Adarbi 40 mg Tablet, 1 Strip
Adarbi 40 mg Tablet, 1 StripDescription:Adarbi (Azilsartan Medoxomil), a prodrug, is hydrolyzed to Azilsartan in the gastrointestinal tract during absorption. Azilsartan is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan blocks the vasoconstrictor and aldosterone secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland.IndicationAdarbi (Azilsartan Medoxomil) is indicated for the treatment of hypertension to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily stroke and myocardial infarction. Adarbi (Azilsartan Medoxomil) may be used either alone or in combination with other antihypertensive agents.Dosage & AdministrationThe recommended dose in adults is 80 mg taken orally once daily. Consider a Starting dose of 40 mg for patients who are treated with high doses of diuretics. If blood pressure is not controlled with Adarbi alone, additional blood pressure reduction can be ahieved by taking Edarbi with other antihypertensive agents.ContraindicationIt is contraindicated to co-administer Aliskiren with Azilsartan in patients with Diabetes.PrecautionUse of Azilsartan Medoxomil during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. In patients who are intravascularly volume-depleted (e.g., those treated with high-dose diuretics), symptomatic hypotension may occur. Changes in renal function including renal failure has been reported in renal impaired patient.Side EffectsThe most common adverse reaction in adults is diarrhea. The other side effects are nausea, asthenia, fatigue, muscle spasm, dizziness and cough.Drug InteractionNo drug interactions have been observed in studies of Azilsartan Medoxomil or Azilsartan given with amlodipine, antacids, chlorthalidone, digoxin, fluconazole, glyburide, ketoconazole, metformin, pioglitazone and warfarin. The antihypertensive effect of Azilsartan may be attenuated by the non-steroidal anti-inflammatory drugs including selective COX-2 inhibitors. Dual blockade of the RAS with angiotensin receptor blockers, ACE inhibitors or aliskiren is associated with increased risks of hypotension, hyperkalemia and changes in renal function.Storage Conditionkeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.120.00/=
Altrip 6.25 mg Tablet, 1 strip
Altrip 6.25 mg Tablet, 1 stripDescription:Almotriptan is a selective and potent serotonin (5-HT1B/1D) agonist. Almotriptan binds to specific serotonin receptors on meningeal arteries inhibiting the release of vasoactive peptides and causing constriction of the arteries. It has a limited effect on arteries supplying blood to the brain and little effect on cardiac and pulmonary vessels.ndicationAlmotriptan is prescribed to treat the acute headache phase of migraine attacks with or without aura. Almotriptan is the only oral triptan approved in the USA for the treatment of migraine in adolescent from 12 to 17 years of age.Dosage & AdministrationAcute Treatment of Migraine Attacks: The recommended dose of Altrip in adults and adolescents age 12 to 17 years is 6.25 mg to 12.5 mg, with the 12.5 mg dose tending to be a more effective dose in adults. If the headache is relieved after the initial Altrip (almotriptan malate) dose but returns, the dose may be repeated after 2 hours. The maximum daily dose should not exceed 25 mg. The safety of treating an average of more than four migraines in a 30-day period has not been established.Hepatic Impairment:The recommended starting dose of almotriptan malate in patients with hepatic impairment is 6.25 mg. The maximum daily dose should not exceed 12.5 mg over a 24-hour periodRenal Impairment:The recommended starting dose of almotriptan malate in patients with severe renal impairment is 6.25 mg. The maximum daily dose should not exceed 12.5 mg over a 24-hour periodContraindicationAs with other 5-HT1B/1D receptor agonists, almotriptan should not be used in patients with a history, symptoms or signs of ischaemic heart disease (myocardial infarction, angina pectoris, documented silent ischaemia, Prinzmetals angina) or severe hypertension and uncontrolled mild or moderate hypertension. Concomitant administration with ergotamine, ergotamine derivatives (including methysergide) and other 5-HT1B/1D agonists is contraindicated.PrecautionHypersensitivity to the active substance or to any of the excipients. Patients with severe hepatic impairment, with a previous cerebrovascular accident (CVA) or transient ischaemic attack (TIA) Peripheral vascular diseaseSide EffectsSerious cardiac reactions, including myocardial infarction, have occurred following the use of almotriptan malate Tablets. These reactions are extremely rare and most have been reported in patients with risk factors predictive of CAD (Coronary Artery Disease).Drug InteractionThese drugs have been reported to cause prolonged vasospastic reactions. Cases of life-threatening serotonin syndrome have been reported during combined use of triptans and selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs).OverdoseNo case of overdose has been reported. The most frequently reported adverse event in patients receiving 150 mg (the highest dose administered to patients) was somnolence.Pregnancy & LactationPregnancy Category C. There is no data regarding excretion of almotriptan in human milk.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.250.80/=
Anxionil 3 mg Tablet, 1 strip
Anxionil 3 mg Tablet, 1 stripDescription:Anxionil is a preparation of Bromazepam. Bromazepam is a powerful psychotropic agent. In lower dosage, it selectively reduces tension and anxiety. In higher dosage, it shows sedative and muscle-relaxant properties.IndicationEmotional disturbances, i.e. acute tension and anxiety states. Difficulties in interpersonal contact. Agitation, insomnia, anxious and agitated depressive reactions.Functional disturbances in the cardiovascular and respiratory systems, i.e. pseudoangina pectoris, pericardial anxiety, tachycardia, emotiogenic hypertension, dyspnea and hyperventilation.Disturbances in the gastrointestinal tract, i.e. irritable bowel syndrome, epigastric pain, spasm, bloating diarrhea etc.Disturbances in the urinary tract, i.e. frequency, irritable bladder and dysmenorrhea. Psychosomatic disorder, i.e. psychogenic headache, asthma, gastric and duodenal ulcer. It is also indicated in emotional reactions to chronic organic disease.Dosage & AdministrationStandard dosage : Average dosage for outpatient therapy is 1.5-3 mg up to three times daily. Treatment of outpatients should begin with low doses, gradually increasing to the optimum level. In severe cases, especially in hospital, 6 -12 mg 2 or 3 times daily. The overall treatment generally should not be more than 8-12 weeks. In certain cases extension beyond the maximum treatment period may be necessary; if so, it should be taken with re-evaluation of the patients status with special expertise.Elderly and debilitated patients : Elderly patients and those with impaired hepatic functions require lower doses.Children : Bromazepam is usually not indicated in children, but if the physician feels bromazepam treatment is appropriate, then the dose should be adjusted to their low bodyweight (about 0.1-0.3 mg/kg bodyweight)ContraindicationBromazepam is contraindicated in patients with known hypersensitivity to bromazepam, severe respiratory insufficiency, severe hepatic insufficiency or sleep apnea syndromPrecautionThe use of benzodiazepines and benzodiazepine like agents may lead to the development of physical and psychological dependence upon these products. This dependence depends on the dose and duration of treatment; it is also greater in predisposed patients with a history of alcohol. Once physical dependence has developed, termination of the treatment will be accompanied by withdrawal symptoms. These may consist of headache, muscle pain, extreme anxiety, tension, confusion and irritability. Since the risk of withdrawal phenomena and rebound phenomena is greater after abrupt discontinuation of the treatment, it is recommended that the dosage be decreased gradually. Bromazepam is not recommended for the primary treatment of sleeplessness caused by psychotic illness. Caution should be exercised while driving cars or using machineries.Side EffectsCommon side-effects include fatigue, drowsiness, muscle weakness, numbed muscle, reduced alertness, confusion, headache, ataxia etc. These phenomena occur predominantly at the start of therapy and usually disappear with prolonged administration. Anterograde amnesia may occur using therapeutic dosDrug InteractionIf bromazepam is combined with other centrally active drugs, its sedative effects may be enhanced. These drugs are antidepressants, hypnotics, narcotics, antipsychotics, sedatives, antiepileptic drugs, sedative antihistamines and anesthetics. Co-administration of cimetidine may prolong the eliminiation half-life of bromazepam. Concomitant intake of bromazepam with alcohol should be avoided, because the sedative effect of bromazepam may be intensified by alcoPregnancy & LactationThe safety of bromazepam during pregnancy has not been established. As bromazepam is excreted in breast milk, use should be avoided during lactatioStorage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.50.20/=
Arcet 10 mg Tablet, 1 strip
Arcet 10 mg Tablet, 1 stripDescription:Arcet (Cetirizine Dihydrochloride) is a potent H1 receptor antagonist without any significant anticholinergic and antiserotonic effects. At pharmacologically active dose levels, it has almost no drowsiness effect and does not cause behavioural changes. It inhibits the histamine mediated early phase of the allergic reaction and also reduces the migration of inflammatory cells and the release of mediators associated with the late phase of the allergic reaction.IndicationIt is indicated for the relief of symptoms associated with seasonal & perennial allergic rhinitis. It is also indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria and allergen induced asthma.Dosage & AdministrationAdults and Children 6 years and older : 1 tablet or 2 teaspoonfuls daily (or 1 teaspoonful twice daily).Children 2-6 years : 1 teaspoonful once daily or 1/2 teaspoonful twice daily.Children 6 months - <2 years : 1/2 teaspoonful once daily. The dose in children 12-23 months of age can be increased to a maximum dose as 1/2 teaspoonful every 12 hours.ContraindicationIt is contraindicated in patients with a history of hypersensitivity to Cetirizine or hydroxyzine.PrecautionCaution should be exercised when driving a car or operating a heavy machinerySide EffectsThe most common side effects that occurred more frequently on Cetirizine is somnolence.Drug InteractionNo clinically significant drug interactions have been found with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole or Erythromycin and with other drugs.Pregnancy & LactationUS FDA Pregnancy Category of Cetirizine Dihydrochloride is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Cetirizine Dihydrochloride has been shown to be excreted in human milk. So, caution should be exercised when Cetirizine Dihydrochloride is administered to a nursing woman.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.20.10/=
Azaltic 35ml Susp.
Azaltic 35ml Susp.Description:Azaltic (Azithromycin) is an azalide antibiotic, subclass of the macrolide antibiotic, active against both Gram-positive and Gram-negative organisms. Azithromycin acts by binding to the 50S ribosomal subunit of susceptible organisms, thus interferes with the microbial protein synthesis.ndicationAzaltic (Azithromycin) is indicated for infections caused by susceptible organisms in lower respiratory tract infections including bronchitis and pneumonia, skin and soft tissue infections, otitis media and in upper respiratory tract infections including sinusitis, pharyngitis and tonsillitis. It is also indicated in the treatment of uncomplicated genital infections due to Chlamydia trachomatis & typhoid fever.Dosage & AdministrationAdult : 500 mg once daily orally for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days. For sexually transmitted diseases caused by Chlamydia trachomatis in adults, the dose is 1 gm given as a single dose or 500 mg once on day 1, followed by 250 mg once daily for next 2 days may also be given.Children : 10 mg/kg body weight once daily for 3 days for child over 6 months or 200 mg (1 teaspoonful) for 3 days if body weight is 15-25 kg; 300 mg (1½ teaspoonfuls) for 3 days if body weight is 26-35 kg; 400 mg (2 teaspoonfuls) for 3 days if body weight is 36-45 kg. In typhoid fever, 500 mg once daily for 7-10 days is given. Azaltic (Azithromycin) should be taken at least 1 hour before or 2 hours after meal.ContraindicationAzithromycin is contraindicated in patients with known hypersensitivity to Azithromycin or any other macrolide antibiotics. Azithromycin is contraindicated in patients with hepatic diseases.PrecautionAs with any antibiotic, observation for signs of superinfection with non-susceptible organisms, including fungi, is recommended. Precaution should be taken in patients with more severe renal impairment.Side EffectsAzithromycin is well tolerated with a low incidence of side effects. The side effects include nausea, vomiting, abdominal discomfort (pain/cramps), flatulence, diarrhoea, headache, dizziness, and skin rashes which are reversible upon discontinuation of therapy.Drug InteractionAzithromycin absorption is reduced in presence of food and antacid. In patients receiving ergot alkaloids Azithromycin should be avoided because of the possibility of ergotism resulting from interaction of Azithromycin with the cytochrome P-450 system. Macrolides have been known to increase the plasma concentration of digoxin and cyclosporin. There have been no drug interactions between Azithromycin and Warfarin, Theophylline, Carbamazepine, Methylprednisolone or Cimetidine.Pregnancy & LactationPregnancy Category of Azithromycin is B. Animal reproduction studies have demonstrated that Azithromycin has no evidence of harm to the fetus. There are no adequate and well controlled studies in pregnant women. Since animal reproduction studies are not always predictive of human response, Azithromycin should be used during pregnancy only if adequate alternatives are not available. It is not known whether Azithromycin is secreted in breast milk. So, caution should be exercised when Azithromycin is administered to nursing women.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Azaltic 500 mg tab
