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Adrinor 1mg 1 ml Injection

Adrinor 1mg 1 ml Injection

IndicationsAdjunctive use in the management of cardiac arrest. It is used in cardiopulmonary resuscitation. Intracardiac puncture and intramyocardial injection of adrenaline may be effective when external cardiac compression and attempts to restore the circulation by electrical defibrillation or use of a pacemaker fail. Adrenaline is a drug that leads to increased blood pressure, increased heart rate, increased air entry, increased blood glucose, stimulates cardiac activity and reduces allergic reactions by reducing inflammatory response caused by histamine. Due to these properties, it is used for the treatment of allergic and anaphylactic reactions. Adrenaline is the favored treatment for anaphylactic shock and should be administered immediately if a person begins exhibiting severe allergic reactions. Adrenaline is also used in life threatening asthma when failing ventilation and continued deterioration despite nebulizer therapy.DescriptionsAdrenaline is a direct-acting sympathomimetic agent exerting its effect on alpha and beta-adrenoceptors. The overall effect of adrenaline depends on the dose, and may be complicated by the homeostatic reflex responses. In resuscitation procedures it is used to increase the efficacy of basic life support. It is a positive cardiac inotrope. Major effects are increased systolic blood pressure by arterioral and venous vasoconstriction (alpha1 effects), reduced diastolic pressure, tachycardia and hyperglycaemia. Adrenaline is rapid in onset and with short duration. After IV infusion the half-life is approximately 5-10 minutes. It is rapidly distributed to the heart, spleen, several glandular tissues and adrenergic nerves. Adrenaline is rapidly metabolised in the liver and tissues by oxidative de-amination and O-methylation followed by reduction or by conjugation with glucuronic acid or sulphate. Up to 90% of the IV dose is excreted in the urine as metabolites. It is approximately 50% bound to plasma proteins.Dosage & AdministrationCardiac arrest: 1. Intravenous injection: 1 mg injection repeated every 2-3 minutes as necessary. 2. Endotracheal: 2-3 mg via an endotracheal tube, repeated as necessary. 3. Intracardiac injection: 0.1 to 1 mg, direct into the atrium of the heart. 4. Intraspinal use: Usual dose is 0.2 to 0.4 mg added to anesthetic spinal fluid mixture (to prolong anesthetic action by limiting absorption). Anaphylaxis, asthma or severe bronchospasm: Adult dose is 0.25 - 0.5 mg. It may be repeated at 5 minutes intervals until perfusion and respiratory status normalizes. In case of dose dilution: 1 mg of Adrenaline to be diluted in 9 ml Normal Saline. Children: Intravenous injection: Initially 10 mcg/kg body weight, not to exceed 250 mcg. May be repeated every 3-5 minutes if necessary. Subsequent doses should be 100 mcg/kg.Side EffectsAnxiety, restlessness, dizziness, headache, palpitations, rapid pulse, tremors, weakness and coldness of the extremities may be reported even with small doses and especially when given in conjunction with local anaesthetics.PrecautionsThe solution should not be used if it is pinkish or darker than slightly yellow or if it contains a precipitate. Adrenaline is readily destroyed by alkalies and oxidizing agents. In the latter category are Oxygen, Chlorine, Iodine, Permanganates, Chromates, Nitrites and salts of easily reducible metals, especially Iron. Adrenaline should not be mixed with Sodium bicarbonate; the solution is oxidised to adrenochrome and then forms polymers. Special warnings and precautions for use Administer slowly with caution to elderly patients and to patients with ischemic heart disease, hypertension, diabetes mellitus, hyperthyroidism or psychoneurosis. Use with extreme caution in patients with long-standing bronchial asthma and emphysema who have developed degenerative heart disease. Anginal pain may be induced when coronary insufficiency is present.ContraindicationsHypertension, arteriosclerosis, coronary disease and hyperthyroidism. Not to be given to patients taking monoamine oxidase inhibitors.Use in Pregnancy & LactationPregnancy Category C. It crosses the placenta and is excreted in breast milk. Adrenaline should only be used in pregnancy if the potential benefits outweigh the risks to the fetus. Lactating mothers: It is excreted in breast milk and therefore Adrenaline is not recommended for use during lactation because of the risk of adverse effects of infants.Drug InteractionUse of Adrenaline with excessive doses of digitalis, mercurial diuretics or other drugs that sensitize the heart to arrhythmias is not recommended. The adverse effects of Adrenaline may be potentiated by tricyclic antidepressants; certain antihistamines; e.g, Diphenhydramine, Tripelennamine, Chlorpheniramine and L-thyroxine Sodium.OverdoseSymptoms: Cardiac arrhythmia leading to ventricular fibrillation, severe hypertension leading to pulmonary edema and cerebral hemorrhage. Treatmen..

Tk.25.00/=

  0 отзывов

Aeron 10 tablet

Aeron 10 tablet

Aeron 10 tablet..

Tk.15.00/=

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Aeron FT 4mg tablet

Aeron FT 4mg tablet

Aeron FT 4mg tablet..

Tk.6.00/=

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Aeron FT 5mg tablet

Aeron FT 5mg tablet

Aeron FT 5mg tablet..

Tk.8.00/=

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Alarid Tablet 1 mg

Alarid Tablet 1 mg

Alarid Tablet 1 mg Indication:• Prophylactic treatment of bronchial asthma• Symptomatic treatment of allergic conditions including rhinitis and conjunctivitisDosage & Administration:Adults: 1 mg twice daily with food. If necessary, the dose may be increased to 2 mg twice daily in severe cases.Children above 3 years: 1 mg twice daily with food. Patients known to be easily sedated should begin treatment with 0.5 to 1 mg at night for the first few days or as directed by the physician.Use in elderly: Same as adult dose or as advised by the physician.Preparation:Alarid® Tablet: Each box contains 100’s tablets in blister pack.Alarid® Syrup: Each PET bottle contains 100 ml syrup and a measuring cup...

Tk.2.50/=

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Alatrol 10mg tab

Alatrol 10mg tab

Indication: Alatrol® is indicated for the relief of symptoms associated with seasonal allergic rhinitis due to allergen. Symptoms treated effectively include sneezing, rhinorrhea, pruritus, ocular pruritus, tearing and redness of the eyes. Alatrol® is indicated for the relief of symptoms associated with perennial allergic rhinitis due to allergens. Symptoms treated effectively include sneezing, rhinorrhea, post-nasal discharge, nasal pruritus, ocular pruritus and tearing. Alatrol® is indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria. It is also used in allergen induced asthma.Dosage & Administration:Alatrol® is administered with or without food. Adults and Children 6 years and older: ..

Tk.3.01/=

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Alatrol 60ml Syp

Alatrol 60ml Syp

Indication: Alatrol® is indicated for the relief of symptoms associated with seasonal allergic rhinitis due to allergen. Symptoms treated effectively include sneezing, rhinorrhea, pruritus, ocular pruritus, tearing and redness of the eyes. Alatrol® is indicated for the relief of symptoms associated with perennial allergic rhinitis due to allergens. Symptoms treated effectively include sneezing, rhinorrhea, post-nasal discharge, nasal pruritus, ocular pruritus and tearing. Alatrol® is indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria. It is also used in allergen induced asthma.Dosage & Administration:Alatrol® is administered with or without food. Adults and Children 6 years and older: ..

