co-administration might decrease the clearance of Citalopram.Over DoseIt is a very safe drug. There were no reports of fatal Citalopram overdose in clinical trials involving overdoses of up to 2000 mg.Commercial PackArpolax tablet: Box containing 3 blister strips of 10 tablets...

Tk.8.00/=

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Artemet Tablet

Artemet Tablet

Artemet 20 mg+120 mg TabletPresentationArtemet: Each tablet contains Artemether INN 20 mg and Lumefantrine INN 120 mg.DescriptionThis formulation contains a fixed ratio of 1 : 6 parts of Artemether and Lumefantrine. The site of antiparasitic action of both components is the food vacuole of the malarial parasite, where they are thought to interfere with the conversion of haem, a toxic intermediate produced during haemoglobin breakdown, to the non-toxic haemozoin (malaria pigment). Lumefantrine is thought to interfere with the polymerisation process, while Artemether generates reactive metabolites as a result of the interaction between its peroxide bridge and haem iron. Both Artemether and Lumefantrine have a secondary action involving inhibition of nucleic acid and protein synthesis within the malarial parasite.IndicationsArtemether-Lumefantrine is indicated in the treatment of adults, children and infants with acute, uncomplicated infections due to Plasmodium falciparum or mixed infections including P. falciparum. Because this combination is effective against both drug-sensitive and drug-resistant P. falciparum, it is also recommended for malaria infections acquired in areas where the parasites may be resistant to other antimalarials.Stand-by emergency treatment: Prescribers are advised to issue Artemether-Lumefantrine combination (to be carried for self-administration) to those tourists and business travelers who are considered to be non-immune and may be unable to obtain medical care within 24 hours of the onset of symptoms of malaria.Dosage & AdministrationThe treatment should be administered at the time of initial diagnosis or at onset of symptoms. This combination should be taken with food or drinks rich in fat (such as milk). The treatment schedule is as follows:Patient TypeFrist daySecond dayThird dayChildren (weighing 5 kg to less than 15 kg)1 tablet at the time of initial diagnosis, 1 tablet again after 8 hours1 tablet twice daily (morning and evening)1 tablet twice daily (morning and evening)Children (weighing 15 kg to less than 25 kg and 12 years of age or less)2 tablets as a single dose at the time of initial diagnosis, 2 tablets again after 8 hours2 tablets twice daily (morning and evening)2 tablets twice daily (morning and evening)Children (weighing 25 kg to less than 35 kg and 12 years of age or less)3 tablets as a single dose at the time of initial diagnosis, 3 tablets again after 8 hours3 tablets twice daily (morning and evening)3 tablets twice daily (morning and evening)Adults and children (weighing 35 kg and above or more than 12 years of age)4 tablets as a single dose at the time of initial diagnosis, 4 tablets again after 8 hours4 tablets twice daily (morning and evening)4 tablets twice daily (morning and evening)Side EffectsThis formulation is generally well tolerated. However, few side effects such as anorexia, headache, dizziness, sleep disorder, palpitation, pruritus, rash, abdominal pain, nausea and vomiting have been reported.PrecautionsIf a patient deteriorates whilst taking this combination, alternative treatment for malaria should be started without delay. The long elimination half-life of Lumefantrine must be taken into account when administering quinine in patients previously treated with this combination. This combination has not been evaluated for: prophylaxis; treatment of cerebral malaria; treatment of severe malaria including pulmonary oedema or renal failure; treatment of malaria due to P. vivax, P. malariae or P. ovale.Use in Pregnancy & LactationPregnancy: Based on animal data, this combination is suspected to cause serious birth defects during the first trimester of pregnancy. Artemether has demonstrated teratogenic potential with an increased risk during early gestation. This combination is contraindicated during the first trimester of pregnancy. During the second and the third trimester, treatment should only be considered if the expected benefit to the mother outweighs the risk to the foetus.Lactation: Breast-feeding women should not take Artemether-Lumefantrine combination.Drug InteractionDose adjustment of Artemether-Lumefantrine is considered unnecessary when administered in association with ketoconazole. The likelihood of interactions with other drugs is minimal in view of its short duration of administration and wide therapeutic index. From study it was found that, the risk of QTc-prolongation associated with IV quinine was enhanced by prior administration of this combination.Over DoseIn cases of suspected overdosage, symptomatic and supportive therapy should be given as appropriate. ECG and electrolytes (e.g. potassium) should be monitored.Commercial PackArtemet: Each box contains 6 Alu-Alu blister strip of 4 tablets...