Azaltic 500 mg tabDescription:Azaltic (Azithromycin) is an azalide antibiotic, subclass of the macrolide antibiotic, active against both Gram-positive and Gram-negative organisms. Azithromycin acts by binding to the 50S ribosomal subunit of susceptible organisms, thus interferes with the microbial protein synthesis.ndicationAzaltic (Azithromycin) is indicated for infections caused by susceptible organisms in lower respiratory tract infections including bronchitis and pneumonia, skin and soft tissue infections, otitis media and in upper respiratory tract infections including sinusitis, pharyngitis and tonsillitis. It is also indicated in the treatment of uncomplicated genital infections due to Chlamydia trachomatis & typhoid fever.Dosage & AdministrationAdult : 500 mg once daily orally for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days. For sexually transmitted diseases caused by Chlamydia trachomatis in adults, the dose is 1 gm given as a single dose or 500 mg once on day 1, followed by 250 mg once daily for next 2 days may also be given.Children : 10 mg/kg body weight once daily for 3 days for child over 6 months or 200 mg (1 teaspoonful) for 3 days if body weight is 15-25 kg; 300 mg (1½ teaspoonfuls) for 3 days if body weight is 26-35 kg; 400 mg (2 teaspoonfuls) for 3 days if body weight is 36-45 kg. In typhoid fever, 500 mg once daily for 7-10 days is given. Azaltic (Azithromycin) should be taken at least 1 hour before or 2 hours after meal.ContraindicationAzithromycin is contraindicated in patients with known hypersensitivity to Azithromycin or any other macrolide antibiotics. Azithromycin is contraindicated in patients with hepatic diseases.PrecautionAs with any antibiotic, observation for signs of superinfection with non-susceptible organisms, including fungi, is recommended. Precaution should be taken in patients with more severe renal impairment.Side EffectsAzithromycin is well tolerated with a low incidence of side effects. The side effects include nausea, vomiting, abdominal discomfort (pain/cramps), flatulence, diarrhoea, headache, dizziness, and skin rashes which are reversible upon discontinuation of therapy.Drug InteractionAzithromycin absorption is reduced in presence of food and antacid. In patients receiving ergot alkaloids Azithromycin should be avoided because of the possibility of ergotism resulting from interaction of Azithromycin with the cytochrome P-450 system. Macrolides have been known to increase the plasma concentration of digoxin and cyclosporin. There have been no drug interactions between Azithromycin and Warfarin, Theophylline, Carbamazepine, Methylprednisolone or Cimetidine.Pregnancy & LactationPregnancy Category of Azithromycin is B. Animal reproduction studies have demonstrated that Azithromycin has no evidence of harm to the fetus. There are no adequate and well controlled studies in pregnant women. Since animal reproduction studies are not always predictive of human response, Azithromycin should be used during pregnancy only if adequate alternatives are not available. It is not known whether Azithromycin is secreted in breast milk. So, caution should be exercised when Azithromycin is administered to nursing women.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.35.00/=
Cefracef 500 Capsule
Cefracef 500Description:Cefracef (Cefradine) is a cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia, nose, ear, throat, skin and urinary tract infections. It is acid stable and rapidly absorbed after oral administration. The presence of food in the gastrointestinal tract delays absorption but does not affect the total amount of Cefradine absorbed. Over 90% of this drug is excreted as unchanged in the urine within six hours.IndicationCefracef (Cefradine) is indicated in the treatment of the following infections caused by susceptible strains of the designated microorganisms: Respiratory tract infections (e.g. tonsillitis, pharyngitis and lobar pneumonia) caused by group A beta-hemolytic Streptococci and Streptococcus pneumoniae. Skin and skin structure infections caused by Staphylococci (penicillin-susceptible and penicillin-resistant) and beta-hemolytic Streptococci. Urinary tract infections including prostatitis caused by E. coli, Proteus mirabilis, Klebsiella species, and Enterococci. It is also used in otitis media caused by group A beta-hemolytic Streptococci, Streptococcus pneumoniae, Haemophilus influenzae and Staphylococci.Dosage & AdministrationAdults : For respiratory tract infections (other than lobar pneumonia) and skin and skin structure infections, the usual dose is 250 mg every 6 hours or 500 mg every 12 hours. For lobar pneumonia, the usual dose is 500 mg every 6 hours or 1 g every 12 hours.For uncomplicated urinary tract infections, the usual dose is 500 mg every 12 hours. In more serious urinary tract infections, including prostatitis, 500 mg every 6 hours or 1 g every 12 hours may be administered.Children : The usual dose in children over nine months of age is 25 to 50 mg/kg/day administered in equally divided doses every 6 or 12 hours. For otitis media due to H. influenzae, doses are from 75 to 100 mg/kg/day administered in equally divided doses every 6 or 12 hours, but should not exceed 4 g per day.ContraindicationIt is contraindicated in hypersensitivity to Cefradine or other cephalosporins.PrecautionCare is necessary with known history of allergy. Renal and hematological status should be monitored especially during prolonged and high doses therapy.Side EffectsAs with other cephalosporins, side effects are limited essentially to gastrointestinal disturbances and on occasion, to hypersensitivity phenomena, eosinophilia.Drug InteractionThe concomitant use of nephrotoxic drugs such as aminoglycosides with Cefradine may increase the risk of kidney damage. Diuretics (e.g. frusemide, ethacrynic acid) and probenecid enhanced the possibility of renal toxicity.Pregnancy & LactationUS FDA Pregnancy Category of Cefradine is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Cefradine have been shown to be excreted in human milk. So, caution should be exercised when Cefradine is administered to a nursing woman.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.12.59/=
Cialix 10 mg Tab, 1 Box
Cialix 10 mg Tab, 1 BoxDescription:Ciali (Tadalafil) is a selective phosphodiesterase type 5 (PDE5) inhibitor. Inhibition of PDE5 increases cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum, causing penile erection. PDE5 also is present in smooth muscles of the prostate and bladder wall. Inhibiting PDE5 increases cGMP concentrations leading to relaxation of smooth muscle in the prostate and bladder. Smooth muscle relaxation may improve blood flow to the urinary tract and widen the opening of the bladder neck, resulting in improved voiding.Indication* Erectile dysfunction (ED)* Benign prostatic hyperplasia (BPH)* Both Erectile Dysfunction and signs and symptoms of benign prostatic hyperplasia.Dosage & AdministrationErectile Dysfunction: For most patients the recommended starting dose is 10 mg. The dose may be increased to 20 mg or decreased to 5 mg based on requirement. The maximum dosing frequency is once daily.Ciali is effective for up to 36 hours.Benign prostatic hyperplasia : The recommended dose is 5 mg taken at the same time every day.Combined Erectile Dysfunction and Benign prostatic hyperplasia: The recommended dose is 5 mg at the same time every day.ContraindicationUse of nitrates (for example, nitroglycerine, isosorbide): Ciali may increase hypotensive effects of nitrates.Hypersensitivity reactions to tadalafil.PrecautionAngina, nitrates, alpha blockers, renal impairment, hepatic impairment, alcohol, CYP3A4 inhibitors (for example, ritonavir, ketoconazole, itraconazole), other PDE5 inhibitors, bleeding - precaution should be taken in all these conditions.Side EffectsHeadache, Dyspepsia, Back pain, Myalgia, Nasal pharyngitis, Nasal congestion are common side effects. Change in Color Vision, NAION (Sudden vision loss), Hearing loss, Stevens-Johnson Syndrome, Exfoliative dermatitis, Angina, Stroke, Myocardial infarction, Severe hypotension, Tachycardia may also occur rarely.Drug InteractionMay interact with Nitrates for example, isosorbide, nitroglycerin, Alpha adrenergic blockers, Antihypertensives, Alcohol, Antacids (magnesuim hydroxide/aluminum hydroxide), Ketoconazole, ritonavir, erythromycin, itraconazole, grapefruit juice, other HIV protease inhibitors, Rifampin, carbamazepine, phenytoin & Phenobarbital.Pregnancy & LactationTadalafil has been assigned to pregnancy category B by the USFDA. Tadalafil is only recommended for use during pregnancy when benefit outweighs risk. There are no data on the excretion of tadalafil in human milk. Caution should be used when administering tadalafil to nursing women.Storage ConditionKeep in a dry place away from light and heat. Keep out of reach of children...
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Ex Tax: Tk.140.44/=
Danafil 100 mg Tablet
Danafil 100 mg TabletDescription:Danafil (Sildenafil Citrate) is a selective inhibitor of cyclic Guanosine Monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) for treatment of erectile dysfunction. Danafil (Sildenafil Citrate) enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum that results in smooth muscle relaxation and inflow of blood to the corpus cavernosum.IndicationDanafil is indicated for the treatment of erectile dysfunction.Dosage & AdministrationThe recommended dose of Sildenafil is 50 mg taken approximately 1 hour before sexual activity. Sildenafil may be taken anywhere from 4 hours to 0.5 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day.ContraindicationDanafil (Sildenafil Citrate) is contraindicated in patient with hypersensitivity to any component of this medication. Danafil (Sildenafil Citrate) potentiates the hypotensive effects of nitrates, so it is contraindicated in patients who are using organic nitrates, either regularly or intermittently.PrecautionCaution should be exercised if patients have any allergies to any other medicines or any other substances such as foods, preservatives or dyes, heart or blood vessel problems, sudden loss of eyesight in one or both eyes. Caution should be taken if patients have any of the following medical conditions such as diabetes, kidney or liver problems, leukaemia, multiple myeloma, any disease or deformity of penis, any bleeding disorder such as haemophilia, stomach ulcer, sickle cell anaemia, colour vision problems, sudden decrease or loss of hearing, or receiving any other treatment for impotence.Side EffectsThe adverse effects reported by <2% of patients treated with Sildenafil are headache, flushing, dyspepsia, nasal congestion, urinary tract infection, abnormal vision, diarrhea, dizziness, rash.Drug InteractionConcomitant use of Sildenafil with organic nitrates for angina may cause hypotension. Cimetidine, a medicine used to treat ulcers, some antibiotics including Erythromycin and Rifampicin, some protease inhibitors such as Ritonavir and Saquinavir for the treatment of HIV infection may increase the plasma concentration of Sildenafil. Some medicines used to treat fungal infections including Ketoconazole and Itraconazole may reduce the clearance of Sildenafil.Pregnancy & LactationPregnancy category B. In animal study shows that Sildenafil has no evidence of teratogenicity or embryotoxicity. There are no adequate and well-controlled studies of Sildenafil in pregnant women. Sildenafil is not indicated for use women.Storage ConditionStore in a cool and dry place away from light and moisture. Keep all medicines out of the reach of children...
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Ex Tax: Tk.50.15/=
Danafil 25 mg Tablet
Danafil 25 mg TabletDescription:Danafil (Sildenafil Citrate) is a selective inhibitor of cyclic Guanosine Monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) for treatment of erectile dysfunction. Danafil (Sildenafil Citrate) enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum that results in smooth muscle relaxation and inflow of blood to the corpus cavernosum.IndicationDanafil is indicated for the treatment of erectile dysfunction.Dosage & AdministrationThe recommended dose of Sildenafil is 50 mg taken approximately 1 hour before sexual activity. Sildenafil may be taken anywhere from 4 hours to 0.5 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day.ContraindicationDanafil (Sildenafil Citrate) is contraindicated in patient with hypersensitivity to any component of this medication. Danafil (Sildenafil Citrate) potentiates the hypotensive effects of nitrates, so it is contraindicated in patients who are using organic nitrates, either regularly or intermittently.PrecautionCaution should be exercised if patients have any allergies to any other medicines or any other substances such as foods, preservatives or dyes, heart or blood vessel problems, sudden loss of eyesight in one or both eyes. Caution should be taken if patients have any of the following medical conditions such as diabetes, kidney or liver problems, leukaemia, multiple myeloma, any disease or deformity of penis, any bleeding disorder such as haemophilia, stomach ulcer, sickle cell anaemia, colour vision problems, sudden decrease or loss of hearing, or receiving any other treatment for impotence.Side EffectsThe adverse effects reported by <2% of patients treated with Sildenafil are headache, flushing, dyspepsia, nasal congestion, urinary tract infection, abnormal vision, diarrhea, dizziness, rash.Drug InteractionConcomitant use of Sildenafil with organic nitrates for angina may cause hypotension. Cimetidine, a medicine used to treat ulcers, some antibiotics including Erythromycin and Rifampicin, some protease inhibitors such as Ritonavir and Saquinavir for the treatment of HIV infection may increase the plasma concentration of Sildenafil. Some medicines used to treat fungal infections including Ketoconazole and Itraconazole may reduce the clearance of Sildenafil.Pregnancy & LactationPregnancy category B. In animal study shows that Sildenafil has no evidence of teratogenicity or embryotoxicity. There are no adequate and well-controlled studies of Sildenafil in pregnant women. Sildenafil is not indicated for use women.Storage ConditionStore in a cool and dry place away from light and moisture. Keep all medicines out of the reach of children...
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Ex Tax: Tk.18.05/=
Danafil 50 mg Tablet, 1 Box
Danafil 50 mg Tablet, 1 BoxDescription:Danafil (Sildenafil Citrate) is a selective inhibitor of cyclic Guanosine Monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) for treatment of erectile dysfunction. Danafil (Sildenafil Citrate) enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum that results in smooth muscle relaxation and inflow of blood to the corpus cavernosum.IndicationDanafil is indicated for the treatment of erectile dysfunction.Dosage & AdministrationThe recommended dose of Sildenafil is 50 mg taken approximately 1 hour before sexual activity. Sildenafil may be taken anywhere from 4 hours to 0.5 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day.ContraindicationDanafil (Sildenafil Citrate) is contraindicated in patient with hypersensitivity to any component of this medication. Danafil (Sildenafil Citrate) potentiates the hypotensive effects of nitrates, so it is contraindicated in patients who are using organic nitrates, either regularly or intermittently.PrecautionCaution should be exercised if patients have any allergies to any other medicines or any other substances such as foods, preservatives or dyes, heart or blood vessel problems, sudden loss of eyesight in one or both eyes. Caution should be taken if patients have any of the following medical conditions such as diabetes, kidney or liver problems, leukaemia, multiple myeloma, any disease or deformity of penis, any bleeding disorder such as haemophilia, stomach ulcer, sickle cell anaemia, colour vision problems, sudden decrease or loss of hearing, or receiving any other treatment for impotence.Side EffectsThe adverse effects reported by <2% of patients treated with Sildenafil are headache, flushing, dyspepsia, nasal congestion, urinary tract infection, abnormal vision, diarrhea, dizziness, rash.Drug InteractionConcomitant use of Sildenafil with organic nitrates for angina may cause hypotension. Cimetidine, a medicine used to treat ulcers, some antibiotics including Erythromycin and Rifampicin, some protease inhibitors such as Ritonavir and Saquinavir for the treatment of HIV infection may increase the plasma concentration of Sildenafil. Some medicines used to treat fungal infections including Ketoconazole and Itraconazole may reduce the clearance of Sildenafil.Pregnancy & LactationPregnancy category B. In animal study shows that Sildenafil has no evidence of teratogenicity or embryotoxicity. There are no adequate and well-controlled studies of Sildenafil in pregnant women. Sildenafil is not indicated for use women.Storage ConditionStore in a cool and dry place away from light and moisture. Keep all medicines out of the reach of children...
