- Stock: In Stock
- Brand: Healthcare Pharmaceuticals Limited
- Product ID: Insulin Glargine
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Abasaglar KwikPen 100U/ml 3ml — Insulin Glargine Pre-filled Pen | Beximco Pharmaceuticals
| Generic Name | Insulin Glargine 100 Units/ml |
| Device | KwikPen — 3ml Pre-filled Disposable Pen (300 units) |
| Drug Class | Long-Acting Basal Insulin Analogue (Biosimilar) |
| Manufacturer | Beximco Pharmaceuticals Ltd. |
| Route | Subcutaneous Injection Only |
| Prescription Status | Prescription Required |
Overview
Abasaglar KwikPen delivers Insulin Glargine 100U/ml in a convenient pre-filled pen device — the same biosimilar basal insulin as Abasaglar vials, but with the ease of a dial-and-inject pen. The KwikPen allows doses to be dialled in 1-unit increments without the need for syringes, improving accuracy, convenience, and adherence. Each 3ml cartridge provides 300 units of insulin glargine for once-daily subcutaneous injection.
Mechanism of Action
Insulin Glargine forms a subcutaneous depot at physiological pH, releasing monomeric insulin slowly over 24 hours. This provides stable, peakless basal insulin coverage mimicking physiological fasting insulin secretion. It activates insulin receptors to promote cellular glucose uptake, suppress hepatic glucose output, and inhibit lipolysis and ketogenesis.
Indications
- Type 1 Diabetes Mellitus — as the basal component of basal-bolus insulin therapy
- Type 2 Diabetes Mellitus — when oral agents are insufficient for glycaemic control
- Patients preferring pen device over vial and syringe for greater accuracy and convenience
Using the KwikPen
| Step | Action |
|---|---|
| 1 | Attach a new pen needle |
| 2 | Prime the pen: dial 2 units and press button with needle pointing up — confirm insulin droplet |
| 3 | Dial your prescribed dose |
| 4 | Inject subcutaneously (abdomen, thigh, or upper arm) |
| 5 | Hold needle in skin for 6–10 seconds after pressing, then withdraw |
| 6 | Remove and safely dispose of needle after each use |
Dosage
| Patient | Starting Dose | Timing | Titration |
|---|---|---|---|
| Type 2 (insulin-naive) | 0.2 units/kg or 10 units | Once daily (fixed time) | +2 units every 3 days if fasting glucose >5.5 mmol/L |
| Type 1 diabetes | ~30–50% of total daily insulin | Once daily | Physician-guided titration |
Critical Diabetic Patient Instructions
- Hypoglycaemia risk: Always carry fast-acting glucose. Inject at consistent time daily. Never skip meals after injection
- Never share pens: Even with a new needle — risk of infection and blood-borne disease transmission
- Never mix: Do not inject other insulins through the same pen or mix in same injection
- Site rotation: Rotate injection sites within the same body region daily to prevent lipohypertrophy
- Pen storage: Once in use, keep at room temperature below 30°C for up to 28 days — do not refrigerate in-use pen
- Needle disposal: Always use a new needle each injection. Dispose safely in sharps container
- Checking remaining insulin: View through the pen window — do not use if cloudy, coloured, or containing particles
Side Effects
| System | Side Effect | Severity |
|---|---|---|
| Metabolic | Hypoglycaemia — most common; can be severe/nocturnal | Common — Serious |
| Local | Injection site reactions, lipohypertrophy, lipoatrophy | Common — Mild |
| Metabolic | Weight gain | Common — Moderate |
| Systemic | Generalised allergic reaction, anaphylaxis (rare) | Rare — Serious |
Storage
Unopened pens: Refrigerate 2–8°C. Do not freeze. Protect from light.
In-use pen: Store below 30°C away from heat and light. Use within 28 days. Do not refrigerate.
Frequently Asked Questions
Q: What is the difference between the KwikPen and the vial version?
A: The KwikPen is a pre-filled disposable pen device — no syringe needed. Simply attach a pen needle, dial the dose, and inject. The vial requires a separate insulin syringe. Both contain the same insulin glargine 100U/ml.
Q: Can I reuse pen needles?
A: No. Always use a new sterile pen needle for each injection. Reusing needles causes blunting (more painful), risk of infection, and blocked needles.
Q: What happens if I inject too much Abasaglar?
A: Overdose causes hypoglycaemia. Treat mild hypoglycaemia (blood glucose <4 mmol/L) with 15–20g fast-acting glucose. Severe hypoglycaemia (unconscious) requires glucagon injection or IV glucose — call emergency services immediately.
Medical Disclaimer: Abasaglar KwikPen (Insulin Glargine 100U/ml) is a prescription-only medicine. Never share insulin pens. Hypoglycaemia is a serious risk — patients must be trained in recognition and emergency management. Dose must be individually prescribed and monitored. This information is for educational purposes only. Always follow your physician's instructions.
