Hypertension/High Blood Pressure

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Camoval 5/160 mg Tablet

Camoval 5/160 mg Tablet

Camoval 5/160 mg Tablet..

Tk.16.11/=

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Camoval 5/80 mg Tablet

Camoval 5/80 mg Tablet

Camoval 5/80 mg Tablet..

Tk.9.06/=

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Cardipin 10

Cardipin 10

Cardipin 10..

Tk.5.00/=

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Cardipin 5 mg tab

Cardipin 5 mg tab

Cardipin 5 mg tab..

Tk.5.00/=

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Cardipin PLUS 5/50

Cardipin PLUS 5/50

Cardipin PLUS 5/50..

Tk.6.00/=

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Cardopril 25

Cardopril 25

Cardopril 251. What is and what it is used for?Cardopril (Captopril) is the first of a new class of antihypertensive agents a highly specific inhibitor of angiotensin converting enzyme. It is also effective in the management of heart failure. Cardopril is designated chemically as (1-[(2S)-3 Mercapto-2 methyl propionyl-L-proline.) Cardopril is available in potencies of 25 mg & 50 mg as scored tablet for oral administration. Cardopril inhibits angiotenin converting enzyme (ACE) involved in the conversion of angiotensin I to angiotensin II and may also reduce the degradation of bradykinin. Cardopril produces a reduction in total peripheral resistance and in patients with congestive heart failure & reduction in both preload and post load. Following oral administration, Cardopril produces a maximal effect within 1 to 2 hours, although the full effect may not develop for several weeks during chronic dosing. The duration of action is dose dependent and may persist for 6 to 12 hours.Cardopril is used for mild to moderate hypertension as an adjunct to thiazide therapy in patients who have not responded effectively to thiazide treatment alone. Severe hypertension where standard therapy has failed. Cardopril is effective alone and in combination with other antihypertensive agents especially thiazide type diuretics. The blood pressure lowering effect of Cardopril and thiazides are approximately additive. It is also used as an adjunct to the treatment of severe congestive heart failure.2. Before you take Cardopril®Do not take this medicine and tell your doctor if:A history of previous hypersensitivity to Captopril is present. Do not take this medicine if the above applies to you. If you are not sure, talk to your doctor before taking Cardopril.Take special care with CardoprilCardopril should be used with great caution in patients with impaired renal function particularly if reno vascular disease is present or suspected and in patients with collagen vascular disorders such as systemic lupus erythematosus or scleroderma. Renal function should be assessed in all patients prior to administration of Cardopril. Patients with existing renal diseases or taking high doses of Captopril should be monitored regularly for proteinuria. Regular white blood cell counts should be made during the initial stage of therapy particularly in patients with collagen vascular disorders or impaired renal function and in patients receiving immunosuppressive therapy. Cardopril should not be used in patients with aortic stenosis or outflow tract obstruction. Patients with congestive heart failure and patients who are likely to be salt or water depleted due to concomitant treatment with diuretics or dialysis may experience symptomatic hypertension during the initial stages of Cardopril therapy, this may be minimized by starting with a low dose, preferably on retiring.Taking other medicinesDiuretics potentiate the antihypertensive effectiveness of Cardopril. Potassium scanning diuretics (triameterene, amiloride and spironolactone) or potassium supplements may cause significant increase in serum potassium. Cardopril has been reported to act synergistically with peripheral vasodilators such as minimal. Concomitant therapy with indomethacin and possibly other nonsteroidal anti-inflammatory drugs may reduce the antihypertensive effect of Cardopril. Caution should be exercised in prescribing Cardopril for patients receiving concomitant therapy with immunosuppressant, procainamide alopurinal and other drugs known to cause neutropenia especially in patients with impaired renal function.Pregnancy and breast-feedingThere are no adequate and well controlled studies in pregnant women. Cardopril should be used during pregnancy or for patient likely to become pregnant only if the potential benefit justifies a potential risk to the fetus. Cardopril is excreted in breast milk & should not be used in nursing mothers.3. How to take Cardopril®?Rapid absorption occurs after administration of therapeutic dose of Cardopril & peak blood level is achieved at about one hour. Presence of food in gastrointestinal tract reduces absorption by 30-40 percent. Cardopril therefore SHOULD BE GIVEN ONE HOUR BEFORE MEALS.Hypertension: Treatment with Cardopril should be at the lowest effective dose, which should be titrated according to the need of the patients.Mild to moderate hypertension: In mild to moderate hypertension, Captopril therapy should be used as an adjunct to thiazide therapy. Starting dose is 12.5 mg twice daily. The usual maintenance dose is 25 mg twice daily, which can be increased incrementally, at 2-4 weeks intervals, until a satisfactory response is achieved to a maximum of 50 mg twice daily.Severe hypertension: Starting dose is 12.5 mg twice daily and can be increased incrementally to a maximum of 50 mg thrice daily.Cardopril should be used together with other antihypertensive agent but the dose of those should be individually titrated.A daily dose ..

Tk.3.01/=

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CCB 5 Tab

CCB 5 Tab

CCB 5 Tab..

Tk.3.01/=

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Co-Diovan 160/25 Tab

Co-Diovan 160/25 Tab

Co-Diovan 160/25 Tab..