Tk.20.00/=

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Askorel 100 ml Syp

Askorel 100 ml Syp

Askorel 100 ml SypIndicationsAskorel is indicated in acute cough of any etiology, suppression of pre-& post-operative cough in surgery & bronchoscopy and suppression of whooping cough.Dosage & AdministrationDosage formAgeDoseSRTabletAdolescents over 12 years1-2 tablets dailyAdults2-3 tablets daily at 8-12 hoursintervalSyrupInfants (2 months - 1 year)1.5 ml four times dailyInfants (1 - 3 years)2.5 ml four times dailyChildren 3-5 years of age7.5 ml three times daily> 6 years and adults15 ml three times dailyPaediatricdropsInfants (2 months - 1 year)10 drops four times dailyInfants (1 - 3 years)15 drops four times dailySide EffectsTolerance of Butamirate Citrate is good. Adverse reactions such as rash, nausea, diarrhea and vertigo have been observed in a few rare cases, resolving after dose reduction or treatment withdrawal.PrecautionsNot applicableUse in Pregnancy & LactationButamirate Citrate should not be used during the first trimester of pregnancy. During the remainder of pregnancy, it can be used if indicated by a physician but with caution. As a general rule, for safety reasons, in the absence of data on elimination of the active substance in breast milk, the benefits of Butamirate Citrate administration during breast feeding should be carefully weighed against the risks.Over DoseAccidental overdose with Butamirate Citrate can cause the following symptoms: drowsiness, nausea, vomiting, diarrhea, loss of balance and hypotension. Standard emergency procedures should be followed: activated charcoal, saline laxatives and standard cardio-respiratory resuscitation.StorageDo not store above 30 0 C. Keep away from light and out of the reach of children...

Tk.80.00/=

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Askorel SR Tab

Askorel SR Tab

Askorel SR TabIndicationsAskorel is indicated in acute cough of any etiology, suppression of pre-& post-operative cough in surgery & bronchoscopy and suppression of whooping cough.Dosage & AdministrationDosage formAgeDoseSRTabletAdolescents over 12 years1-2 tablets dailyAdults2-3 tablets daily at 8-12 hoursintervalSyrupInfants (2 months - 1 year)1.5 ml four times dailyInfants (1 - 3 years)2.5 ml four times dailyChildren 3-5 years of age7.5 ml three times daily> 6 years and adults15 ml three times dailyPaediatricdropsInfants (2 months - 1 year)10 drops four times dailyInfants (1 - 3 years)15 drops four times dailySide EffectsTolerance of Butamirate Citrate is good. Adverse reactions such as rash, nausea, diarrhea and vertigo have been observed in a few rare cases, resolving after dose reduction or treatment withdrawal.PrecautionsNot applicableUse in Pregnancy & LactationButamirate Citrate should not be used during the first trimester of pregnancy. During the remainder of pregnancy, it can be used if indicated by a physician but with caution. As a general rule, for safety reasons, in the absence of data on elimination of the active substance in breast milk, the benefits of Butamirate Citrate administration during breast feeding should be carefully weighed against the risks.Over DoseAccidental overdose with Butamirate Citrate can cause the following symptoms: drowsiness, nausea, vomiting, diarrhea, loss of balance and hypotension. Standard emergency procedures should be followed: activated charcoal, saline laxatives and standard cardio-respiratory resuscitation.StorageDo not store above 30 0 C. Keep away from light and out of the reach of children...

Tk.10.00/=

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Azecol Cap

Azecol Cap

Azecol CapIndicationsPrimary use: Eye health.Secondary uses: Antioxidant, Immune system support.Dosage & AdministrationOne capsule daily. In more severe cases, 2 capsules a day may be required or as directed by the physician.Side EffectsGenerally well tolerated. However, a few allergic reactions may be seen. Diarrhea and other gastrointestinal disturbances may occur.PrecautionsCaution should be taken during the concomitant use of anticoagulant.Use in Pregnancy & LactationRecommended.Drug InteractionNo such drug interactions have been reported.StorageStore in a dry place below 25° C. Protect from light...

