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Pivalo 2mg Tablet
Indication: Pitavastatin is indicated as an adjunctive therapy to diet to reduce elevated total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG) and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia.Dosage & Administration:The dose range for Pitavastatin is 1 to 4 mg orally once daily at any time of the day with or without food. The recommended starting dose is 2 mg and the maximum dose is 4 mg. The starting dose and maintenance doses of Pitavastatin should be individualized according to patient characteristics, such as goal of therapy and response...
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Pivalo 4mg Tablet
Indication: Pitavastatin is indicated as an adjunctive therapy to diet to reduce elevated total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG) and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia.Dosage & Administration:The dose range for Pitavastatin is 1 to 4 mg orally once daily at any time of the day with or without food. The recommended starting dose is 2 mg and the maximum dose is 4 mg. The starting dose and maintenance doses of Pitavastatin should be individualized according to patient characteristics, such as goal of therapy and response...
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Rocovas 10 mg Tab
Rocovas 10 TabDescriptionRosuvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol.IndicationsRosuvastatin is indicated for- primary hypercholesterolaemia (type IIa including heterozygous familial hypercholesterolaemia), mixed dyslipidaemia (type IIb), or homozygousfamilial hypercholesterolaemia in patients who have not responded adequately to diet and other appropriate measures.Dosage & AdministrationDose range: 5-40 mg once daily. Initially 5-10 mg once daily increased if necessary at intervals of at least 4 weeks to 20 mg once daily. Daily dose can be increased after further 4 weeks to 40 mg only in severe hypercholesterolaemia with high cardiovascular risk and under specialist supervision. Elderly initially 5 mg once daily.HoFH: Starting dose 20 mg.In pediatric patients 10 to 17 years of age with HeFH, the usual dose range is 5-20 mg/day; doses greater than 20 mg have not been studied in this patient population.Use 40 mg dose only for patients not reaching LDL-C goal with 20 mgRosuvastatin can be taken with or without food, at any time of day.Side EffectsRosuvastatin is generally well tolerated. The adverse events seen with Rosuvastatin are generally mild and transient. Most commonly occurring side-effects are headache, myalgia, asthenia, constipation, dizziness, nausea, abdominal pain. Uncommonly pruritus, rash and urticaria may occur. Myopathy (including myositis), hypersensitivity reactions (including angioedema), rhabdomyolysis, pancreatitis etc are the rarely occurring side-effects of Rosuvastatin.PrecautionsSkeletal muscle effects (e.g., myopathy and rhabdomyolysis): Risks increase with use of 40 mg dose, advanced age (>65 year), hypothyroidism, renal impairment, and combination use with cyclosporine, lopinavir/ritonavir, atazanavir/ritonavir, or certain other lipid-lowering drugs. Patients should be advised to promptly report unexplained muscle pain, tenderness, or weakness. Rosuvastatin can be discontinued if signs or symptoms appear.Liver enzyme abnormalities and monitoring: Persistent elevations in hepatic transaminases can occur. Liver enzymes should be monitored before and during treatment.Use in Pregnancy & LactationRosuvastatin should be administered to women of childbearing age only when such patients are highly unlikely to conceive and have been informed of the potential hazards. If the patient becomes pregnant while taking this drug, therapy should be discontinued and the patient apprised of the potential hazard to the fetus. Because of the potential for adverse reactions in nursing infants, women taking Rosuvastatin should not breast-feed.Drug InteractionRemarkable drug interactions of Rosuvastatin are-Cyclosporine: Combination increases Rosuvastatin exposure. Rosuvastatin dose should be limited to 5 mg once daily.Gemfibrosil: Combination should be avoided. If used together, Rosuvastatin dose should be limited to 10 mg once daily.Lopinavir/Ritonavir or atazanavir/ritonavir: Combination increases Rosuvastatin exposure. Rosuvastatin dose should be to 10 mg once daily.Coumarin anticoagulants: Combination prolongs international normalized ratio (INR). Stable INR should be achieved prior to starting Rosuvastatin. INR should be monitored frequently until stable upon initiation or alteration of Rosuvastatin therapy.Concomitant lipid-lowering therapies: Use with fibrates and niacin products may increase the risk of skeletal muscle effects.Use in special populationAge and sex: There was no clinically relevant effect of age or sex on the pharmacokinetics of Rosuvastatin in adults.Race: Pharmacokinetic studies show an increase in exposure in Asian subjects compared with Caucasians.Pregnancy and lactation: The safety of rosuvastatin during pregnancy and whilst breast feeding has not been established.Severe renal impairment (not on hemodialysis): Starting dose is 5 mg, not to exceed 10 mgOver DoseThere is no specific treatment in the event of overdose. In the event of overdose, the patient should be treated symptomatically and supportive measures instituted as required. Haemodialysis is unlikely to be of benefit...