Tk.66.20/=

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Co-Diovan 80/12.5 Tab

Co-Diovan 80/12.5 Tab

Co-Diovan 80/12.5 Tab..

Tk.48.14/=

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Co-Disys 160/5 tab

Co-Disys 160/5 tab

Co-Disys 160/5 tab..

Tk.18.00/=

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Co-Disys 80/5 Tab

Co-Disys 80/5 Tab

Co-Disys 80/5 Tab..

Tk.10.00/=

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Co-Valtin 5/160 mg Tablet

Co-Valtin 5/160 mg Tablet

Co-Valtin 5/160 mg TabletCo-Valtin Tablet is manufactured by Acme Laboratories Limited. Co-Valtin Tablet contains 5 mg+160 mg Amlodipine + Valsartan. It is Combined antihypertensive preparations class drug.Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Amlodipine has a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure.Valsartan is an oral medication that belongs to a class of drugs called angiotensin receptor blockers (ARBs). It is orally active and specific angiotensin II antagonist acting on the AT1 subtype. Angiotensin's attachment to the receptors causes the blood vessels to narrow (vasoconstrict) which leads to an increase in blood pressure (hypertension). Valsartan blocks the angiotensin II receptor. By blocking the action of angiotensin, Valsartan dilates blood vessels and reduces blood pressure without affecting pulse rate. Valsartan has much greater affinity (about 20,000-fold) for the AT1 receptor than for the AT2 receptor. It does not bind or block other hormone receptors or ion channels known to be important in cardiovascular regulation.DosageCo-Valtin contains Amlodipine + Valsartan 5 mg+160 mg. Co-Valtin Dosage:Amlodipine is an effective treatment of hypertension in once daily doses of 2.5 mg to 10 mg while Valsartan is effective in doses of 80 mg to 320 mg. The majority of the antihypertensive effect is attained within 2 weeks after initiation of therapy or a change in dose. The dosage can be increased after 1 to 2 weeks of therapy to a maximum of one 10/320 mg tablet once daily as needed to control blood pressure.Co-Valtin may be administered with or without food. Co-Valtin may be administered with other antihypertensive agents. A patient whose blood pressure is not adequately controlled with Amlodipine alone or with Valsartan alone may be switched to their combination therapy.Elderly patients: Because of decreased clearance of Amlodipine, therapy should usually be initiated at 2.5 mg.Renal impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment. Titrate slowly in patients with severe renal impairment.Hepatic impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency. Titrate slowly in patients with hepatic impairment.Side EffectsThe most common side effects include peripheral edema, vertigo, nasopharyngitis, upper respiratory tract infection and dizziness.PrecautionCo-Valtin should be used with caution because there is a risk for- fetal or neonatal morbidity hypotension myocardial infarction or increased anginaDose should be titrated slowly in patients with impaired hepatic or severely impaired renal function. In general, calcium channel blockers should be used with caution in patients with heart failure.InteractionNo drug interaction studies have been conducted with Amlodipine and Valsartan combination and other drugs, although studies have been conducted with the individual Amlodipine and Valsartan componentsPregnancy Lactation usePregnancy: Amlodipine and Valsartan combination should not be used in 2nd and 3rd trimester because it can cause fetal death .Nursing Mothers: It is not known whether Valsartan and Amlodipine are excreted in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.ContraindicationAmlodipine and Valsartan combination is contraindicated in patients who are hypersensitive to any compounds of this product.Pediatric use: The safety and effectiveness has not been established in pediatric patients.Geriatric use: No differences in overall incidence of adverse events were observed in elderly...

Tk.16.04/=

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Co-Valtin 5/80 mg Tablet

Co-Valtin 5/80 mg Tablet

Co-Valtin 5/80 mg TabletCo-Valtin Tablet is manufactured by Acme Laboratories Limited. Co-Valtin Tablet contains 5 mg+160 mg Amlodipine + Valsartan. It is Combined antihypertensive preparations class drug.Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Amlodipine has a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure.Valsartan is an oral medication that belongs to a class of drugs called angiotensin receptor blockers (ARBs). It is orally active and specific angiotensin II antagonist acting on the AT1 subtype. Angiotensin's attachment to the receptors causes the blood vessels to narrow (vasoconstrict) which leads to an increase in blood pressure (hypertension). Valsartan blocks the angiotensin II receptor. By blocking the action of angiotensin, Valsartan dilates blood vessels and reduces blood pressure without affecting pulse rate. Valsartan has much greater affinity (about 20,000-fold) for the AT1 receptor than for the AT2 receptor. It does not bind or block other hormone receptors or ion channels known to be important in cardiovascular regulation.DosageCo-Valtin contains Amlodipine + Valsartan 5 mg+160 mg. Co-Valtin Dosage:Amlodipine is an effective treatment of hypertension in once daily doses of 2.5 mg to 10 mg while Valsartan is effective in doses of 80 mg to 320 mg. The majority of the antihypertensive effect is attained within 2 weeks after initiation of therapy or a change in dose. The dosage can be increased after 1 to 2 weeks of therapy to a maximum of one 10/320 mg tablet once daily as needed to control blood pressure.Co-Valtin may be administered with or without food. Co-Valtin may be administered with other antihypertensive agents. A patient whose blood pressure is not adequately controlled with Amlodipine alone or with Valsartan alone may be switched to their combination therapy.Elderly patients: Because of decreased clearance of Amlodipine, therapy should usually be initiated at 2.5 mg.Renal impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment. Titrate slowly in patients with severe renal impairment.Hepatic impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency. Titrate slowly in patients with hepatic impairment.Side EffectsThe most common side effects include peripheral edema, vertigo, nasopharyngitis, upper respiratory tract infection and dizziness.PrecautionCo-Valtin should be used with caution because there is a risk for- fetal or neonatal morbidity hypotension myocardial infarction or increased anginaDose should be titrated slowly in patients with impaired hepatic or severely impaired renal function. In general, calcium channel blockers should be used with caution in patients with heart failure.InteractionNo drug interaction studies have been conducted with Amlodipine and Valsartan combination and other drugs, although studies have been conducted with the individual Amlodipine and Valsartan componentsPregnancy Lactation usePregnancy: Amlodipine and Valsartan combination should not be used in 2nd and 3rd trimester because it can cause fetal death .Nursing Mothers: It is not known whether Valsartan and Amlodipine are excreted in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.ContraindicationAmlodipine and Valsartan combination is contraindicated in patients who are hypersensitive to any compounds of this product.Pediatric use: The safety and effectiveness has not been established in pediatric patients.Geriatric use: No differences in overall incidence of adverse events were observed in elderly...