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AztaCap 4 mg Capsule

AztaCap 4 mg Capsule

AztaCap 4 mg CapsuleDescriptionAstaxanthin acts as an antioxidant by dual mode of action. It suppresses singlet oxygen and also inhibits lipid peroxidation. By these actions it reduces the harmful free radicals. Therefore acts as a very strong antioxidant. Astaxanthin is absorbed by passive diffusion into the intestinal epithelium alongside fatty acids. Then it is incorporated into lipoproteins, transported to the liver, via lymph and blood and partly resecreted with lipoproteins. More than 70% of the Astaxanthin is contained in high-density lipoprotein part of plasma. Highest concentration of Astaxanthin is in the small intestine, followed by subcutaneous fat, spleen, liver, heart, kidney and skin and lowest in the muscles.IndicationsAstaxanthin is indicated to-1. Strong antioxidant2. Improves cardiovascular health (Atherosclerosis, reduce cholesterol).3. Improves immune function.4. Improves condition of skin5. Protects skin from damage caused by sun (Reduce wrinkles, pimples and other signs of aging)6. Improves recovery from central nervous system injuries7. Protects from Parkinson ’s disease, Dementia and Alzheimer\'s8. Protects eyes from cataracts and macular degeneration.9. Reduces inflammation (Arthritis)10. Reduces risk of infertilityAlso Astaxnthin effectively reduce oxidative damage to DNA, decrease the risk for many types of cancer and stabilize blood sugar.Dosage & AdministrationAdults (18 years and older) - Daily dose is 4mg. should be taken along with or immediately prior to meals in the morning.Different dose for various use are given below:4 mg: Used as a strong antioxidant, improves cardiovascular health (Atherosclerosis, reduce cholesterol), improves immune function.4-8 mg: Improves condition of skin, protects skin from sun damage (Reduce wrinkles, pimples and other signs of aging), improves recovery from central nervous system injuries and protects eyes from cataracts and macular degeneration.8-12 mg: Reduces inflammation (Arthritis)16 mg: Reduces risk of infertilitySide EffectsNo severe side effects have been reported yetPrecautionsN/AUse in Pregnancy & LactationBoth pregnant women and lactating mothers should avoid Astaxanthin supplements as no data on safety has been found yetDrug InteractionConcomitant intake of Astaxanthin with Cholestyramine, Colestipol, Mineral oil, Orlistat may reduce the absorption rate of AstaxanthinOver DoseNo case of overdose has occurred with AstaxanthinStorageStore in cool and dry place, away from direct light. Keep out of reach of children..

Tk.22.00/=

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Barbit 30 mg tab

Barbit 30 mg tab

Barbit 30 mg tabDescriptionBarbit is a preparation of Phenobarbital which is a barbiturate, nonselective, central nervous system depressant which is primarily used as a sedative hypnotic and also as an anticonvulsant in subhypnotic doses.IndicationsBarbit is indicated for the following conditions:SedativesHypnotics for the short-term treatment of insomniaPre-anestheticsLong-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures. And, in the emergency control of certain acute convulsive episodes, ( those associated with status epilepticus, eclampsia meningitis, tetanus, and toxic reactions to Strychnine or local anesthetics).Dosage & AdministrationSuggested doses of Phenobarbital for specific indications are as follows:a. Pediatric Oral Dosage:Preoperative: 1 mg to 3 mg/kg.Anticonvulsant: 1 mg to 6 mg/kg per dayb. Adult Oral Dosage:1. Daytime sedative: 30 mg to 120 mg daily in 2 to 3 divided doses.2. Bedtime hypnotic: 100 mg to 320 mg.3. Anticonvulsant: 50 mg to 100 mg 2 to 3 times daily.Side EffectsThe most common adverse reaction is somnolence. Other less frequent adverse reactions are agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thinking abnormality, apnea, bradycardia, hypotension, nausea, vomiting and constipation.PrecautionsTolerance and psychological and physical dependence may occur with continuing use. Phenobarbital should be administered with caution to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse. In patients with hepatic damage, Phenobarbital should be administered with caution and initially reduced doses.Use in Pregnancy & LactationPregnancy Category D. Phenobarbital can cause fetal damage when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be in risk of the potential hazard to the fetus. Caution should be taken when Phenobarbital is administered to a nursing woman since small amounts of Phenobarbital are excreted in the milk.Drug InteractionThe concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects.Over DoseThe toxic dose of barbiturates varies considerably. In general, an oral dose of 1 gram of most barbiturates produces serious poisoning in an adult. Death commonly occurs after 2 to 10 grams of ingested barbiturate. Acute overdosage with barbiturates is manifested by CNS and respiratory depression Treatment of overdosage is mainly supportive and immediate hospitaslization is necessary...

