- Stock: In Stock
- Brand: Square Pharmaceuticals
- Product ID: Misoprostol
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| Generic Name | Misoprostol |
|---|---|
| Strength | 600 mcg |
| Dosage Form | Tablet |
| Manufacturer | Square Pharmaceuticals PLC |
| Therapeutic Class | Drugs acting on the Uterus, Prostaglandin analogues |
| Pack Size | 10 × 1 tablet (10's) |
Overview
Isovent (Misoprostol) 600 mcg Tablet is a synthetic prostaglandin E1 analogue manufactured by Square Pharmaceuticals PLC. The 600 mcg strength is primarily indicated for the prevention and treatment of postpartum hemorrhage. It may also be used for induction of labor and other uterotonic indications as directed by a physician. Misoprostol stimulates uterine contractions and exerts antisecretory and mucosal protective effects in the gastrointestinal tract.
Dosage and Administration
Prevention of postpartum hemorrhage: 600 mcg orally immediately following delivery. Treatment of postpartum hemorrhage: 600 mcg orally or 1000 mcg per rectally. For induction of labor: 25 mcg vaginally every 6 hours (max 200 mcg total) or 100–200 mcg orally every 4 hours up to 6 doses. Always administer under the supervision of a qualified healthcare professional. Dosage for other indications such as gastric ulcer prophylaxis should be determined by the treating physician.
Interaction
There is no evidence of clinically significant interaction between Isovent and cardiac, pulmonary, CNS drugs, or NSAIDs. High doses of antacids may decrease the bioavailability of Misoprostol.
Contraindications
Isovent is contraindicated in patients with a history of allergy to prostaglandins. It is contraindicated in pregnancy when used for ulcer prophylaxis. Induction of labor is contraindicated in acute fetal distress, abruptio placenta, placenta previa, or unexplained vaginal bleeding.
Side Effects
Isovent is generally well tolerated. The most frequent adverse effects involve the GI tract and include diarrhea, abdominal pain, dyspepsia, flatulence, nausea, vomiting, rashes, and dizziness. Diarrhea may be minimized by taking the drug after meals and avoiding magnesium-containing antacids.
Pregnancy and Lactation
Misoprostol is contraindicated in pregnant women when used for NSAID-associated ulcer prophylaxis due to its abortifacient properties. However, it may be used under close medical supervision during labor or for postpartum hemorrhage management. Excretion into breast milk is possible; Isovent is not recommended for nursing mothers unless the benefit outweighs the risk.
Precautions and Warnings
Isovent 600 mcg should only be administered under direct medical supervision, especially when used for uterotonic indications. Fetal heart rate, uterine contractions, and maternal vital signs should be monitored closely during labor induction. Women of childbearing potential using Isovent for ulcer prophylaxis must use effective contraception. Safety and effectiveness in children below 18 years have not been established.
Storage Conditions
Store in a cool and dry place, protected from light and moisture. Keep out of the reach of children.
Frequently Asked Questions
Q: What is Isovent 600 mcg primarily used for?
A: Isovent 600 mcg is primarily used for the prevention and treatment of postpartum hemorrhage (excessive bleeding after childbirth). It may also be used for induction of labor or other uterotonic indications as directed by a physician.
Q: Can Isovent 600 mcg be used at home?
A: No. This high-strength formulation is intended for use in clinical or hospital settings under the direct supervision of a qualified healthcare professional. It should not be self-administered at home.
