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Omidon 15ml Pediatric Sus

Omidon 15ml Pediatric Sus

Omidon 15 ml SuspDescriptionOmidon is a Dopamine antagonist .Because it does not readily enter the central nervous system, its effects are confined to the periphery and acts principally at the receptor in the chemoreceptor trigger zone.Indications1. Stimulation of gut mobilitya) Non-ulcer dyspepsiab) Esophageal reflux, reflux esophagitis and gastritisc) Diabetic gastroparesisd) Functional dyspepsiae) Speeding barium transit in 'follow-through' radiological studies2. Prevention and symptomatic relief of acute nausea and vomiting from any causeincluding cytotoxic therapy, radio therapy and anti-parkinsonism therapy3. In the treatment of migraine.Dosage & AdministrationThe recommended oral dose forAdults : 10 - 20 mg every 4 - 8 hours dailyChildren : 0.2 - 0.4 mg/kg every 4 - 8 hours daily.Note : Omidon tablet and suspension should be taken 15 - 30 minutes before a meal.For acute nausea and vomiting, maximum period of treatment is 12 weeks.Side EffectsDomperidone may produce hyperprolactinemia(1.3% frequency). This may result in galactorrhea, breast enlargement and soreness and reduced libido. Dry mouth (1.9%), thirst, headache (1.2%), nervousness, drowsiness (0.4%), diarrhea (0.2%), skin rash and itching (0.1%) may occur during treatment with Domperidome. Extra-pyramidal reactions are seen in 0.05% of patients in clinical studies.PrecautionsDomperidone should be used with absolute caution in case of children because there may be an increased risk of extra-pyramidal reactions in young children because of an incompletely developed blood-brain barrier.Use in Pregnancy & LactationPregnant women : The safety of Domperidone has not been proven and it is therefore not recommended during pregnancy.Animal studies have not demonstrated teratogenic effects on the fetus.Lactating mother : Domperidone may precipitate galactorrhea and improve post-natal lactation. It is secreted in breast milk but in very small quantities insufficient to be considered harmful.Drug InteractionDomperidone may reduce the hypoprolactinemic effect of bromocriptine. The action of Domperidone on GI function may be antagonized by anti-muscarinics and opioid analgesics.Over DoseThere are no reported cases of overdosage...

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