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Barbit 60 mg Tab

Barbit 60 mg Tab

Barbit 60 mg TabDescriptionBarbit is a preparation of Phenobarbital which is a barbiturate, nonselective, central nervous system depressant which is primarily used as a sedative hypnotic and also as an anticonvulsant in subhypnotic doses.IndicationsBarbit is indicated for the following conditions:SedativesHypnotics for the short-term treatment of insomniaPre-anestheticsLong-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures. And, in the emergency control of certain acute convulsive episodes, ( those associated with status epilepticus, eclampsia meningitis, tetanus, and toxic reactions to Strychnine or local anesthetics).Dosage & AdministrationSuggested doses of Phenobarbital for specific indications are as follows:a. Pediatric Oral Dosage:Preoperative: 1 mg to 3 mg/kg.Anticonvulsant: 1 mg to 6 mg/kg per dayb. Adult Oral Dosage:1. Daytime sedative: 30 mg to 120 mg daily in 2 to 3 divided doses.2. Bedtime hypnotic: 100 mg to 320 mg.3. Anticonvulsant: 50 mg to 100 mg 2 to 3 times daily.Side EffectsThe most common adverse reaction is somnolence. Other less frequent adverse reactions are agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thinking abnormality, apnea, bradycardia, hypotension, nausea, vomiting and constipation.PrecautionsTolerance and psychological and physical dependence may occur with continuing use. Phenobarbital should be administered with caution to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse. In patients with hepatic damage, Phenobarbital should be administered with caution and initially reduced doses.Use in Pregnancy & LactationPregnancy Category D. Phenobarbital can cause fetal damage when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be in risk of the potential hazard to the fetus. Caution should be taken when Phenobarbital is administered to a nursing woman since small amounts of Phenobarbital are excreted in the milk.Drug InteractionThe concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects.Over DoseThe toxic dose of barbiturates varies considerably. In general, an oral dose of 1 gram of most barbiturates produces serious poisoning in an adult. Death commonly occurs after 2 to 10 grams of ingested barbiturate. Acute overdosage with barbiturates is manifested by CNS and respiratory depression Treatment of overdosage is mainly supportive and immediate hospitaslization is necessary...

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Barbit Elixir 100ml

Barbit Elixir 100ml

Barbit Elixir 100mlDescriptionBarbit is a preparation of Phenobarbital which is a barbiturate, nonselective, central nervous system depressant which is primarily used as a sedative hypnotic and also as an anticonvulsant in subhypnotic doses.IndicationsBarbit is indicated for the following conditions:SedativesHypnotics for the short-term treatment of insomniaPre-anestheticsLong-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures. And, in the emergency control of certain acute convulsive episodes, ( those associated with status epilepticus, eclampsia meningitis, tetanus, and toxic reactions to Strychnine or local anesthetics).Dosage & AdministrationSuggested doses of Phenobarbital for specific indications are as follows:a. Pediatric Oral Dosage:Preoperative: 1 mg to 3 mg/kg.Anticonvulsant: 1 mg to 6 mg/kg per dayb. Adult Oral Dosage:1. Daytime sedative: 30 mg to 120 mg daily in 2 to 3 divided doses.2. Bedtime hypnotic: 100 mg to 320 mg.3. Anticonvulsant: 50 mg to 100 mg 2 to 3 times daily.Side EffectsThe most common adverse reaction is somnolence. Other less frequent adverse reactions are agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thinking abnormality, apnea, bradycardia, hypotension, nausea, vomiting and constipation.PrecautionsTolerance and psychological and physical dependence may occur with continuing use. Phenobarbital should be administered with caution to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse. In patients with hepatic damage, Phenobarbital should be administered with caution and initially reduced doses.Use in Pregnancy & LactationPregnancy Category D. Phenobarbital can cause fetal damage when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be in risk of the potential hazard to the fetus. Caution should be taken when Phenobarbital is administered to a nursing woman since small amounts of Phenobarbital are excreted in the milk.Drug InteractionThe concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects.Over DoseThe toxic dose of barbiturates varies considerably. In general, an oral dose of 1 gram of most barbiturates produces serious poisoning in an adult. Death commonly occurs after 2 to 10 grams of ingested barbiturate. Acute overdosage with barbiturates is manifested by CNS and respiratory depression Treatment of overdosage is mainly supportive and immediate hospitaslization is necessary...

