Adexim Suspension

Adexim Suspension — Composition & Pharmacology

Generic Name: Cefixime Trihydrate (Oral Suspension)
Manufacturer: Beximco Pharmaceuticals Ltd.
Drug Class: Third-Generation Oral Cephalosporin Antibiotic
Dosage Form: Oral Suspension

Adexim Suspension contains Cefixime Trihydrate — a broad-spectrum, third-generation oral cephalosporin antibiotic. The suspension formulation is especially suitable for children and patients who have difficulty swallowing tablets. Cefixime exerts bactericidal activity by inhibiting bacterial cell wall synthesis via binding to penicillin-binding proteins (PBPs).

Indications

Adexim Suspension (Cefixime) is indicated for treatment of infections caused by susceptible organisms:

• Otitis Media (Middle Ear Infection): Especially common indication in paediatric patients
• Pharyngitis & Tonsillitis caused by Streptococcus pyogenes
• Urinary Tract Infections: Uncomplicated UTIs caused by E. coli and Proteus mirabilis
• Respiratory Tract Infections: Acute bronchitis, acute exacerbations of chronic bronchitis
• Typhoid Fever: Uncomplicated typhoid in susceptible cases

Dosage & Administration

Children: 8mg/kg/day as a single dose or divided into two doses every 12 hours. Shake the suspension well before each use. Use the measuring device provided.

Adults (who cannot take tablets): 200–400mg/day as directed by the physician.

Duration: As prescribed. Do not discontinue early even if symptoms resolve.

Administration: May be taken with or without food. Refrigerate after reconstitution and discard after 14 days.

Contraindications & Precautions

• Contraindicated in patients with known hypersensitivity to cefixime, other cephalosporins, or penicillins
• Dose adjustment required in renal impairment (CrCl <60 mL/min)
• Caution in patients with history of GI disease, particularly colitis
• Monitor for superinfection with prolonged use

Side Effects

Common: Diarrhoea, loose stools, nausea, abdominal pain, flatulence. Hypersensitivity reactions (rash, urticaria) may occur rarely. Serious but rare: Clostridioides difficile-associated diarrhoea.

Storage

Store dry powder below 30°C. After reconstitution, store in refrigerator and use within 14 days. Shake well before use. Keep out of reach of children.

Medical Disclaimer: This information is for reference purposes only and is not a substitute for professional medical advice. Cefixime is a prescription antibiotic. Always consult a qualified physician before use. Completing the full prescribed course is essential. Diabetesstore.com.bd strongly recommends obtaining a valid prescription for this medication.