Flexivan 100 mg Tablet, 1 strip
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- Stock: In Stock
- Brand: NIPRO JMI Pharma Ltd.
- Product ID: Aceclofenac
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Flexivan 100 mg Tablet, 1 strip
Description:
Flexivan (A ceclofenac) is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug. Peak plasma concentration is achieved approximately 1.25 to 3.00 hours following ingestion. Aceclofenac penetrates into the synovial fluid, where the concentration is achieved approximately 57% of those in plasma.
Indication
It is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Dosage & Administration
Adults :Recommended dose is 100 mg, twice daily.
Children : There are no clinical data on the use of Aceclofenac in children.
Children : There are no clinical data on the use of Aceclofenac in children.
Contraindication
Aceclofenac is contraindicated in patients with known hypersensitivity to it or in whom aspirin or NSAIDs precipitate attacks of asthma.
Precaution
Caution should be exercised to patients with active or suspected peptic ulcer or gastro-intestinal bleeding when using Aceclofenac.
Side Effects
Common side effects include- abdominal pain, dyspepsia, nausea, diarrhea. Dermatological complaints including pruritus & rash, abnormal hepatic enzyme levels and raised serum creatinine have occasionally been reported. The majority of side effects observed, have been reversible.
Drug Interaction
Lithium and Digoxin : may increase plasma concentration of lithium and digoxin.
Diuretics : may interact the activity of diuretics.
Anticoagulants : may enhance the activity of anticoagulant.
Methotrexate : may increase the plasma level of methotrexate.
Diuretics : may interact the activity of diuretics.
Anticoagulants : may enhance the activity of anticoagulant.
Methotrexate : may increase the plasma level of methotrexate.
Pregnancy & Lactation
The use of Aceclofenac should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.
Storage Condition
keep in a dry place away from light and heat. Keep out of the reach of children.