- Stock: In Stock
- Brand: Square Pharmaceuticals
- Product ID: Bicarbonate Component [HCO3 Hemodialysis Solution]
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| Generic Name | Bicarbonate Component [HCO₃ Haemodialysis Solution] |
|---|---|
| Strength | Sodium Chloride 30.5 gm + Sodium Bicarbonate 66 gm per litre |
| Dosage Form | Dialysis Solution (Concentrate) |
| Manufacturer | Square Pharmaceuticals PLC |
| Therapeutic Class | Haemodialysis solutions |
| Pack Size | 10 litre container |
Overview
Hemosol-B is the bicarbonate concentrate component of a bicarbonate haemodialysis solution system, manufactured by Square Pharmaceuticals PLC. Each litre of Hemosol-B contains Sodium Chloride 30.5 gm and Sodium Bicarbonate 66 gm. Hemosol-B serves a crucial biochemical role as a physiological pH buffer during haemodialysis, indicated for patients with renal failure, chronic renal failure, and those undergoing haemodialysis. Sodium bicarbonate raises blood and urinary pH by dissociating to provide bicarbonate ions that neutralise excess hydrogen ion concentration. Hemosol-B must always be combined with the acidic component (Hemosol-A) and purified water — it must never be used alone.
Dosage and Administration
Hemosol-B must be combined with the acidic component (Hemosol-A) and purified water in the following dilution ratio per the standard protocol:
Acidic component (Hemosol-A): 1.00 volume | Bicarbonate component (Hemosol-B): 1.83 volumes | Purified water: 34.00 volumes
Administer under the supervision of trained dialysis healthcare professionals according to dialysis machine specifications and clinical protocols.
Interaction
Sodium Bicarbonate may increase the toxicity of amphetamines, ephedrine, pseudoephedrine, flecainide, quinidine, and quinine; and may decrease the effects of lithium, chlorpropamide, and salicylates due to increased clearance. It may also affect the absorption of certain drugs due to raised intragastric pH. Sodium Chloride may affect serum concentrations of lithium. Inform the clinical team of all medications being taken.
Contraindications
Hemosol-B is contraindicated in patients with known hypersensitivity to any of the ingredients of this preparation. Do not use if visible solid particles are present inside the container.
Side Effects
Side effects are those associated with the haemodialysis procedure and are managed by the dialysis team. Potential electrolyte imbalances should be monitored during dialysis sessions.
Pregnancy and Lactation
Use during pregnancy or lactation should be based on strict clinical necessity under the supervision of a physician, as the safety profile in these populations has not been fully characterised in this context.
Precautions and Warnings
Hemosol-B must be used with the acidic component (Hemosol-A) — never alone. Before use, the mixed solution must be further diluted with highly purified water. Close the container tightly immediately after each use. Discard any solution in which visible solid particles are present. Discard solution within 96 hours of first opening. Not for injection. Store below 30°C.
Storage Conditions
Store below 30°C. Not for injection. Keep out of the reach of children. For institutional/hospital use only.
Frequently Asked Questions
Q: What is Hemosol-B used for?
Hemosol-B is the bicarbonate concentrate component used in bicarbonate haemodialysis. It provides the sodium bicarbonate buffer that maintains the correct physiological pH during kidney dialysis procedures in patients with renal failure or chronic renal failure. It must always be combined with Hemosol-A (acidic component) and purified water — never used alone.
Q: How long can Hemosol-B be kept after opening?
Once opened, Hemosol-B must be discarded within 96 hours. The container should be closed tightly immediately after use, and the solution should be discarded if any visible solid particles are observed. It must be stored below 30°C and is for clinical/hospital haemodialysis use only.