Tk.9.00/=

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Combicard Tablet

Combicard Tablet

Combicard Tablet..

Tk.6.00/=

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Diovan 160 mg Tablet

Diovan 160 mg Tablet

Diovan 160 mg Tablet..

Tk.57.00/=

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Diovan 320 Tab

Diovan 320 Tab

Diovan 320 Tab..

Tk.70.20/=

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Diovan 40 Tab

Diovan 40 Tab

Diovan 40 Tab..

Tk.36.00/=

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DIOVAN 80 MG TAB FORIEN

DIOVAN 80 MG TAB FORIEN

DIOVAN 80 MG TAB FORIEN..

Tk.48.00/=

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Diovan 80 mg Tablet

Diovan 80 mg Tablet

Diovan 80 mg Tablet..

Tk.40.00/=

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Diplor 10

Diplor 10

Diplor 10..

Tk.7.00/=

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Diplor 5

Diplor 5

Diplor 5..

Tk.5.00/=

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Diplor PLUS 5/25

Diplor PLUS 5/25

Diplor PLUS 5/25..

Tk.3.50/=

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Diplor PLUS-50 Tab

Diplor PLUS-50 Tab

Diplor PLUS-50 Tab..

Tk.6.00/=

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Disys 160mg tablet

Disys 160mg tablet

Disys 160mg tablet..

Tk.18.00/=

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Disys 80mg Tablet

Disys 80mg Tablet

Disys 80mg Tablet..

Tk.10.00/=

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Duoblock 5/20 Tab

Duoblock 5/20 Tab

This product is a combination of two antihypertensive drugs: a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker), amlodipine besilate, and an angiotensin II receptor blocker, olmesartan medoxomil. The amlodipine component inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle, and the olmesartan medoxomil component blocks the vasoconstrictor effects of angiotensin II.Pharmacokinetics:Absorption: After oral administration of therapeutic doses of amlodipine, absorption produces peak plasma concentrations between 6 and 12 hours. Absolute bioavailability is estimated as between 64% and 90%. The absolute bioavailability of olmesartan medoxomil is approximately 26%. After oral administration, the peak plasma concentration (Cmax) of olmesartan is reached after 1 to 2 hours. Distribution: Approximately 93% of the circulating amlodipine is bound to plasma proteins in hypertensive patients. Steady-state plasma levels of amlodipine are reached after 7 to 8 days of consecutive daily dosing. The volume of distribution of olmesartan is approximately 17 L. Olmesartan is highly bound to plasma proteins (99%). Metabolism & Excretion: Amlodipine is extensively (about 90%) converted to inactive metabolites via hepatic metabolism. Its terminal elimination half-life is about 30 to 50 hours. 10% of the parent compound and 60% of the metabolites are excreted in the urine. Following the rapid and complete conversion of olmesartan medoxomil to olmesartan during absorption, there is virtually no further metabolism of olmesartan. Total plasma clearance of olmesartan is 1.3 L/h; with a renal clearance of 0.6 L/h. Approximately 35% to 50% of the absorbed dose is recovered in urine while the remainder is eliminated in feces via the bile. Its terminal elimination half-life is approximately 13 hours...