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Ex Tax: Tk.120.36/=
Doxiva 100 ml Syp
Doxiva 100 ml SypDescription:Doxiva (Doxophylline) is a novel bronchodilator. It structurally differs from Theophylline due to the presence of a dioxolane group in position 7. Doxophylline selectively inhibits phosphodiesterase-4 thereby relaxes bronchial smooth muscle. However, differently from Theophylline, Doxophylline appears to have decreased affinities toward adenosine A1 and A2 receptors, which may account for the better safety profile of the drug. Doxophylline is reported to inhibit platelet activating factor (PAF) and generation of leukotriene production.IndicationDoxiva (Doxophylline) is used to treat asthma, COPD and bronchospasm.Dosage & AdministrationAdults : 1 tablet daily in the evening. On the basis of clinical response the dose may be increased to 1 tablet twice daily.Children (above 6 years of age) : 6 mg/kg twice daily.ContraindicationDoxophylline is contraindicated in acute myocardial infarction. It is also contraindicated in patients with hypotension, in lactating women & patients who have shown hypersensitivity to its componentsPrecautionThe half-life of xanthine derivatives is influenced by a number of known variables. It may be prolonged in patients with liver disease, in patients with congestive heart failure and in those patients taking certain other drugs like erythromycin, troleandomycin, lincomycin, allopurinol, cimetidine, propanolol and anti-flu vaccine. In these cases, a lower dose of Doxophylline may be needed. Phenytoin, other anticonvulsants and smoking may cause an increase in clearance with a shorter mean half-life. In these cases higher doses of Doxophylline may be needed.Side EffectsDoxophylline rarely causes serious side effects, however possible side effect are similar for taking excess amount of caffeine. These include: nausea, vomiting, headaches, upset stomach and heartburn.Drug InteractionDoxiva (Doxophylline) is used to treat asthma, COPD and bronchospasm.Pregnancy & LactationAnimal reproduction studies indicate that, Doxophylline does not cause fetal harm when administered to pregnant animals or can not affect reproduction capacity. However, since there is limited experience in human during pregnancy, xanthines should be given to pregnant women only if clearly needed. Doxophylline is contraindicated in nursing mothers.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Doxiva 200 mg Tab, 1 strip
Doxiva 200 mg Tab, 1 stripDescription:Doxiva (Doxophylline) is a novel bronchodilator. It structurally differs from Theophylline due to the presence of a dioxolane group in position 7. Doxophylline selectively inhibits phosphodiesterase-4 thereby relaxes bronchial smooth muscle. However, differently from Theophylline, Doxophylline appears to have decreased affinities toward adenosine A1 and A2 receptors, which may account for the better safety profile of the drug. Doxophylline is reported to inhibit platelet activating factor (PAF) and generation of leukotriene production.IndicationDoxiva (Doxophylline) is used to treat asthma, COPD and bronchospasm.Dosage & AdministrationAdults : 1 tablet daily in the evening. On the basis of clinical response the dose may be increased to 1 tablet twice daily.Children (above 6 years of age) : 6 mg/kg twice daily.ContraindicationDoxophylline is contraindicated in acute myocardial infarction. It is also contraindicated in patients with hypotension, in lactating women & patients who have shown hypersensitivity to its componentsPrecautionThe half-life of xanthine derivatives is influenced by a number of known variables. It may be prolonged in patients with liver disease, in patients with congestive heart failure and in those patients taking certain other drugs like erythromycin, troleandomycin, lincomycin, allopurinol, cimetidine, propanolol and anti-flu vaccine. In these cases, a lower dose of Doxophylline may be needed. Phenytoin, other anticonvulsants and smoking may cause an increase in clearance with a shorter mean half-life. In these cases higher doses of Doxophylline may be needed.Side EffectsDoxophylline rarely causes serious side effects, however possible side effect are similar for taking excess amount of caffeine. These include: nausea, vomiting, headaches, upset stomach and heartburn.Drug InteractionDoxiva (Doxophylline) is used to treat asthma, COPD and bronchospasm.Pregnancy & LactationAnimal reproduction studies indicate that, Doxophylline does not cause fetal harm when administered to pregnant animals or can not affect reproduction capacity. However, since there is limited experience in human during pregnancy, xanthines should be given to pregnant women only if clearly needed. Doxophylline is contraindicated in nursing mothers.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Doxiva 400 mg Tab, 1 strip
Doxiva 400 mg Tab, 1 stripDescription:Doxiva (Doxophylline) is a novel bronchodilator. It structurally differs from Theophylline due to the presence of a dioxolane group in position 7. Doxophylline selectively inhibits phosphodiesterase-4 thereby relaxes bronchial smooth muscle. However, differently from Theophylline, Doxophylline appears to have decreased affinities toward adenosine A1 and A2 receptors, which may account for the better safety profile of the drug. Doxophylline is reported to inhibit platelet activating factor (PAF) and generation of leukotriene production.IndicationDoxiva (Doxophylline) is used to treat asthma, COPD and bronchospasm.Dosage & AdministrationAdults : 1 tablet daily in the evening. On the basis of clinical response the dose may be increased to 1 tablet twice daily.Children (above 6 years of age) : 6 mg/kg twice daily.ContraindicationDoxophylline is contraindicated in acute myocardial infarction. It is also contraindicated in patients with hypotension, in lactating women & patients who have shown hypersensitivity to its componentsPrecautionThe half-life of xanthine derivatives is influenced by a number of known variables. It may be prolonged in patients with liver disease, in patients with congestive heart failure and in those patients taking certain other drugs like erythromycin, troleandomycin, lincomycin, allopurinol, cimetidine, propanolol and anti-flu vaccine. In these cases, a lower dose of Doxophylline may be needed. Phenytoin, other anticonvulsants and smoking may cause an increase in clearance with a shorter mean half-life. In these cases higher doses of Doxophylline may be needed.Side EffectsDoxophylline rarely causes serious side effects, however possible side effect are similar for taking excess amount of caffeine. These include: nausea, vomiting, headaches, upset stomach and heartburn.Drug InteractionDoxiva (Doxophylline) is used to treat asthma, COPD and bronchospasm.Pregnancy & LactationAnimal reproduction studies indicate that, Doxophylline does not cause fetal harm when administered to pregnant animals or can not affect reproduction capacity. However, since there is limited experience in human during pregnancy, xanthines should be given to pregnant women only if clearly needed. Doxophylline is contraindicated in nursing mothers.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Fixpro 200 Cap
Fixpro 200 CapDescription:Fixpro (Cefixime) is a third generation semisynthetic cephalosporin antibiotic for oral administration. It is bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations. It is highly stable in the presence of Beta-lactamase enzyme. As a result, many organisms resistant to penicillins and some cephalsporins due to the presence of beta-lactamases, may be susceptible to Cefixime. Absorption of it is about 40% to 50% whether administered with or without food.IndicationFixpro (Cefixime) is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms:Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis. Otitis Media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes. Pharyngitis and tonsillitis caused by Streptococcus pyogenes. Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae. Uncomplicated gonorrhoea (cervical/urethral) caused by Neisseria gonorrhoeae.Dosage & AdministrationAdult and children over 12 years: The recommended adult dose is 200-400 mg (1 to 2 capsules) daily, given either as a single dose or in two divided doses for 7-14 days depending on the severity of the infection. For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of Cefixime 400 mg is recommended. Single 800 mg may be given if essential.Children upto 12 years: Usually 8mg/kg/day given as a single dose or in two divided doses or may be given as following :½-1 year : 3.75 ml or 75 mg daily.1-4 years : 5 ml or 100 mg daily.5-10 years : 10 ml or 200 mg daily.11-12 years : 15 ml or 300 mg daily.The safety and efficacy of Cefixime has not been established in children aged less than 6 months.The usual course of treatment is 7 days. This may be continued for up to 14 days as in typhoid or in any severe infection, if physicians desire. In typhoid fever, dosage should be 10mg/kg/day for 14 days.ContraindicationIt is contraindicated in hypersensitivity to Cefixime or other cephalosporins.PrecautionThe drug should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis. The drug should be given with caution in patients with marked impaired renal function as well as those undergoing continuous ambulatory peritoneal dialysis and hemodialysis. Dosage adjustment is only necessary in severe renal failure (creatinine clearance < 20 ml.min-1), in that case a dose of 200 mg once daily should not be exceeded.Side EffectsThe drug is generally well tolerated. The most frequent side effects are diarrhoea and stool changes; that have been more commonly associated with higher doses. Other side effects are nausea, abdominal pain, dyspepsia, vomiting, flatulence, headache and dizziness. Allergies in the form of rash, pruritus, urticaria, drug fever and arthralgia have been reported. These reactions usually subsided upon dicontinuation of therapy.Drug InteractionCarbamazepine: Concomitant use elevates the carbamazepine level. Warfarin and other anticoagulants: Concomitant use increases prothrombin time.Pregnancy & LactationUS FDA Pregnancy Category of Cefixime is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. It is not known that Cefixime is excreted in human milk. So, caution should be exercised when Cefixime is administered to a nursing woman.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.30.21/=
Fixpro 400 Cap
Fixpro 400 CapDescription:Fixpro (Cefixime) is a third generation semisynthetic cephalosporin antibiotic for oral administration. It is bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations. It is highly stable in the presence of Beta-lactamase enzyme. As a result, many organisms resistant to penicillins and some cephalsporins due to the presence of beta-lactamases, may be susceptible to Cefixime. Absorption of it is about 40% to 50% whether administered with or without food.IndicationFixpro (Cefixime) is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms:Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis. Otitis Media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes. Pharyngitis and tonsillitis caused by Streptococcus pyogenes. Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae. Uncomplicated gonorrhoea (cervical/urethral) caused by Neisseria gonorrhoeae.Dosage & AdministrationAdult and children over 12 years: The recommended adult dose is 200-400 mg (1 to 2 capsules) daily, given either as a single dose or in two divided doses for 7-14 days depending on the severity of the infection. For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of Cefixime 400 mg is recommended. Single 800 mg may be given if essential.Children upto 12 years: Usually 8mg/kg/day given as a single dose or in two divided doses or may be given as following :½-1 year : 3.75 ml or 75 mg daily.1-4 years : 5 ml or 100 mg daily.5-10 years : 10 ml or 200 mg daily.11-12 years : 15 ml or 300 mg daily.The safety and efficacy of Cefixime has not been established in children aged less than 6 months.The usual course of treatment is 7 days. This may be continued for up to 14 days as in typhoid or in any severe infection, if physicians desire. In typhoid fever, dosage should be 10mg/kg/day for 14 days.ContraindicationIt is contraindicated in hypersensitivity to Cefixime or other cephalosporins.PrecautionThe drug should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis. The drug should be given with caution in patients with marked impaired renal function as well as those undergoing continuous ambulatory peritoneal dialysis and hemodialysis. Dosage adjustment is only necessary in severe renal failure (creatinine clearance < 20 ml.min-1), in that case a dose of 200 mg once daily should not be exceeded.Side EffectsThe drug is generally well tolerated. The most frequent side effects are diarrhoea and stool changes; that have been more commonly associated with higher doses. Other side effects are nausea, abdominal pain, dyspepsia, vomiting, flatulence, headache and dizziness. Allergies in the form of rash, pruritus, urticaria, drug fever and arthralgia have been reported. These reactions usually subsided upon dicontinuation of therapy.Drug InteractionCarbamazepine: Concomitant use elevates the carbamazepine level. Warfarin and other anticoagulants: Concomitant use increases prothrombin time.Pregnancy & LactationUS FDA Pregnancy Category of Cefixime is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. It is not known that Cefixime is excreted in human milk. So, caution should be exercised when Cefixime is administered to a nursing woman.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Fixpro 50 ml Susp.
Fixpro 50 ml Susp.Description:Fixpro (Cefixime) is a third generation semisynthetic cephalosporin antibiotic for oral administration. It is bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations. It is highly stable in the presence of Beta-lactamase enzyme. As a result, many organisms resistant to penicillins and some cephalsporins due to the presence of beta-lactamases, may be susceptible to Cefixime. Absorption of it is about 40% to 50% whether administered with or without food.IndicationFixpro (Cefixime) is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms:Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis. Otitis Media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes. Pharyngitis and tonsillitis caused by Streptococcus pyogenes. Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae. Uncomplicated gonorrhoea (cervical/urethral) caused by Neisseria gonorrhoeae.Dosage & AdministrationAdult and children over 12 years: The recommended adult dose is 200-400 mg (1 to 2 capsules) daily, given either as a single dose or in two divided doses for 7-14 days depending on the severity of the infection. For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of Cefixime 400 mg is recommended. Single 800 mg may be given if essential.Children upto 12 years: Usually 8mg/kg/day given as a single dose or in two divided doses or may be given as following :½-1 year : 3.75 ml or 75 mg daily.1-4 years : 5 ml or 100 mg daily.5-10 years : 10 ml or 200 mg daily.11-12 years : 15 ml or 300 mg daily.The safety and efficacy of Cefixime has not been established in children aged less than 6 months.The usual course of treatment is 7 days. This may be continued for up to 14 days as in typhoid or in any severe infection, if physicians desire. In typhoid fever, dosage should be 10mg/kg/day for 14 days.ContraindicationIt is contraindicated in hypersensitivity to Cefixime or other cephalosporins.PrecautionThe drug should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis. The drug should be given with caution in patients with marked impaired renal function as well as those undergoing continuous ambulatory peritoneal dialysis and hemodialysis. Dosage adjustment is only necessary in severe renal failure (creatinine clearance < 20 ml.min-1), in that case a dose of 200 mg once daily should not be exceeded.Side EffectsThe drug is generally well tolerated. The most frequent side effects are diarrhoea and stool changes; that have been more commonly associated with higher doses. Other side effects are nausea, abdominal pain, dyspepsia, vomiting, flatulence, headache and dizziness. Allergies in the form of rash, pruritus, urticaria, drug fever and arthralgia have been reported. These reactions usually subsided upon dicontinuation of therapy.Drug InteractionCarbamazepine: Concomitant use elevates the carbamazepine level. Warfarin and other anticoagulants: Concomitant use increases prothrombin time.Pregnancy & LactationUS FDA Pregnancy Category of Cefixime is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. It is not known that Cefixime is excreted in human milk. So, caution should be exercised when Cefixime is administered to a nursing woman.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.196.33/=
Flexivan ER Tablet 200 mg, 1 strip
Flexivan ER Tablet 200 mg, 1 stripDescription:Flexivan ER (Aceclofenac) is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug.CompositionEach extended release tablet contains Aceclofenac BP 200 mg.IndicationAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma and lumbago.Dosage & AdministrationThe recommended dose in adults is one tablet (Flexivan ER 200 mg) daily or as prescribed by the physician.ContraindicationAceclofenac is contraindicated in patients with known hypersensitivity to it or in whom aspirin or NSAIDs precipitate attacks of asthma.PrecautionCaution should be exercised to patients with active or suspected peptic ulcer or gastro-intestinal bleeding moderate to severe hepatic impairment and cardiac or renal impairment. Caution should also be exercised in patients suffering from dizziness or urticaria.Side EffectsMajority of side effects are minor in nature and reversible. These are dyspepsia, abdominal pain, nausea, rash and urticaria.Drug InteractionNo significant drug interactions has not been observed but close monitoring of patients is required when it is used with lithium and digoxin, oral antidiabetic agents, anticoagulants, diuretics and other analgesics.Pregnancy & LactationThe use of Aceclofenac should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.Storage Conditionkeep in a dry place away from light and heat. Keep out of the reach of children...
