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A-Zyme 325 mg Tablet, 1 strip

A-Zyme in Bangladesh,A-Zyme price , usage of A-Zyme
A-Zyme 325 mg Tablet, 1 strip
Tk35
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A-Zyme 325 mg Tablet, 1 strip

DESCRIPTION

A-Zyme (Pancreatin) is a preparation of Pancreatin, an extract from mammalian pancreas containing enzymes with Amylase, Protease and Lipase activity. It is designed to disintegrate in the alkaline medium of the duodenum where it releases the active enzyme components of Pancreatin (Amylase, Protease and Lipase). Amylase hydrolyzes dietary starch to yield maltose, maltoriose and adextrin. Protease cleaves peptide bonds in the center of proteins and polypeptides and forms amino acids and oligopeptides. Lipase hydrolyzes dietary triglycerides forming two molecules of fatty acid and a molecule of betamonoglyceride. It converts not less than 25 times its weight of starch into soluble carbohydrates and not less than 25 times its weight of casein into proteoses within 5 mins. (equivalent to 150 times in 30 mins).

COMPOSITION

Each enteric-film-coated tablet contains 325 mg of Pancreatin BP that provides not less than the following enzymatic activityAmylase 7800 units Protease 455 units Lipase 6500 units

INDICATIONS

A-Zyme is employed for the treatment of patients with

● Chronic pancreatitis
● Cystic fibrosis/Mucoviscidosis
● Following partial or complete pancreatectomy
● Total gastrectomy
● Steatorrhea
● Somatostatinoma
● Celiac disease and
● Other conditions associated with pancreatic insufficiency.

DOSAGE AND ADMINISTRATION

2-3 tablets to be swallowed whole with little water immediately after or during meal.

OR AS DIRECTED BY THE PHYSICIAN.

SIDE EFFECTS

The most frequent side effects are gastrointestinal including nausea, vomiting and abdominal discomfort. Buccal and perianal soreness may occur, particularly in infants. Hypersensitivity reactions manifested by sneezing, lacrimation or skin rashes have been reported.

CONTRAINDICATIONS

Pancreatin is contraindicated in patients with known hypersensitivity to the drug.

PRECAUTIONS

Patients known to be allergic to animal protein should be treated with caution.

USE IN PREGNANCY AND LACTATION

Pancreatin should be given to a pregnant woman only if clearly needed. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Pancreatin is administered to a nursing mother.

DRUG INTERACTIONS

Alkaline media will rupture the enteric coating. As such to prevent bursting out of the content in the stomach Pancreatin should not be used concurrently with antacid.

OVERDOSAGE

Excessive dosage may produce a laxative effect. Systemic toxicity does not occur. Very high dosage may cause hyperuricaemia and hyperuricosuria.

SUPPLY

Each box contains 10 X 10 tablets in strips.

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