Tk.10.00/=

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Duoblock 5/40 Tab

Duoblock 5/40 Tab

This product is a combination of two antihypertensive drugs: a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker), amlodipine besilate, and an angiotensin II receptor blocker, olmesartan medoxomil. The amlodipine component inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle, and the olmesartan medoxomil component blocks the vasoconstrictor effects of angiotensin II.Pharmacokinetics:Absorption: After oral administration of therapeutic doses of amlodipine, absorption produces peak plasma concentrations between 6 and 12 hours. Absolute bioavailability is estimated as between 64% and 90%. The absolute bioavailability of olmesartan medoxomil is approximately 26%. After oral administration, the peak plasma concentration (Cmax) of olmesartan is reached after 1 to 2 hours. Distribution: Approximately 93% of the circulating amlodipine is bound to plasma proteins in hypertensive patients. Steady-state plasma levels of amlodipine are reached after 7 to 8 days of consecutive daily dosing. The volume of distribution of olmesartan is approximately 17 L. Olmesartan is highly bound to plasma proteins (99%). Metabolism & Excretion: Amlodipine is extensively (about 90%) converted to inactive metabolites via hepatic metabolism. Its terminal elimination half-life is about 30 to 50 hours. 10% of the parent compound and 60% of the metabolites are excreted in the urine. Following the rapid and complete conversion of olmesartan medoxomil to olmesartan during absorption, there is virtually no further metabolism of olmesartan. Total plasma clearance of olmesartan is 1.3 L/h; with a renal clearance of 0.6 L/h. Approximately 35% to 50% of the absorbed dose is recovered in urine while the remainder is eliminated in feces via the bile. Its terminal elimination half-life is approximately 13 hours...

Tk.17.00/=

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Duopres 5/20 Tab

Duopres 5/20 Tab

Duopres 5/20 Tab..

Tk.8.00/=

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Duopress 5/40 tab

Duopress 5/40 tab

Duopres 5/40 tab..

Tk.14.00/=

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Duovas 5/20

Duovas 5/20

Duovas 5/20..

Tk.12.00/=

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Emlon 5 Tab

Emlon 5 Tab

Emlon 5 Tab..

Tk.5.00/=

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Emlon PLUS tab

Emlon PLUS tab

Emlon PLUS tab..

Tk.6.00/=

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EXFORGE 5 mg/160mg Tab

EXFORGE 5 mg/160mg Tab

EXFORGE 5 mg/160mg Tab..

Tk.70.75/=

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EXFORGE 5 mg/80mg Tab

EXFORGE 5 mg/80mg Tab

EXFORGE 5 mg/80mg Tab..

Tk.50.50/=

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EXFORGE10 mg/160mg Tab

EXFORGE10 mg/160mg Tab

EXFORGE10 mg/160mg Tab..

Tk.79.09/=

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Fixocard 25 Tab

Fixocard 25 Tab

Fixocard 25 TabDescriptionFixocard is a fixed-dose combination of Amlodipine and Atenolol. Amlodipine is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle; it has a greater effect on vascular smooth muscle than on cardiac muscle. Amlodipine is a peripheral vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure. Amlodipine reduces tone, decreases coronary vasoreactivity and lowers cardiac demand by reducing after load. Atenolol is a cardio selective beta-blocker. The cardio-selectivity is dose-related. Atenolol causes a reduction in blood pressure by lowering cardiac output, decreasing the plasma renin activity and sympathetic outflow from CNS. Atenolol also causes a reduction in myocardial oxygen demand by virtue of its negative inotropic and negative chronotropic effects.IndicationsPatients with essential hypertension; Patients with angina pectoris & hypertension as co-existing diseases; In post MI patients; In patients with refractory angina pectoris where nitrate therapy has failed.Dosage & AdministrationThe recommended dosage is Fixocard or Fixocard 25 one tablet daily. If necessary, the dosage may be increased to two tablets daily or as advised by the physicians. The dosage however should be individualized.Side EffectsThe combination of Amlodipine and Atenolol is well tolerated. Overall side-effects include fatigue, headache, edema, nausea drowsiness, anxiety and depression.PrecautionsBronchospasm: The combination should be used with caution in patients with airway obstruction.Renal impairment: The combination can be used in patients with renal impairment. However, caution may be necessary if the creatinine clearance is less than 30 ml/min because of possible reduction in the excretion of unchanged Atenolol.Hepatic impairment: Caution may be necessary in the use of the combination in patients with severe liver damage because of prolongation of the elimination half-life of Amlodipine.Drug withdrawal: Since coronary heart disease may exist without being recognized, patients should be warned against stopping the drug suddenly. Any discontinuation should be gradual and under observation.Use in Pregnancy & LactationPregnancy: The combination should be used during pregnancy only if the expected benefit outweighs the potential fetal risk.Nursing Mother: The combination should not be used by nursing mothers. If its use is considered necessary, breast-feeding should be stopped.Drug InteractionDisopyramide: Atenolol reduces the clearance of disopyramide by 20%. Additive negative inotropic effects on the heart may be produced. Ampicillin: at doses of 1 gm and above may reduce Atenolol levels. Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion e.g. in response to oral antidiabetics. Atenolol has less potential for these actions.Over DoseThough not documented, hypotension and less frequently congestive cardiac failure may occur in cases of overdosage. Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal. Symptomatic treatment is suggested.Commercial PackFixocard 25 tablet: Each box contains 5 blister strips of 10 tablets...