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Florocin 500 mg Tablet
Description:Florocin (Ciprofloxacin) is a synthetic fluoroquinolone. It has bacteriocidal activity against a wide range of gram-positive and gram-negative organisms. It inhibits bacterial DNA synthesis by binding with the bacterial enzyme-DNA gyrase and topoisomerase IV which are responsible for DNA supercoiling.IndicationIt is indicated for the treatment of uncomplicated and complicated urinary tract infections, chronic bacterial prostatitis, lower respiratory tract infections, acute sinusitis, skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections (used in combination with metronidazole), infectious diarrhoea, typhoid fever, urethral & cervical gonococcal infection and surgical prophylaxis.Dosage & AdministrationUrinary tract infections : 250-500 mg twice daily.Chronic prostatitis : 500 mg twice daily for 28 days.Respiratory tract infections : 250-750 mg twice daily.Gonorrhoea : 500 mg as a single dose.Surgical prophylaxis : 750 mg, 60-90 minutes before procedure.Pseudomonal lower respiratory tract infection in cystic fibrosis : 750 mg twice daily for adult and up to 20 mg/kg twice daily for child (5-17 years). <>Most other infections : 500-750 mg twice daily.Child and Adolescent : Based on benefit outweighs risk, 5-15 mg/kg (max. 750 mg) twice daily may be used.The duration of therapy depends on the type and severity of infection. For most infections, therapy should be continued for at least 48 hours after the patients become asymptomatic. The usual duration is 1-2 weeks but severe or complicated infections may require more prolonged therapy. Therapy may need to be continued for 4-6 weeks or longer for the treatment of bone and joint infections. Infectious diarrhoea generally is treated for 3-7 days, although less prolonged therapy may be adequate.To get completely palatable suspension use after 30 minutes of reconstitution.ContraindicationIt is contraindicated in patients who have known hypersensitivity to Ciprofloxacin or other quinolones.PrecautionPatients receiving Ciprofloxacin should be instructed to drink fluids liberally. It should be used with caution in patients with suspected or known CNS disorders such as epilepsy or other factors which predispose to seizures and convulsion.Side EffectsSide effects include- nausea and other gastrointestinal disturbances, headache, dizziness, joint pain and skin rashes. Crystaluria has occurred with high doses.Drug InteractionConcurrent administration of Ciprofloxacin should be avoided with magnesium or aluminum containing antacids or sucralfate or with other products containing calcium, iron or zinc. These products may be taken two hours after or six hours before Ciprofloxacin. Ciprofloxacin should not be taken concurrently with milk or other dairy products, since absorption of Ciprofloxacin may be significantly reduced. Dietary calcium is a part of a meal, however, does not significantly affect the absorption of Ciprofloxacin.Pregnancy & LactationUS FDA Pregnancy category of Ciprofloxacin is C. Like other quinolones, Ciprofloxacin causes arthropathy in immature animals and therefore its use during pregnancy and lactation is not recommended.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Florocin 60 ml Suspension
Florocin 60 ml SuspensionDescription:Florocin (Ciprofloxacin) is a synthetic fluoroquinolone. It has bacteriocidal activity against a wide range of gram-positive and gram-negative organisms. It inhibits bacterial DNA synthesis by binding with the bacterial enzyme-DNA gyrase and topoisomerase IV which are responsible for DNA supercoiling.IndicationIt is indicated for the treatment of uncomplicated and complicated urinary tract infections, chronic bacterial prostatitis, lower respiratory tract infections, acute sinusitis, skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections (used in combination with metronidazole), infectious diarrhoea, typhoid fever, urethral & cervical gonococcal infection and surgical prophylaxis.Dosage & AdministrationUrinary tract infections : 250-500 mg twice daily.Chronic prostatitis : 500 mg twice daily for 28 days.Respiratory tract infections : 250-750 mg twice daily.Gonorrhoea : 500 mg as a single dose.Surgical prophylaxis : 750 mg, 60-90 minutes before procedure.Pseudomonal lower respiratory tract infection in cystic fibrosis : 750 mg twice daily for adult and up to 20 mg/kg twice daily for child (5-17 years). <>Most other infections : 500-750 mg twice daily.Child and Adolescent : Based on benefit outweighs risk, 5-15 mg/kg (max. 750 mg) twice daily may be used.The duration of therapy depends on the type and severity of infection. For most infections, therapy should be continued for at least 48 hours after the patients become asymptomatic. The usual duration is 1-2 weeks but severe or complicated infections may require more prolonged therapy. Therapy may need to be continued for 4-6 weeks or longer for the treatment of bone and joint infections. Infectious diarrhoea generally is treated for 3-7 days, although less prolonged therapy may be adequate.To get completely palatable suspension use after 30 minutes of reconstitution.ContraindicationIt is contraindicated in patients who have known hypersensitivity to Ciprofloxacin or other quinolones.PrecautionPatients receiving Ciprofloxacin should be instructed to drink fluids liberally. It should be used with caution in patients with suspected or known CNS disorders such as epilepsy or other factors which predispose to seizures and convulsion.Side EffectsSide effects include- nausea and other gastrointestinal disturbances, headache, dizziness, joint pain and skin rashes. Crystaluria has occurred with high doses.Drug InteractionConcurrent administration of Ciprofloxacin should be avoided with magnesium or aluminum containing antacids or sucralfate or with other products containing calcium, iron or zinc. These products may be taken two hours after or six hours before Ciprofloxacin. Ciprofloxacin should not be taken concurrently with milk or other dairy products, since absorption of Ciprofloxacin may be significantly reduced. Dietary calcium is a part of a meal, however, does not significantly affect the absorption of Ciprofloxacin.Pregnancy & LactationUS FDA Pregnancy category of Ciprofloxacin is C. Like other quinolones, Ciprofloxacin causes arthropathy in immature animals and therefore its use during pregnancy and lactation is not recommended.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Lijenta 5 Tab, 1 strip
Lijenta 5 Tab, 1 stripDescription:Lijenta 5 is an inhibitor of DPP-4 , an enzyme that degrades the incretin hormones GLP-1 and GIP. Thus, Linagliptin increases the concentratins of active incretin hormones, stimulating the release of insulin from pancreatic beta cells in a glucose-dependent manner and decreasing the secretion of glucangon from pancreatic alpha cells in the circulation.Thus it improves glycemic control in patients with type 2 diabetes mellitus.IndicationLijenta 5 is indicated in the treatment of type 2 diabetes mellitus to improve glycaemic control in adults. As monotherapy-in patients inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to intolerance or contraindicated due to renal impairment. As combination therapy-in combination with metformin when diet and exercise plus metformin alone do not provide adequate glycaemic control-in combination with a sulphonylurea and metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycaemic control.Dosage & Administration5 mg once daily. If added to metformin, the dose of metformin should be maintained and linagliptin administered concomitantly. When used in combination with a sulfonylurea, a lower dose of the sulphonylurea may be considered to reduce the risk of hypoglycaemia.Patients with renal impairment: no dose adjustment required. Linagliptin can be taken with or without a meal at any time of the day.ContraindicationHypersensitivity to the active substance or to any of the excipients.PrecautionLinagliptin should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.Side EffectsThere may be hypoglycaemia, nasopharyngitis, cough and pancreatitis in combination with metformin and sulfonylurea.Drug InteractionLinagliptin is a weak competitive and a weak to moderate mechanism-based inhibitor of CYP isozyme CYP3A4, but does not inhibit other CYP isozymes. The risk for clinically meaningful interactions by other medicinal products on linagliptin is low and in clinical studies linagliptin had no clinically relevant effect on the pharmacokinetics of metformin, glyburide, simvastatin, warfarin, digoxin or oral contraceptives.Pregnancy & LactationAvoid use during pregnancy. A risk to the breast-fed child cannot be excluded.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Lijenta-M 500 Tab, 1 strip
Lijenta-M 500 Tab, 1 stripDescription:Lijenta-M is a combination of linagliptin and Metformin Hydrochloride with complementary mechanism of action to improve glycemic control in patients with type 2 diabetes mellitus. Linagliptin is an inhibitor of DPP-4 (dipeptidyl peptidase-4), an enzyme that degrades the incretin hormones GLP-1 (glucagon like peptide-1) and GIP (glucose dependent insulinotropic polypeptide). Thus, Linagliptin increases the concentrations of active incretin hormones, stimulating the release of insulin from pancreatic beta cells in a glucose-dependent manner and decreasing the secretion of glucagon from pancreatic alpha cells in the circulation.Metformin Hydrochloride is a biguanide type oral antihyperglycemic drug used in the management of type 2 diabetes. It lowers both basal and postprandial plasma glucose. Its mechanism of action is different from those of sulfonylureas and it does not produce hypoglycemia. Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity by an increase in peripheral glucose uptake and utilization.IndicationLijenta-M is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both linagliptin and metformin is appropriate.Dosage & AdministrationThe dosage of Lijenta-M should be individualized on the basis of both effectiveness and tolerability. Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals. Dose escalation should be gradual to reduce the gastrointestinal (GI) side effects associated with Metformin use.Recommended starting dose: In patients currently not treated with Metformin, initiate treatment with 2.5 mg Linagliptin and 500 mg Metformin Hydrochloride twice daily.In patients already treated with Metformin, start with 2.5 mg Linagliptin and the current dose of Metformin Hydrochloride twice daily.Patients already treated with linagliptin and metformin, individual components may be switched to this combination containing the same doses of each component.ContraindicationAlthough Linagliptin undergoes minimal renal excretion, Metformin is known to be substantially excreted by the kidney. The risk of Metformin accumulation and lactic acidosis increases with the degree of renal impairment. Therefore, this combination is contraindicated in patients with renal impairment. It is also contraindicated in acute or chronic metabolic acidosis (diabetic ketoacidosis) and in hypersensitivity to Linagliptin or Metformin.PrecautionIn a patient with lactic acidosis who is taking Metformin, the drug should be discontinued immediately and supportive therapy promptly instituted. There have been postmarketing reports of acute pancreatitis. If pancreatitis is suspected, promptly discontinue Lijenta-M. Temporarily discontinue Lijenta-M in patients undergoing radiologic studies with intravascular administration of iodinated contrast materials or any surgical procedures necessitating restricted intake of food and fluids. Metformin may lower Vitamin B12 levels; so hematologic parameters shoud be monitored annually.Side EffectsMost common side effects are nasopharyngitis and diarrhea. Hypoglycemia is more common in patients treated with this combination and sulfonylureas.Drug InteractionCationic drugs (amiloride, digoxin, morphine, ranitidine, trimethoprim etc.): May reduce metformin elimination. P-glycoprotien/CYP3A4 inducer (i.e. rifampin): The efficacy of Lijenta-M may be reduced when administered in combination.Pregnancy & LactationPregnancy category B. There are no adequate and well-controlled studies in pregnant women with this combination or its individual component; so it should be used during pregnancy only if clearly needed. Caution should also be excercised when it is administered to a lactating mother.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.120.00/=
Lijenta-M 850 Tab, 1 strip
Lijenta-M 850 Tab, 1 stripDescription:Lijenta-M is a combination of linagliptin and Metformin Hydrochloride with complementary mechanism of action to improve glycemic control in patients with type 2 diabetes mellitus. Linagliptin is an inhibitor of DPP-4 (dipeptidyl peptidase-4), an enzyme that degrades the incretin hormones GLP-1 (glucagon like peptide-1) and GIP (glucose dependent insulinotropic polypeptide). Thus, Linagliptin increases the concentrations of active incretin hormones, stimulating the release of insulin from pancreatic beta cells in a glucose-dependent manner and decreasing the secretion of glucagon from pancreatic alpha cells in the circulation.Metformin Hydrochloride is a biguanide type oral antihyperglycemic drug used in the management of type 2 diabetes. It lowers both basal and postprandial plasma glucose. Its mechanism of action is different from those of sulfonylureas and it does not produce hypoglycemia. Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity by an increase in peripheral glucose uptake and utilization.IndicationLijenta-M is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both linagliptin and metformin is appropriate.Dosage & AdministrationThe dosage of Lijenta-M should be individualized on the basis of both effectiveness and tolerability. Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals. Dose escalation should be gradual to reduce the gastrointestinal (GI) side effects associated with Metformin use.Recommended starting dose: In patients currently not treated with Metformin, initiate treatment with 2.5 mg Linagliptin and 500 mg Metformin Hydrochloride twice daily.In patients already treated with Metformin, start with 2.5 mg Linagliptin and the current dose of Metformin Hydrochloride twice daily.Patients already treated with linagliptin and metformin, individual components may be switched to this combination containing the same doses of each component.ContraindicationAlthough Linagliptin undergoes minimal renal excretion, Metformin is known to be substantially excreted by the kidney. The risk of Metformin accumulation and lactic acidosis increases with the degree of renal impairment. Therefore, this combination is contraindicated in patients with renal impairment. It is also contraindicated in acute or chronic metabolic acidosis (diabetic ketoacidosis) and in hypersensitivity to Linagliptin or Metformin.PrecautionIn a patient with lactic acidosis who is taking Metformin, the drug should be discontinued immediately and supportive therapy promptly instituted. There have been postmarketing reports of acute pancreatitis. If pancreatitis is suspected, promptly discontinue Lijenta-M. Temporarily discontinue Lijenta-M in patients undergoing radiologic studies with intravascular administration of iodinated contrast materials or any surgical procedures necessitating restricted intake of food and fluids. Metformin may lower Vitamin B12 levels; so hematologic parameters shoud be monitored annually.Side EffectsMost common side effects are nasopharyngitis and diarrhea. Hypoglycemia is more common in patients treated with this combination and sulfonylureas.Drug InteractionCationic drugs (amiloride, digoxin, morphine, ranitidine, trimethoprim etc.): May reduce metformin elimination. P-glycoprotien/CYP3A4 inducer (i.e. rifampin): The efficacy of Lijenta-M may be reduced when administered in combination.Pregnancy & LactationPregnancy category B. There are no adequate and well-controlled studies in pregnant women with this combination or its individual component; so it should be used during pregnancy only if clearly needed. Caution should also be excercised when it is administered to a lactating mother.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.112.00/=