Tk.57.00/=

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Barbit Elixir 50ml

Barbit Elixir 50ml

Barbit Elixir 50mlDescriptionBarbit is a preparation of Phenobarbital which is a barbiturate, nonselective, central nervous system depressant which is primarily used as a sedative hypnotic and also as an anticonvulsant in subhypnotic doses.IndicationsBarbit is indicated for the following conditions:SedativesHypnotics for the short-term treatment of insomniaPre-anestheticsLong-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures. And, in the emergency control of certain acute convulsive episodes, ( those associated with status epilepticus, eclampsia meningitis, tetanus, and toxic reactions to Strychnine or local anesthetics).Dosage & AdministrationSuggested doses of Phenobarbital for specific indications are as follows:a. Pediatric Oral Dosage:Preoperative: 1 mg to 3 mg/kg.Anticonvulsant: 1 mg to 6 mg/kg per dayb. Adult Oral Dosage:1. Daytime sedative: 30 mg to 120 mg daily in 2 to 3 divided doses.2. Bedtime hypnotic: 100 mg to 320 mg.3. Anticonvulsant: 50 mg to 100 mg 2 to 3 times daily.Side EffectsThe most common adverse reaction is somnolence. Other less frequent adverse reactions are agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thinking abnormality, apnea, bradycardia, hypotension, nausea, vomiting and constipation.PrecautionsTolerance and psychological and physical dependence may occur with continuing use. Phenobarbital should be administered with caution to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse. In patients with hepatic damage, Phenobarbital should be administered with caution and initially reduced doses.Use in Pregnancy & LactationPregnancy Category D. Phenobarbital can cause fetal damage when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be in risk of the potential hazard to the fetus. Caution should be taken when Phenobarbital is administered to a nursing woman since small amounts of Phenobarbital are excreted in the milk.Drug InteractionThe concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects.Over DoseThe toxic dose of barbiturates varies considerably. In general, an oral dose of 1 gram of most barbiturates produces serious poisoning in an adult. Death commonly occurs after 2 to 10 grams of ingested barbiturate. Acute overdosage with barbiturates is manifested by CNS and respiratory depression Treatment of overdosage is mainly supportive and immediate hospitaslization is necessary...

Tk.29.06/=

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Barbit IV/IM inj

Barbit IV/IM inj

Barbit IV/IM injDescriptionBarbit is a preparation of Phenobarbital which is a barbiturate, nonselective, central nervous system depressant which is primarily used as a sedative hypnotic and also as an anticonvulsant in subhypnotic doses.IndicationsBarbit is indicated for the following conditions:SedativesHypnotics for the short-term treatment of insomniaPre-anestheticsLong-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures. And, in the emergency control of certain acute convulsive episodes, ( those associated with status epilepticus, eclampsia meningitis, tetanus, and toxic reactions to Strychnine or local anesthetics).Dosage & AdministrationSuggested doses of Phenobarbital for specific indications are as follows:a. Pediatric Oral Dosage:Preoperative: 1 mg to 3 mg/kg.Anticonvulsant: 1 mg to 6 mg/kg per dayb. Adult Oral Dosage:1. Daytime sedative: 30 mg to 120 mg daily in 2 to 3 divided doses.2. Bedtime hypnotic: 100 mg to 320 mg.3. Anticonvulsant: 50 mg to 100 mg 2 to 3 times daily.Side EffectsThe most common adverse reaction is somnolence. Other less frequent adverse reactions are agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thinking abnormality, apnea, bradycardia, hypotension, nausea, vomiting and constipation.PrecautionsTolerance and psychological and physical dependence may occur with continuing use. Phenobarbital should be administered with caution to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse. In patients with hepatic damage, Phenobarbital should be administered with caution and initially reduced doses.Use in Pregnancy & LactationPregnancy Category D. Phenobarbital can cause fetal damage when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be in risk of the potential hazard to the fetus. Caution should be taken when Phenobarbital is administered to a nursing woman since small amounts of Phenobarbital are excreted in the milk.Drug InteractionThe concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects.Over DoseThe toxic dose of barbiturates varies considerably. In general, an oral dose of 1 gram of most barbiturates produces serious poisoning in an adult. Death commonly occurs after 2 to 10 grams of ingested barbiturate. Acute overdosage with barbiturates is manifested by CNS and respiratory depression Treatment of overdosage is mainly supportive and immediate hospitaslization is necessary...

