A-B1 100 mg Tablet, 1 strip

A-B1 100 mg Tablet, 1 strip

DESCRIPTION

A-B1 (Thiamine Hydrochloride) is a water soluble vitamin. It is an organic

molecule which contains a pyrimidine and a thiazole nucleus linked by a

methylene bridge. It occurs as small white hygroscopic crystals or

crystalline powder that usually has a slight characteristic odour. It

functions in the body in the form of coenzyme Thiamine pyrophosphate.

Thiamine pyrophos-phate serves as a coenzyme in carbohydrate

metabolism by decar-boxylation of a-keto acids such as pyruvate and

a-ketoglutarate which leads to the formation of acetyl CoA. Thiamine or

Vitamin B1 also participates in the formation or degradation of a-ketols by

transketolase. Vitamin B1 is essential for metabolism of carbohydrate.

Recommended daily intake of Thiamine is 0.5mg/1000 kcal. Major

symptoms of Thiamine deficiency are related to the nervous system (Dry

beriberi) and to the cardiovascular system (Wet beriberi).

COMPOSITION

Each tablet contains Thiamine Hydrochloride BP 100 mg.

INDICATIONS

Infantile beriberi : Loss of appetite, vomiting, greenish stools, followed by

paroxysmal attacks of muscular rigidity.

Adult beriberi : Dry skin, discomfort, confabulation followed by paralysis.

Wernicke's encephalopathy : Neuropsychiatric disorder may develop in

some cases due to alcohol intake.

Korsakoff's syndrome : Diabetes, cancer and in other cases for example

the patients having nutritional intake parenterally where Vitamin B1 is

absent may arise Vitamin B1 deficiency.

Fatigue, anorexia

Gastrointestinal disturbance

Neurological disorder

Other Vitamin B1 deficiency in case of pregnancy and lactation.

DOSAGE AND ADMINISTRATION

Mild to moderate chronic deficiency : ¼ tablet daily.

Severe deficiency : 2-3 tablets daily.

OR AS DIRECTED BY THE PHYSICIAN.

SIDE EFFECTS

No known side effect have yet been established.

CONTRAINDICATIONS

A-B1 is contraindicated in patients who are hypersensitive to it.

SUPPLY

Each box contains 10 x 10 tablets in blister strip.