Tk.30.10/=

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Alben 10ml susp.

Alben 10ml susp.

Alben 10ml susp...

Tk.20.00/=

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Alben 200

Alben 200

Alben 200..

Tk.20.00/=

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Alben DS 400

Alben DS 400

Alben DS 400..

Tk.5.00/=

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Alben DS 400 tablet

Alben DS 400 tablet

Alben DS 400 tablet..

Tk.5.00/=

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Alentin DS 400

Alentin DS 400

Alentin DS 400..

Tk.3.35/=

  0 отзывов

Algin 50mg Tab

Algin 50mg Tablet

Algin 50mg Tablet..

Tk.8.00/=

  0 отзывов

ALGIN 50ML SYRP

ALGIN 50ML SYRP

Algin..

Tk.55.00/=

  1 отзывов

Almex 400 mg Tablet

Almex 400 mg Tablet

Indication: Single or mixed intestinal infections caused by various helminths.Dosage & Administration:12 to 24 months: 200 mg as a single dose (Half of Almex® 400 tablet or 5 ml Almex® suspension). Adults & children (over 2 years): Ascariasis, enterobiasis, trichuriasis & hookworm infestation - 400 mg (One Almex® 400 tablet or 10 ml Almex® suspension) single dose. Strogyloidiasis or taeniasis - 400 mg once daily for three consecutive days. Giardiasis - 400 mg once daily for five days. Hydatid disease (Echinococcosis)-400 mg twice daily for 28 days. For cystic echinococcosis the 28-days course may be repeated after 14 days without treatment to a total of three treatment cycles. For alveolar echinococcosis, 400 mg twice daily for 28 days followed by 14 days wShow more Preparation: Almex® 400 Tablet: Each box contains 12×4’s tablets in blister pack. ..

Tk.5.02/=

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Almitan 6.25 mg tab

Almitan 6.25 mg tab

Almitan 6.25 mg tab..

Tk.25.00/=

  0 отзывов

Alneed Capsule

Alneed Capsule

DescriptionAlneed is a special preparation of Iron, Folic acid, B-vitamins and Vitamin-C.IndicationsAlneed is indicated for the treatment and prophylaxis of Iron, Folic acid, B-vitamins and Vitamin-C deficiency, especially during pregnancy and lactation.Dosage & AdministrationOne capsule daily. In more severe cases, 2 capsules a day may be required or as directed by the physician.Side EffectsGenerally well tolerated. However, a few allergic reactions may be seen.PrecautionsCare should be taken in patients who may develop iron overload, such as those with hemochromatosis, haemolytic anaemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.Use in Pregnancy & LactationRecommended.Over DoseAccidental overdose of iron containing products is a leading cause of fatal poisoning in children fewer than 6. Avoid higher doses if you have liver disease or hemochromatosis; excess can cause bloody diarrhea, vomiting, acidosis, darkened stools, abdominal pain. Symptoms may clear in a few hours. Riboflavin is reported to be completely safe and no toxic symptoms have been reported so far. Higher doses of Nicotinamide may cause vomiting, diarrhea. Sensory neuropathy was observed in individuals consuming more than 200 mg Pyridoxine for very long periods. No cases of Folic acid overdosages have been reported. Acute ingestion of Ascorbic acid, even of massive doses, is unlikely to cause significant effects.StorageStore in a dry place below 25 °C. Protect from light...

Tk.3.00/=

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Alneed PLUS Cap

Alneed PLUS Cap

DescriptionAlneed Plus is a special preparation of Zinc, Iron, Folic Acid, B-vitamins and Vitamin-C.IndicationsAlneed Plus is indicated for the treatment and prophylaxis of Zinc, Iron, Folic Acid, B-vitamins and Vitamin-C deficiency especially during pregnancy and lactation.Dosage & AdministrationOne capsule daily. In more severe cases, 2 capsules a day may be required or as directed by the physician.Side EffectsGenerally well tolerated. However, a few allergic reactions may be seen.PrecautionsCare should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anaemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.Use in Pregnancy & LactationRecommended.Over DoseAccidental overdose of iron containing products is a leading cause of fatal poisoning in children below 6 years. Avoid higher doses if you have liver disease or haemochromatosis; excess can cause bloody diarrhea, vomiting, acidosis, darkened stools, abdominal pain. Symptoms may clear in a few hours.Riboflavin is reported to be completely safe and no toxic symptoms have been reported so far. Higher doses of Nicotinamide may cause vomiting, diarrhea. Sensory neuropathy was observed in individuals consuming more than 200 mg Pyridoxine for very long periods. No case of Folic acid overdodage has been reported.Acute ingestion of Ascorbic acid, even of massive doses, is unlikely to cause significant effects.Zinc toxicity has been seen in both acute and chronic forms. Ingestion of 150 to 450 mg of zinc per day have been associated with low copper status, altered iron function, reduced immune function, and reduced levels of high-density lipoproteins. So, Zinc at its RDA dosages dose not cause any significant effect.StorageStore in a dry place below 25 °C. Protect from light...

Tk.3.50/=

  0 отзывов

Alphapress 1 mg Tablet

Alphapress 1 mg Tablet

Alphapress 1 mg Tablet..

Tk.4.00/=

  0 отзывов

Alphin DS

Alphin DS

Alphin® DS (Albendazole) is a broad spectrum anthelmintic available as chewable tablets, each containing 400 mg of Albendazole USP. It is a very potent benzimidazole carbamate anthelmintic used in the treatment of various intestinal worm infestations and hydatid disease.Broad spectrum anthelmintic for better efficacy Broad spectrum of activity against wide range of helminthesEnsures successful dewormingEnsures safety to the treatmentExcellent chocolate taste ensures superb patient satisfaction..

Tk.5.00/=

  0 отзывов

Alprax 0.25 tablet

Alprax 0.25 tablet

Alprax 0.25 tablet..

Tk.1.00/=

  0 отзывов

Alprax 0.5 tablet

Alprax 0.5 tablet

Alprax 0.5 tablet..

Tk.2.01/=

  0 отзывов

Alprax XR 1mg tab

Alprax XR 1mg tab

Alprax XR 1mg tab..

Tk.4.03/=

  0 отзывов

Alprax XR 2mg tab

Alprax XR 2mg tab

Alprax XR 2mg tab..