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Rocovas 20 mg Tab
Rocovas 20 tabDescriptionRosuvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol.IndicationsRosuvastatin is indicated for- primary hypercholesterolaemia (type IIa including heterozygous familial hypercholesterolaemia), mixed dyslipidaemia (type IIb), or homozygousfamilial hypercholesterolaemia in patients who have not responded adequately to diet and other appropriate measures.Dosage & AdministrationDose range: 5-40 mg once daily. Initially 5-10 mg once daily increased if necessary at intervals of at least 4 weeks to 20 mg once daily. Daily dose can be increased after further 4 weeks to 40 mg only in severe hypercholesterolaemia with high cardiovascular risk and under specialist supervision. Elderly initially 5 mg once daily.HoFH: Starting dose 20 mg.In pediatric patients 10 to 17 years of age with HeFH, the usual dose range is 5-20 mg/day; doses greater than 20 mg have not been studied in this patient population.Use 40 mg dose only for patients not reaching LDL-C goal with 20 mgRosuvastatin can be taken with or without food, at any time of day.Side EffectsRosuvastatin is generally well tolerated. The adverse events seen with Rosuvastatin are generally mild and transient. Most commonly occurring side-effects are headache, myalgia, asthenia, constipation, dizziness, nausea, abdominal pain. Uncommonly pruritus, rash and urticaria may occur. Myopathy (including myositis), hypersensitivity reactions (including angioedema), rhabdomyolysis, pancreatitis etc are the rarely occurring side-effects of Rosuvastatin.PrecautionsSkeletal muscle effects (e.g., myopathy and rhabdomyolysis): Risks increase with use of 40 mg dose, advanced age (>65 year), hypothyroidism, renal impairment, and combination use with cyclosporine, lopinavir/ritonavir, atazanavir/ritonavir, or certain other lipid-lowering drugs. Patients should be advised to promptly report unexplained muscle pain, tenderness, or weakness. Rosuvastatin can be discontinued if signs or symptoms appear.Liver enzyme abnormalities and monitoring: Persistent elevations in hepatic transaminases can occur. Liver enzymes should be monitored before and during treatment.Use in Pregnancy & LactationRosuvastatin should be administered to women of childbearing age only when such patients are highly unlikely to conceive and have been informed of the potential hazards. If the patient becomes pregnant while taking this drug, therapy should be discontinued and the patient apprised of the potential hazard to the fetus. Because of the potential for adverse reactions in nursing infants, women taking Rosuvastatin should not breast-feed.Drug InteractionRemarkable drug interactions of Rosuvastatin are-Cyclosporine: Combination increases Rosuvastatin exposure. Rosuvastatin dose should be limited to 5 mg once daily.Gemfibrosil: Combination should be avoided. If used together, Rosuvastatin dose should be limited to 10 mg once daily.Lopinavir/Ritonavir or atazanavir/ritonavir: Combination increases Rosuvastatin exposure. Rosuvastatin dose should be to 10 mg once daily.Coumarin anticoagulants: Combination prolongs international normalized ratio (INR). Stable INR should be achieved prior to starting Rosuvastatin. INR should be monitored frequently until stable upon initiation or alteration of Rosuvastatin therapy.Concomitant lipid-lowering therapies: Use with fibrates and niacin products may increase the risk of skeletal muscle effects.Use in special populationAge and sex: There was no clinically relevant effect of age or sex on the pharmacokinetics of Rosuvastatin in adults.Race: Pharmacokinetic studies show an increase in exposure in Asian subjects compared with Caucasians.Pregnancy and lactation: The safety of rosuvastatin during pregnancy and whilst breast feeding has not been established.Severe renal impairment (not on hemodialysis): Starting dose is 5 mg, not to exceed 10 mgOver DoseThere is no specific treatment in the event of overdose. In the event of overdose, the patient should be treated symptomatically and supportive measures instituted as required. Haemodialysis is unlikely to be of benefit...
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Rocovas 5 mg Tab
Rocovas 5 TabDescriptionRosuvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol.IndicationsRosuvastatin is indicated for- primary hypercholesterolaemia (type IIa including heterozygous familial hypercholesterolaemia), mixed dyslipidaemia (type IIb), or homozygousfamilial hypercholesterolaemia in patients who have not responded adequately to diet and other appropriate measures.Dosage & AdministrationDose range: 5-40 mg once daily. Initially 5-10 mg once daily increased if necessary at intervals of at least 4 weeks to 20 mg once daily. Daily dose can be increased after further 4 weeks to 40 mg only in severe hypercholesterolaemia with high cardiovascular risk and under specialist supervision. Elderly initially 5 mg once daily.HoFH: Starting dose 20 mg.In pediatric patients 10 to 17 years of age with HeFH, the usual dose range is 5-20 mg/day; doses greater than 20 mg have not been studied in this patient population.Use 40 mg dose only for patients not reaching LDL-C goal with 20 mgRosuvastatin can be taken with or without food, at any time of day.Side EffectsRosuvastatin is generally well tolerated. The adverse events seen with Rosuvastatin are generally mild and transient. Most commonly occurring side-effects are headache, myalgia, asthenia, constipation, dizziness, nausea, abdominal pain. Uncommonly pruritus, rash and urticaria may occur. Myopathy (including myositis), hypersensitivity reactions (including angioedema), rhabdomyolysis, pancreatitis etc are the rarely occurring side-effects of Rosuvastatin.PrecautionsSkeletal muscle effects (e.g., myopathy and rhabdomyolysis): Risks increase with use of 40 mg dose, advanced age (>65 year), hypothyroidism, renal impairment, and combination use with cyclosporine, lopinavir/ritonavir, atazanavir/ritonavir, or certain other lipid-lowering drugs. Patients should be advised to promptly report unexplained muscle pain, tenderness, or weakness. Rosuvastatin can be discontinued if signs or symptoms appear.Liver enzyme abnormalities and monitoring: Persistent elevations in hepatic transaminases can occur. Liver enzymes should be monitored before and during treatment.Use in Pregnancy & LactationRosuvastatin should be administered to women of childbearing age only when such patients are highly unlikely to conceive and have been informed of the potential hazards. If the patient becomes pregnant while taking this drug, therapy should be discontinued and the patient apprised of the potential hazard to the fetus. Because of the potential for adverse reactions in nursing infants, women taking Rosuvastatin should not breast-feed.Drug InteractionRemarkable drug interactions of Rosuvastatin are-Cyclosporine: Combination increases Rosuvastatin exposure. Rosuvastatin dose should be limited to 5 mg once daily.Gemfibrosil: Combination should be avoided. If used together, Rosuvastatin dose should be limited to 10 mg once daily.Lopinavir/Ritonavir or atazanavir/ritonavir: Combination increases Rosuvastatin exposure. Rosuvastatin dose should be to 10 mg once daily.Coumarin anticoagulants: Combination prolongs international normalized ratio (INR). Stable INR should be achieved prior to starting Rosuvastatin. INR should be monitored frequently until stable upon initiation or alteration of Rosuvastatin therapy.Concomitant lipid-lowering therapies: Use with fibrates and niacin products may increase the risk of skeletal muscle effects.Use in special populationAge and sex: There was no clinically relevant effect of age or sex on the pharmacokinetics of Rosuvastatin in adults.Race: Pharmacokinetic studies show an increase in exposure in Asian subjects compared with Caucasians.Pregnancy and lactation: The safety of rosuvastatin during pregnancy and whilst breast feeding has not been established.Severe renal impairment (not on hemodialysis): Starting dose is 5 mg, not to exceed 10 mgOver DoseThere is no specific treatment in the event of overdose. In the event of overdose, the patient should be treated symptomatically and supportive measures instituted as required. Haemodialysis is unlikely to be of benefit...