Lovapres 5mg Tablet, 1 Strip
Lovapres 5mg Tablet, 1 StripDescription:Lovapres(Amlodipine) is a long-acting calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Thus it causes reduction in peripheral vascular resistance and contractile process in cardiac muscle and reduces blood pressure.IndicationLovapres(Amlodipine) is a calcium channel blocker and may be used alone or in combination with other antihypertensive and antianginal agents for the treatment of Hypertension and Coronary Artery Disease (such as Chronic Stable Angina, Vasospastic Angina and Angiographically Documented Coronary Artery Disease in patients without heart failure or an ejection fraction < 40%) .Dosage & AdministrationAdult: Starting dose 5 mg once daily with maximum dose 10 mg once daily. Small, Fragile and Elderly patients or patients with hepatic insufficiency: Starting dose 2.5 mg once daily.Pediatric: Starting dose 2.5 mg to 5 mg once daily.ContraindicationIt is contraindicated in patients with known sensitivity to AmlodipinePrecautionSymptomatic hypotension is possible, particularly in patients with severe aortic stenosis. However, because of the gradual onset of action, acute hypotension is unlikely. Worsening angina and acute myocardial infarction can develop after starting or increasing the dose of Amlodipine, particularly in patients with severe obstructive coronary artery disease. Titrate slowly when administering calcium channel blockers to patients with severe hepatic impairment.Side EffectsMost common side effects are headache and edema which occurred in a dose related manner. Other side effects not dose related but reported with an incidence >1.0% are headache, fatigue, nausea, abdominal pain and somnolence.Drug InteractionAmlodipine has been safely administered with thiazide diuretics, alpha blockers, beta blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerine, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs. Amlodipine has no effect on protein binding of digoxin, phenytoin, warfarin, or indomethacin. Administration of Amlodipine with grapefruit or grapefruit juice is not recommended as bioavailability may be increased in some patients resulting in increased blood pressure lowering effects.Pregnancy & LactationPregnancy Category C. There are no adequate and well-controlled studies of Amlodipine in pregnant women. Amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Amlodipine is excreted in human milk. In the absence of this information, it is recommended that nursing be discontinued while Amlodipine is administered.Storage Conditionkeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.50.00/=
Metavas MR 35 mg Tablet, 1 Strip
Metavas MR 35 mg Tablet, 1 StripDescription:Metavas MR (Trimetazidine Dihydrochloride) is the first 3- keto acyl CoA thiolase inhibitor (KAT), a metabolic anti-ischemic agent with proven benefits for all coronary patients. Metavas MR (Trimetazidine) inhibits fatty acid pathway by inhibiting 3-keto acyl CoA thiolase enzyme and transfers oxygen to glucose pathway. Since glucose pathway is more efficient in producing energy, the same oxygen produces more energy and makes the heat more active. Moreover, the aerobic oxidation of glucose stops production of lactic acid, which prevents angina pectoris.CompositionEach modified release tablet contains Trimetazidine Dihydrochloride BP 35 mg.IndicationMetavas MR (Trimetazidine Dihydrochloride) is indicated in adults as add-on therapy for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled by or intolerant to first-line antianginal therapies.Dosage & AdministrationThe recommended dose of Trimetazidine is 35 mg twice daily during meals. The benefit of the treatment should be assessed after three months and Trimetazidine should be discontinued if there is no treatment response.ContraindicationTrimetazidine is contraindicated in patients who have hypersensitivity to the active substance or to any of the excipients. It is also is contraindicated in patients with Parkinson disease, parkinsonian symptoms, tremors, restlessleg movement disorders, severe renal impairment.PrecautionTrimetazidine is not a curative treatment for angina attacks, nor an initial treatment for unstable angina pectoris. It is not a treatment for myocardial infarction.Side EffectsTrimetazidine is safe and well tolerated. The Common side effects associated with Trimetazidine are dizziness, headache, abdominal pain, diarrhoea, dyspepsia, nausea, vomiting, rash, pruritus, urticaria and astheniaDrug InteractionNo drug interactions so far have been reported. In particular, no interactions have been reported with beta-blockers, calcium antagonists, nitrates, heparin, hypolipidemic agents or digitalis preparation.Pregnancy & LactationThere are no data from the use of Trimetazidine in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. As a precautionary measure, it is preferable to avoid the use of Trimetazidine during pregnancy. It is unknown whether Trimetazidine is excreted in human milk. A risk to the newborns/infants cannot be excluded. Trimetazidine should not be used during breast-feeding.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.60.00/=
Montiva 10 Tablet, 1 strip
Montiva 10 Tablet, 1 stripDescription:Montelukast is a selective and orally active competitive cysteinyl leukotriene receptor antagonist, that inhibits the cysteinyl leukotriene (CysLT1) receptor to occupy the receptor. The cysteinyl leukotriene (CysLT1) receptor is found in the human airway with which cysteinyl leukotrienes bind to cause edema and smooth muscle contraction. Cysteinyl leukotrienes (CysLTs) have been correlated with the pathophysiology of asthma and allergic rhinitis.IndicationMontelukast is indicated for the prophylaxis and chronic treatment of asthma, exercise-induced bronchoconstriction (EIB) and seasonal allergic rhinitis.Dosage & AdministrationFor adults and adolescents (15 years of age and older): 10 mg tablet once daily in the evening.Children 6-14 years: 5 mg Oroflash tablet once daily in the evening.ContraindicationMontelukast is contraindicated to patients with hypersensitivity to any component of this product.PrecautionMontelukast is not indicated for use in the reversal of bronchospasm in acute asthma attacks. Montelukast should not be abruptly substituted for inhaled or oral corticosteroids. Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Montelukast. Patients should be alert for neuropsychiatric events. Physician should be alert to eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications presenting in their patients.Side EffectsGenerally, Montelukast is well-tolerated. Side effects include fever, headache, cough, abdominal pain, diarrhea, otitis media, influenza, rhinorrhea, upper respiratory tract infection.Drug InteractionMontelukast has been administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma. In drug-interaction studies, the recommended clinical dose of montelukast did not have clinically important effects on the pharmacokinetics of the following medical products: theophylline, prednisolone, prednisone, oral contraceptives, terfenadine, digoxin and warfarin.Pregnancy & LactationIn Pregnancy: Montelukast is a pregnancy category B drug .There is no adequate and well-controlled studies in pregnant women. Montelukast should be used during pregnancy only if clearly needed.In Lactation: It is not known if Montelukast is excreted in human milk. Caution should be exercised when Montelukast is given to a nursing mother.Storage ConditionKeep in dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.150.00/=
Montiva 4 mg Tablet, 1 strip
Montiva 4 mg Tablet, 1 stripDescription:Montelukast is a selective and orally active competitive cysteinyl leukotriene receptor antagonist, that inhibits the cysteinyl leukotriene (CysLT1) receptor to occupy the receptor. The cysteinyl leukotriene (CysLT1) receptor is found in the human airway with which cysteinyl leukotrienes bind to cause edema and smooth muscle contraction. Cysteinyl leukotrienes (CysLTs) have been correlated with the pathophysiology of asthma and allergic rhinitis.IndicationMontelukast is indicated for the prophylaxis and chronic treatment of asthma, exercise-induced bronchoconstriction (EIB) and seasonal allergic rhinitis.Dosage & AdministrationFor adults and adolescents (15 years of age and older): 10 mg tablet once daily in the evening.Children 6-14 years: 5 mg Oroflash tablet once daily in the evening.ContraindicationMontelukast is contraindicated to patients with hypersensitivity to any component of this product.PrecautionMontelukast is not indicated for use in the reversal of bronchospasm in acute asthma attacks. Montelukast should not be abruptly substituted for inhaled or oral corticosteroids. Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Montelukast. Patients should be alert for neuropsychiatric events. Physician should be alert to eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications presenting in their patients.Side EffectsGenerally, Montelukast is well-tolerated. Side effects include fever, headache, cough, abdominal pain, diarrhea, otitis media, influenza, rhinorrhea, upper respiratory tract infection.Drug InteractionMontelukast has been administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma. In drug-interaction studies, the recommended clinical dose of montelukast did not have clinically important effects on the pharmacokinetics of the following medical products: theophylline, prednisolone, prednisone, oral contraceptives, terfenadine, digoxin and warfarin.Pregnancy & LactationIn Pregnancy: Montelukast is a pregnancy category B drug .There is no adequate and well-controlled studies in pregnant women. Montelukast should be used during pregnancy only if clearly needed.In Lactation: It is not known if Montelukast is excreted in human milk. Caution should be exercised when Montelukast is given to a nursing mother.Storage ConditionKeep in dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.60.00/=
Montiva 5 mg Tablet, 1 strip
Montiva 5 mg Tablet, 1 stripDescription:Montelukast is a selective and orally active competitive cysteinyl leukotriene receptor antagonist, that inhibits the cysteinyl leukotriene (CysLT1) receptor to occupy the receptor. The cysteinyl leukotriene (CysLT1) receptor is found in the human airway with which cysteinyl leukotrienes bind to cause edema and smooth muscle contraction. Cysteinyl leukotrienes (CysLTs) have been correlated with the pathophysiology of asthma and allergic rhinitis.IndicationMontelukast is indicated for the prophylaxis and chronic treatment of asthma, exercise-induced bronchoconstriction (EIB) and seasonal allergic rhinitis.Dosage & AdministrationFor adults and adolescents (15 years of age and older): 10 mg tablet once daily in the evening.Children 6-14 years: 5 mg Oroflash tablet once daily in the evening.ContraindicationMontelukast is contraindicated to patients with hypersensitivity to any component of this product.PrecautionMontelukast is not indicated for use in the reversal of bronchospasm in acute asthma attacks. Montelukast should not be abruptly substituted for inhaled or oral corticosteroids. Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking Montelukast. Patients should be alert for neuropsychiatric events. Physician should be alert to eosinophilia, vasculitic rash, worsening pulmonary symptoms, cardiac complications presenting in their patients.Side EffectsGenerally, Montelukast is well-tolerated. Side effects include fever, headache, cough, abdominal pain, diarrhea, otitis media, influenza, rhinorrhea, upper respiratory tract infection.Drug InteractionMontelukast has been administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma. In drug-interaction studies, the recommended clinical dose of montelukast did not have clinically important effects on the pharmacokinetics of the following medical products: theophylline, prednisolone, prednisone, oral contraceptives, terfenadine, digoxin and warfarin.Pregnancy & LactationIn Pregnancy: Montelukast is a pregnancy category B drug .There is no adequate and well-controlled studies in pregnant women. Montelukast should be used during pregnancy only if clearly needed.In Lactation: It is not known if Montelukast is excreted in human milk. Caution should be exercised when Montelukast is given to a nursing mother.Storage ConditionKeep in dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.80.00/=
Nipro Gold Tablet, 1 strip
Nipro Gold Tablet, 1 stripDescription:Nipro Gold is a film coated tablet, which combines 32 high potency vitamins and minerals. This preparation maintains a healthy body and active life-style.CompositionEach film coated tablet contains Vitamin A 5000 IU, Vitamin C 60 mg, Vitamin D 400 IU, Vitamin E 30 IU, Vitamin K 25 mcg, Vitamin B1 (Thiamine) 1.5 mg, Vitamin B2 (Riboflavin) 1.7 mg, Vitamin B3 (Niacin) 20 mg, Vitamin B6 (Pyridoxine) 2 mg, Folic acid 400 mcg, Biotin 30 mcg, Pantothenate 10 mg, Calcium 162 mg, Iron 18 mg, Phosphorous 109 mg, Iodine 150 mcg, Magnesium 100 mg, Zinc 15 mg, Selenium 20 mcg, Copper 2 mg, Manganese 2 mg, Chromium 120 mcg, Molybdenum 75 mcg, Chloride 72 mg, Potassium 80 mg, Boron 150 mcg, Nickel 5 mcg, Silicon 2 mg, Tin 10 mcg, Vanadium 10 mcg, Lutein 250 mcg and Cyanocobalamin 6 mcg.IndicationNipro Gold is indicated for the prevention and treatment of vitamins & minerals deficiencies. As a complete daily nutritional supplement, it is also indicated to meet the increased demand for vitamins and minerals in the conditions like physical and emotional stress, chronic diseases, infection illness, osteoporosis, injuries or wound, surgery, poor digestion, old age, pregnancy and lactation, poor appetite, excess dieting, exposure to environmental pollution, heavy exercise etc.Dosage & AdministrationOne tablet daily or as recommended by the physician.ContraindicationThis product is contraindicated in patients with known hypersensitivity to any of the ingredients.PrecautionLong term intake of high level of vitamin A (excluding that sourced from beta carotene) may increase the risk of osteoporosis in postmenopausal women.Side EffectsGenerally, this preparation is well tolerated. Diarrhorea may occasionally occur during treatment with beta carotene and the skin may assume a slightly yellow discoloration. Vitamin C and vitamin E may cause diarrhoea and other gastrointestinal disturbances.Drug InteractionNo drug interactions have been reported.Pregnancy & LactationRecommended by the consultation with physicianStorage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.120.00/=