Tk.8.06/=

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Altrip 6.25 mg Tablet, 1 strip

Altrip 6.25 mg Tablet, 1 strip

Altrip 6.25 mg Tablet, 1 stripDescription:Almotriptan is a selective and potent serotonin (5-HT1B/1D) agonist. Almotriptan binds to specific serotonin receptors on meningeal arteries inhibiting the release of vasoactive peptides and causing constriction of the arteries. It has a limited effect on arteries supplying blood to the brain and little effect on cardiac and pulmonary vessels.ndicationAlmotriptan is prescribed to treat the acute headache phase of migraine attacks with or without aura. Almotriptan is the only oral triptan approved in the USA for the treatment of migraine in adolescent from 12 to 17 years of age.Dosage & AdministrationAcute Treatment of Migraine Attacks: The recommended dose of Altrip in adults and adolescents age 12 to 17 years is 6.25 mg to 12.5 mg, with the 12.5 mg dose tending to be a more effective dose in adults. If the headache is relieved after the initial Altrip (almotriptan malate) dose but returns, the dose may be repeated after 2 hours. The maximum daily dose should not exceed 25 mg. The safety of treating an average of more than four migraines in a 30-day period has not been established.Hepatic Impairment:The recommended starting dose of almotriptan malate in patients with hepatic impairment is 6.25 mg. The maximum daily dose should not exceed 12.5 mg over a 24-hour periodRenal Impairment:The recommended starting dose of almotriptan malate in patients with severe renal impairment is 6.25 mg. The maximum daily dose should not exceed 12.5 mg over a 24-hour periodContraindicationAs with other 5-HT1B/1D receptor agonists, almotriptan should not be used in patients with a history, symptoms or signs of ischaemic heart disease (myocardial infarction, angina pectoris, documented silent ischaemia, Prinzmetals angina) or severe hypertension and uncontrolled mild or moderate hypertension. Concomitant administration with ergotamine, ergotamine derivatives (including methysergide) and other 5-HT1B/1D agonists is contraindicated.PrecautionHypersensitivity to the active substance or to any of the excipients. Patients with severe hepatic impairment, with a previous cerebrovascular accident (CVA) or transient ischaemic attack (TIA) Peripheral vascular diseaseSide EffectsSerious cardiac reactions, including myocardial infarction, have occurred following the use of almotriptan malate Tablets. These reactions are extremely rare and most have been reported in patients with risk factors predictive of CAD (Coronary Artery Disease).Drug InteractionThese drugs have been reported to cause prolonged vasospastic reactions. Cases of life-threatening serotonin syndrome have been reported during combined use of triptans and selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs).OverdoseNo case of overdose has been reported. The most frequently reported adverse event in patients receiving 150 mg (the highest dose administered to patients) was somnolence.Pregnancy & LactationPregnancy Category C. There is no data regarding excretion of almotriptan in human milk.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...

Tk.250.80/=

  0 отзывов

Alucil S Suspension

Alucil S Suspension

Alucil S..

Tk.80.00/=

  0 отзывов

Alucil S Tab

Alucil S Tab

Alucil S..

Tk.2.00/=

  0 отзывов

Alzed 400mg Tablet

Alzed 400mg Tablet

Alzed 400..

Tk.3.32/=

  0 отзывов

Alzolam 0.25 Tab

Alzolam 0.25 Tab

Alzolam 0.25 Tab..

Tk.1.50/=

  0 отзывов

Alzolam 0.5 tab

Alzolam 0.5 tab

Alzolam 0.5 tab..

Tk.3.00/=

  0 отзывов

Ambrox 100ml Syrup

Ambrox 100ml Syrup

Ambrox SyrupIndicationsAcute and chronic diseases of respiratory tracts associated with viscid mucus including acute and chronic bronchitisProductive coughInflammatory diseases of Rhinopharyngeal tract (e.g. Laryngitis, Pharyngitis, Sinusitis and Rhinitis) associated with viscid mucusAsthmatic bronchitis, Bronchial asthma with difficult departure of mucusBronchiectasisChronic pneumonia.Therapeutic ClassCough expectorants & mucolyticsPharmacologyAmbroxol is a metabolite of Bromhexine. It possesses mucokinetic (improvement in mucus transport) and secretolytic (liquefies secretions) properties. Ambroxol stimulates the serous cells of the glands of the mucous membrane of bronchi, increasing the content of mucus secretion. The mucolytic effect is associated with depolymerization and splitting of mucoproteins and mucopolysaccharide fibres, which leads to reduction in the viscosity of mucus. Expectoration of mucus is facilitated and breathing is eased considerably. Ambroxol stimulates production of phospholipids of surfactant by alveolar cells. Ambroxol has anti-inflammatory properties. In patients with COPD, it improves airway patency. Beside these, Ambroxol also exhibits anti oxidant activity. Long-term use is possible because of the good tolerability of the preparation.Dosage & AdministrationAverage daily dose (preferably after meal):Syrup:2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day5-10 years: 5 ml (1 teaspoonful) 2-3 times a day10 years and adults: 10 ml (2 teaspoonful) 3 times a day.Sustained release capsule:Adult and children over 12 years old: 1 capsule once dailySpecific application features: Ambroxol may be prescribed to patients suffering from diabetes mellitus.InteractionAmbroxol has no interaction with cardioactive glycosides, corticosteroids, bronchodilators, diuretics and antibiotics (normally used in the treatment of bronchopulmonary affections). But Ambroxol should not be taken simultaneously with antitussives (e.g. Codeine) because mucus, which has been liquefied by Ambroxol, might not be expectorated.ContraindicationsContraindicated in known hypersensitivity to Ambroxol or Bromhexine.Side EffectsGastrointestinal side-effects like epigastric pain, gastric fullness may occur occasionally. Rarely allergic responses such as eruption, urticaria or angioneurotic edema may occur...