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Rostab 10 mg Tablet
Rostab 10 mg TabletCOMPOSITIONROSTAB 5 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 5 mg.ROSTAB 10 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 10 mg.ROSTAB 20 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 20 mg.INDICATION AND USEHeterozygous Hypercholesterolemia (Familial and Nonfamilial)Homozygous Hypercholesterolemia (Familial)Mixed Dyslipidemia (Fredrickson Type IIa and IIb)DOSAGE AND ADMINISTRATIONHeterozygous Hypercholesterolemia (Familial and Nonfamilial) andMixed Dyslipidemia (Fredrickson Type IIa and IIb)The usual recommended starting dose of Rosuvastatin is 10 mg once daily. Initiation of therapy with 5 mg once daily may be considered for patients requiring less aggressive LDL-C reductions or who havepredisposing factor for myopathy. For patients with marked hypercholesterolemia (LDL-C 190 mg/dl) and aggressive lipid target a 20 mg starting dose may be considered .The 40 mg dose ofRosuvastatin should be reserved for those patients who have not achieved goal LDL-C at 20 mg.Homozygous Hypercholesterolemia (Familial)The recommended starting dose of Rosuvastatin is 20 mg once daily in patients with homozygous FH. The maximum recommended dose of Rosuvastatin is 40 mg.Rosuvastatin should be used in these patients as an adjunct to other lipid lowering treatments (eg. LDL apheresis) or if such treatments are unavailable. Patients with renal insufficiency No modification of dosage is necessary for patients with mild to moderate renal insufficiency.For patients with severe renal impairment (CLcr 30 ml/min/1.73 m2) the dosing of Rosuvastatin should be started at 5 mg once daily and not to exceed 10 mg once daily.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSRosuvastatin is generally well tolerated. The most frequent adverse events thought to be related to Rosuvastatin were myalgia, constipation, asthenia, abdominal pain, and nausea.CONTRAINDICATIONSRosuvastatin is contraindicated in patients with a known hypersensitivity to any component of this product. Rosuvastatin is contraindicated in patients with active liver disease or with unexplained persistent elevation of serum transaminase. Caution should be taken in patients with hypocalcemia and risk-benefit should be considered.USE IN PREGNANCY AND LACTATIONRosuvastatin should be administered to women of childbearing age only when such patients are highly unlikely to conceive. If the patient becomes pregnant while taking this drug, therapy should be discontinued immediately. It is not known whether Rosuvastatin is excreted in human milk.USE IN PEDIATRIC PATIENTSThe safety and effectiveness in pediatric patients have not been established.SUPPLYROSTAB 5 : Each box contains 3 x 10 tablets in Alu-Alu blister strip.ROSTAB 10 : Each box contains 2 x 10 tablets in Alu-Alu blister strip.ROSTAB 20 : Each box contains 1 x 10 tablets in Alu-Alu blister strip...
