- Stock: In Stock
- Brand: Beximco Pharmaceutical
- Product ID: Azithromycin
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Azithrocin 500mg Tablet — Azithromycin 500mg | Beximco Pharmaceuticals
| Generic Name | Azithromycin Dihydrate 500 mg |
| Dosage Form | Film-coated Tablet |
| Manufacturer | Beximco Pharmaceuticals Ltd. |
| Therapeutic Class | Macrolide Antibiotic (Azalide subclass) |
| Pack Size | 3 tablets per strip (standard 3-day course) |
| Availability | In Stock — Available Online |
Overview
Azithrocin 500mg contains Azithromycin 500 mg — the higher-strength tablet for more severe or systemic infections where the full 500mg daily dose is required from Day 1. The 500mg once-daily dose is standard for community-acquired pneumonia (CAP), typhoid fever, and severe respiratory tract infections, typically given as a 3-day course. It is also the loading dose used in the classic 5-day CAP regimen (500mg on Day 1, then 250mg on Days 2–5). See also: Azithrocin 250mg Tablet for the lower-strength option and the 5-day regimen.
Azithrocin Strength Comparison
| Product | Dose | Typical Regimen | Use Case |
|---|---|---|---|
| Azithrocin 250mg | 250 mg/tablet | 500mg Day 1 (2 tabs), 250mg Days 2–5 | Mild-moderate CAP, skin, pharyngitis, Chlamydia |
| Azithrocin 500mg (this) | 500 mg/tablet | 500mg once daily × 3 days | Moderate-severe CAP, typhoid, sinusitis — convenient once-daily 3-day pack |
| Azithrocin 500 IV | 500 mg/vial | IV infusion × 2–5 days | Severe CAP requiring IV therapy, hospitalised patients |
Indications
- Community-Acquired Pneumonia (CAP) — 3-day 500mg OD regimen for mild-moderate CAP in outpatients
- Acute Bacterial Sinusitis — 3-day course
- Acute Exacerbation of Chronic Bronchitis (AECB)
- Skin & Soft Tissue Infections (uncomplicated)
- Mycobacterium avium Complex (MAC) Prophylaxis — in HIV/AIDS patients (specialist-directed)
Dosage & Administration
| Indication | Dose | Frequency | Duration |
|---|---|---|---|
| CAP (outpatient, mild-moderate) | 500 mg | Once daily | 3 days |
| Acute Bacterial Sinusitis | 500 mg | Once daily | 3 days |
| AECB | 500 mg | Once daily | 3 days |
| Typhoid Fever | 500 mg | Once daily | 7 days |
| Skin & Soft Tissue (loading day) | 500 mg | Day 1 only | Then 250mg × 4 days |
Take with or without food. Swallow whole with water. Do not crush. Complete the prescribed course.
Special Note for Diabetic Patients
Infections — particularly pneumonia and UTIs — frequently destabilise blood glucose control in diabetic patients, causing hyperglycaemia through physiological stress responses. Prompt treatment with Azithrocin 500mg for respiratory infections helps restore glycaemic stability. Note: QT prolongation risk applies — check with your physician if you have heart disease or are on QT-prolonging medications.
Side Effects
- GI (most common): Nausea, diarrhoea, abdominal pain — take with food to reduce
- Cardiac: QT prolongation — risk higher at 500mg dose; avoid in patients with baseline QTc >450ms
- Hepatic: Elevated ALT/AST; rare cholestatic jaundice
- Skin: Photosensitivity, rash; rare SJS/TEN
Drug Interactions
| Drug | Interaction |
|---|---|
| Warfarin | Enhanced anticoagulation — monitor INR |
| QT-prolonging drugs | Additive QT risk — avoid with amiodarone, hydroxychloroquine, haloperidol |
| Antacids (Al/Mg) | Reduce peak concentration — separate by 2 hours |
| Cyclosporine | Increased cyclosporine levels — monitor trough levels |
Storage
- Store below 30°C in a dry place, protected from light. Keep out of reach of children.
FAQ
Q1: Three days seems like a very short course — is it enough?
Yes, for appropriate indications. Azithromycin's unique pharmacokinetics mean therapeutic tissue concentrations persist for 5–7 days after the final dose of a 3-day course. Studies show clinical cure rates with 3-day 500mg OD are non-inferior to longer courses of other antibiotics for CAP, sinusitis, and AECB.
Q2: Can Azithrocin 500mg treat typhoid?
Yes. Azithromycin is now a preferred alternative for uncomplicated typhoid fever, particularly in areas with fluoroquinolone-resistant Salmonella typhi (common in South Asia including Bangladesh). The standard course is 500mg once daily for 7 days. Your physician will determine the appropriate antibiotic based on local resistance patterns.
Q3: What is the difference between Azithrocin 500mg tablet and Azithrocin 500 IV?
Same drug, different routes: the 500mg tablet is for oral use (outpatient or mild-moderate infections). The IV formulation is for intravenous infusion in hospitalised patients with severe pneumonia or those unable to take oral medication. Physicians typically switch patients from IV to oral azithromycin as they improve ("step-down therapy").
Medical Disclaimer: Educational information only. Antibiotics must be used only under physician prescription. Do not self-medicate.