Tk.50.00/=

  0 отзывов

Amdocal 10 Tab

Amdocal 10 Tab

Amdocal 10 Tab1. What Amdocal is and what it is used for?Amdocal® (Amlodipine) is a dihydropyridine calcium antagonist, with a long duration of action, used for the treatment of hypertension and angina pectoris.2. Before you take AmdocalDo not take this medicine and tell your doctor if:Amlodipine is contraindicated in patients with known hypersensitivity to Amlodipine.Do not take this medicine if the above applies to you. If you are not sure, talk to your doctor before taking Amdocal.Take special care with AmdocalCaution should be exercised when administering Amlodipine with any other peripheral vasodilator particularly in patients with severe aortic stenosis. Although haemodynamic studies and a controlled trial in Class-II-III heart failure patients have shown that Amlodipine did not lead to clinical deterioration as measured by exercise tolerance, left ventricular ejection fraction and clinical symptomatology in general, all calcium channel blockers should be used with caution in patients with heart failure.Amlodipine gives no protection against the danger of abrupt beta-blocker withdrawal; any such withdrawal should be gradual reduction of the dose of beta-blocker. Since Amlodipine is extensively metabolized by the liver, so caution should be exercised when administering Amlodipine to patients with hepatic impairment.Taking other medicinesNo significant drug interactionPregnancy and breast-feedingNo relevant data is available.How to take Amdocal?The usual initial antihypertensive oral dose is 5mg once daily with a maximum dose of 10 mg once daily. Elderly individuals or patients with hepatic insufficiency may be started with 2.5 mg once daily dose and this dose may be used when adding Amdocal® to other antihypertensive therapy.Dosage should be adjusted according to each patient′s need.The recommended dose for stable or vasospastic angina is 5-10 mg, with the lower dose suggested in the elderly and in patients with hepatic insufficiency.Always use Amdocal exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.If you take more Amdocal than you shouldIn humans, experience with intentional overdosage of Amlodipine is limited. If massive overdosage occurs, active cardiac and respiratory monitoring should be instituted. Frequent blood pressure measurements are essential.If you forget to take AmdocalIf you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten doseIf you stop taking AmdocalDo not stop taking this medicine without talking to your doctor. You should not stop taking Amdocal just because you feel better. This is because the problem may come back or get worse again.If you have any further questions on the use of this product, ask your doctor or pharmacist.3. Possible side effectsLike all medicines, Amdocal can cause side effects, although not everybody gets them.Peripheral oedema may occasionally be severe but is fully reversible. As with other calcium antagonist drugs, peripheral oedema and skin erythema occur in a proportion of patients (5-10%) and facial flushing in 2-5% of patients. Complaint of fatigue was also reported more frequently than in placebo-treated patients.There is evidence that these effects are more common in patients treated with doses greater than 10 mg daily.Tell your doctor if any of the side effects gets serious or lasts longer than a few days, or if you notice any side effects not listed in this leaflet4. How to store AmdocalStore below 25°C. Protect from light. Keep out of reach of children...

Tk.7.00/=

  0 отзывов

Amdocal 5 Tablet

Amdocal 5 Tablet

Amdocal 5 Tablet1. What Amdocal is and what it is used for?Amdocal® (Amlodipine) is a dihydropyridine calcium antagonist, with a long duration of action, used for the treatment of hypertension and angina pectoris.2. Before you take AmdocalDo not take this medicine and tell your doctor if:Amlodipine is contraindicated in patients with known hypersensitivity to Amlodipine.Do not take this medicine if the above applies to you. If you are not sure, talk to your doctor before taking Amdocal.Take special care with AmdocalCaution should be exercised when administering Amlodipine with any other peripheral vasodilator particularly in patients with severe aortic stenosis. Although haemodynamic studies and a controlled trial in Class-II-III heart failure patients have shown that Amlodipine did not lead to clinical deterioration as measured by exercise tolerance, left ventricular ejection fraction and clinical symptomatology in general, all calcium channel blockers should be used with caution in patients with heart failure.Amlodipine gives no protection against the danger of abrupt beta-blocker withdrawal; any such withdrawal should be gradual reduction of the dose of beta-blocker. Since Amlodipine is extensively metabolized by the liver, so caution should be exercised when administering Amlodipine to patients with hepatic impairment.Taking other medicinesNo significant drug interactionPregnancy and breast-feedingNo relevant data is available.How to take Amdocal?The usual initial antihypertensive oral dose is 5mg once daily with a maximum dose of 10 mg once daily. Elderly individuals or patients with hepatic insufficiency may be started with 2.5 mg once daily dose and this dose may be used when adding Amdocal® to other antihypertensive therapy.Dosage should be adjusted according to each patient′s need.The recommended dose for stable or vasospastic angina is 5-10 mg, with the lower dose suggested in the elderly and in patients with hepatic insufficiency.Always use Amdocal exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.If you take more Amdocal than you shouldIn humans, experience with intentional overdosage of Amlodipine is limited. If massive overdosage occurs, active cardiac and respiratory monitoring should be instituted. Frequent blood pressure measurements are essential.If you forget to take AmdocalIf you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten doseIf you stop taking AmdocalDo not stop taking this medicine without talking to your doctor. You should not stop taking Amdocal just because you feel better. This is because the problem may come back or get worse again.If you have any further questions on the use of this product, ask your doctor or pharmacist.3. Possible side effectsLike all medicines, Amdocal can cause side effects, although not everybody gets them.Peripheral oedema may occasionally be severe but is fully reversible. As with other calcium antagonist drugs, peripheral oedema and skin erythema occur in a proportion of patients (5-10%) and facial flushing in 2-5% of patients. Complaint of fatigue was also reported more frequently than in placebo-treated patients.There is evidence that these effects are more common in patients treated with doses greater than 10 mg daily.Tell your doctor if any of the side effects gets serious or lasts longer than a few days, or if you notice any side effects not listed in this leaflet4. How to store AmdocalStore below 25°C. Protect from light. Keep out of reach of children...

Tk.5.00/=

  0 отзывов

Amdocal PLUS 25 Tablet

Amdocal PLUS 25 Tablet

Amdocal PLUS 25 Tablet1. What Amdocal Plus is and what it is used for?Amdocal Plus® is a fixed dose combination of Amlodipine Besilate and Atenolol. Amlodipine Besilate is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Atenolol is (2-Hydroxy-3-isopropyl- aminopropoxy) phenylacetamide, a selective b1 blocker. Amdocal Plus used in the treatment of Hypertension not controlled by monotherapy, Angina pectoris & hypertension co-existing diseases, Post M.I patients. Refractory angina pectoris where nitrate therapy has failed.2. Before you take Amdocal PlusDo not take this medicine and tell your doctor if:Amlodipine is contraindicated in patients with a known sensitivity to dihydropyridines. It should not be used in cardiogenic shock, clinically significant aortic stenosis, unstable angina (excluding Prinzmetal’s angina). Atenolol is contraindicated with a known hypersensitivity to Atenolol, severe bradycardia, second degree or the third degree heart block, uncontrolled heart failure, hypotension, severe peripheral vascular disease (including intermittent claudication), sick sinus syndrome, cardiogenic shock, phaeocromocytoma (without a concommitant alpha blocker), metabolic acidosis. Do not take this medicine if the above applies to you. If you are not sure, talk to your doctor before taking Amdocal Plus.Take special care with Amdocal PlusAtenolol may mask the symptoms of hyperthyroidism. It may also mask the symptoms of hypoglycaemia, as well as enhancing the effects of hypoglycemic agents in patients with diabetes mellitus.Taking other medicinesAtenolol: The effects of other myocardial depressant agents, including anti-arrhythmics such as Quinidine, Procainamide, or Lignocaine, Phenytoin, and medicines which interfere with calcium transport, such as Verapamil, may also be enhanced by Atenolol.The effects of Atenolol are diminished by beta-adrenoceptor stimulating agents such as Isoprenaline; the hypotensive effects of Atenolol may be dangerously reversed and the peripheral vasoconstrictor effects enhanced by alpha-adrenoceptor stimulating agents such as noradrenaline or those with mixed alpha- and beta-adrenoceptor stimulating properties such as adrenaline; bradycardia may also occur.The effects of Atenolol may be enhanced by adrenergic neuron blocking agents such as Guanethidine or Bethanidine, or Catecholamine-depleting agents such as Reserpine and the hypotensive effects by diuretics. Atenolol may enhance some of the cardiac effects of digitalis and diminish others. It has been suggested that clonidine withdrawal symptoms may be exacerbated in patients who are concurrently taking a beta blocker.Pregnancy and breast-feedingAtenolol crosses the placenta. So it is contraindicated in pregnancy and lactation.3. How to take Amdocal Plus?The recommended dosage is one tablet of Amdocal Plus® 50 (Amlodipine 5mg and Atenolol 50mg) or Amdocal Plus® 25 (Amlodipine 5mg and Atenolol 25 mg). Depending upon the therapeutic response, titration of the dosage is recommended. In elderly patients, it is advisable to initiate the therapy with 1/2 tablet of fixed dose combination of Amlodipine & Atenolol i.e. 2.5 mg Amlodipine & 25 mg Atenolol.If you take more Amdocal Plus than you shouldIn humans, experience with intentional overdosage of Amlodipine is limited. If massive overdosage occurs, active cardiac and respiratory monitoring should be instituted. Frequent blood pressure measurements are essential.If you forget to take Amdocal PlusIf you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten doseIf you stop taking Amdocal PlusDo not stop taking this medicine without talking to your doctor. You should not stop taking Amdocal Plus just because you feel better. This is because the problem may come back or get worse again.If you have any further questions on the use of this product, ask your doctor or pharmacist.4. Possible side effectsLike all medicines, Amdocal Plus can cause side effects, although not everybody gets them.Amlodipine: Peripheral edema may occasionally be present but is fully reversible. As with other calcium channel blockers peripheral edema and skin erythema occur in a proportion of patients and facial flushing occurs in 2-5% of patients. Complaints of fatigue were also reported more frequently than in placebo-treated patients. There is evidence that these effects are more common in patients treated with doses greater than 10 mg daily.Atenolol: Pronounced fatigue and cold extremities have been observed in 10 to 20% of the treated subjects. Complaints about bradycardia, dizziness and gastrointestinal symptoms are less frequent. Despite its relative selectivity, Atenolol can cause bronchospasms in asthma patients.Tell your doctor if any of the side effects gets serious..

