Angist SR 2.6 mg Tablet

Angist SR 2.6 mg Tablet (Sustained Release)

DESCRIPTION

Acting on the vascular smooth muscles, ANGIST (Nitroglycerin) dilates the peripheral veins and arteries as well as coronary vessels, thereby decreases the pre and after load and the oxygen demand of the heart.

COMPOSITION

Each sustained release tablet contains Nitroglycerin USP 2.6 mg.

INDICATIONS

Prophylaxis and treatment of angina; Chronic treatment of coronary artery diseases; left ventricular failure.

DOSAGE & ADMINISTRATION

Recommended initial disage is 1 tablet (2.6 mg) 3 times daily, before breakfast, late afternoon before a meal and before retiring. Dosage may be increased progressively up to 2 tablets 3 times a day.

OR AS DIRECTED BY THE PHYSICIAN

CONTRAINDICATIONS

Hypersensitivity to nitrates; hypotensive conditions; hypertrophic obstructive cardiomyopathy, cardiac tamponade, constrictive pericarditis, marked anaemia.

SIDE-EFFECTS

Postural hypotension, tachycardia; headache, dizziness; less commonly nausea, vomiting, heartburn, flushing, rash.

USE IN PREGNANCY AND LACTATION

There is no evidence relating to the safety of nitrates in pregnancy and lactation and hence should not be administered unless considered essential by the physician.

DRUG INTERACTION

Concomitant administration with other vasodilators, antihypertensive agents, beta-blockers, calcium-channel blockers, diuretics, neuroleptics or tricyclic anti-depressants and the consumption of alcohol may augment the antihypertensive effect of Nitroglycerin. Patients treated previously with organic nitrate compounds(e.g. isosorbide mono-or dinitrate) may require higher Nitroglycerin dosages for the same haemodynamic effects. Concomitant use of Nitroglycerin and Heparin may decrease the effects of Heparin.

SUPPLY

Each box contains 3 X 10 tablets in alu-alu blister strip