Tk.5.25/=

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Fixocard 50 Tab

Fixocard 50 Tab

Fixocard 50 TabDescriptionFixocard is a fixed-dose combination of Amlodipine and Atenolol. Amlodipine is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle; it has a greater effect on vascular smooth muscle than on cardiac muscle. Amlodipine is a peripheral vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure. Amlodipine reduces tone, decreases coronary vasoreactivity and lowers cardiac demand by reducing after load. Atenolol is a cardio selective beta-blocker. The cardio-selectivity is dose-related. Atenolol causes a reduction in blood pressure by lowering cardiac output, decreasing the plasma renin activity and sympathetic outflow from CNS. Atenolol also causes a reduction in myocardial oxygen demand by virtue of its negative inotropic and negative chronotropic effects.IndicationsPatients with essential hypertension; Patients with angina pectoris & hypertension as co-existing diseases; In post MI patients; In patients with refractory angina pectoris where nitrate therapy has failed.Dosage & AdministrationThe recommended dosage is Fixocard or Fixocard 25 one tablet daily. If necessary, the dosage may be increased to two tablets daily or as advised by the physicians. The dosage however should be individualized.Side EffectsThe combination of Amlodipine and Atenolol is well tolerated. Overall side-effects include fatigue, headache, edema, nausea drowsiness, anxiety and depression.PrecautionsBronchospasm: The combination should be used with caution in patients with airway obstruction.Renal impairment: The combination can be used in patients with renal impairment. However, caution may be necessary if the creatinine clearance is less than 30 ml/min because of possible reduction in the excretion of unchanged Atenolol.Hepatic impairment: Caution may be necessary in the use of the combination in patients with severe liver damage because of prolongation of the elimination half-life of Amlodipine.Drug withdrawal: Since coronary heart disease may exist without being recognized, patients should be warned against stopping the drug suddenly. Any discontinuation should be gradual and under observation.Use in Pregnancy & LactationPregnancy: The combination should be used during pregnancy only if the expected benefit outweighs the potential fetal risk.Nursing Mother: The combination should not be used by nursing mothers. If its use is considered necessary, breast-feeding should be stopped.Drug InteractionDisopyramide: Atenolol reduces the clearance of disopyramide by 20%. Additive negative inotropic effects on the heart may be produced. Ampicillin: at doses of 1 gm and above may reduce Atenolol levels. Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion e.g. in response to oral antidiabetics. Atenolol has less potential for these actions.Over DoseThough not documented, hypotension and less frequently congestive cardiac failure may occur in cases of overdosage. Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal. Symptomatic treatment is suggested.Commercial PackFixocard 50 tablet: Each box contains 5 blister strips of 10 tablets...

Tk.8.00/=

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Fusid 20mg injection

Fusid 20mg injection

Indication: Cardiac, pulmonary, hepatic and renal oedema, peripheral oedema and hypertension.Dosage & Administration:Tablet : In mild cases, 20 mg daily or 40 mg on alternate days. In resistant cases, 80 mg/day. Children- 1 to 3 mg/kg/day, max. 40 mg/day. Injection : 20-50 mg/day IM/IV. Children- 0.5-1.5 mg/kg/day. max. 20 mg/day...

Tk.8.00/=

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Larb 50 mg tab

Larb 50 mg tab

Larb 50 mg tab..

Tk.8.03/=

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Lodicard 5/50mg Tab

Lodicard 5/50mg Tab

Lodicard 5/50mg Tab..

Tk.6.00/=

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Lodipin-5mg Tab

Lodipin-5mg Tab

Lodipin-5mg Tab..

Tk.5.00/=

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lovapres-5mg-tablet, 1 strip

Lovapres 5mg Tablet, 1 Strip

Lovapres 5mg Tablet, 1 StripDescription:Lovapres(Amlodipine) is a long-acting calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Thus it causes reduction in peripheral vascular resistance and contractile process in cardiac muscle and reduces blood pressure.IndicationLovapres(Amlodipine) is a calcium channel blocker and may be used alone or in combination with other antihypertensive and antianginal agents for the treatment of Hypertension and Coronary Artery Disease (such as Chronic Stable Angina, Vasospastic Angina and Angiographically Documented Coronary Artery Disease in patients without heart failure or an ejection fraction < 40%) .Dosage & AdministrationAdult: Starting dose 5 mg once daily with maximum dose 10 mg once daily. Small, Fragile and Elderly patients or patients with hepatic insufficiency: Starting dose 2.5 mg once daily.Pediatric: Starting dose 2.5 mg to 5 mg once daily.ContraindicationIt is contraindicated in patients with known sensitivity to AmlodipinePrecautionSymptomatic hypotension is possible, particularly in patients with severe aortic stenosis. However, because of the gradual onset of action, acute hypotension is unlikely. Worsening angina and acute myocardial infarction can develop after starting or increasing the dose of Amlodipine, particularly in patients with severe obstructive coronary artery disease. Titrate slowly when administering calcium channel blockers to patients with severe hepatic impairment.Side EffectsMost common side effects are headache and edema which occurred in a dose related manner. Other side effects not dose related but reported with an incidence >1.0% are headache, fatigue, nausea, abdominal pain and somnolence.Drug InteractionAmlodipine has been safely administered with thiazide diuretics, alpha blockers, beta blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerine, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs. Amlodipine has no effect on protein binding of digoxin, phenytoin, warfarin, or indomethacin. Administration of Amlodipine with grapefruit or grapefruit juice is not recommended as bioavailability may be increased in some patients resulting in increased blood pressure lowering effects.Pregnancy & LactationPregnancy Category C. There are no adequate and well-controlled studies of Amlodipine in pregnant women. Amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Amlodipine is excreted in human milk. In the absence of this information, it is recommended that nursing be discontinued while Amlodipine is administered.Storage Conditionkeep in a dry place away from light and heat. Keep out of the reach of children...