Tk.5.25/=

  0 отзывов

Amdocal PLUS 50 Tablet

Amdocal PLUS 50 Tablet

Amdocal PLUS 50 Tablet1. What Amdocal Plus is and what it is used for?Amdocal Plus® is a fixed dose combination of Amlodipine Besilate and Atenolol. Amlodipine Besilate is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Atenolol is (2-Hydroxy-3-isopropyl- aminopropoxy) phenylacetamide, a selective b1 blocker. Amdocal Plus used in the treatment of Hypertension not controlled by monotherapy, Angina pectoris & hypertension co-existing diseases, Post M.I patients. Refractory angina pectoris where nitrate therapy has failed.2. Before you take Amdocal PlusDo not take this medicine and tell your doctor if:Amlodipine is contraindicated in patients with a known sensitivity to dihydropyridines. It should not be used in cardiogenic shock, clinically significant aortic stenosis, unstable angina (excluding Prinzmetal’s angina). Atenolol is contraindicated with a known hypersensitivity to Atenolol, severe bradycardia, second degree or the third degree heart block, uncontrolled heart failure, hypotension, severe peripheral vascular disease (including intermittent claudication), sick sinus syndrome, cardiogenic shock, phaeocromocytoma (without a concommitant alpha blocker), metabolic acidosis. Do not take this medicine if the above applies to you. If you are not sure, talk to your doctor before taking Amdocal Plus.Take special care with Amdocal PlusAtenolol may mask the symptoms of hyperthyroidism. It may also mask the symptoms of hypoglycaemia, as well as enhancing the effects of hypoglycemic agents in patients with diabetes mellitus.Taking other medicinesAtenolol: The effects of other myocardial depressant agents, including anti-arrhythmics such as Quinidine, Procainamide, or Lignocaine, Phenytoin, and medicines which interfere with calcium transport, such as Verapamil, may also be enhanced by Atenolol.The effects of Atenolol are diminished by beta-adrenoceptor stimulating agents such as Isoprenaline; the hypotensive effects of Atenolol may be dangerously reversed and the peripheral vasoconstrictor effects enhanced by alpha-adrenoceptor stimulating agents such as noradrenaline or those with mixed alpha- and beta-adrenoceptor stimulating properties such as adrenaline; bradycardia may also occur.The effects of Atenolol may be enhanced by adrenergic neuron blocking agents such as Guanethidine or Bethanidine, or Catecholamine-depleting agents such as Reserpine and the hypotensive effects by diuretics. Atenolol may enhance some of the cardiac effects of digitalis and diminish others. It has been suggested that clonidine withdrawal symptoms may be exacerbated in patients who are concurrently taking a beta blocker.Pregnancy and breast-feedingAtenolol crosses the placenta. So it is contraindicated in pregnancy and lactation.3. How to take Amdocal Plus?The recommended dosage is one tablet of Amdocal Plus® 50 (Amlodipine 5mg and Atenolol 50mg) or Amdocal Plus® 25 (Amlodipine 5mg and Atenolol 25 mg). Depending upon the therapeutic response, titration of the dosage is recommended. In elderly patients, it is advisable to initiate the therapy with 1/2 tablet of fixed dose combination of Amlodipine & Atenolol i.e. 2.5 mg Amlodipine & 25 mg Atenolol.If you take more Amdocal Plus than you shouldIn humans, experience with intentional overdosage of Amlodipine is limited. If massive overdosage occurs, active cardiac and respiratory monitoring should be instituted. Frequent blood pressure measurements are essential.If you forget to take Amdocal PlusIf you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten doseIf you stop taking Amdocal PlusDo not stop taking this medicine without talking to your doctor. You should not stop taking Amdocal Plus just because you feel better. This is because the problem may come back or get worse again.If you have any further questions on the use of this product, ask your doctor or pharmacist.4. Possible side effectsLike all medicines, Amdocal Plus can cause side effects, although not everybody gets them.Amlodipine: Peripheral edema may occasionally be present but is fully reversible. As with other calcium channel blockers peripheral edema and skin erythema occur in a proportion of patients and facial flushing occurs in 2-5% of patients. Complaints of fatigue were also reported more frequently than in placebo-treated patients. There is evidence that these effects are more common in patients treated with doses greater than 10 mg daily.Atenolol: Pronounced fatigue and cold extremities have been observed in 10 to 20% of the treated subjects. Complaints about bradycardia, dizziness and gastrointestinal symptoms are less frequent. Despite its relative selectivity, Atenolol can cause bronchospasms in asthma patients.Tell your doctor if any of the side effects gets serious..