Nipro Seas Syp 100 ml
Nipro Seas Syp 100 mlDescription:Nipro Seas is a multivitamin syrup with cod-liver oil. It contains 8 vitamins and fatty acid (known as cod-liver oil). This combination gives extra protection to children and gives some beneficial effect like:-Helps to stimulate appetite and improve digestion-Promotes healthy hair, skin & nails-Helps in good vision, strong bones & healthy teeth-Increases the resistance against cough, cold, chest and bronchial troubles-Helps to maintain healthy muscles and nervous system-Helps to optimize brain developmentCod-liver oil is composed of vitamin A, D, EPA and DHA. Both EPA & DHA are omega-3 fatty acids. These omega-3 fatty acids keep blood triglycerides in check (high triglycerides are generally linked with increased risk of heart diseases) and may inhibit the progression of atherosclerosis. They also have anti-inflammatory activity; as a result they are also helpful in Crohn's disease and rheumatoid arthritis. It has been also found that omega- 3 fatty acids are needed for prostaglandin formation. Probably as a result of their effect on prostaglandin they are responsible for blood vessel dilation. A double blind trial found that omega- 3 fatty acids helped to treat patient with Raynaud's disease. It has been also found that EPA & DHA have some preventive role in cancer and prevent cardiac arrhythmia.Indication-It is indicated for growing children. It helps in development and proper functioning of their vital organs.-It helps to prevent vitamin deficiency and restore lost vitality after illness, in case of lack of appetite or tiredness of growing children.-It also increases immunity and helps to maintain healthy skin, hair, nail, teeth, bone, eye and nervous system.-In adults it helps to treat and prevent chronic diseases like heart diseases, rheumatoid arthritis, COPD, cancer etc.-In pregnant and nursing mothers it helps in proper development of the baby.Dosage & AdministrationCategoryAgeDoses Children1-12 Months2.5 ml (½ Teaspoonfuls) daily1-4 Years5 ml (1 Teaspoonfuls) daily4 years up7.5 ml (1½ Teaspoonfuls) dailyAdult10 ml (2 Teaspoonfuls) dailyContraindicationThis product is contraindicated in patients with a known hypersensitivity to any of the ingredients.PrecautionThis medicine may accumulate in the body, which may cause danger. So, over dose is prohibited or the physicians should adjust doses.Side EffectsGenerally well tolerated. However, a few allergic reactions may be seen.Drug InteractionSome drug interaction may occur with- Erythromycin, Conjugated estrogens, Sodium bicarbonate, Chloramphenicol etc.Pregnancy & LactationShould be taken on physicians adviceStorage Conditionkeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.80.24/=
Pansos 40 mg Tablet, 1 strip
Pansos 40 mg Tablet, 1 stripDescription:Pansos (Pantoprazole) is a proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus. The binding to the H+/K+ATPase results in a duration of acid antisecretory effect that persists longer than 24 hours.IndicationPansos (Pantoprazole) is indicated where suppression of acid secretion has therapeutic benefit ; i.e1. Peptic ulcer diseases2. Gastroesophageal reflux diseases3. Ulcer, induced by non-steroidal anti-inflammatory drugs (NSAIDs)4. Eradication of Helicobacter pylori (in combination with antibiotics)5. Zollinger-Ellison SyndromeDosage & AdministrationBenign gastric ulcer : 40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed.Gastro-esophageal reflux disease : 20-40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed; maintenance dose is 20 mg daily, which may be increased to 40 mg daily.Duodenal ulcer : 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed.Duodenal ulcer associated with Helicobacter pylori : Pantoprazole is recommended at a dose of 40 mg twice daily in association with antimicrobial agents as detailed below : Amoxycillin 1 g and Clarithromycin 500 mg both twice daily for one week, or Clarithromycin 250 mg and Metronidazole 400 mg both twice daily for one week.Prophylaxis of NSAID-associated gastric or duodenal ulcer : 20 mg daily for those require long-term NSAID treatment.Zollinger-Ellison Syndrome : Initially 80 mg once daily adjusted according to response (elderly max. 40 mg daily); daily doses above 80 mg given in 2 divided doses.ContraindicationPantoprazole is contraindicated in patients with known hypersensitivity to any of the components of the formulation.PrecautionPatients should be cautioned that Pantoprazole tablet should not be split, chewed or crushed. Long-term therapy of Pantoprazole may lead to malabsorption of cyanocobalamin (Vitamin B12) or may increase the risk of osteoporosis related disorders.Side EffectsPantoprazole is well tolerated in both short-term and long-term treatment. Headache and diarrhea are the common side effects and rarely included side effects are abdominal pain, flatulence, rash, insomnia and hyperglycemia.Drug InteractionNo significant drug interactions have been observed in clinical studies.Pregnancy & LactationUS FDA Pregnancy Category of Pantoprazole is B. There are, however, no adequate and well-controlled studies in pregnant woman. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Pantoprazole has been shown to be excreted in human milk. So, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of the drug to the mother.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.50.20/=
Prokinet 10 mg Tablet, 1 strip
Prokinet 10 mg Tablet, 1 stripDescription:Prokinet(Domperidone) is a dopamine receptor antagonist. It gives gastroprokinetic action by blocking dopamine receptors located in the chemoreceptor trigger zone (CTZ) and stomach. Due to its weak penetration across the blood-brain barrier, it has almost no effect on the dopaminergic receptors in the brain, therefore excluding psychotropic and neurologic side effects.IndicationIt is used in the following indications:1. Stimulation of gut motility in non-ulcer dyspepsia, gastro-esophageal reflux disease, reflux esophagitis, diabetic gastroparesis & functional dyspepsia.2. Speeding barium transit in follow through radiological studies.3. Prevention and symptomatic relief of acute nausea and vomiting due to cytotoxic therapy, anti-parkinsonism therapy, radio therapy or migraine.Dosage & AdministrationAdults : 10 - 20 mg every 4 - 8 hours daily.Children : 0.2 - 0.4 mg/kg every 4 - 8 hours daily. For acute nausea and vomiting, maximum period of treatment is 12 weeks. It should be taken 15 - 30 minutes before a meal.ContraindicationIt is contraindicated in patients with known hypersensitivity to Domperidone or any components of the preparation. Domperidone should not be used whenever gastro-intestinal stimulation might be dangerous (i.e., gastro-intestinal hemorrhage, mechanical obstruction or perforation). It is also contraindicated in prolactinoma.PrecautionIt should be used with absolute caution in case of children because there may be increased risk of extra-pyramidal reactions. Since Domperidone is highly metabolized in liver, it should be used with caution in patient with hepatic impairment.Side EffectsIt may produce hyperprolactinemia (1.3%). This may result in galactorrhea, breast enlargement & soreness and reduced libido. Dry mouth (1.9%), thirst, headache (1.2%), nervousness, drowsiness (0.4%), diarrhea (0.2%), skin rash and itching (0.1%) may occur during treatment with Domperidone. Extra-pyramidal reactions are seen in 0.05% of patients in clinical studies.Drug InteractionThe action of Domperidone on gastro-intestinal function may be antagonized by antimuscarinics and opoid analgesics. Care should be exercised when Domperidone is administered in combination with MAO (monoamine oxidase) inhibitors.Pregnancy & LactationThe safety of use of Domperidone has not been proven duing pregnancy; it is therefore not recommended during pregnancy. Animal studies have not demonstrated teratogenic effects on the fetus. Domperidone may precipitate galactorrhea and improve post-natal lactation. It is secreted in breast milk in very small quantities which is insufficient to be considered harmful.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.20.20/=
RABLET 20 Tab
RABLET 20 TabDescription:Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, Rabeprazole has been characterized as a gastric proton-pump inhibitor.Dosage & Administration1) Duodenal ulcer: Rablet 20 mg tablet in the morning is indicated for 4 weeks treatment in the healing and symptomatic relief of duodenal ulcer. Most patients heal within 4 weeks.2) Healing of erosive or ulcerative Gastroesophageal Reflux Disease (GERD): Rablet 20 mg daily in the morning for 4 to 8 weeks. Those patients who have not healed after 8 weeks of treatment, an additional 8-week course of Rablet may be considered.3) Treatment of symptomatic GERD: The recommended adult oral dose of Rablet is 20 mg once daily in the morning for 4 weeks. If symptoms do not resolve completely after 4 weeks, an additional course of treatment may be considered.4) Zollinger-Ellison Syndrome: The recommended adult oral starting dose is 60 mg once a day. Doses should be adjusted according to individual patient needs and should continue for as long as clinically indicated. Some patients may require divided doses. Doses up to 100 mg once daily and 60 mg twice daily have been administered.5) Maintenance of healing of erosive or ulcerative GERD: Rablet is indicated for maintaining healing and reduction in relapse rates of heartburn symptoms in patients with erosive or ulcerative GERD maintenance. Controlled studies do not extend beyond 12 months.ContraindicationRabeprazole is contraindicated in patients with known hypersensitivity to Rabeprazole, other PPIs or to any component of the formulation.PrecautionRablet tablets should not be splited, chewed or crushed.Side EffectsIn general, Rabeprazole is well-tolerated in both short-term and long-term studies. Rabeprazole may sometimes cause headache, diarrhoea, abdominal pain, vomiting, constipation, dry mouth, increased or decreased appetite, muscle pain, drowsiness, dizziness.Drug InteractionRabeprazole is metabolized by the cytochrome P-450 (CYP-450) enzyme system. Studies in healthy subjects have shown that Rabeprazole does not have clinically significant interactions with other drugs metabolized by the CYP-450 system, such as warfarin and theophylline given as single oral doses, diazepam as a single intravenous dose, and phenytoin given as a single intravenous dose.OverdoseThere is no experience with large overdoses with Rabeprazole. The maximum reported overdose is 80 mg. There are no clinical signs or symptoms associated with any reported overdose. Patients with Zollinger-Ellison syndrome have been treated with up to 120 mg Rabeprazole once daily. No specific antidote for Rabeprazole is known.Pregnancy & LactationUS FDA pregnancy category C. Studies have been performed in animals and have revealed no evidence of impaired fertility or harm to the fetus due to Rabeprazole. There are however, no adequate and well-controlled studies in pregnant women. Rabeprazole is likely to be excreted in human milk, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.5.00/=
Rupatid 10 Tab, 1 strip
Rupatid 10 Tab, 1 stripDescription:Rupatadine is a long-acting, non-sedative antagonist of histamine H1-receptors. It also, antagonizes the platelet-activating factor (PAF). Both histamine and PAF causes bronchoconstriction and lead to an increase in the vascular permeability, acting as a mediator in the inflammatory process. This double mechanism of action gives Rupatadine a major clinical efficacy regarding agents that show an isolated antihistamine action. Rupatadine possesses other anti-allergic properties such as the inhibition of the degranulation of mast cells induced by immunological and non-immunological stimuli, and inhibition of the release of cytokines, particularly of the TNFa in human mast cells and monocytes.IndicationRupatadine is indicated for the symptomatic treatment of allergic rhinitis and urticaria.Dosage & AdministrationAdults and adolescents (above 12 years)- The recommended dosage is 10 mg (one tablet) once daily, with or without food.ContraindicationHypersensitivity to Rupatadine or to any of the excipients.PrecautionAdministration of a dose of 10 mg daily of Rupatadine has not shown significant effects on the function of the central nervous system as seen in specific studies done for psychomotor function. Nevetheless, the patient should take precaution in driving or managing machines. The administration of rupatadine with grape fruit juice is not recommended.Side EffectsThe most common undesirable effects occurs somnolence, headache and fatigue. Other common undesirable effects include dizziness, asthenia and increase appetite.Drug InteractionCYP3A4 inhibitors like Erythromycin & Ketoconazole inhibits both the presystemic and systemic metabolism of Rupatadine. Due to this potential interaction, it is not recommended to use Rupatadine in combination with Ketoconazole, macrolides or any other inhibitors of CYP3A4. Co administration of Rupatadine and CNS depressants or alcohol may increase CNS depressant effect.Pregnancy & LactationPregnancy & Lactation: There is no clinical data available on the exposure of Rupatadine during pregnancy. Pregnant women should therefore not use Rupatadine, unless the potential benefit outweighs the potential risk for the infant. No information is available, whether Rupatadine is excreted in the mothers milk. Therefore, it should not be used during lactation, unless the potential benefits for the mother justify the potential risk to the infant.Elderly: Rupatadine should be used with caution in elderly. No information is available that indicates the requirement of any dose adjustment in this population.Children: Neither the safety nor the efficacy of Rupatadine has been established in patients less than 12 years of age.Patients with renal or hepatic insufficiency: Use of Rupatadine is not recommended in patients with renal or hepatic insufficiency. As no relevant clinical data is available.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children..
