- Stock: Out Of Stock
- Brand: Acme Laboratories Limited
- Product ID: Bromhexine Hyrdochloride
100% Secure Payment
bKash | Nagad | Cards via SSLCommerz | COD
Monthly Medicines Available | Free Delivery on Eligible Orders
This Item is for pre order
A-Cold 100 ml Syrup (Bromhexine Hydrochloride) — Product Overview
| Quick Reference | |
|---|---|
| Brand Name | A-Cold Syrup |
| Generic Name | Bromhexine Hydrochloride |
| Drug Class | Mucolytic / Expectorant |
| Manufacturer | ACI Limited, Bangladesh |
| Dosage Form | Oral Syrup |
| Pack Size | 100 ml bottle |
| Storage | Below 30°C, protect from light. Do not refrigerate. |
| Prescription Status | Available without prescription (OTC) |
What is A-Cold Syrup (Bromhexine)?
A-Cold Syrup contains Bromhexine Hydrochloride, a well-established mucolytic (mucus-thinning) agent used to relieve productive coughs associated with chest congestion. Bromhexine breaks down the mucopolysaccharide structure of mucus in the airways, making it thinner and easier to cough up. It is widely used in Bangladesh and globally for acute and chronic respiratory conditions where thick, sticky mucus makes breathing and expectoration difficult.
Mechanism of Action
Bromhexine acts as a mucolytic secretolytic agent. It disrupts the disulphide bonds in the mucopolysaccharide fibres of bronchial mucus, reducing mucus viscosity and increasing mucus fluidity. It also stimulates goblet cells and serous cells in the respiratory mucosa to produce serous (watery) secretions, improving mucociliary clearance. In the liver, bromhexine is metabolised to ambroxol, which is itself an active mucolytic — so some of the therapeutic effect comes from this active metabolite.
Indications — What A-Cold Syrup Treats
A-Cold Syrup is indicated for:
- Acute bronchitis: Productive cough with thick mucus
- Chronic bronchitis: Persistent mucus hypersecretion and impaired expectoration
- Asthma with mucus hypersecretion: As adjunct therapy to loosen secretions
- Pneumonia and lung infections: To aid clearance of secretions
- COPD (Chronic Obstructive Pulmonary Disease): Relief of mucus plugging
- Bronchiectasis: Thinning of copious secretions
- Post-operative care: To prevent mucus accumulation after thoracic surgery
Dosage and Administration
Adults and children over 12 years: 10 ml (approximately 8 mg) three times daily.
Children 5–12 years: 5 ml (approximately 4 mg) three times daily.
Children 2–5 years: 2.5 ml (approximately 2 mg) three times daily.
Administration: Take after meals to reduce risk of nausea. Shake the bottle well before use. Ensure adequate fluid intake (drink plenty of water) while taking this medicine — hydration helps thin mucus and maximises the mucolytic effect.
Contraindications
- Hypersensitivity to bromhexine or any excipient in the formulation
- Severe peptic ulcer disease (use with caution; may worsen symptoms)
Side Effects
Common: Nausea, vomiting, diarrhoea, abdominal discomfort (especially on an empty stomach), mild skin rash.
Uncommon: Headache, dizziness, increased liver enzymes (transient).
Rare: Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) — discontinue immediately if severe rash develops.
GI side effects are significantly reduced by taking the syrup after food.
Drug Interactions
- Antibiotics (amoxicillin, erythromycin, doxycycline): Bromhexine increases penetration of certain antibiotics into lung tissue — a beneficial interaction used therapeutically
- Antitussives (cough suppressants like codeine, dextromethorphan): Avoid combining with cough suppressants — suppressing the cough reflex while thinning mucus can lead to mucus pooling in the airways
- Aspirin: May increase risk of GI irritation
Special Populations
Pregnancy: Avoid in the first trimester. Use in second and third trimester only if clearly necessary and under medical supervision.
Breastfeeding: Not recommended during breastfeeding; small amounts pass into breast milk.
Renal/hepatic impairment: Use with caution; reduce dose or increase dosing interval in severe impairment.
Children under 2 years: Not recommended without specific medical advice.
Frequently Asked Questions (FAQ)
Q: What is A-Cold Syrup used for?
A: A-Cold Syrup (Bromhexine) is a mucolytic used to thin and loosen thick mucus in the airways, making it easier to cough up. It is used for bronchitis, chest colds, asthma, COPD, and other conditions with productive cough and chest congestion.
Q: How long does A-Cold Syrup take to work?
A: Bromhexine typically begins working within 2–3 days of regular use. For optimal mucolytic effect, drink plenty of water throughout the day alongside the medication.
Q: Can I take A-Cold Syrup with antibiotics?
A: Yes — bromhexine is often prescribed alongside antibiotics for respiratory infections. It actually helps antibiotics penetrate lung tissue more effectively, which is a beneficial drug interaction.
Q: Can children use A-Cold Syrup?
A: Yes, A-Cold Syrup is suitable for children aged 2 years and above with appropriate dose adjustment. Children 2–5 years: 2.5 ml three times daily; children 5–12 years: 5 ml three times daily.
Medical Disclaimer
The information provided is for educational purposes only. Always consult a qualified healthcare professional before giving any medication to children or if symptoms worsen or persist beyond 7 days. Do not combine with cough suppressants without medical advice.