Tk.50.00/=

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Nopidin 5

Nopidin 5

Nopidin 5..

Tk.3.00/=

  0 отзывов

Olmepres Plus Tab

Olmepres Plus Tab

Olmepres Plus Tab..

Tk.8.00/=

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Olmezest AM 20 Tab

Olmezest AM 20 Tab

Olmezest AM Tab..

Tk.8.52/=

  0 отзывов

Orbapin 5/20 mg Tablet

Orbapin 5/20 mg Tablet

Orbapin 5/20 mg TabletDescriptionORBAPIN is a combination of two antihypertensive drugs containing Amlodipine, a dihydropyridine calcium channel blocker and Olmesartan Medoxomil, an angiotensin II receptor antagonist. Amlodipine inhibits the transmembrane influx of calcium ions into vascular smooth & cardiac muscle. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascularresistance and a reduction in blood pressure. Olmesartan is an angiotensin II receptor antagonist that acts on AT1 subtype by blocking the action of angiotensin II receptor. Olmesartan dilates blood vessels and reduces blood pressure without affecting pulse rate.CompositionORBAPIN 5/20: Each film-coated tablet contains Amlodipine Besilate BP equivalent to Amlodipine 5 mg and Olmesartan Medoxomil BP 20 mg.ORBAPIN 5/40: Each film-coated tablet contains Amlodipine Besilate BP equivalent to Amlodipine 5 mg and Olmesartan Medoxomil BP 40 mg.IndicationORBAPIN is indicated for the treatment of hypertension, alone orwith other antihypertensive agents. ORBAPIN may also be used as initial therapy in patients who are likely to need multiple antihypertensive agents to achieve their blood pressure goals.Dosage & AdministrationInitial therapyThe usual starting dose of ORBAPIN is one tablet (5/20 mg) once daily. The starting dosage can be increased after 1 to 2 weeks of therapy to a maximum dose of two tablets of ORBAPIN (5/20 mg) once daily as needed to control blood pressure.ORBAPIN 5/40 may be administered in patients whose blood pressure is not adequately controlled by ORBAPIN 5/20.Maximum antihypertensive effects are attained within 2 weeks after a change in dose. ORBAPIN may be taken with or without food. ORBAPIN may be administered with other antihypertensive agents. Initial therapy with this combination is not recommended in patient’s ≥75 years old or with hepatic impairment. No initial dose adjustment is recommended for patients with moderate to marked renal impairment (Creatinine clearance < 40 mL/min).Combination of Amlodipine and Olmesartan is not recommended below Creatinine clearance < 20 mL/min.Replacement therapyORBAPIN may be substituted for its individual titrated components. When substituting for individual components, the dose of one or both of the components can be increased if blood pressure control has not been satisfactory.Add-on therapyORBAPIN may be used to provide additional blood pressure lowering for patients not adequately control with Amlodipine (or another dihydropyridine calcium channel blocker) alone or withOlmesartan Medoxomil (or another angiotensin II receptor blocker) alone.OR, AS DIRECTED BY PHYSICIAN.Side EffectsThe reported side effects were generally mild and seldom led to discontinuation of treatment. The most common side effects include peripherial edema, flushing, palpitations, dizziness. Other side effects that occurred in placebo-controlled clinical trials are orthostatic hypotension, diarrhea, rash, abdominal pain, fatigue, back pain, pruritus, rhabdomyolysis.ContraindicationHypersensitivity to any of the component of this combination product.Precautions07 1353 / 01Hypotension in Volume or Salt-Depleted patients: Symptomatic hypotension may occur initiation of treatment. Vasodilation: Cautions should be exercised when administering the drug, particularly in patients with severe aortic stenosis.Patients with Severe Obstructive Coronary Artery Disease: Patients may develop increased frequency, duration, or severity of angina or acute myocardial infarction on starting calcium channel blocker therapy or at the time of dosage increase. Patients with Congestive Heart Failure: Calcium channel blockers should be used with caution in patients with heart failure. Patient with impaired Renal Function: Caution should be exercised when administering the drug to patients with renal impairment. Patients with Hepatic Impairment: Caution should be exercised when administering the drug to patients with severe hepatic impairment.Use in pregnancy & LactationPregnancy: When pregnancy is detected, discontinue this combination product as soon as possible. When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus.Lactation: Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug.Paediatric UseThe safety and effectiveness of Amlodipine & Olmesartan combination in paediatric patients have not been established.Drug InteractionsIn clinical trials, Amlodipine has been safely administered with thiazide diuretic, beta blockers, angiotensin converting enzyme inhibitors, long acting nitrates, sublingual nitroglycerin, digoxin, warfarin, NSAID’s, antibiotic and oral hypoglycemic drugs. No significant drug interactions were reported in ..

