ALMEX 10 ml Oral Suspension

Overview

Almex Oral Suspension 200 mg/5 ml contains Albendazole, manufactured by Square Pharmaceuticals PLC. It is a broad-spectrum benzimidazole anthelmintic suitable for children and patients who require a liquid dosage form.

Indications

Almex is indicated in single and mixed infestations of Hookworm (Ancylostoma, Necator), Roundworm (Ascaris), Threadworm (Enterobius), Whipworm (Trichuris), Strongyloides, Tapeworm, Opisthorchi, and Hydatid disease.

Pharmacology

Albendazole exhibits vermicidal, ovicidal and larvicidal activities. It exerts its anthelmintic effect by blocking glucose uptake in susceptible helminths, depleting their energy until it becomes inadequate for survival. This is linked to inhibition of parasite tubulin polymerization. The principal metabolite, albendazole sulphoxide, has anthelmintic activity with a plasma half-life of about 8.5 hours.

Dosage and Administration

Adults and children over 2 years: 10 ml suspension as a single dose for Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale and Necator americanus. For strongyloidiasis or taeniasis: 10 ml daily for 3 consecutive days. Children 1-2 years: single dose of 5 ml. Children under 1 year: not recommended. In giardiasis: 10 ml once daily for 5 days, or as advised by the physician.

Interaction

No interaction involving Almex, either pharmacodynamic or pharmacokinetic, has been reported.

Contraindications

Not normally used in neonates. Should not be given during pregnancy or to women thought to be pregnant. Dose reduction may be indicated in children weighing less than 10 kg.

Side Effects

Gastrointestinal disturbances, headache, dizziness, changes in liver enzymes, rarely reversible alopecia, rash, fever, and rarely blood disorders including leucopenia and pancytopenia.

Pregnancy and Lactation

US FDA Pregnancy Category C. Should be avoided in pregnancy and lactation unless potential benefits outweigh possible risks to the fetus.

Precautions and Warnings

Blood counts and liver function tests recommended before treatment and twice during each cycle. Exclude pregnancy before starting treatment. Use only under medical supervision for Echinococcosis treatment with regular monitoring.

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.

Frequently Asked Questions

What is Almex Suspension used for?
It is used to treat intestinal worm infestations including roundworm, hookworm, whipworm, threadworm and tapeworm, especially in children.

What is the dose for young children?
Children 1-2 years are typically given a single 5 ml dose; children under 1 year are not recommended Almex unless advised by a physician.

This content is for informational purposes only and does not substitute professional medical advice. Please consult a registered physician before taking any medication.