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Amdova

Amdova

1. What Amdova is and what it is used for? Amdova® is a combination product containing Amlodipine Besilate BP equivalent to 5 mg Amlodipine, a calcium channel blocker and Atorvastatin calcium INN equivalent to 10 mg Atorvastatin, a statin (HMG-CoA reductase inhibitor). Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure. Atorvastatin calcium is a synthetic lipid-lowering agent. It is an inhibitor of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA). This enzyme catalyzes the conversion of HMG-CoA to mevatonate, an early and rate limiting step in the synthesis of cholesterol.Patients in whom treatment with Amlodipine and Atorvastatin is appropriate at the dose presented, which include hypertension, chronic stable angina, an adjunct to diet for hypercholesterolemia and in hypertensive patient with multiple risk factors for CHD to reduce the risk of non fatal MI and non fatal stroke. 2. Before you take Amdova Do not take this medicine and tell your doctor if: Amlodipine is contraindicated in patients with known hypersensitivity to Amlodipine. Atorvastatin is contraindicated in hypersensitivity to any component of this medication. Active liver disease or unexplained persistent elevations of serum transaminases exceeding three times the upper limit of normal. Do not take this medicine if the above applies to you. If you are not sure, talk to your doctor before taking Amdova. Take special care with AmdovaSince the vasodilatation induced by Amlodipine is gradual in onset, acute hypotension has rarely been reported after oral administration of Amlodipine. Nonetheless, caution should be exercised when administering Amlodipine as with any other peripheral vasodilator particularly in patients with severe aortic stenosis. Use in Patients with Congestive Heart Failure: Although hemodynamic studies and a controlled trial in Class-II-III heart failure patients have shown that amlodipine did not lead to clinical deterioration as measured by exercise tolerance, left ventricular ejection fraction, and clinical symptoms. In general, all calcium channel blockers should be used with caution in patients with heart failure. Rhabdomyolysis with acute renal failure secondary to myoglobinuria has been reported with other drugs in the statin class. Atorvastatin may cause an elevation in serum creatine phosphokinase levels. This should be considered in the differential diagnosis of chest pain in patients on therapy with Atorvastatin. Uncomplicated myalgia has been reported in Atorvastatin-treated patients. Atorvastatin therapy should be discontinued if markedly elevated CPK levels occur or myopathy is diagnosed or suspected. Taking other medicines Caution should be exercised when administering Amlodipine as with any other peripheral vasodilator particularly in patients with severe aortic stenosis. Pregnancy and breast-feeding Safety in pregnancy has not been established. 3. How to take Amdova? Amlodipine: The usual initial antihypertensive oral dose is 5 mg once daily with a maximum dose of 10 mg once daily. Elderly individuals or patients with hepatic insufficiency may be started on 2.5 mg once daily dose and this dose may be used when adding Amlodipine to other antihypertensive therapy. Dosage should be adjusted according to each patient's need. The recommended dose for chronic stable or vasospastic angina is 5-10 mg, with the lower dose suggested in the elderly and in patients with hepatic insufficiency. Atorvastatin: Adults: The patient should be placed on a standard cholesterol-lowering diet before receiving Atorvastatin and should continue on this diet during treatment with Atorvastatin Hypercholesterolemia (Heterozygous Familial and Nonfamilial) and Mixed Dyslipidemia (Fredrickson Types IIa and IIb): The recommended starting dose of Atorvastatin is 10 mg daily. The dosage range is 10 to 80 mg once daily. Atorvastatin can be administered as a single dose at any time of the day with or without food. Homozygous Familial Hypercholesterolemia: The dosage of Atorvastatin in patients with homozygous FH is 10 to 80 mg daily. Patients with renal insufficiency: Renal disease has no influence on the plasma concentrations or lipid effects of Atorvastatin; thus no adjustment of dose is required. Hemodialysis is not expected to significantly enhance the clearance of Atorvastatin since the drug is extensively bound to plasma proteins. Patients with hepatic dysfunction: In patients with moderate to severe hepatic dysfunction, the therapeutic response to Atorvastatin is unaffected but exposure to the drug is greatly increased. If you take more Amdova than you should In humans, experience with intentional overdosage of Amlodipine & Atorvastatin is limited. If massive overdosage occurs, act..

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Amikin 100 Inj

Amikin 100 Inj

Amikin 100 InjPresentationAmikin 100 IM/IV Injection: Each 2ml ampoule contains 100 mg Amikacin as Amikacin Sulfate USP.DescriptionAmikacin Sulfate is a semi-synthetic aminoglycoside antibiotic. Amikacin is active in vitro against Pseudomonas species, Escherichia coli, Proteus species, Providencia species, Klebsiella-Enterobacter species, Acinetobacter species, and Citrobacter freundii. When strains of the above organisms are found to be resistant to other aminoglycosides, including Gentamicin, TobrAmykin and KanAmykin, many are susceptible to Amikacin. Amikacin sulfate is active in vitro against penicillinase and nonpenicillinase-producing Staphylococcus species including methicillin-resistant strains.IndicationsAmikacin is indicated in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. It is effective in bacterial septicemia (including neonatal sepsis); in serious infections of the respiratory tract, bones and joints, central nervous system (including meningitis) and skin and soft tissue; intra abdominal infections (including peritonitis); and in bums and post operative infections (including post-vascular surgery). Amikacin is also effective in serious complicated and recurrent urinary tract infections due to susceptible Gram-negative organisms. It may be considered as initial therapy in suspected Gram-negative infections and therapy may be instituted before obtaining the results of susceptibility. Amikacin is also effective in infections caused by Gentamycln and/or TobrAmykin resistant strains of Gram-negative organisms. Amikacin has also been shown to be effective in Staphylococcal infection and may be considered as initial therapy under certain condition in the treatment of known suspected Staphylococcal disease such as, severe infections where the causative organism may either a Gram-negative bacterium or Staphylococcus infection due to susceptible strains of Staphylococcal I Gram-negative infections. In certain severe infections such as neonatal sepsis, concomitant therapy with a penicillin type drug may be indicated because of the possibility of infections due to Gram positive organism such as streptococci or pneumococci.Dosage & AdministrationAdults and children: 15mg/kg/day in two equally- divided doses (equivalent to 500 mg bid in adults). Use of the 100 mg/2 ml strength is recommended for children for the accurate measurement of the appropriate dose.Neonates and premature children: An initial loading dose of 10 mg/kg followed by 15 mg/kg/day in two equally divided doses.Elderly: Doses should be adjusted under impaired renal function in elderly.Life-threatening infections and/or those caused by pseudomonas: The adult dose may be increased to 500 mg every eight hours but should neither exceed 1.5 gm/day nor be administered for a period longer than 10 days. A maximum total adult dose of 15 gm should not be exceeded.Urinary tract infections (Other than pseudomonal infections): 7.5 mg/kg/day in two equally divided doses (equivalent to 250 mg bid in adults).Impaired renal function: In patient with impaired renal function the daily dose should be reduced and/or the intervals between doses increased to avoid accumulation of the drug. Simple doses schedule for renal impairment is given below:Renal function Dosage scheduleMild impairment 500 mg every 18 hoursModerate impairment 500 mg every 24 hoursSevere impairment 250 mg every 24 hours.Administration:Intramuscular or intravenous administration: For most infections the intramuscular route is preferred, but in life threatening infections, or in patients in whom intramuscular injection route is not feasible the intravenous route may be used.Intraperitoneal use: Amikacin may be used as an irrigant after recovery from anesthesia in concentration of 0.25%.Other routes of administration: Amikacin in concentration of 0.25% may be used satisfactorily as an irrigating solution in abscess cavities, the pleural space, the peritoneum and the cerebral ventricles.Side EffectsWhen the recommended precautions and dosages are followed the incidence of toxic reactous, such as tinnitus vertigo, and partial reversible or irreversible deafness, skin rash, drug fever, headache, paraesthesia, nausea and vomiting is low. Urinary signs of renal irritation, azotaemia and oliguria have been reported.PrecautionsSince Amikacin is present in high concentrations in the renal excretory system, patients should be well hydrated to minimize chemical irritation of the renal tubules. If azotemia increases, treatment should be stopped. Monitoring of renal function during treatment with aminoglycosides is particularly important.Use in Pregnancy & LactationThe safety of Amikacin in pregnancy has not yet been established.Drug InteractionNo information regarding drug interaction of Amikacin is available.Over DoseIn the event of overdose or toxic reaction, peritoneal dialysis or hemodialysis will aid in the removal of Amikacin from the blo..

