Azepam 5mg Tab, 1 strip

Azepam 5mg Tab, 1 strip

DESCRIPTION

Azepam is Diazepam which is a benzodiazepine tranquilizer with anxiolytic, sedative, muscle relaxant and anticonvulsant properties. It is used in the treatment of anxiety and tension states and also as premedication in the control of muscle spasm. lt has Iong duration of action.

COMPOSITION

Each tablet contains Diazepam BP 5 mg.

INDICATIONS

 In the treatment of severe anxiety disorders

 In the short term management of insomnia

 In the control of muscle spasm as in tetanus

 As an anticonvulsant particularly in the management of  status epilepticus and febrile convulsion

 In the management of alcohol withdrawal symptoms

 As a sedative

DOSAGE AND ADMINISTRATION

Adults

 Management of anxiety disorders and relief of symptoms of anxiety : Depending upon the severity of symptoms -2 mg to 10 mg, 2-4 times daily.

 For the short-term management of insomnia associated with anxiety : 5-15 mg at bed time.

 Adjunctively for relief of skeletal muscle spasm: 2 mg to 10 mg, 3 or 4 times daily.

 Adjunctively in convulsive disorders : 2 mg to 10 mg, 2 to 4 times daily.

 Symptomatic relief in acute alcohol withdrawal : 10 mg, 3 or 4 times during the first 24 hours reducing to 5 mg 3 or 4 times daily as needed.

 As premedicant before dental or minor surgical or

other procedures : 5 to 20 mg as single dose or in divided doses. Children Because of varied response to CNS acting drugs, therapy should be initiated with lowest dose and then increases as required. 1 to 2.5 mg, 3 or 4 times daily initially, increases gradually as needed and tolerated.

OR AS DIRECTED BY THE PHYSICIAN.

SIDE EFFECTS

Frequent and mild drowsiness, light headaches, slight ataxia, vertigo, dry mouth, inattention may occur and are dose dependent. Other effects that may be observed rarely include hypotension, gastrointestinal and visual disturbances. In cases of long term medication change in libido may occur.

CONTRAINDICATIONS

Patients with known hypersensitivity to benzodiazepines, acute pulmonary insufficiency; respiratory depression, phobic or obsessional states, chronic psychosis.

PRECAUTIONS

Caution should be observed when giving Azepam to elderly or debilitated patients who are liable to be sensitive to its side effects to patients with renal or hepatic dysfunctions and to patients with closed angle glucoma.

USE IN PREGNANCY AND LACTATION

The use of diazepam during the first trimester of pregnancy should almost always be avoided as it bears a risk of congenital malfomation. Significant amounts of this medicine may pass into breast milk. It should not be used by lactating mothers as it may be harmful to the nursing infant.

USE IN CHILDREN

lt is not recommended for infants under six months of age and especially not for premature infants. lt is used in children for the same indications as in adults.

DRUG INTERACTIONS

Concomitant intake with alcohol is not recommended. Sedation may be increased due to concomitant use of neuroleptics (antipsychotics), hypnotics, sedative antihistamines and CNS depressants e.g., general anesthetics, narcotic analgesics or antidepressants.

Diazepam clearance is increased by concomitant administration of phenobarbitone and is decreased by administration of cimetidine. Omeprazole and isoniazide inhibit diazepam metabolism.

SUPPLY

Each box contains 20x10 tablets in blister strips.