Tk.80.00/=

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Benadip 10/5 cap.

Benadip 10/5 cap.

Benadip 10/5 cap...

Tk.6.00/=

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Besiven Eye Drop

Besiven Eye Drop

Besiven Eye DropIndicationsThis drug is indicated for the treatment of bacterial conjunctivitis caused by susceptible isolates of the following bacteria:CDC coryneform group G, Corynebacterium pseudodiphtheriticum, Corynebacterium striatum, Haemophilus influenza, Moraxella lacunata, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis, Staphylococcus lugdunensis, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumonia, Streptococcus salivarius.Dosage & AdministrationAdults and children (1 year of age and older): Instill one drop in the affected eye(s) 3 times a day for 7 days.Side EffectsThe most frequently reported ocular adverse event was conjunctival redness, reported in approximately 2% of patients. Other adverse events reported in approximately 1-2% of patients included: blurred vision, eye pain, eye irritation, eye pruritus and headache.PrecautionsThis drug is for topical ophthalmic use only and should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye. As with other anti -infectives, prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue use and institute alternative therapy. To prevent contamination do not touch the tip of the dropper to eye, eyelid or any surface of the affected eye. Patients should not wear contact lenses during the course of therapy with this drug.Shake well before use.Use in Pregnancy & LactationPregnancy Category C. No adequate and women. This drug should be used during potential risk to the fetus. well-controlled studies are established in pregnant pregnancy only if the potential benefit justifies the It is not known whether Besifloxacin is secreted in human milk or not. Caution should be exercised when Besifloxacin is administered to a nursing mother.Drug InteractionNo information is available.Over DoseNo information is available.StorageStore in a cool, dry place and protected from light. Keep out of the reach of children. Discard the container 4 weeks after opening.Commercial PackBesiven Sterile Eye Drops: Each plastic dropper bottle contains 5ml of sterile eye drop.OthersThe safety and effectiveness of Besifloxacin in infants below one year of age have not been established...

Tk.350.00/=

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Betaderm N 10 gm Oint.

Betaderm N 10 gm Oint.

Betaderm N 10 gm Oint.IndicationsIndicated for the treatment of the following conditions where secondary bacterial infection is present, suspected, or likely to occur; eczema in adults and children (aged 2 years and over), including atopic and discoid eczemas; prurigo nodularis; psoriasis (excluding widespread plaque psoriasis); neurodermatoses including lichen simplex and lichen planus; seborrhoeic dermatitis; contact sensitivity reactions; insect bite reactions; and anal and genital intertrigo.Dosage & AdministrationApply sparingly to the affected area 2 to 3 times daily until an improvement occurs. In children, course should be limited to 5 daysSide EffectsBurning, itching, irritation, dryness, folliculitis, hypertrychosis, acneiform eruptions, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria may be reported.PrecautionsLong-term continuous topical therapy should be avoided where possible, particularly in infants and children. Infants and children up to four years should not be treated with topical steroids for longer than 3 weeks without medical review.Use in Pregnancy & LactationThere are no adequate and well controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids and should not be used extensively for a prolonged period.StorageProtect from light. Do not freeze. Store between 15 °C and 30 °C.Commercial PackBetaderm N Ointment: Each tube contains 10 gm ointment...

Tk.22.00/=

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Betaderm Oint.

Betaderm Oint.

Betaderm Oint.IndicationsIndicated in atopic, infantile & discoid eczema; prurigo nodularis; Psoriasis (excluding widespread plague psoriasis); lichen simplex or planus; contact sensitivity reactions; seborrhoeic dermatitis; discoid lupus erythematosus & adjunct to systemic steroid therapy in generalized erythroderma.Dosage & AdministrationApply sparingly to the affected area 2 to 3 times daily until an improvement occurs.Side EffectsBurning, itching, irritation, dryness, folliculitis, hypertrychosis acneiform eruptions, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliariamay be reported.PrecautionsAvoid long-term therapy particularly in infant & children; the treated area should not be bandaged or otherwise covered or wrapped as to be occlusive unless directed by the physician. Avoid contact with eyes.Use in Pregnancy & LactationThere are no adequate and well controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids and should not be used extensively for a prolonged period. Caution should be excercised when topical corticosteroids are administered in nursing women.StorageProtect from light. Do not freeze. Store between 15 °C and 30 °C.Commercial PackEach tube contains 15 gm ointment...

