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Tenil 3 mg Tab

Tenil 3 mg Tab

Tenil 3 mg TabDESCRIPTIONTenil (Bromazepam) is a pyridylben-zodiazepine compound with anxiolytic properties. Peak plasma concentrations are reached within two hours of oral administration of Tenil (Bromazepam). On average, 70% of Tenil (Bromazepam) is bound to plasma proteins. Tenil(Bromazepam) is metabolized in the liver. Quantitatively, two metabolites predominate: 3-hydroxybromazepam and 2-(2-amino-5-bromo-3-hydroxy-benzoyl) pyridine. Tenil(Bromazepam) has an elimination half-life of around 20 hours, but the half-life may be longer in elderly subjects.The metabolites are excreted in the urine mainly in conjugated form.COMPOSITIONEach tablet contains Bromazepam BP 3 mg.INDICATIONSEmotional disturbances such as anxiety and tension states, depressive mood, nervous tension, agitation and insomnia.Functional disturbances of the cardiovascular and the respiratory systems such as pseudoangina pectoris, tachycardia, emotiogenic hypertension and hyperventilation.Functional disturbances of the gastro-intestinal tract including irritable bowel syndrome, ulcerative colitis, epigastric pain, spasm.Functional disturbances of the genitourinary tract such as intense irritable bladder and dysmenorrhea.Other psychosomatic disturbances such as psychogenic headache, psychogenic dermatosis.Tenil (Bromazepam) is also suitable for treatment of anxiety and tension states originating in chronic organic disease and as an adjunct to psychotherapy in psychoneurosis.DOSAGE AND ADMINISTRATIONAdults : The optimum dosage and frequency of administration of Tenil (Bromazepam) should be based on the individual patient, the severity of symptoms and previous psychotropic drug history. The usual dosage in general practice is from 3 mg to 18 mg daily in divided doses. In exceptional circumstances, in hospitalised patients up to the maximum daily dosage of 60 mg, in divided doses, may be given. Elderly : Doses should not exceed half those normally recommended.Children : Tenil (Bromazepam) is gene-rally not indicated for children.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSCommon side effects include drow-siness, tiredness, reduced alertness, unsteadiness and ataxia; these are dose-related and may persist into the following day, even after a single dose. Other side-effects are rare and include headache, vertigo, hypotension, gastrointestinal upsets, skin rashes, visual disturbances, changes in libido and urinary retention.CONTRAINDICATIONSTenil (Bromazepam) is contraindicated in patients with known hypersensitivity to benzodiazepines. It is also contrain-dicated in severe respiratory failure, sleep apnea syndrome, myasthenia gravis and severe liver failure.PRECAUTIONSIn patients with chronic renal or hepatic disease, dosage may need to be reduced. Patients should be advised that,like all medicaments of this type, Tenil (Bromazepam) may modify patients' performance at skilled tasks (driving, operating machinery, etc.). Patients should further be advised that alcohol may intensify any impairment and should therefore be avoided during treatment. reduced. Patients should be advised that, like all medicaments of this type, Tenil (Bromazepam) may modify patients' performance at skilled tasks (driving, operating machinery, etc.). Patients should further be advised that alcohol may intensify any impairment and should therefore be avoided during treatment.Use in pregnancy and lactationTenil (Bromazepam) should not be used during pregnancy, especially during the first and last trimesters, unless there are compelling reasons.Benzodiazepines have been detected in breast milk. If possible, the use of Tenil (Bromazepam) should be avoided during lactation.DRUG INTERACTIONSWhen Tenil (Bromazepam) is combined with other centrally acting drugs such as antidepressant, hypnotic, narcotic analgesic, neuroleptic, antiepileptic, sedative antihistamine or anesthetic, its CNS sedative effect may be increased.SUPPLYEach box contains 10 x 10's tablets in blister strips...

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