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Ex Tax: Tk.100.00/=
Starcal D Forte Tab, 1 strip
Starcal D Forte Tab, 1 stripDescription:Starcal D is the preparation of Calcium Carbonate and Vitamin D3 (Cholecalciferol). Calcium is necessary for many normal functions of our body, especially bone formation and maintenance. Vitamin D3 helps for the absorption & reabsorption of Calcium. Vitamin D3 also stimulates bone formation. Clinical studies showed that Calcium and Vitamin D3 all together helps in bone growth, and in prevention of osteoporosis & bone fracture.IndicationThis combination is used for treatment of osteoporosis, osteomalacia, rickets, tetany and in parathyroid disease. Calcium supplements are often used to ensure adequate dietary intake in conditions such as pregnancy & lactation, osteogenesis and tooth formation (adjunct with definite treatment) and therapy with anti-seizure medications. It is also used as routine supplement and phosphate binder in chronic renal failure.Dosage & Administration2 tablets daily or 1 tablet twice daily. It is best taken with or just after a meal to improve absorption.ContraindicationIt is contraindicated in case of hypercalcaemia, hyperthyroidism, renal calculi & nephrolithiasis and Zollinger-Ellison Syndrome.PrecautionIf there is any pre-existing heart disease or kidney disease, precautions should be taken.Side EffectsIt is generally well tolerated. If there is experience like nausea, vomiting, stomach cramps, dry mouth, increased thirst, increased urination while taking, noticed to physicians. Constipation may occur.Drug InteractionIt has possible interaction with calcium, aluminium or magnesium containing antacids & other calcium supplements, calcitriol & other vitamin D3 supplements; digoxin, tetracycline, doxycycline, minocycline or oxytetracycline.OverdoseSymptoms of overdosage may include nausea and vomiting, severe drowsiness, dry mouth, loss of appetite, metallic taste, stomach cramps, diarrhea, headache, constipation.Pregnancy & LactationThis combination should be used as directed by physician during pregnancy or while breast-feeding.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.120.30/=
Starcal D Tab, 1 strip
Starcal D Tab, 1 stripDescription:Starcal D is the preparation of Calcium Carbonate and Vitamin D3 (Cholecalciferol). Calcium is necessary for many normal functions of our body, especially bone formation and maintenance. Vitamin D3 helps for the absorption & reabsorption of Calcium. Vitamin D3 also stimulates bone formation. Clinical studies showed that Calcium and Vitamin D3 all together helps in bone growth, and in prevention of osteoporosis & bone fracture.IndicationThis combination is used for treatment of osteoporosis, osteomalacia, rickets, tetany and in parathyroid disease. Calcium supplements are often used to ensure adequate dietary intake in conditions such as pregnancy & lactation, osteogenesis and tooth formation (adjunct with definite treatment) and therapy with anti-seizure medications. It is also used as routine supplement and phosphate binder in chronic renal failure.Dosage & Administration2 tablets daily or 1 tablet twice daily. It is best taken with or just after a meal to improve absorption.ContraindicationIt is contraindicated in case of hypercalcaemia, hyperthyroidism, renal calculi & nephrolithiasis and Zollinger-Ellison Syndrome.PrecautionIf there is any pre-existing heart disease or kidney disease, precautions should be taken.Side EffectsIt is generally well tolerated. If there is experience like nausea, vomiting, stomach cramps, dry mouth, increased thirst, increased urination while taking, noticed to physicians. Constipation may occur.Drug InteractionIt has possible interaction with calcium, aluminium or magnesium containing antacids & other calcium supplements, calcitriol & other vitamin D3 supplements; digoxin, tetracycline, doxycycline, minocycline or oxytetracycline.OverdoseSymptoms of overdosage may include nausea and vomiting, severe drowsiness, dry mouth, loss of appetite, metallic taste, stomach cramps, diarrhea, headache, constipation.Pregnancy & LactationThis combination should be used as directed by physician during pregnancy or while breast-feeding.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.105.00/=
Tamino Plus 500 mg+65 mg Tablet, 1 strip
Tamino Plus 500 mg+65 mg Tablet, 1 stripDescription:Tamino Plus, is a combination of Paracetamol and Caffeine. Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. Caffeine is an alkaloid which is a theophylline-like xanthine derivative. By intermolecular association with Paracetamol, Caffeine increases the solubility and transmembrane permeation of Paracetamol. In addition, Caffeine increases the pain threshold and tolerance of pain. Caffeine has also an intrinsic power to raise vessel tone in the brain, which provides another benefit to treat migraine and headache.IndicationIt is indicated for the relief of fever, migraine and headache, common cold and flu, sore throat, earache, toothache, backache, rheumatic and muscular pain, neuralgia and menstrual pain.Dosage & AdministrationIt is used for adults and adolescents over 12 years of age as 1-2 tablets in every 4-6 hours as needed. Maximum dose is 8 tablets in 24 hours. It is not recommended for children under 12 years of age.ContraindicationTamino Plus is contraindicated in patients with known hypersensitivity to Paracetamol, Caffeine or any other components of it.PrecautionIt should be used with caution in severe liver or kidney damage. Do not take other Paracetamol containing medications at the same time. Avoid drinking too much coffee or tea when taking this tablet.Side EffectsIn recommended doses, it is usually free from side effects. However, skin reactions such as urticaria have been reported rarely.Drug InteractionIt may interact with anticoagulant agents on prothrombin time. The liver effects of it may be increased by the concomitant use of alcohol certain drugs which enhance the metabolism of Paracetamol in the liver (i.e. barbiturates, tricyclic antidepressants).Pregnancy & LactationAlthough there is epidemiological evidence of the safety of Paracetamol in pregnancy and lactation, medical advice should be sought before using this product.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.15.10/=
V3N Tab, 1 Strip
V3N Tab, 1 StripDescription:V3N is a combined preparation of Vitamin B1 (Thiamine Mononitrate), Vitamin B6 (Pyridoxine Hydrochloride) and Vitamin B12 (Cyanocobalamin). These vitamins play an essential role as co-enzyme in the metabolism of nervous system. supports the regeneration of nerve fibers and myelin sheath by activation of the nerve cell metabolism and the natural repair mechanism.IndicationChronic pains like sciatica, lumbago, trigeminal neuralgia, facial paralysis, optic neuritis as well as neuropathy & cardiac complications. Besides these, this combination may be used in the deficiency of these vitamins.Dosage & Administration1 to 3 tablets per day or as directed by the physician.ContraindicationIt should not be used in patients with known hypersensitivity to Thiamine, Cobalt or any other component of these preparations.PrecautionIt should be avoided in case of hypersensitivity to Thiamine, Cobalt or any other component of these preparations. Cyanocobalamin should not be given before a diagnosis has been fully established because of the masking symptoms of subacute degeneration of the spinal cord.Side EffectsVery rarely hypersensitive reaction and sensitivity disturbance may occur.Drug InteractionVitamin B6 (Pyridoxine Hydrochloride) reduces therapeutic effect of Levodopa but it does not occur if a dopa decarboxylase inhibitor is also given. Neomycin, Chloramphenicol, Aminosalisylic acid & H2 receptor antagonist may reduce Vitamin B12 absorption.Pregnancy & LactationNo risks have become known associated with the use of during pregnancy at the recommended dosage. Vitamin B1, B6 & B12 are secreted into the breast milk but risks of overdose for the infant are not known.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.80.00/=
Visnil 50 mg Tablet, 1 strip
Visnil 50 mg Tablet, 1 stripDescription:Visnil (Tiemonium Methylsulphate) is an antispasmodic drug that reduces muscles spasm of the intestine, biliary system, bladder and uterus.IndicationVisnil (Tiemonium Methylsulphate) is used in symptomatic treatment of pain related to functional disorders of the digestive tract and biliary system. It is also indicated for the treatment of spasm and pain in urological and gynaecological diseases.Dosage & AdministrationAdult: usual dose is 2-6 tablets or 3-9 teaspoonfuls syrup daily in divided doses.Children: 3 ml/kg or 6 mg/kg body weight daily in divided doses.ContraindicationIt should not be used in urethroprostatic disorder involving a risk of urine retension. It is contraindicated in patient with having risk of angle closure glaucoma.PrecautionCaution should be taken during treatment of patients with disorders of the prostate. Caution should also be taken in case of chronic bronchitis, coronary insufficiency, ambient hyperthermia, renal & hepatic insufficiency. The risks of visual disturbances can make it dangerous to drive or use machines.Side EffectsTiemonium Methylsulphate may have the risk of hypotension & tachycardia in certain individuals.Pregnancy & LactationThe results of animal studies of Tiemonium Methylsulphate did not reveal any teratogenic effects; no deformities have been reported up till now with normal use. In absence of sufficient data, prudence should be the rule for nursing mothers although no problems have been reported with normal use.Storage ConditionKeep in dry place and away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.40.10/=
Adarbi 80 mg Tablet, 1 Strip
Adarbi 80 mg Tablet, 1 StripDescription:Adarbi (Azilsartan Medoxomil), a prodrug, is hydrolyzed to Azilsartan in the gastrointestinal tract during absorption. Azilsartan is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan blocks the vasoconstrictor and aldosterone secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland.IndicationAdarbi (Azilsartan Medoxomil) is indicated for the treatment of hypertension to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily stroke and myocardial infarction. Adarbi (Azilsartan Medoxomil) may be used either alone or in combination with other antihypertensive agents.Dosage & AdministrationThe recommended dose in adults is 80 mg taken orally once daily. Consider a Starting dose of 40 mg for patients who are treated with high doses of diuretics. If blood pressure is not controlled with Adarbi alone, additional blood pressure reduction can be ahieved by taking Edarbi with other antihypertensive agents.ContraindicationIt is contraindicated to co-administer Aliskiren with Azilsartan in patients with Diabetes.PrecautionUse of Azilsartan Medoxomil during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. In patients who are intravascularly volume-depleted (e.g., those treated with high-dose diuretics), symptomatic hypotension may occur. Changes in renal function including renal failure has been reported in renal impaired patient.Side EffectsThe most common adverse reaction in adults is diarrhea. The other side effects are nausea, asthenia, fatigue, muscle spasm, dizziness and cough.Drug InteractionNo drug interactions have been observed in studies of Azilsartan Medoxomil or Azilsartan given with amlodipine, antacids, chlorthalidone, digoxin, fluconazole, glyburide, ketoconazole, metformin, pioglitazone and warfarin. The antihypertensive effect of Azilsartan may be attenuated by the non-steroidal anti-inflammatory drugs including selective COX-2 inhibitors. Dual blockade of the RAS with angiotensin receptor blockers, ACE inhibitors or aliskiren is associated with increased risks of hypotension, hyperkalemia and changes in renal function.Storage Conditionkeep in a dry place away from light and heat. Keep out of the reach of children...
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Ex Tax: Tk.220.00/=
Avamist 120 metered Nasal Spray
Avamist 120 metered Nasal SprayDescription:Fluticasone Furoate is a synthetic trifluorinated corticosteroid with potent anti-inflammatory activity. Like other corticosteroids, Fluticasone Furoate is found to have a wide range of actions on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, cytokines) involved in inflammation. Intranasal administration of Fluticasone Furoate significantly improves nasal symptoms (comprising rhinorrhoea, nasal congestion, sneezing and nasal itching) and ocular symptoms (comprising itching/burning, tearing/watering and redness of the eyes). Efficacy is maintained over the full 24-hours dosing period with once daily administration.IndicationAvamist (Fluticasone Furoate) nasal spray is indicated for the treatment of the symptoms of seasonal and perennial allergic rhinitis in adults & children aged 6 years and older.Dosage & AdministrationAvamist nasal spray is recommended for intranasal use only.Adults and adolescents aged 12 years and older: The recommended starting dose is 2 sprays in each nostril once daily. When maximum benefit is achieved with controlled symptoms then only 1 spray in each nostril once daily may be used to reduce possible side effects.Children aged 6 to 11 years: The recommended starting dose is 1 spray in each nostril once daily.How to Use: Prime Avamist nasal spray before using for the first time by shaking the contents well and releasing 6 sprays into the air away from the face. When Avamist nasal spray has not been used for more than 30 days or if the cap has been left off the bottle for 5 days or longer, prime the pump again until a fine mist appears. ContraindicationIt is contraindicated in patients with hypersensitivity to Fluticasone Furoate or any of its ingredients.PrecautionRare incidence of nasal septum perforation, cataracts, glaucoma and impaired wound healing has been reported following the intranasal application of Fluticasone Furoate. Monitor patients closely with a change in vision or with a history of increased intraocular pressure, glaucoma or cataract, tuberculosis, ocular herpes simplex, chickenpox and measles and also for signs of adverse effects on the nasal mucosa. Avoid use in patients with recent nasal ulcers, nasal surgery, or nasal trauma. Use Avamist nasal spray with caution in patients with severe hepatic impairment.Side EffectsAs Fluticasone Furoate nasal spray is less absorbed in the rest of the body, it results in fewer side effects. Most common side effects are headache, epitaxis, Candida albicans infection, pharyngolaryngeal pain, nasal ulceration, back pain, pyrexia and cough.Drug InteractionPotent inhibitors of cytochrome P450 3A4 (CYP3A4) may increase exposure to Fluticasone Furoate. Coadministration of Ritonavir is not recommended. Use caution with coadministration of other potent CYP3A4 inhibitors, such as Ketoconazole.OverdoseChronic overdosage may result in signs/symptoms of hypercorticism. There are no data on the effects of acute or chronic overdosage with Avamist nasal spray. Because of low systemic bioavailability and an absence of acute drug-related systemic findings in clinical studies [with dosages up to 440 mcg/day for 2 weeks (4 times the maximum recommended daily dose)], overdose is unlikely to require any therapy other than observation.Pregnancy & LactationThere are no adequate and well-controlled studies in pregnant women. Avamist nasal spray should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Fluticasone Furoate is excreted in human breast milk. However, other corticosteroids have been detected in human milk. So caution should be exercised when Fluticasone Furoate nasal spray is administered to a nursing woman.USE IN CHILDEREN AND ADOLESCENTS:The safety and effectiveness of Avamist nasal spray in children younger than 6 years have not been established. Controlled clinical trials have shown that intranasal corticosteroids may cause a reduction in growth velocity in pediatric patients. The potential for Fluticasone Furoate to cause growth suppression in susceptible patients or when given at higher than recommended dosages cannot be ruled out.Storage ConditionKeep below 30o C temperature in a dry place, protected from light. Do not refrigerate or freeze. Keep out of the reach of children...
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Ex Tax: Tk.250.00/=
Bactropen 10 gm Ointment
Bactropen 10 gm OintmentDescription:Mupirocin is a naturally occurring antibiotic. This antibacterial agent is produced by fermentation using the organism Pseudomonas fluorescens. It is active against a wide range of bacteria (e.g. Staphylococcus aureus including methicillin-resistant strains and Streptococcus pyogenes) those responsible for the majority of skin infections. It is also active against gram-negative pathogens, such as Escherichia coli and Haemophilus influenzae. Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase.IndicationBactropen ointment is indicated for the topical treatment of impetigo (skin diseases) due to Staphylococcus aureus and Streptococcus pyogenes. It is also indicated in folliculitis, furunculosis.Dosage & AdministrationA small amount of Bactropen ointment should be applied to the affected area 3 times daily for up to 10 days.ContraindicationThe drug is contraindicated in individuals with a history of hypersensitivity reactions to Mupirocin or any of the components of the preparation.PrecautionBactropen ointment is not for ophthalmic or intra-nasal use. As with other antibacterial products, prolonged use may result in overgrowth of non-susceptible organisms, including fungi. When Bactropen is used on the face care should be taken to avoid the eyes. This is not suitable in conjunction with cannulae and at the site of central venous cannulation. In the event of a sensitization or severe local irritation from Bactropen ointment, usage should be discontinued and appropriate alternative therapy for the infection instituted. Mixing of Mupirocin ointment with other preparations causes risk of dilution, resulting in a reduction of the antibacterial activity and potential loss of stability of the Mupirocin in the ointment.Side EffectsReported side effects are burning, stinging or pain, itching and some patient may be suffered rash, nausea, erythema, dry skin, tenderness, swelling, contact dermatitis and increased exudate.Drug InteractionNo drug interaction has been identified with Mupirocin ointment.OverdoseThere is currently limited data with overdose of Mupirocin ointment. In the event of overdose, the patient should be treated supportively with appropriate monitoring as necessary.Pregnancy & LactationReproduction studies on Mupirocin ointment in animals have revealed no evidence of harm to the foetus. As there is no clinical experience on it’s use during pregnancy, Mupirocin ointment should only be used in pregnancy when the potential benefits outweigh the possible risks of treatment.It is unknown whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Mupirocin ointment is administered to a nursing woman.USE IN CHILDREN & ADOLESCENTSThe safety and effectiveness of Mupirocin ointment have been established in the age range of 2 months to 16 years.Storage ConditionKeep below 25o C temperature, protected from light and moisture. Do not keep in freeze. Keep out of the reach of children...