Tk.35.00/=

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Betamesal Scalp Lotion

Betamesal Scalp Lotion

Betamesal Scalp LotionIndicationsBetamesal Scalp Lotion is indicated for the relief of inflammatory manifestations of psoriasis and seborrhea of the scalp. Betamesal scalp Lotion is also indicated for the relief of inflammatory manifestations of non-scalp lesions of psoriasis and other corticosteroid responsive dermatoses.Dosage & AdministrationApply few drops of Betamesal Scalp Lotion to the affected area and massage gently and thoroughly onto the scalp or skin. The usual frequency of application is twice daily, in the morning and at night.Side EffectsSide effects that have been reported with the application of topical corticosteroids include burning, itching, irritation, dryness, folliculitis, hypertrichosis, hypopigmentation, perioral dermatitis, and allergic contact dermatitis. Salicylic Acid preparations may cause dermatitis.PrecautionsIf irritation or sensitization develops with the use of Betamesal Scalp Lotion, treatment should be discontinued. Systemic absorption of topical corticosteroids or Salicylic Acid may be increased if extensive body surface areas are treated. Application of Salicylic Acid to open wounds or damaged skin should be avoided.Use in Pregnancy & LactationThe safety of this medicine during pregnancy and breastfeeding has not been established. However, topical steroid should not be used extensively in pregnancy i.e. in large amount or for prolonged period.Over DoseOverdose of topical corticosteroids can suppress pituitary-adrenal functions resulting in secondary adrenal insufficiency and produce manifestations of hypercorticism, including Cushing's disease. With topical preparations containing Salicylic Acid, overdose of it may result in symptoms of salicyclism.Commercial PackEach bottle contains 30 ml lotion..

Tk.150.00/=

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Betastin Eye Drop

Betastin Eye Drop

Betastin Eye DropIndicationsBetastin is indicated for the treatment of itching associated with signs and symptoms of allergic conjunctivitis.Dosage & AdministrationInstill one drop of Betastin eye drops into the affected eye(s) twice a day.Pediatric Use: Safety and effectiveness in children below the age of 2 years have not been established.Side EffectsThe most common reported side effect occurring in approximately 25% of subjects was a mild taste following instillation. Other side effects occurring in 2-5% of subjects were eye irritation, headache, and nasopharyngitis.Precautions• To minimize the risk of contamination, do not touch dropper tip to any surface.• It should not be used to treat contact lens-related irritation.• Patients should be advised not to wear contact lens when using this drop.Use in Pregnancy & LactationPregnancy: Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. It should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus.Lactation: It is not known if Bepotastine besilate is excreted in human milk. Caution should be exercised when it is administered to a nursing woman.Drug InteractionNo information provided.Over DoseNo information provided.Storage• Store in a cool, dry place & protected from light• Keep out of reach of children• Do not use more than 4 weeks after opening.Commercial PackBetastin Sterile Eye Drops: Each plastic dropper bottle contains 5 ml of sterile eye drops...