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Amikin 500 Inj

Amikin 500 Inj

Amikin 500 InjPresentationAmikin 500 IM/IV Injection: Each 2ml ampoule contains 500 mg Amikacin as Amikacin Sulfate USP.DescriptionAmikacin Sulfate is a semi-synthetic aminoglycoside antibiotic. Amikacin is active in vitro against Pseudomonas species, Escherichia coli, Proteus species, Providencia species, Klebsiella-Enterobacter species, Acinetobacter species, and Citrobacter freundii. When strains of the above organisms are found to be resistant to other aminoglycosides, including Gentamicin, TobrAmykin and KanAmykin, many are susceptible to Amikacin. Amikacin sulfate is active in vitro against penicillinase and nonpenicillinase-producing Staphylococcus species including methicillin-resistant strains.IndicationsAmikacin is indicated in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. It is effective in bacterial septicemia (including neonatal sepsis); in serious infections of the respiratory tract, bones and joints, central nervous system (including meningitis) and skin and soft tissue; intra abdominal infections (including peritonitis); and in bums and post operative infections (including post-vascular surgery). Amikacin is also effective in serious complicated and recurrent urinary tract infections due to susceptible Gram-negative organisms. It may be considered as initial therapy in suspected Gram-negative infections and therapy may be instituted before obtaining the results of susceptibility. Amikacin is also effective in infections caused by Gentamycln and/or TobrAmykin resistant strains of Gram-negative organisms. Amikacin has also been shown to be effective in Staphylococcal infection and may be considered as initial therapy under certain condition in the treatment of known suspected Staphylococcal disease such as, severe infections where the causative organism may either a Gram-negative bacterium or Staphylococcus infection due to susceptible strains of Staphylococcal I Gram-negative infections. In certain severe infections such as neonatal sepsis, concomitant therapy with a penicillin type drug may be indicated because of the possibility of infections due to Gram positive organism such as streptococci or pneumococci.Dosage & AdministrationAdults and children: 15mg/kg/day in two equally- divided doses (equivalent to 500 mg bid in adults). Use of the 100 mg/2 ml strength is recommended for children for the accurate measurement of the appropriate dose.Neonates and premature children: An initial loading dose of 10 mg/kg followed by 15 mg/kg/day in two equally divided doses.Elderly: Doses should be adjusted under impaired renal function in elderly.Life-threatening infections and/or those caused by pseudomonas: The adult dose may be increased to 500 mg every eight hours but should neither exceed 1.5 gm/day nor be administered for a period longer than 10 days. A maximum total adult dose of 15 gm should not be exceeded.Urinary tract infections (Other than pseudomonal infections): 7.5 mg/kg/day in two equally divided doses (equivalent to 250 mg bid in adults).Impaired renal function: In patient with impaired renal function the daily dose should be reduced and/or the intervals between doses increased to avoid accumulation of the drug. Simple doses schedule for renal impairment is given below:Renal function Dosage scheduleMild impairment 500 mg every 18 hoursModerate impairment 500 mg every 24 hoursSevere impairment 250 mg every 24 hours.Administration:Intramuscular or intravenous administration: For most infections the intramuscular route is preferred, but in life threatening infections, or in patients in whom intramuscular injection route is not feasible the intravenous route may be used.Intraperitoneal use: Amikacin may be used as an irrigant after recovery from anesthesia in concentration of 0.25%.Other routes of administration: Amikacin in concentration of 0.25% may be used satisfactorily as an irrigating solution in abscess cavities, the pleural space, the peritoneum and the cerebral ventricles.Side EffectsWhen the recommended precautions and dosages are followed the incidence of toxic reactous, such as tinnitus vertigo, and partial reversible or irreversible deafness, skin rash, drug fever, headache, paraesthesia, nausea and vomiting is low. Urinary signs of renal irritation, azotaemia and oliguria have been reported.PrecautionsSince Amikacin is present in high concentrations in the renal excretory system, patients should be well hydrated to minimize chemical irritation of the renal tubules. If azotemia increases, treatment should be stopped. Monitoring of renal function during treatment with aminoglycosides is particularly important.Use in Pregnancy & LactationThe safety of Amikacin in pregnancy has not yet been established.Drug InteractionNo information regarding drug interaction of Amikacin is available.Over DoseIn the event of overdose or toxic reaction, peritoneal dialysis or hemodialysis will aid in the removal of Amikacin from the blo..

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Amilin 10mg tab

Amilin 10mg tab

Amilin 10mg tab..

Tk.0.85/=

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Amilin 25mg tab

Amilin 25mg tab

Amilin 25mg tab..

Tk.1.75/=

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Amit 10 Tab

Amit 10 Tab

Amit 10 Tab..

Tk.0.85/=

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Amit 25 Tab

Amit 25 Tab

Amit 25 Tab..

Tk.1.76/=

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Amitor 5/10

Amitor 5/10

Amitor 5/10..

Tk.11.93/=

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Amlobet tablet

Amlobet tablet

Amlobet tablet..

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Amlopin 10 Tablet

Amlopin 10 Tablet

Amlopin 10 Tablet..

Tk.7.02/=

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Amlopin 5mg Tab

Amlopin 5mg Tab

Amlopin 5mg Tab..