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Ex Tax: Tk.140.00/=
Carceva 75 mg Tablet, 1 Strip
Carceva 75 mg Tablet, 1 StripDescription:Clopidogrel is a prodrug. It inhibits platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets. Dose-dependent inhibition of platelet aggregation can be seen 2 hours after single oral doses. Repeated doses of 75 mg per day inhibit ADP-induced platelet aggregation on the first day, and inhibition reaches steady state between Day 3 and Day 7.CompositionEach film coated tablet contains Clopidogrel Hydrogen Sulfate BP equivalent to Clopidogrel 75 mg.IndicationAcute Coronary Syndrome (ACS):It is indicated to reduce the rate of myocardial infarction (MI) and stroke in patients with non-ST-segment elevation ACS [unstable angina (UA)/non-ST-elevation myocardial infarction (NSTEMI)]. It is indicated to reduce the rate of myocardial infarction and stroke in patients with acute ST-elevation myocardial infarction (STEMI).Recent MI, recent Stroke, or established Peripheral Arterial Disease:In patients with established peripheral arterial disease or with a history of recent myocardial infarction (MI) or recent stroke it is indicated to reduce the rate of MI and stroke.Dosage & AdministrationAcute Coronary Syndrome:In patients who need an antiplatelet effect within hours, initiate clopidogrel with a single 300 mg (4 tablets) oral loading dose and then continue at 75 mg once daily. Initiating it without a loading dose will delay establishment of an antiplatelet effect by several days.Recent MI, Recent Stroke, or Established Peripheral Arterial Disease:75 mg once daily orally without a loading dose.It is given orally with or without food.ContraindicationClopidogrel is contraindicated in the following conditions:* Hypersensitivity to the drug substance or any component of the product.* Active pathological bleeding such as peptic ulcer or intracranial hemorrhage.PrecautionAs it is a prodrug, so metabolism to its active metabolite is impaired by genetic variations in CYP2C19 (poor metabolizer) and by the drugs that inhibit CYP2C19 such as Omeprazole and Esomeprazole. Concomitant use with these drugs and in CYP2C19 poor metaboliser may reduce the antiplatelet activity of Clopidogrel.* As it inhibits platelet aggregation for the lifetime of the platelet (7-10 days), risk of bleeding may increase. To restore hemostasis, platelet transfusions within 4 hours of the loading dose or 2 hours of the maintenance dose may be less effective.* Discontinuation of Clopidogrel increases the risk of cardiovascular events. Discontinue 5 days prior to elective surgery that has a major risk of bleeding. Resume Clopidogrel as soon as hemostasis is achieved.* Thrombotic Thrombocytopenic Purpura (TTP) has been reported that requires urgent treatment including plasmapheresis (plasma exchange).*Hypersensitivity including rash, angioedema or hematologic reaction has been reported in patients receiving clopidogrel or history of hypersensitivity to other thienopyridines.Side EffectsClopidogrel is generally well tolerated drug.Common side effects: Bleeding, Diarrhoea, gastrointestinal discomfort, haemorrhage, Skin reactions.Rare side effects: Acquired haemophilia, anaemia, angioedema, arthralgia, arthritis, bone marrow disorders.Drug Interaction* NSAIDs, warfarin, selective serotonin and serotonin norepinephrine reuptake inhibitors (SSRIs, SNRIs): Increases risk of bleeding* CYP2C19 inhibitors (omeprazole or esomeprazole): Avoid concomitant use of omeprazole or esomeprazole.* Repaglinide (CYP2C8 substrates): Avoid concomitant use of Clopidogrel with Repaglinide as it increases plasma concentrations of RepaglinideOverdoseOverdose following clopidogrel administration may lead to bleeding complications. Based on biological plausibility, platelet transfusion may restore clotting ability.Pregnancy & LactationThere are no adequate and well-controlled studies in pregnant women. It should be used during pregnancy only if clearly needed. It is unknown whether clopidogrel is excreted in human breast milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.USE IN SPECIFIC POPULATIONSafety and effectiveness in pediatric populations have not been established. No dosage adjustment is necessary in elderly patients.Storage ConditionKeep below 30oC temperature in a dry place. Protected from light. Do not freeze. Keep out of the reach of children...
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Ex Tax: Tk.100.00/=
Carceva Plus Tablet,30's pack
Carceva Plus Tablet,30's packDescription:Carceva plus is a fixed dose combination containing Clopidogrel & Aspirin. Clopidogrel is a prodrug. It inhibits platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets. Dose-dependent inhibition of platelet aggregation can be seen at 2 hours after single oral doses. Repeated doses of 75 mg per day inhibit ADP-induced platelet aggregation on the first day, and inhibition reaches steady state between Day 3 and Day 7. Aspirin inhibits platelet aggregation by irreversible inhibition of platelet cyclooxygenase and thus inhibiting the generation of thromboxane A2 a powerful inducer of platelet aggregation and vasoconstriction.CompositionEach film coated tablet contains Clopidogrel Hydrogen Sulfate BP equivalent to Clopidogrel 75 mg and Aspirin BP 75 mg.IndicationAcute Coronary Syndrome (ACS): It is indicated to reduce the rate of Myocardial Infarction (MI) and Stroke in patients with non-ST-segment elevation ACS [unstable angina (UA)/non-ST-elevation Myocardial Infarction (NSTEMI)] and acute ST-segment elevation ACS [ST-elevation Myocardial Infarction (STEMI)].Recent MI, recent Stroke, or established Peripheral Arterial Disease: In patients with established peripheral arterial disease or with a history of recent Myocardial Infarction (MI) or recent Stroke it is indicated to reduce the rate of MI and Stroke.Dosage & AdministrationThe recommended oral dose is one tablet daily.ContraindicationThis combination is contraindicated in the following conditions: Hypersensitivity to the drug substance or any component of the product. Active pathological bleeding such as peptic ulcer or intracranial hemorrhage.PrecautionThis combination may prolongs the bleeding time.Thrombotic thrombocytopenic purpura (TTP): TTP has been reported rarely following use of this combination.Reye's syndrome: Reye's syndrome may develop in individuals who have chicken pox, influenza or flu symptoms. Hypersensitivity including rash, angioedema or hematologic reaction has been reported in patients receiving this combination or history of hypersensitivity to other thienopyridinesSide EffectsThis combination is generally well tolerated.Drug InteractionOral anticoagulants, NSAIDs, Metamizole, SSRIs, CYP2C19 inhibitors increase the risk of bleeding. It shows interaction with Tonofovir, Valproic acid, Varicella vaccine, Acetazolamide and Nicorandil.OverdoseClopidogrel overdose may lead to bleeding complications. Based on biological plausibility, platelet transfusion may restore clotting ability. In moderate aspirin intoxication dizziness, headache, tinnitus, confusion, and gastrointestinal symptoms may occur which can be treated by inducing vomiting followed by gastric lavage if needed. In severe Aspirin intoxication respiratory alkalosis respiratory acidosis, metabolic acidosis, hyperthermia, perspiration, dehydration can occur. It can be treated with haemodialysis and other symptomatic treatment.Pregnancy & LactationThere are no adequate and well-controlled studies in pregnant women. It should be used during first and second trimesters of pregnancy only if clearly needed. It is contraindicated during the third trimester of pregnancy. It is unknown whether Clopidogrel is excreted in human breast milk but Aspirin is known to be excreted in human milk. This Drug should be discontinued during the breast feeding.Storage ConditionKeep in a cool & dry place (below 30oC), protected from light & moisture. Keep out of the reach of children...
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Ex Tax: Tk.330.00/=
D-Star 20000 IU Capsule, 1 Box
D-Star 20000 IU Capsule, 1 BoxDescription:D-Star is a preparation of colecalciferol (Vitamin D3). Vitamin D3 helps for the absorption & reabsorption of calcium & phosphorous. Vitamin D3 is essential for normal bone growth & to maintain bone density. It also reduces the severity of bacterial infection, improves lung function, prevents the risk of cancer (breast, colorectal) & helps to maintain adequate insulin levels for type 2 diabetes patients.IndicationD-Star is indicated in the treatment & prevention of Vitamin D3 deficiency. It is also indicated as an adjunct to specific therapy for osteoporosis in patients with vitamin D3 deficiency.Dosage & AdministrationAdults:Prevention of vitamin D3 deficiency : 20000 IU in every 4 weeks. Higher doses may be required in certain situations.Treatment of vitamin D3 deficiency: 40,000 IU in once weekly for 7 weeks. Doses for maintenance therapy is 1400-2000 IU/day. To confirm the target level of 25-hydroxy D, measurement of it should be determined 3-4 months after initiating the maintenance therapy.Addition to specific therapy for osteoporosis: 20000 IU (1 capsule) once a month.Children (12-18 years):20,000 IU every 6 weeks for vitamin D3 prevention20,000 IU once every 2 weeks for 6 weeks for treatmentContraindicationIt is contraindicated in patients with known hypersensitivity to Vitamin D3.PrecautionIt should be used with caution in patients with impaired renal function.Side EffectsThe general side effects are hypercalcaemia, hypercalciuria, skin rash, pruritus, urticaria, nausea, abdominal pain.Drug InteractionIt interferes with phenytoin, barbiturates, glucocorticoids, certain laxative (such as liquid paraffin), actinomycin and imidazole antifungal agents.Pregnancy & LactationThis high strength formulation is not recommended in pregnancy & lactation.Storage ConditionKeep below 30 degree C temperature, protected from light & moisture. Keep out of the reach of children...
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Ex Tax: Tk.200.00/=
D-Star 40000 IU Capsule, 1 Box
D-Star 40000 IU Capsule, 1 BoxDescription:D-Star is a preparation of colecalciferol (Vitamin D3). Vitamin D3 helps for the absorption & reabsorption of calcium & phosphorous. Vitamin D3 is essential for normal bone growth & to maintain bone density. It also reduces the severity of bacterial infection, improves lung function, prevents the risk of cancer (breast, colorectal) & helps to maintain adequate insulin levels for type 2 diabetes patients.IndicationD-Star is indicated in the treatment & prevention of Vitamin D3 deficiency. It is also indicated as an adjunct to specific therapy for osteoporosis in patients with vitamin D3 deficiency.Dosage & AdministrationAdults:Prevention of vitamin D3 deficiency : 20000 IU in every 4 weeks. Higher doses may be required in certain situations.Treatment of vitamin D3 deficiency: 40,000 IU in once weekly for 7 weeks. Doses for maintenance therapy is 1400-2000 IU/day. To confirm the target level of 25-hydroxy D, measurement of it should be determined 3-4 months after initiating the maintenance therapy.Addition to specific therapy for osteoporosis: 20000 IU (1 capsule) once a month.Children (12-18 years):20,000 IU every 6 weeks for vitamin D3 prevention20,000 IU once every 2 weeks for 6 weeks for treatmentContraindicationIt is contraindicated in patients with known hypersensitivity to Vitamin D3.PrecautionIt should be used with caution in patients with impaired renal function.Side EffectsThe general side effects are hypercalcaemia, hypercalciuria, skin rash, pruritus, urticaria, nausea, abdominal pain.Drug InteractionIt interferes with phenytoin, barbiturates, glucocorticoids, certain laxative (such as liquid paraffin), actinomycin and imidazole antifungal agents.Pregnancy & LactationThis high strength formulation is not recommended in pregnancy & lactation.Storage ConditionKeep below 30 degree C temperature, protected from light & moisture. Keep out of the reach of children...
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Ex Tax: Tk.280.00/=
Defungi 150 mg Capsule,10's pack
Defungi 150 mg Capsule,10's packDescription:Defungi (Fluconazole) is a triazole antifungal agent. It is a potent inhibitor of fungal cytochrome P-450 dependent enzymes. Cytochrome P-450 enzyme system is essential component of fungal cell membrane which is responsible for the synthesis of ergosterol.IndicationIt is indicated for the treatment of vaginal candidiasis, oropharyngeal & esophageal candidiasis and cryptococcal meningitis. It is also effective for the treatment of urinary tract infection caused by candida, peritonitis and systemic candida infections (including candidemia, disseminated candidiasis and pneumonia).Dosage & AdministrationAdult:Vaginal candidiasis: 150 mg as a single dose. Oropharyngeal candidiasis: 200 mg on the first day, followed by 100 mg once daily. Clinical evidence of this infection generally resolves within several days, but treatment should be continued for at least 2 weeks to decrease the likelihood of relapse. Esophageal candidiasis: 200 mg on the first day, followed by 100 mg once daily. Doses up to 400 mg/day may be used. Patients should be treated for a minimum of three weeks and for at least two weeks following resolution of symptoms. Systemic candida infections: Optimal therapeutic dosage and duration of therapy have not been established. Sometimes, doses of up to 400 mg daily have been used. Urinary tract infections caused by candida and peritonitis: 50-200 mg daily have been used. Cryptococcal meningitis: 400 mg on the first day, followed by 200 mg once daily. Prophylaxis in patients undergoing bone marrow transplantation: 400 mg once daily.Child:Doses of 3-6 mg/kg daily have been used. Doses up to 12 mg/kg is recommended.ContraindicationFluconazole should not be used in patients with known hypersensitivity to Fluconazole or to related triazole compounds.PrecautionFluconazole should be administered with caution to patients having proarrhythmic conditions.Side EffectsFluconazole is well tolerated. Most common side effects of using Fluconazole includes nausea, vomiting, abdominal pain, diarrhoea, headache and skin rash.Drug InteractionConcomitant use of cyclosporin or phenytoin with Fluconazole increases the plasma level of cyclosporin or phenytoin. Concomitant use of Fluconazole & warfarin prolongs the prothrombin time. Rifampicin level is decreased when used with Fluconazole.Pregnancy & LactationUS FDA Pregnancy category of Fluconazole is C. So, Fluconazole should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children..
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Ex Tax: Tk.221.60/=
Defungi 50 mg Capsule, 1 Strip
Defungi 50 mg Capsule, 1 StripDescription:Defungi (Fluconazole) is a triazole antifungal agent. It is a potent inhibitor of fungal cytochrome P-450 dependent enzymes. Cytochrome P-450 enzyme system is essential component of fungal cell membrane which is responsible for the synthesis of ergosterol.IndicationIt is indicated for the treatment of vaginal candidiasis, oropharyngeal & esophageal candidiasis and cryptococcal meningitis. It is also effective for the treatment of urinary tract infection caused by candida, peritonitis and systemic candida infections (including candidemia, disseminated candidiasis and pneumonia).Dosage & AdministrationAdult:Vaginal candidiasis: 150 mg as a single dose. Oropharyngeal candidiasis: 200 mg on the first day, followed by 100 mg once daily. Clinical evidence of this infection generally resolves within several days, but treatment should be continued for at least 2 weeks to decrease the likelihood of relapse. Esophageal candidiasis: 200 mg on the first day, followed by 100 mg once daily. Doses up to 400 mg/day may be used. Patients should be treated for a minimum of three weeks and for at least two weeks following resolution of symptoms. Systemic candida infections: Optimal therapeutic dosage and duration of therapy have not been established. Sometimes, doses of up to 400 mg daily have been used. Urinary tract infections caused by candida and peritonitis: 50-200 mg daily have been used. Cryptococcal meningitis: 400 mg on the first day, followed by 200 mg once daily. Prophylaxis in patients undergoing bone marrow transplantation: 400 mg once daily.Child:Doses of 3-6 mg/kg daily have been used. Doses up to 12 mg/kg is recommended.ContraindicationFluconazole should not be used in patients with known hypersensitivity to Fluconazole or to related triazole compounds.PrecautionFluconazole should be administered with caution to patients having proarrhythmic conditions.Side EffectsFluconazole is well tolerated. Most common side effects of using Fluconazole includes nausea, vomiting, abdominal pain, diarrhoea, headache and skin rash.Drug InteractionConcomitant use of cyclosporin or phenytoin with Fluconazole increases the plasma level of cyclosporin or phenytoin. Concomitant use of Fluconazole & warfarin prolongs the prothrombin time. Rifampicin level is decreased when used with Fluconazole.Pregnancy & LactationUS FDA Pregnancy category of Fluconazole is C. So, Fluconazole should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.Storage ConditionKeep in a dry place away from light and heat. Keep out of the reach of children..
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