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Rostab 20 mg Tablet
Rostab 20 mg TabletCOMPOSITIONROSTAB 5 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 5 mg.ROSTAB 10 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 10 mg.ROSTAB 20 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 20 mg.INDICATION AND USEHeterozygous Hypercholesterolemia (Familial and Nonfamilial)Homozygous Hypercholesterolemia (Familial)Mixed Dyslipidemia (Fredrickson Type IIa and IIb)DOSAGE AND ADMINISTRATIONHeterozygous Hypercholesterolemia (Familial and Nonfamilial) andMixed Dyslipidemia (Fredrickson Type IIa and IIb)The usual recommended starting dose of Rosuvastatin is 10 mg once daily. Initiation of therapy with 5 mg once daily may be considered for patients requiring less aggressive LDL-C reductions or who havepredisposing factor for myopathy. For patients with marked hypercholesterolemia (LDL-C 190 mg/dl) and aggressive lipid target a 20 mg starting dose may be considered .The 40 mg dose ofRosuvastatin should be reserved for those patients who have not achieved goal LDL-C at 20 mg.Homozygous Hypercholesterolemia (Familial)The recommended starting dose of Rosuvastatin is 20 mg once daily in patients with homozygous FH. The maximum recommended dose of Rosuvastatin is 40 mg.Rosuvastatin should be used in these patients as an adjunct to other lipid lowering treatments (eg. LDL apheresis) or if such treatments are unavailable. Patients with renal insufficiency No modification of dosage is necessary for patients with mild to moderate renal insufficiency.For patients with severe renal impairment (CLcr 30 ml/min/1.73 m2) the dosing of Rosuvastatin should be started at 5 mg once daily and not to exceed 10 mg once daily.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSRosuvastatin is generally well tolerated. The most frequent adverse events thought to be related to Rosuvastatin were myalgia, constipation, asthenia, abdominal pain, and nausea.CONTRAINDICATIONSRosuvastatin is contraindicated in patients with a known hypersensitivity to any component of this product. Rosuvastatin is contraindicated in patients with active liver disease or with unexplained persistent elevation of serum transaminase. Caution should be taken in patients with hypocalcemia and risk-benefit should be considered.USE IN PREGNANCY AND LACTATIONRosuvastatin should be administered to women of childbearing age only when such patients are highly unlikely to conceive. If the patient becomes pregnant while taking this drug, therapy should be discontinued immediately. It is not known whether Rosuvastatin is excreted in human milk.USE IN PEDIATRIC PATIENTSThe safety and effectiveness in pediatric patients have not been established.SUPPLYROSTAB 5 : Each box contains 3 x 10 tablets in Alu-Alu blister strip.ROSTAB 10 : Each box contains 2 x 10 tablets in Alu-Alu blister strip.ROSTAB 20 : Each box contains 1 x 10 tablets in Alu-Alu blister strip...
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Rostab 5 mg Tab
Rostab 5 mg TabCOMPOSITIONROSTAB 5 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 5 mg.ROSTAB 10 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 10 mg.ROSTAB 20 : Each film-coated tablet contains Rosuvastatin Calcium INN equivalent to Rosuvastatin 20 mg.INDICATION AND USEHeterozygous Hypercholesterolemia (Familial and Nonfamilial)Homozygous Hypercholesterolemia (Familial)Mixed Dyslipidemia (Fredrickson Type IIa and IIb)DOSAGE AND ADMINISTRATIONHeterozygous Hypercholesterolemia (Familial and Nonfamilial) andMixed Dyslipidemia (Fredrickson Type IIa and IIb)The usual recommended starting dose of Rosuvastatin is 10 mg once daily. Initiation of therapy with 5 mg once daily may be considered for patients requiring less aggressive LDL-C reductions or who havepredisposing factor for myopathy. For patients with marked hypercholesterolemia (LDL-C 190 mg/dl) and aggressive lipid target a 20 mg starting dose may be considered .The 40 mg dose ofRosuvastatin should be reserved for those patients who have not achieved goal LDL-C at 20 mg.Homozygous Hypercholesterolemia (Familial)The recommended starting dose of Rosuvastatin is 20 mg once daily in patients with homozygous FH. The maximum recommended dose of Rosuvastatin is 40 mg.Rosuvastatin should be used in these patients as an adjunct to other lipid lowering treatments (eg. LDL apheresis) or if such treatments are unavailable. Patients with renal insufficiency No modification of dosage is necessary for patients with mild to moderate renal insufficiency.For patients with severe renal impairment (CLcr 30 ml/min/1.73 m2) the dosing of Rosuvastatin should be started at 5 mg once daily and not to exceed 10 mg once daily.OR AS DIRECTED BY THE PHYSICIAN.SIDE EFFECTSRosuvastatin is generally well tolerated. The most frequent adverse events thought to be related to Rosuvastatin were myalgia, constipation, asthenia, abdominal pain, and nausea.CONTRAINDICATIONSRosuvastatin is contraindicated in patients with a known hypersensitivity to any component of this product. Rosuvastatin is contraindicated in patients with active liver disease or with unexplained persistent elevation of serum transaminase. Caution should be taken in patients with hypocalcemia and risk-benefit should be considered.USE IN PREGNANCY AND LACTATIONRosuvastatin should be administered to women of childbearing age only when such patients are highly unlikely to conceive. If the patient becomes pregnant while taking this drug, therapy should be discontinued immediately. It is not known whether Rosuvastatin is excreted in human milk.USE IN PEDIATRIC PATIENTSThe safety and effectiveness in pediatric patients have not been established.SUPPLYROSTAB 5 : Each box contains 3 x 10 tablets in Alu-Alu blister strip.ROSTAB 10 : Each box contains 2 x 10 tablets in Alu-Alu blister strip.ROSTAB 20 : Each box contains 1 x 10 tablets in Alu-Alu blister strip...