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Amlosartan 10/160 Tab

Amlosartan 10/160 Tab

Indications Amlodipine and Valsartan combination is indicated for the treatment of hypertension. This fixed combination drug is not indicated for the initial therapy of hypertension Therapeutic Class Combined antihypertensive preparations Pharmacology Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II by selectively blocking the binding of Angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for Angiotensin II synthesis. Amlodipine and Valsartan have been shown to be effective in lowering blood pressure. Both Amlodipine and Valsartan lower blood pressure by reducing peripheral resistance, but calcium influx blockade and reduction of Angiotensin II vasoconstriction are complementary mechanisms. Dosage & Administration Amlodipine is an effective treatment of hypertension in once daily doses of 2.5 mg-10 mg while Valsartan is effective in doses of 80 mg-320 mg. In clinical trials with Amlodipine and Valsartan combination using Amlodipine doses of 5 mg-10 mg and Valsartan doses of 160 mg-320 mg, the antihypertensive effects increased with increasing doses. Interaction No drug interaction studies have been conducted with Amlodipine and Valsartan combination and other drugs, although studies have been conducted with the individual Amlodipine and Valsartan components Contraindications Amlodipine and Valsartan combination is contraindicated in patients who are hypersensitive to any compounds of this product. Side Effects The most common side effects include peripheral edema, vertigo, nasopharyngitis, upper respiratory tract infection and dizziness. Pregnancy & Lactation Pregnancy: Amlodipine and Valsartan combination should not be used in 2nd and 3rd trimester because it can cause fetal death .Nursing Mothers: It is not known whether Valsartan and Amlodipine are excreted in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother. Precautions Amlosartan should be used with caution because there is a risk for fetal or neonatal morbidity, hypotension, myocardial infarction or increased angina.Dose should be titrated slowly in patients with impaired hepatic or severely impaired renal function. In general, calcium channel blockers should be used with caution in patients with heart failure. Overdose Effects Limited data of human overdosage have been reported. Use in Special Population Pediatric use: The safety and effectiveness has not been established in pediatric patients.Geriatric use: No differences in overall incidence of adverse events were observed in elderly.Renal impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment. Titrate slowly in patients with severe renal impairment. Hepatic impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency. Titrate slowly in patients with hepatic impairment. Storage Conditions Store in a cool dry place protected from light. Keep out of reach of children. ..

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Amlosartan 5/160 Tab

Amlosartan 5/160 Tab

Indications Amlodipine and Valsartan combination is indicated for the treatment of hypertension. This fixed combination drug is not indicated for the initial therapy of hypertension Therapeutic Class Combined antihypertensive preparations Pharmacology Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II by selectively blocking the binding of Angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for Angiotensin II synthesis. Amlodipine and Valsartan have been shown to be effective in lowering blood pressure. Both Amlodipine and Valsartan lower blood pressure by reducing peripheral resistance, but calcium influx blockade and reduction of Angiotensin II vasoconstriction are complementary mechanisms. Dosage & Administration Amlodipine is an effective treatment of hypertension in once daily doses of 2.5 mg-10 mg while Valsartan is effective in doses of 80 mg-320 mg. In clinical trials with Amlodipine and Valsartan combination using Amlodipine doses of 5 mg-10 mg and Valsartan doses of 160 mg-320 mg, the antihypertensive effects increased with increasing doses. Interaction No drug interaction studies have been conducted with Amlodipine and Valsartan combination and other drugs, although studies have been conducted with the individual Amlodipine and Valsartan components Contraindications Amlodipine and Valsartan combination is contraindicated in patients who are hypersensitive to any compounds of this product. Side Effects The most common side effects include peripheral edema, vertigo, nasopharyngitis, upper respiratory tract infection and dizziness. Pregnancy & Lactation Pregnancy: Amlodipine and Valsartan combination should not be used in 2nd and 3rd trimester because it can cause fetal death .Nursing Mothers: It is not known whether Valsartan and Amlodipine are excreted in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother. Precautions Amlosartan should be used with caution because there is a risk for fetal or neonatal morbidity, hypotension, myocardial infarction or increased angina.Dose should be titrated slowly in patients with impaired hepatic or severely impaired renal function. In general, calcium channel blockers should be used with caution in patients with heart failure. Overdose Effects Limited data of human overdosage have been reported. Use in Special Population Pediatric use: The safety and effectiveness has not been established in pediatric patients.Geriatric use: No differences in overall incidence of adverse events were observed in elderly.Renal impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment. Titrate slowly in patients with severe renal impairment. Hepatic impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency. Titrate slowly in patients with hepatic impairment. Storage Conditions Store in a cool dry place protected from light. Keep out of reach of children. ..

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Amlosartan 5/80 Tab

Amlosartan 5/80 Tab

Amlosartan 5/80 TabPresentationAmlosartan 5/80: Each tablet contains Amlodipine Besilate BP equivalent to Amlodipine 5 mg & Valsartan USP 80 mg.DescriptionAmlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Amlodipine has a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure.Valsartan is an oral medication that belongs to a class of drugs called angiotensin receptor blockers (ARBs). It is orally active and specific angiotensin II antagonist acting on the AT1 subtype. Angiotensin's attachment to the receptors causes the blood vessels to narrow (vasoconstrict) which leads to an increase in blood pressure (hypertension). Valsartan blocks the angiotensin II receptor. By blocking the action of angiotensin, Valsartan dilates blood vessels and reduces blood pressure without affecting pulse rate. Valsartan has much greater affinity (about 20,000-fold) for the AT1 receptor than for the AT2 receptor. It does not bind or block other hormone receptors or ion channels known to be important in cardiovascular regulation.IndicationsAmlosartan is indicated for the treatment of hypertension. This combination drug is not indicated for the initial therapy of hypertension.Dosage & AdministrationAmlodipine is an effective treatment of hypertension in once daily doses of 2.5 mg to 10 mg while Valsartan is effective in doses of 80 mg to 320 mg. The majority of the antihypertensive effect is attained within 2 weeks after initiation of therapy or a change in dose. The dosage can be increased after 1 to 2 weeks of therapy to a maximum of one 10/320 mg tablet once daily as needed to control blood pressure.Amlosartan may be administered with or without food. Amlosartan may be administered with other antihypertensive agents. A patient whose blood pressure is not adequately controlled with Amlodipine alone or with Valsartan alone may be switched to their combination therapy.Elderly patients: Because of decreased clearance of Amlodipine, therapy should usually be initiated at 2.5 mg.Renal impairment: No initial dosage adjustment is required for patients with mild or moderate renal impairment. Titrate slowly in patients with severe renal impairment.Hepatic impairment: No initial dosage adjustment is required for patients with mild or moderate liver insufficiency. Titrate slowly in patients with hepatic impairment.Side EffectsThe most common side effects include peripheral edema, vertigo, nasopharyngitis, upper respiratory tract infection and dizziness.PrecautionsAmlosartan should be used with caution because there is a risk for-fetal or neonatal morbidityhypotensionmyocardial infarction or increased anginaDose should be titrated slowly in patients with impaired hepatic or severely impaired renal function. In general, calcium channel blockers should be used with caution in patients with heart failure.Use in Pregnancy & LactationPregnancy: Amlodipine and Valsartan combination should not be used in 2nd and 3rd trimester because it can cause fetal death .Nursing Mothers: It is not known whether Valsartan and Amlodipine are excreted in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.Over DoseLimited data of human overdosage have been reported.Commercial PackAmlosartan 5/80: Each box contains 3 alu-alu blister strips of 10 tablets...

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Amlosun 5 tablet

Amlosun 5 tablet

Amlosun 5 tablet..

Tk.5.02/=

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