Ceftiben 400mg Capsule

Overview

Ceftiben 400 mg Capsule contains Ceftibuten Dihydrate, manufactured by Square Pharmaceuticals PLC. It is a third-generation oral cephalosporin antibiotic used for the treatment of mild to moderate bacterial infections including acute bacterial exacerbations of chronic bronchitis, acute otitis media, pharyngitis, tonsillitis, and uncomplicated urinary tract infections.

Dosage and Administration

Adults and adolescents (≥12 years): 400 mg once daily for 7–10 days, or as prescribed. Take on an empty stomach (at least 2 hours after a meal) for optimal absorption.

Interaction

Probenecid may increase ceftibuten plasma levels. Warfarin effect may be enhanced — monitor INR.

Contraindications

Contraindicated in patients with known hypersensitivity to ceftibuten, other cephalosporins, or penicillins.

Side Effects

Diarrhoea, nausea, headache, and abdominal pain. Pseudomembranous colitis is a rare but serious complication.

Pregnancy and Lactation

Use during pregnancy only if clearly necessary (Category B). Small amounts may be excreted in breast milk.

Precautions and Warnings

Dose reduction is required in patients with significant renal impairment. Complete the full prescribed course. Take on an empty stomach for best absorption.

Storage Conditions

Store below 30°C, in a dry place, protected from light and moisture.

Frequently Asked Questions

Why should Ceftiben capsules be taken on an empty stomach?
Food significantly reduces the peak plasma concentration of ceftibuten; taking it at least 2 hours after meals maximises absorption.

Can one Ceftiben 400 mg capsule replace two 200 mg doses?
Yes — the recommended adult dose is a single 400 mg capsule once daily, which achieves the required therapeutic blood levels throughout the day.

This content is for informational purposes only and does not substitute professional medical advice. Please consult a registered physician before taking any medication.