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Rosu 10 mg Tablet
Rosu 10IndicationRosuvastatin is indicated for: Patients with primary hyperlipidemia and mixed dyslipidemia as an adjunct to diet to reduce elevated total-C, LDL-C, ApoB, non HDL-C and TG levels and to increase HDL-C.Patients with hypertriglyceredemia as an adjunct to diet.Patients with primary dysbetalipoproteinemia (Type III hyperlipoproteinemia) as an adjunct to diet.Patients with homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C, total-C, and ApoB.Slowing the progression of atherosclerosis as part of a treatment strategy to lower total-C and LDL-C as an adjunct to diet.Pediatric patients 10 to 17 years of age with heterozygous familial hypercholesterolemia (HeFH) to reduce elevated total-C, LDL-C and ApoB after failing an adequate trial of diet therapy.Risk reduction of Myocardial Infarction (MI), stroke and arterial revascularization procedures in patients without clinically evident CHD, but with multiple risk factors.Dosage & AdministrationGeneral Dosing Information:The dose range for Rosuvastatin is 5 to 40 mg orally once daily. The usual starting dose is 10-20 mg. Rosuvastatin can be administered as a single dose at any time of day, with or without food. When initiating Rosuvastatin therapy or switching from another HMG-CoA reductase inhibitor therapy, the appropriate Rosuvastatin starting dose should first be utilized, and only then titrated according to the patient`s response and individualized goal of therapy. After initiation or upon titration of Rosuvastatin, lipid levels should be analyzed within 2 to 4 weeks and the dosage adjusted accordingly. The 40 mg dose of Rosuvastatin should be used only for those patients who have not achieved their LDL-C goal utilizing the 20 mg dose.Heterozygous Familial Hypercholesterolemia in PediatricPatients (10 to 17 years of age): The usual dose range of Rosuvastatin is 5- 20 mg/day; the maximum recommended dose is 20 mg/day (doses greater than 20 mg have not been studied in this patient population). Doses should be individualized according to the recommended goal of therapy. Adjustments should be made atintervals of 4 weeks or more.PrecautionsRosuvastatin should be prescribed with caution in patients with predisposing factors for myopathy (e.g., age >65 years, inadequately treated hypothyroidism, renal impairment). The risk of myopathy during treatment with Rosuvastatin may be increased with concurrent administration of some other lipid-lowering therapies (Fibrates or Niacin), Gemfibrozil, Cyclosporine, Lopinavir/Ritonavir, or Atazanavir/Ritonavir. Rosuvastatin therapy should be discontinued if markedly elevated creatinine kinase levels occur or myopathy is diagnosed or suspected. Rosuvastatin therapy should also be temporarily withheld in any patient with an acute, serious condition suggestive of myopathy or predisposing to the development of renal failure secondary to rhabdomyolysis (e.g., sepsis, hypotension, dehydration, major surgery, trauma, severe metabolic, endocrine, and electrolyte disorders, or uncontrolled seizures). It is recommended that liver enzyme tests be performed before and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter...
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Rosu 20 mg Tablet
Rosu 20IndicationRosuvastatin is indicated for: Patients with primary hyperlipidemia and mixed dyslipidemia as an adjunct to diet to reduce elevated total-C, LDL-C, ApoB, non HDL-C and TG levels and to increase HDL-C.Patients with hypertriglyceredemia as an adjunct to diet.Patients with primary dysbetalipoproteinemia (Type III hyperlipoproteinemia) as an adjunct to diet.Patients with homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C, total-C, and ApoB.Slowing the progression of atherosclerosis as part of a treatment strategy to lower total-C and LDL-C as an adjunct to diet.Pediatric patients 10 to 17 years of age with heterozygous familial hypercholesterolemia (HeFH) to reduce elevated total-C, LDL-C and ApoB after failing an adequate trial of diet therapy.Risk reduction of Myocardial Infarction (MI), stroke and arterial revascularization procedures in patients without clinically evident CHD, but with multiple risk factors.Dosage & AdministrationGeneral Dosing Information:The dose range for Rosuvastatin is 5 to 40 mg orally once daily. The usual starting dose is 10-20 mg. Rosuvastatin can be administered as a single dose at any time of day, with or without food. When initiating Rosuvastatin therapy or switching from another HMG-CoA reductase inhibitor therapy, the appropriate Rosuvastatin starting dose should first be utilized, and only then titrated according to the patient`s response and individualized goal of therapy. After initiation or upon titration of Rosuvastatin, lipid levels should be analyzed within 2 to 4 weeks and the dosage adjusted accordingly. The 40 mg dose of Rosuvastatin should be used only for those patients who have not achieved their LDL-C goal utilizing the 20 mg dose.Heterozygous Familial Hypercholesterolemia in PediatricPatients (10 to 17 years of age): The usual dose range of Rosuvastatin is 5- 20 mg/day; the maximum recommended dose is 20 mg/day (doses greater than 20 mg have not been studied in this patient population). Doses should be individualized according to the recommended goal of therapy. Adjustments should be made atintervals of 4 weeks or more.PrecautionsRosuvastatin should be prescribed with caution in patients with predisposing factors for myopathy (e.g., age >65 years, inadequately treated hypothyroidism, renal impairment). The risk of myopathy during treatment with Rosuvastatin may be increased with concurrent administration of some other lipid-lowering therapies (Fibrates or Niacin), Gemfibrozil, Cyclosporine, Lopinavir/Ritonavir, or Atazanavir/Ritonavir. Rosuvastatin therapy should be discontinued if markedly elevated creatinine kinase levels occur or myopathy is diagnosed or suspected. Rosuvastatin therapy should also be temporarily withheld in any patient with an acute, serious condition suggestive of myopathy or predisposing to the development of renal failure secondary to rhabdomyolysis (e.g., sepsis, hypotension, dehydration, major surgery, trauma, severe metabolic, endocrine, and electrolyte disorders, or uncontrolled seizures). It is recommended that liver enzyme tests be performed before and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter...