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Osartil 100 mg Tablet

Osartil 100 mg Tablet

Osartil 100 mg TabletDescriptionOsartil (Losartan Potassium), the first of a new class of antihypertensives, is an angiotensin II receptor (type AT1) antagonist. Angiotensin II is a potent vasoconstrictor, the primary vasoactive hormone of the renin-angiotensin system and an important component in the pathophysiology of hypertension. Losartan and its principal active metabolite block the vasoconstriction and aldosterone secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor found in many tissues. Osartil is now regarded as the first-line therapy option for treating high blood pressure.IndicationsLosartan is indicated for the treatment of all grades of hypertension, Chronic heart failure, Stroke risk reduction in hypertension & LVH and Nephropathy in type 2 Diabetes. It may be used alone or in combination with other antihypertensive agents. It is an effective alternative for patients who have to discontinue an ACE inhibitor because of persistent dry cough.Dosage & AdministrationHypertension: The usual starting dose is 50 mg once daily. In patients with possible depletion of intravascular volume or patients with a history of hepatic impairment, starting dose is 25 mg once daily. Losartan can be administered once or twice daily with total daily doses ranging from 25 mg to 100 mg. No initial dosage adjustment is necessary for elderly or renal impairment patients. If blood pressure is not controlled by Losartan, a low dose of a diuretic (Hydrochlorothiazide) may be added. Losartan may be administered with or without food. Chronic heart failure: 12.5 mg once daily, increased at weekly intervals to 50 mg once daily if tolerated, Stroke risk reduction in hypertension & LVH: 50 mg once daily. Hydrochlorothiazide 12.5 mg daily should added. Maximum dose-Losartan 100 mg followed by Hydrochlorothiazide 25 mg once daily. Nephropathy in type 2 Diabetes: 50 mg once daily. Maximum dose-100 mg once daily.Side EffectsOverall incidence of adverse effects of Osartil is comparable to placebo in clinical studies. The most common adverse events occuring with Osartil at a rate of >1% above placebo were upper respiratory infection (7.9% vs 6.9%), dizziness (3.5% vs 2.1%) and leg pain (1.0% vs 0.0%).PrecautionsOsartil should be used with caution in patients with known hypersensitivity to the drugs that act through renin-angiotensin system. Special precaution should be taken when it is administered to the patients with renal and hepatic impairment. Safety and effectivenss of Osartil in pediatric patients have not been established.Use in Pregnancy & LactationOsartil must be discontinued as soon as possible when pregnancy is detected. It should not be prescribed during lactation as there is no information in humans on the passage of Losartan (Osartil) into breast milk.Drug InteractionNo drug interactions of clinical significance have been identified. Drugs which have been studied in clinical pharmacokinetic trials include - (1) Hydrochlorothiazide,(2) Digoxin, (3) Warfarin, (4) Cimetidine, (5) Ketoconazole and (6) Phenobarbital.StorageStore in a dry place, at between 15 °C and 30 °C, away from light...

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Osartil 25 mg Tab

Osartil 25 mg Tab

Osartil 25 TabDescriptionOsartil (Losartan Potassium), the first of a new class of antihypertensives, is an angiotensin II receptor (type AT1) antagonist. Angiotensin II is a potent vasoconstrictor, the primary vasoactive hormone of the renin-angiotensin system and an important component in the pathophysiology of hypertension. Losartan and its principal active metabolite block the vasoconstriction and aldosterone secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor found in many tissues. Osartil is now regarded as the first-line therapy option for treating high blood pressure.IndicationsLosartan is indicated for the treatment of all grades of hypertension, Chronic heart failure, Stroke risk reduction in hypertension & LVH and Nephropathy in type 2 Diabetes. It may be used alone or in combination with other antihypertensive agents. It is an effective alternative for patients who have to discontinue an ACE inhibitor because of persistent dry cough.Dosage & AdministrationHypertension: The usual starting dose is 50 mg once daily. In patients with possible depletion of intravascular volume or patients with a history of hepatic impairment, starting dose is 25 mg once daily. Losartan can be administered once or twice daily with total daily doses ranging from 25 mg to 100 mg. No initial dosage adjustment is necessary for elderly or renal impairment patients. If blood pressure is not controlled by Losartan, a low dose of a diuretic (Hydrochlorothiazide) may be added. Losartan may be administered with or without food. Chronic heart failure: 12.5 mg once daily, increased at weekly intervals to 50 mg once daily if tolerated, Stroke risk reduction in hypertension & LVH: 50 mg once daily. Hydrochlorothiazide 12.5 mg daily should added. Maximum dose-Losartan 100 mg followed by Hydrochlorothiazide 25 mg once daily. Nephropathy in type 2 Diabetes: 50 mg once daily. Maximum dose-100 mg once daily.Side EffectsOverall incidence of adverse effects of Osartil is comparable to placebo in clinical studies. The most common adverse events occuring with Osartil at a rate of >1% above placebo were upper respiratory infection (7.9% vs 6.9%), dizziness (3.5% vs 2.1%) and leg pain (1.0% vs 0.0%).PrecautionsOsartil should be used with caution in patients with known hypersensitivity to the drugs that act through renin-angiotensin system. Special precaution should be taken when it is administered to the patients with renal and hepatic impairment. Safety and effectivenss of Osartil in pediatric patients have not been established.Use in Pregnancy & LactationOsartil must be discontinued as soon as possible when pregnancy is detected. It should not be prescribed during lactation as there is no information in humans on the passage of Losartan (Osartil) into breast milk.Drug InteractionNo drug interactions of clinical significance have been identified. Drugs which have been studied in clinical pharmacokinetic trials include - (1) Hydrochlorothiazide,(2) Digoxin, (3) Warfarin, (4) Cimetidine, (5) Ketoconazole and (6) Phenobarbital.StorageStore in a dry place, at between 15 °C and 30 °C, away from light...

