Iventi -D 5 ml Eye drop

Overview

Iventi-D (Moxifloxacin Hydrochloride + Dexamethasone) 0.5%+0.1% Eye Drop is a combination ophthalmic solution manufactured by Square Pharmaceuticals PLC. Each ml contains Moxifloxacin 5 mg (a 4th generation fluoroquinolone antibacterial) and Dexamethasone Phosphate 1 mg (a corticosteroid anti-inflammatory). Iventi-D is indicated for the treatment of bacterial eye infections and for the prevention of inflammation and bacterial infection following ocular surgery (including cataract and LASIK procedures). The dual action of antibiotic and steroid makes it particularly useful in post-surgical ophthalmic care.

Dosage and Administration

Prevention of post-surgical infection and inflammation: Instill 1 drop 4 times daily in the eye to be operated, starting 1 day before surgery and continuing for 15 days after surgery. On the day of cataract surgery: instill immediately after surgery. On the day of LASIK surgery: instill at least 15 minutes after surgery. Treatment of eye infections: Instill 1 drop 4 times daily for up to 7 days. Do not touch the dropper tip to any surface. Use within 28 days of first opening.

Interaction

No specific drug interaction data is available for ophthalmic Moxifloxacin + Dexamethasone combination. Systemic absorption from eye drops is minimal; however, caution is advised when used in patients on systemic corticosteroids or immunosuppressants. Consult your physician before concurrent use with other eye drops.

Contraindications

Iventi-D is contraindicated in: hypersensitivity to quinolones or any component of the formulation; patients with glaucoma or diseases causing corneal or scleral thinning; viral eye infections (herpes simplex keratitis, vaccinia, varicella, other viral corneal/conjunctival disease); mycobacterial or fungal ocular infections.

Side Effects

Moxifloxacin-related: conjunctivitis, decreased visual acuity, dry eye, keratitis, ocular discomfort, hyperemia, pain, subconjunctival hemorrhage, and tearing. Dexamethasone-related: visual field defects, cataract formation, secondary ocular infection (due to immune suppression), and globe perforation (with corneal or scleral thinning). Prolonged steroid use may cause ocular hypertension and glaucoma.

Pregnancy and Lactation

Use during pregnancy only if clearly needed and the potential benefit justifies the risk. Caution is advised in nursing women. Consult a physician before use.

Precautions and Warnings

Discontinue immediately if hypersensitivity to moxifloxacin occurs. Monitor intraocular pressure regularly during prolonged use — corticosteroids may cause ocular hypertension and glaucoma. Avoid in diseases causing corneal or scleral thinning due to risk of perforation. Steroids may mask or worsen existing eye infections. Do not use contact lenses during treatment. Discard 28 days after first opening. Safety in pediatric patients has not been established.

Storage Conditions

Store in a cool place below 30°C, protected from light. Once opened, discard after 28 days. Keep out of the reach of children.

Frequently Asked Questions

Q: What makes Iventi-D different from regular Iventi eye drops?
A: Iventi-D contains two active ingredients — Moxifloxacin (antibiotic) and Dexamethasone (steroid). This combination treats both infection and inflammation simultaneously, making it especially useful after eye surgery or when bacterial infection is accompanied by significant ocular inflammation.

Q: How soon after eye surgery should Iventi-D be started?
A: For surgical prophylaxis, treatment should begin 1 day before surgery and continue for 15 days after. On the day of surgery, instill the drop immediately after cataract surgery, or at least 15 minutes after LASIK surgery.