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Rosu 5 mg Tablet
Rosu 5 mg TabletIndicationRosuvastatin is indicated for: Patients with primary hyperlipidemia and mixed dyslipidemia as an adjunct to diet to reduce elevated total-C, LDL-C, ApoB, non HDL-C and TG levels and to increase HDL-C.Patients with hypertriglyceredemia as an adjunct to diet.Patients with primary dysbetalipoproteinemia (Type III hyperlipoproteinemia) as an adjunct to diet.Patients with homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C, total-C, and ApoB.Slowing the progression of atherosclerosis as part of a treatment strategy to lower total-C and LDL-C as an adjunct to diet.Pediatric patients 10 to 17 years of age with heterozygous familial hypercholesterolemia (HeFH) to reduce elevated total-C, LDL-C and ApoB after failing an adequate trial of diet therapy.Risk reduction of Myocardial Infarction (MI), stroke and arterial revascularization procedures in patients without clinically evident CHD, but with multiple risk factors.Dosage & AdministrationGeneral Dosing Information:The dose range for Rosuvastatin is 5 to 40 mg orally once daily. The usual starting dose is 10-20 mg. Rosuvastatin can be administered as a single dose at any time of day, with or without food. When initiating Rosuvastatin therapy or switching from another HMG-CoA reductase inhibitor therapy, the appropriate Rosuvastatin starting dose should first be utilized, and only then titrated according to the patient`s response and individualized goal of therapy. After initiation or upon titration of Rosuvastatin, lipid levels should be analyzed within 2 to 4 weeks and the dosage adjusted accordingly. The 40 mg dose of Rosuvastatin should be used only for those patients who have not achieved their LDL-C goal utilizing the 20 mg dose.Heterozygous Familial Hypercholesterolemia in PediatricPatients (10 to 17 years of age): The usual dose range of Rosuvastatin is 5- 20 mg/day; the maximum recommended dose is 20 mg/day (doses greater than 20 mg have not been studied in this patient population). Doses should be individualized according to the recommended goal of therapy. Adjustments should be made atintervals of 4 weeks or more.PrecautionsRosuvastatin should be prescribed with caution in patients with predisposing factors for myopathy (e.g., age >65 years, inadequately treated hypothyroidism, renal impairment). The risk of myopathy during treatment with Rosuvastatin may be increased with concurrent administration of some other lipid-lowering therapies (Fibrates or Niacin), Gemfibrozil, Cyclosporine, Lopinavir/Ritonavir, or Atazanavir/Ritonavir. Rosuvastatin therapy should be discontinued if markedly elevated creatinine kinase levels occur or myopathy is diagnosed or suspected. Rosuvastatin therapy should also be temporarily withheld in any patient with an acute, serious condition suggestive of myopathy or predisposing to the development of renal failure secondary to rhabdomyolysis (e.g., sepsis, hypotension, dehydration, major surgery, trauma, severe metabolic, endocrine, and electrolyte disorders, or uncontrolled seizures). It is recommended that liver enzyme tests be performed before and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter...
Available for request
Rosutin 10 tablet
rosutin-10mgWhat Rosutin® is and what it is used for?Rosutin® belongs to a group of medicines called statins.You have been prescribed Rosutin® because:You have a high cholesterol level. This means you are at risk from a heart attack or stroke. Rosutin® is used in adults, adolescents and children 6 years or older to treat high cholesterol. You have been advised to take a statin, because changing your diet and taking more exercise were not enough to correct your cholesterol levels. You should continue with your cholesterol-lowering diet and exercise while you are taking Rosutin®. OrYou have other factors that increase your risk of having a heart attack, stroke or related health problems.Heart attack, stroke and other problems can be caused by a disease called atherosclerosis. Atherosclerosis is due to build-up of fatty deposits in your arteries.Why is it important to keep taking Rosutin®?Rosutin® is used to correct the levels of fatty substances in the blood called lipids, the most common of which is cholesterol.There are different types of cholesterol found in the blood – ‘bad’ cholesterol (LDL-C) and ‘good’ cholesterol (HDL-C).Rosutin® can reduce the ‘bad’ cholesterol and increase the ‘good’ cholesterol.It works by helping to block your body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood.For most people, high cholesterol does not affect the way they feel because it does not produce any symptoms. However, if it is left untreated, fatty deposits can build up in the walls of your blood vessels causing them to narrow.Sometimes, these narrowed blood vessels can get blocked which can cut off the blood supply to the heart or brain leading to a heart attack or a stroke. By lowering your cholesterol levels, you can reduce your risk of having a heart attack, a stroke or related health problems.You need to keep taking Rosutin®, even if it has got your cholesterol to the right level, because it prevents your cholesterol levels from creeping up again and causing build up of fatty deposits. However, you should stop if your doctor tells you to do so, or you have become pregnant.What you need to know before you take Rosutin®Do not take Rosutin®:If you have ever had an allergic reaction to Rosutin®, or to any of its ingredients.If you are pregnant or breast-feeding. If you become pregnant while taking Rosutin® stop taking it immediately and tell your doctor. Women should avoid becoming pregnant while taking Rosutin® by using suitable contraception.If you have liver disease.If you have severe kidney problems.If you have repeated or unexplained muscle aches or pains.If you take a drug called ciclosporin (used, for example, after organ transplants)If any of the above applies to you (or you are in doubt), please go back and see your doctor.Warnings and precautionsTalk to your doctor or pharmacist before taking Rosutin®.If you have problems with your kidneys.If you have problems with your liver.If you have had repeated or unexplained muscle aches or pains, a personal or family history of muscle problems, or a previous history of muscle problems when taking other cholesterol-lowering medicines. Tell your doctor immediately if you have unexplained muscle aches or pains especially if you feel unwell or have a fever. Also tell your doctor or pharmacist if you have a muscle weakness that is constant.If you regularly drink large amounts of alcohol.If your thyroid gland is not working properly.If you take other medicines called fibrates to lower your cholesterol. Please read this leaflet carefully, even if you have taken other medicines for high cholesterol before.If you take medicines used to treat the HIV infection e.g. ritonavir with lopinavir and/or atazanavir.If you take antibiotics containing fusidic acid, please see Other medicines and Rosutin®.Children and adolescentsIf the patient is under 6 years old: Rosutin® should not be given to children younger than 6 years.If the patient is below 18 years of age: The Rosuvastatin 40 mg tablet is not suitable for use in children and adolescents below 18 years of age.If you are over 70 (as your doctor needs to choose the right start dose of Rosutin® to suit you)If you have severe respiratory failure.If you are of Asian origin - that is Japanese, Chinese, Filipino, Vietnamese, Korean and Indian. Your doctor needs to choose the right start dose of Rosutin® to suit you.If any of the above applies to you (or if you are not sure):Do not take Rosuvastatin 40 mg (the highest dose) and check with your doctor or pharmacist before you actually start taking any dose of Rosutin®.In a small number of people, statins can affect the liver. This is identified by a simple test which looks for increased levels of liver enzymes in the blood. For this reason, your doctor will usually carry out this blood test (liver function test) before and during treatment with Rosutin®.While you..
