- Stock: In Stock
- Brand: Beximco Pharmaceutical
- Product ID: Amoxicillin Trihydrate
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Tycil 250mg Capsule — Amoxicillin Trihydrate 250mg | Beximco Pharmaceuticals
| Generic Name | Amoxicillin Trihydrate 250 mg |
| Dosage Form | Capsule |
| Manufacturer | Beximco Pharmaceuticals Ltd. |
| Therapeutic Class | Aminopenicillin — Broad-Spectrum Beta-Lactam Antibiotic |
| Spectrum | Gram-positive and selected Gram-negative bacteria |
| Availability | In Stock — Available Online |
Overview
Tycil 250mg is Beximco's brand of Amoxicillin Trihydrate 250mg, an aminopenicillin antibiotic that is one of the most widely prescribed antibiotics globally and in Bangladesh. Amoxicillin combines the broad-spectrum activity of ampicillin with significantly better oral bioavailability (~93% vs ~40% for ampicillin), enabling effective systemic treatment with oral dosing. It covers common Gram-positive pathogens (Streptococci, Enterococci), selected Gram-negatives (H. influenzae, E. coli), and is the standard first-line antibiotic for uncomplicated respiratory tract, urinary tract, and ear infections. The 250mg capsule is used for mild infections and in smaller adults/children who can swallow capsules.
Tycil Amoxicillin Range
| Product | Strength/Form | Use |
|---|---|---|
| Tycil 250mg Capsule (this) | 250 mg capsule | Adults — mild infections / 3× daily dosing |
| Tycil 500mg Capsule | 500 mg capsule | Adults — standard dose / moderate infections |
| Tycil Suspension 100ml | 125 mg/5 mL | Children — standard suspension |
| Tycil DS Suspension 100ml | 250 mg/5 mL (double strength) | Children — higher weight-based dose |
| Tycil Paediatric Drops 15ml | 100 mg/mL | Infants & small children |
Indications
- Upper Respiratory Tract Infections — pharyngitis (S. pyogenes), tonsillitis, sinusitis
- Lower Respiratory Tract Infections — community-acquired pneumonia (mild, outpatient), acute bronchitis (bacterial)
- Otitis Media (Ear Infection) — H. influenzae, S. pneumoniae, M. catarrhalis
- Urinary Tract Infections (Uncomplicated) — E. coli (susceptible strains), E. faecalis
- Skin & Soft Tissue Infections — impetigo, cellulitis (Streptococcal)
- H. pylori Eradication — part of triple/quadruple regimen with PPI and clarithromycin
- Dental Infections — oral amoxicillin for dental abscess, prophylaxis
- Typhoid — only for susceptible strains (resistance common — confirm sensitivity)
Dosage & Administration
| Indication | Dose | Frequency | Duration |
|---|---|---|---|
| Mild-Moderate Infections (adults) | 250–500 mg | Three times daily (q8h) | 5–10 days |
| Severe Infections (adults) | 500 mg–1g | Three times daily | 10–14 days |
| H. pylori Eradication | 1g (2× 500mg) | Twice daily | 7–14 days (with PPI + clarithromycin) |
| Children (weight-based) | 25–50 mg/kg/day | Divided q8h | 5–10 days |
| Dental Prophylaxis | 2g (8× 250mg) | Single dose 30–60 min pre-procedure | Once |
Can be taken with or without food. Amoxicillin absorption is NOT significantly affected by food (unlike some antibiotics). Take at evenly spaced intervals (every 8 hours). Complete the full course.
Special Note for Diabetic Patients
Amoxicillin is one of the safest antibiotics in diabetic patients. It does not affect blood glucose, has no interaction with common diabetes medications, and is well-tolerated even with renal impairment (reduce dose frequency in severe CKD). Diabetic patients with UTI or respiratory infections can safely take Tycil 250mg under physician guidance.
Drug Interactions
| Drug | Interaction |
|---|---|
| Warfarin | May enhance anticoagulant effect — monitor INR |
| Allopurinol | Increased risk of skin rash — avoid combination if possible |
| Oral contraceptives | May theoretically reduce efficacy — use barrier contraception during antibiotic course |
| Methotrexate | Amoxicillin may increase methotrexate levels — monitor |
Side Effects
- Common: Diarrhoea, nausea, vomiting (GI upset — take with food to minimise)
- Common skin: Maculopapular rash (especially in viral infections like EBV — this is NOT allergy)
- Uncommon: Urticaria (true allergic rash)
- Serious: Anaphylaxis (rare — <0.05%; immediate IM adrenaline required)
- GI: Antibiotic-associated diarrhoea; C. difficile colitis (rare with amoxicillin)
Contraindications
- Documented penicillin allergy (anaphylaxis, urticaria, angioedema)
- Do NOT use for MRSA infections
- Do NOT use empirically for infections in areas with high amoxicillin resistance without sensitivity testing
Storage
- Store below 25°C in a dry place, protected from moisture. Keep out of reach of children.
FAQ
Q1: What is the difference between Tycil 250mg and Tycil 500mg?
Both contain amoxicillin — the 500mg capsule contains double the active ingredient. The 250mg is used for mild infections, children who can swallow capsules (with weight-based dosing), and for lower-dose regimens. The 500mg is the standard adult dose for most moderate infections. Your physician will prescribe the appropriate strength.
Q2: Can I take Tycil with food?
Yes. Amoxicillin can be taken with or without food. Food does not significantly affect its absorption. Taking it with food may help reduce nausea or stomach discomfort.
Q3: I developed a rash while taking Tycil — am I allergic to penicillin?
Not necessarily. Amoxicillin can cause a non-allergic, non-itchy maculopapular rash (measles-like red spots) in patients who have a concurrent viral infection (especially EBV/glandular fever). This rash is NOT a penicillin allergy. A true penicillin allergy causes urticaria (hives) or anaphylaxis. Stop the antibiotic and consult your physician to distinguish between the two — being incorrectly labelled as "penicillin allergic" can limit your antibiotic options for life.
Q4: Is amoxicillin safe during pregnancy?
Yes — amoxicillin is classified as safe for use during pregnancy (Category B) and is one of the preferred antibiotics for UTI and respiratory infections in pregnant women. Always take under physician supervision during pregnancy.
Medical Disclaimer: Educational information only. Always take antibiotics only as prescribed by a licensed physician.
