FILFRESH 3mg Tab

Overview

Filfresh (Melatonin 3 mg) is a hormone naturally secreted by the pineal gland that helps regulate other hormones and maintains the body's circadian rhythm. Darkness stimulates melatonin production while light suppresses its activity. Filfresh is indicated for the short-term regulation of sleep patterns including jet lag, insomnia associated with disrupted circadian rhythms, and sleep disorders in children with learning disabilities. Melatonin also possesses antioxidant properties and helps strengthen the immune system.

Dosage and Administration

Adult - Insomnia: 3 to 6 mg one hour before bedtime. Jet lag: 0.5 to 5 mg one hour before bedtime at the final destination, or 1 to 5 mg one hour before bedtime for 2 days prior to departure and 2 to 3 days upon arrival. Depression: 0.125 mg twice in the late afternoon, each dose 4 hours apart. Sarcoidosis: 20 mg per day for 4 to 12 months. Children (6 months to 14 years): 0.30 mg/day for sleep disorders. Always follow the physician's instructions.

Interaction

Antidepressants (desipramine, fluoxetine): melatonin may reduce antidepressant effects; fluoxetine may deplete melatonin levels. Benzodiazepines (triazolam): combination may improve sleep quality. Blood pressure medications: melatonin may reduce effectiveness of methoxamine and clonidine; calcium channel blockers and beta-blockers may decrease melatonin levels. Anticoagulants (warfarin): melatonin may increase bleeding risk. NSAIDs (ibuprofen): may reduce melatonin blood levels. Caffeine, tobacco, and alcohol can diminish melatonin levels.

Contraindications

Contraindicated in patients with autoimmune diseases and in known hypersensitivity to melatonin or any excipient of the formulation.

Side Effects

Possible adverse effects include headache and depression. Drowsiness may occur within 30 minutes of taking Filfresh and may persist for about 1 hour, potentially affecting driving ability and operation of machinery.

Pregnancy and Lactation

Information regarding safety and efficacy in pregnancy and lactation is not available. Use only on the physician's advice.

Precautions and Warnings

Caffeine and fluvoxamine may increase the effects of melatonin. Melatonin may decrease the antihypertensive effect of nifedipine. Do not drive or operate heavy machinery within 1 hour of taking Filfresh. Keep out of reach of children. Do not exceed the recommended dose without medical supervision.

Storage Conditions

Store below 30 degrees C. Keep away from light and moisture. Keep all medicine out of reach of children.

Frequently Asked Questions

Q: How long before bed should I take Filfresh?
A: Take Filfresh approximately one hour before your intended bedtime for best effect in regulating the sleep-wake cycle.

Q: Can Filfresh be used for jet lag?
A: Yes. For jet lag, 0.5 to 5 mg taken one hour before bedtime at the destination helps re-align the body's internal clock. Consult your physician for appropriate timing and dosage.