Tk.300.00/=

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Beuflox 250

Beuflox 250

Beuflox 250IndicationsCiprofloxacin is indicated for the treatment of the following infections caused by sensitive bacteria:Severe systemic infections: e.g; septicemia, bacteremia, peritonitis, infections in immunosuppressed patients with haematological or solid tumors and in patients in intensive care unit with specific problems such as infected burns.Respiratory tract infections: Lobar and broncho pneumonia, acute and chronic bronchitis and empyema.Urinary tract infections: Uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis and epididymitis.Skin and soft tissue infections: Infected ulcers, wound infections, abscesses, cellulitis, otitis externa, erysipelas and infected burns.Gastrointestinal infections: Enteric fever, infective diarrhea.Infections of the biliary tract: Cholangitis, cholecystitis, empyema of the gall bladder.Intra-abdominal infections: Peritonitis, intra abdominal abscesses.Bone and joint infections: Osteomyelitis, septic arthritis.Pelvic infections: Salpingitis, endometritis, pelvic inflammatory diseases.Eye, ear, nose and throat infections: Otitis media, sinusitis, mastoiditis, tonsillitis.Gonorrhoea: Urethral, rectal and pharyngeal gonorrhoea caused by beta-lactamase producing organism or organisms moderately sensitive to penicillin.Dosage & AdministrationAdult Dose:For oral dosage &suspension:Urinary Tract infection: Acute uncomplicated: 250 mg twice daily for 3 days; Mild/Moderate: 250 mg twice daily for 7 to 14 days; Severe/Complicated: 500 mg twice daily for 7 to 14 days; Chronic Bacterial Prostitis : 500 mg twice daily for 28 days; Lower Respiratory Tract infection: Mild/Moderate: 500 mg twice daily for 7 to 14 days, Severe/Complicated : 750 mg twice daily for 7 to 14 days; Acute Sinusitis : 500 mg twice daily for 10 days; Skin and Skin Structure infection: Mild/Moderate : 500 mg twice daily for 7 to 14 days, Severe/Complicated : 750 mg twice daily for 7 to 14 days, Bone and joint infection: Mild/Moderate 500 mg twice daily for 4 to 6 weeks, Severe/Complicated : 750 mg twice daily for 4 to 6 weeks, Intra Abdominal Infection: 500 mg twice daily for 7 to 14 days, Infectious Diarrhea: Mild/Moderate/Severe: 500 mg twice daily for 5 to 7 days, Typhoid Fever : 500 mg twice daily for 10 days, Urethral & Cervical Gonococcal Infections: Uncomplicated: 250 mg Single dose.For IV infusion :Urinary Tract Infection: Mild to Moderate: 200 mg 12 hourly for 7-14 days;Severe or Complicated: 400 mg 12 hourly for 7-14 days; Lower Respiratory Tract infection: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days; Nosocomial Pneumonia: Mild/Moderate/Severe: 400 mg 8 hourly for 10-14 days; Skin and Skin Structure: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days; Bone and Joint Infection: Mild to Moderate: 400 mg 12 hourly for more than 4-6 weeks; Severe/Comlicated: 400 mg 8 hourly for more than 4-6weeks; Intra abdominal (Acute abdomen): Complicated: 400 mg 12 hourly for 7-14 days; Acute Sinusitis: Mild/Moderate: 400 mg 12 hourly for10 days: Chronic Bacterial Prostatitis: Mild/Moderate: 400 mg 12 hourly for 28 Days.Children and adolescents:RTI & GI infections: Neonate-15mg/kg twice daily, Child (1 month -18 years)-20mg/kg (max 750 mg) twice daily; UTI: Neonate-10 mg/kg twice daily, Child (1 month -18 years)-10mg/kg (max 750 mg) twice daily; Pseudomonal lower respiratory tract infection in cystic fibrosis: Child (1 month -18 years) - 20mg/kg (max 750 mg) twice daily; Anthrax (treatment & post exposure prophylaxis): Child (1 month -18 years) - 20mg/kg (max 750 mg) twice daily.Use in Pregnancy and LactationReproduction studies performed in rats and rabbits using parenteral and oral administration did not reveal any evidence of teratogenicity, impairment of fertility or impairment of pre or postnatal development. However, as with other quinolones, Ciprofloxacin has been shown to cause arthropathy in immature animals and therefore, its use during pregnancy is not recommended. Studies in rats have indicated that Ciprofloxacin is secreted in milk, administration to nursing mothers is thus not recommended.Side EffectsCiprofloxacin is generally well tolerated. Frequent adverse reactions are- Gastrointestinal disturbance: e.g. nausea diarrhea, vomiting, dyspepsia, abdominal pain. Disturbance of the CNS: e.g. dizziness, headache, tiredness, confusion, convulsions. Hypersensitivity reactions: e.g. skin rashes, pruritus, and possible systemic reactions. Other possible side effects are - joint pain, light sensitivity, transient increase in liver enzyme (especially in patients with history of liver damage), serum bilirubin, urea or serum creatinine. Arthralgia and myalgia may also occur.PrecautionsCiprofloxacin should be used with caution in patients with a history of convulsive disorders. Crystalluria related to the use of Ciprofloxacin has been observed only rarely. P..

Tk.8.50/=

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