Available for request
Rosutin 20 mg Tab
Rosutin 20 mg TabWhat Rosutin® is and what it is used for?Rosutin® belongs to a group of medicines called statins.You have been prescribed Rosutin® because:You have a high cholesterol level. This means you are at risk from a heart attack or stroke. Rosutin® is used in adults, adolescents and children 6 years or older to treat high cholesterol. You have been advised to take a statin, because changing your diet and taking more exercise were not enough to correct your cholesterol levels. You should continue with your cholesterol-lowering diet and exercise while you are taking Rosutin®. OrYou have other factors that increase your risk of having a heart attack, stroke or related health problems.Heart attack, stroke and other problems can be caused by a disease called atherosclerosis. Atherosclerosis is due to build-up of fatty deposits in your arteries.Why is it important to keep taking Rosutin®?Rosutin® is used to correct the levels of fatty substances in the blood called lipids, the most common of which is cholesterol.There are different types of cholesterol found in the blood – ‘bad’ cholesterol (LDL-C) and ‘good’ cholesterol (HDL-C).Rosutin® can reduce the ‘bad’ cholesterol and increase the ‘good’ cholesterol.It works by helping to block your body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood.For most people, high cholesterol does not affect the way they feel because it does not produce any symptoms. However, if it is left untreated, fatty deposits can build up in the walls of your blood vessels causing them to narrow.Sometimes, these narrowed blood vessels can get blocked which can cut off the blood supply to the heart or brain leading to a heart attack or a stroke. By lowering your cholesterol levels, you can reduce your risk of having a heart attack, a stroke or related health problems.You need to keep taking Rosutin®, even if it has got your cholesterol to the right level, because it prevents your cholesterol levels from creeping up again and causing build up of fatty deposits. However, you should stop if your doctor tells you to do so, or you have become pregnant.What you need to know before you take Rosutin®Do not take Rosutin®:If you have ever had an allergic reaction to Rosutin®, or to any of its ingredients.If you are pregnant or breast-feeding. If you become pregnant while taking Rosutin® stop taking it immediately and tell your doctor. Women should avoid becoming pregnant while taking Rosutin® by using suitable contraception.If you have liver disease.If you have severe kidney problems.If you have repeated or unexplained muscle aches or pains.If you take a drug called ciclosporin (used, for example, after organ transplants)If any of the above applies to you (or you are in doubt), please go back and see your doctor.Warnings and precautionsTalk to your doctor or pharmacist before taking Rosutin®.If you have problems with your kidneys.If you have problems with your liver.If you have had repeated or unexplained muscle aches or pains, a personal or family history of muscle problems, or a previous history of muscle problems when taking other cholesterol-lowering medicines. Tell your doctor immediately if you have unexplained muscle aches or pains especially if you feel unwell or have a fever. Also tell your doctor or pharmacist if you have a muscle weakness that is constant.If you regularly drink large amounts of alcohol.If your thyroid gland is not working properly.If you take other medicines called fibrates to lower your cholesterol. Please read this leaflet carefully, even if you have taken other medicines for high cholesterol before.If you take medicines used to treat the HIV infection e.g. ritonavir with lopinavir and/or atazanavir.If you take antibiotics containing fusidic acid, please see Other medicines and Rosutin®.Children and adolescentsIf the patient is under 6 years old: Rosutin® should not be given to children younger than 6 years.If the patient is below 18 years of age: The Rosuvastatin 40 mg tablet is not suitable for use in children and adolescents below 18 years of age.If you are over 70 (as your doctor needs to choose the right start dose of Rosutin® to suit you)If you have severe respiratory failure.If you are of Asian origin - that is Japanese, Chinese, Filipino, Vietnamese, Korean and Indian. Your doctor needs to choose the right start dose of Rosutin® to suit you.If any of the above applies to you (or if you are not sure):Do not take Rosuvastatin 40 mg (the highest dose) and check with your doctor or pharmacist before you actually start taking any dose of Rosutin®.In a small number of people, statins can affect the liver. This is identified by a simple test which looks for increased levels of liver enzymes in the blood. For this reason, your doctor will usually carry out this blood test (liver function test) before and during treatment with Rosutin®.Whil..
