Intracef 15ml paediatric drops

Intracef 100 mg/mL — Composition & Pharmacology

Generic Name: Cefradine (Cephradine)
Manufacturer: Beximco Pharmaceuticals Ltd.
Drug Class: First-generation Cephalosporin Antibiotic
Dosage Form: Oral Drops
Strength: 100 mg/mL

Cefradine is a bactericidal first-generation cephalosporin antibiotic with broad-spectrum activity against gram-positive and selected gram-negative organisms. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), disrupting peptidoglycan cross-linking.

Indications

• Respiratory tract infections: pharyngitis, tonsillitis, lobar pneumonia, bronchitis
• Skin and soft tissue infections
• Urinary tract infections (UTIs) caused by susceptible organisms
• Ear, nose, and throat (ENT) infections including otitis media
• Post-surgical wound infection prophylaxis

Dosage & Administration

Infants and children: 25–50 mg/kg/day in 4 divided doses. Paediatric drops for precise dosing in young children.

Contraindications & Precautions

• Hypersensitivity to cephalosporins or penicillins (10% cross-reactivity)
• Reduce dose in severe renal impairment
• Caution in patients with history of GI disease (colitis)

Side Effects

Common: nausea, diarrhea, abdominal discomfort. Uncommon: hypersensitivity rash, urticaria. Rare: anaphylaxis, pseudomembranous colitis, blood dyscrasias.

Drug Interactions

Probenecid: increases cefradine plasma levels. Loop diuretics (furosemide): increased nephrotoxicity risk. Aminoglycosides: additive nephrotoxicity.

Storage

Store below 30°C, away from moisture and direct sunlight. Keep out of reach of children.

Medical Disclaimer: This information is for reference purposes only and is not a substitute for professional medical advice. Intracef is a prescription/pharmacy medicine. Always consult a qualified physician or pharmacist before use. Self-medication can be harmful. Diabetesstore.com.bd strongly recommends obtaining a valid prescription for this medication.