A-CALM 50 mg Tablet

A-CALM 50 mg Tablet

DESCRIPTION

Tolperisone hydrochloride is a centrally acting muscle relaxant, which acts on the central nervous system and used mainly for the treatment of elevated muscle tone and tension as well as for certain circulatory problems in the extremities. It reduces experimental hypertonia and decerebration and improves peripheral blood flow. The circulatory effect is supposed to be based on peripheral mechanism and is independent from the cerebral centers of vasoregulation.

COMPOSITION

Each film-coated tablet contains Tolperisone hydrochloride INN 50 mg.

INDICATIONS

Increased tone of skeletal muscles due to organic neurological disorders (e.g. injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis etc.), muscular hypertension, muscular spasm, muscular contraction & rigidity, spinal automatism and discopathy. Obliterate vascular diseases (obliterate arteriosclerosis, diabetic angiopathy, obliterative thromboangitis, raynaud's disease, diffusion scleroderma) and disorders due to injury innervation of the vessels (acrocyanosis, intermittent angioneurotic dysbasia). In individual cases post thrombotic venous and circulation disorders and crural ulcer.

DOSAGE AND ADMINISTRATION

One should follow the doctor's instructions regarding the dosage of Tolperisone hydrochloride. The recommended dose is as followings: Adult: 50-150 mg three times daily according to the individual requirement and tolerance of the patients. Children: (from 6 to 14 years): 2-4 mg/kg/day in three divided doses. Children: (from 3 months to 6 years): 5-10 mg/kg/day in three divided doses.

SIDE EFFECTS

Sometimes muscular weakness, headache, nausea, vomiting, and rarely hypersensitivity reactions.

CONTRAINDICATIONS

Hypersensitivity to Tolperisone, Myasthenia gravis, nursing mother. PRECAUTIONS Incase of children, the prescribed dose and duration of treatment should closely be observed.

USE IN PREGNANCY AND LACTATION

Tolperisone hydrochloride should be used in pregnancy to physician's advice. Tolperisone hydrochloride should not be used during breastfeeding.

DRUG INTERACTION

Concomitant use of methocarbamol with tolperisone hydrochloride has been reported to cause disturbance of visual accommodation.

SUPPLY

Each box contains 5 x 10 tablets in blister strips