Amikin 100mg Injection — Amikacin by Beximco Pharmaceuticals

Amikin 100mg Injection — Amikacin | Beximco Pharmaceuticals

Overview

Amikacin 100mg injection for IV/IM use. Broad-spectrum aminoglycoside active against MDR Gram-negative bacteria including Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii. Dose: 15mg/kg once daily. Mandatory therapeutic drug monitoring (TDM) — peak 56–64 mg/L, trough <5 mg/L. Daily renal function monitoring required throughout treatment.

Critical Warnings for Diabetic Patients

• Nephrotoxicity: Diabetic nephropathy at any stage dramatically increases risk — monitor creatinine and eGFR daily
• Ototoxicity: Irreversible sensorineural hearing loss — audiometry baseline for courses >7 days
• Avoid concurrent nephrotoxins: NSAIDs, IV contrast, vancomycin
• Hydrate before dosing: 500mL–1L IV saline pre-infusion significantly reduces nephrotoxicity

Storage

Store at 15–25°C. Do not freeze. Protect from light. Single use.

Medical Disclaimer: Hospital and specialist prescription use only. Mandatory TDM and renal monitoring required. Diabetic patients with CKD face elevated nephrotoxicity risk.