Available for request
Rosutin 5 Tablet
Rosutin 5 TabletWhat Rosutin® is and what it is used for?Rosutin® belongs to a group of medicines called statins.You have been prescribed Rosutin® because:You have a high cholesterol level. This means you are at risk from a heart attack or stroke. Rosutin® is used in adults, adolescents and children 6 years or older to treat high cholesterol. You have been advised to take a statin, because changing your diet and taking more exercise were not enough to correct your cholesterol levels. You should continue with your cholesterol-lowering diet and exercise while you are taking Rosutin®. OrYou have other factors that increase your risk of having a heart attack, stroke or related health problems.Heart attack, stroke and other problems can be caused by a disease called atherosclerosis. Atherosclerosis is due to build-up of fatty deposits in your arteries.Why is it important to keep taking Rosutin®?Rosutin® is used to correct the levels of fatty substances in the blood called lipids, the most common of which is cholesterol.There are different types of cholesterol found in the blood – ‘bad’ cholesterol (LDL-C) and ‘good’ cholesterol (HDL-C).Rosutin® can reduce the ‘bad’ cholesterol and increase the ‘good’ cholesterol.It works by helping to block your body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood.For most people, high cholesterol does not affect the way they feel because it does not produce any symptoms. However, if it is left untreated, fatty deposits can build up in the walls of your blood vessels causing them to narrow.Sometimes, these narrowed blood vessels can get blocked which can cut off the blood supply to the heart or brain leading to a heart attack or a stroke. By lowering your cholesterol levels, you can reduce your risk of having a heart attack, a stroke or related health problems.You need to keep taking Rosutin®, even if it has got your cholesterol to the right level, because it prevents your cholesterol levels from creeping up again and causing build up of fatty deposits. However, you should stop if your doctor tells you to do so, or you have become pregnant.What you need to know before you take Rosutin®Do not take Rosutin®:If you have ever had an allergic reaction to Rosutin®, or to any of its ingredients.If you are pregnant or breast-feeding. If you become pregnant while taking Rosutin® stop taking it immediately and tell your doctor. Women should avoid becoming pregnant while taking Rosutin® by using suitable contraception.If you have liver disease.If you have severe kidney problems.If you have repeated or unexplained muscle aches or pains.If you take a drug called ciclosporin (used, for example, after organ transplants)If any of the above applies to you (or you are in doubt), please go back and see your doctor.Warnings and precautionsTalk to your doctor or pharmacist before taking Rosutin®.If you have problems with your kidneys.If you have problems with your liver.If you have had repeated or unexplained muscle aches or pains, a personal or family history of muscle problems, or a previous history of muscle problems when taking other cholesterol-lowering medicines. Tell your doctor immediately if you have unexplained muscle aches or pains especially if you feel unwell or have a fever. Also tell your doctor or pharmacist if you have a muscle weakness that is constant.If you regularly drink large amounts of alcohol.If your thyroid gland is not working properly.If you take other medicines called fibrates to lower your cholesterol. Please read this leaflet carefully, even if you have taken other medicines for high cholesterol before.If you take medicines used to treat the HIV infection e.g. ritonavir with lopinavir and/or atazanavir.If you take antibiotics containing fusidic acid, please see Other medicines and Rosutin®.Children and adolescentsIf the patient is under 6 years old: Rosutin® should not be given to children younger than 6 years.If the patient is below 18 years of age: The Rosuvastatin 40 mg tablet is not suitable for use in children and adolescents below 18 years of age.If you are over 70 (as your doctor needs to choose the right start dose of Rosutin® to suit you)If you have severe respiratory failure.If you are of Asian origin - that is Japanese, Chinese, Filipino, Vietnamese, Korean and Indian. Your doctor needs to choose the right start dose of Rosutin® to suit you.If any of the above applies to you (or if you are not sure):Do not take Rosuvastatin 40 mg (the highest dose) and check with your doctor or pharmacist before you actually start taking any dose of Rosutin®.In a small number of people, statins can affect the liver. This is identified by a simple test which looks for increased levels of liver enzymes in the blood. For this reason, your doctor will usually carry out this blood test (liver function test) before and during treatment with Rosutin®.While..
Available for request
Rosuva 10 mg tablet
Indication:Heterozygous HypercholesterolemiaHomozygous HypercholesterolemiaMixed DyslipidemiaDosage & Administration:Rosuvastatin can be taken with or without food, at any time of day. Dose range: 5-40 mg once daily.Preparation:RosuvaTM 5 Tablet: Each box contains 50 film coated tablets in blister pack.RosuvaTM 10 Tablet: Each box contains 30 film coated tablets in blister pack.RosuvaTM 20 Tablet: Each box contains 20 film coated tablets in blister pack...
Available for request
Rosuva 20 mg tablet
Indication:Heterozygous HypercholesterolemiaHomozygous HypercholesterolemiaMixed DyslipidemiaDosage & Administration:Rosuvastatin can be taken with or without food, at any time of day. Dose range: 5-40 mg once daily.Preparation:RosuvaTM 5 Tablet: Each box contains 50 film coated tablets in blister pack.RosuvaTM 10 Tablet: Each box contains 30 film coated tablets in blister pack.RosuvaTM 20 Tablet: Each box contains 20 film coated tablets in blister pack...
Available for request
Rosuva 5 mg tablet
Indication:Heterozygous HypercholesterolemiaHomozygous HypercholesterolemiaMixed DyslipidemiaDosage & Administration:Rosuvastatin can be taken with or without food, at any time of day. Dose range: 5-40 mg once daily.Preparation:RosuvaTM 5 Tablet: Each box contains 50 film coated tablets in blister pack.RosuvaTM 10 Tablet: Each box contains 30 film coated tablets in blister pack.RosuvaTM 20 Tablet: Each box contains 20 film coated tablets in blister pack...
Available for request