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Osartil 50 mg Tab

Osartil 50 mg Tab

Osartil 50 TabDescriptionOsartil (Losartan Potassium), the first of a new class of antihypertensives, is an angiotensin II receptor (type AT1) antagonist. Angiotensin II is a potent vasoconstrictor, the primary vasoactive hormone of the renin-angiotensin system and an important component in the pathophysiology of hypertension. Losartan and its principal active metabolite block the vasoconstriction and aldosterone secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor found in many tissues. Osartil is now regarded as the first-line therapy option for treating high blood pressure.IndicationsLosartan is indicated for the treatment of all grades of hypertension, Chronic heart failure, Stroke risk reduction in hypertension & LVH and Nephropathy in type 2 Diabetes. It may be used alone or in combination with other antihypertensive agents. It is an effective alternative for patients who have to discontinue an ACE inhibitor because of persistent dry cough.Dosage & AdministrationHypertension: The usual starting dose is 50 mg once daily. In patients with possible depletion of intravascular volume or patients with a history of hepatic impairment, starting dose is 25 mg once daily. Losartan can be administered once or twice daily with total daily doses ranging from 25 mg to 100 mg. No initial dosage adjustment is necessary for elderly or renal impairment patients. If blood pressure is not controlled by Losartan, a low dose of a diuretic (Hydrochlorothiazide) may be added. Losartan may be administered with or without food. Chronic heart failure: 12.5 mg once daily, increased at weekly intervals to 50 mg once daily if tolerated, Stroke risk reduction in hypertension & LVH: 50 mg once daily. Hydrochlorothiazide 12.5 mg daily should added. Maximum dose-Losartan 100 mg followed by Hydrochlorothiazide 25 mg once daily. Nephropathy in type 2 Diabetes: 50 mg once daily. Maximum dose-100 mg once daily.Side EffectsOverall incidence of adverse effects of Osartil is comparable to placebo in clinical studies. The most common adverse events occuring with Osartil at a rate of >1% above placebo were upper respiratory infection (7.9% vs 6.9%), dizziness (3.5% vs 2.1%) and leg pain (1.0% vs 0.0%).PrecautionsOsartil should be used with caution in patients with known hypersensitivity to the drugs that act through renin-angiotensin system. Special precaution should be taken when it is administered to the patients with renal and hepatic impairment. Safety and effectivenss of Osartil in pediatric patients have not been established.Use in Pregnancy & LactationOsartil must be discontinued as soon as possible when pregnancy is detected. It should not be prescribed during lactation as there is no information in humans on the passage of Losartan (Osartil) into breast milk.Drug InteractionNo drug interactions of clinical significance have been identified. Drugs which have been studied in clinical pharmacokinetic trials include - (1) Hydrochlorothiazide,(2) Digoxin, (3) Warfarin, (4) Cimetidine, (5) Ketoconazole and (6) Phenobarbital.StorageStore in a dry place, at between 15 °C and 30 °C, away from light...

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Prosan 50 tablet

Prosan 50 tablet

Prosan 50 tablet1. What Prosan® is and what it is used for?Prosan® (Losartan Potassium) is an angiotensin-II receptor (type AT1) antagonist. Angiotensin-II is a potent vasoconstrictor, the primary vasoactive hormone of the renin-angiotensin system and an important component in the pathophysiology of hypertension. Losartan and its principal active metabolite block the vasoconstrictor and aldosterone secreting effects of angiotensin-II by selectively blocking the binding of angiotensin-II to the AT1 receptor found in many tissues. It is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.2. Before you take Prosan®ContraindicationLosartan Potassium is contraindicated in patients who are hypersensitive to the active ingredient or any component of the drug.OverdosageLimited data are available regarding overdosage in human. The most likely manifestation of overdosage would be hypotension and tachycardia; bradycardia could occur from parasympathetic (vagal) stimulation. Supportive treatment should include repletion of the intravascular volume.3. How to take Prosan®?The usual starting dose is 50 mg once daily, with 25 mg used in patients with possible depletion of intravascular volume (e.g., patients treated with diuretics) and patients with a history of hepatic impairment. It can be administered once or twice daily with total daily doses ranging from 25 mg to 100 mg.4. Possible side effectsIn clinical trials, dizziness was the only side effect reported that occurred with an incidence greater than placebo in 1% patients treated with Losartan. Rarely, rash was reported, although the incidence in controlled clinical trials was less than placebo. Angioedema, involving swelling of the face, lips and/or tongue, has been reported rarely in patients treated with Losartan. The incidence of cough is similar to placebo and significantly lower than that observed with ACE inhibitors.Use in Special PopulationChildren: There are no data on the safety or efficacy of Prosan® in children.Pregnant women: Prosan must be discontinued as soon as possible when pregnancy is detected. It should not be prescribed during lactation, as there is no information in human on the passage ofLosartan into breast milk.Elderly: In elderly patients up to 75 years of age, no dosage adjustment is necessary.5. How to store Prosan®?Store in a dry place, at temperature between 15° C and 30 0C, away from light. Prosan Prescribing Information..

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