- Stock: In Stock
- Brand: Square Pharmaceuticals
- Product ID: Levocarnitine
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| Generic Name | Levocarnitine |
|---|---|
| Strength | 330 mg |
| Dosage Form | Tablet |
| Manufacturer | Square Pharmaceuticals PLC |
| Therapeutic Class | Drugs for muscular energy metabolism |
| Pack Size | 5×6 (30 tablets) |
Overview
Levocar 330 mg Tablet contains Levocarnitine, a naturally occurring substance essential for mammalian energy metabolism, manufactured by Square Pharmaceuticals PLC. Levocarnitine facilitates the transport of long-chain fatty acids across the inner mitochondrial membrane, making them available for beta-oxidation and ATP production. It is the biologically active L-isomer of carnitine and plays a critical role in energy metabolism in skeletal and cardiac muscle, where fatty acids are the primary energy substrate.
Levocar is indicated for chronic fatigue syndrome, heart diseases including congestive heart failure, kidney disease, high cholesterol (hyperlipidemia), intermittent claudication, dementia and memory impairment, Down syndrome, male infertility, and hyperthyroidism.
Dosage and Administration
Adults: 330 mg two or three times daily, depending on clinical response.
Infants and children: 50–100 mg/kg/day in divided doses, with a maximum of 3 g/day. Start at 50 mg/kg/day and adjust based on clinical response. Doses should be spaced evenly throughout the day, preferably during or following meals, and consumed slowly to maximise tolerance.
Interaction
No major clinically significant drug interactions have been reported with Levocarnitine at standard therapeutic doses. Patients with conditions requiring multiple medications should inform their physician before starting Levocar.
Contraindications
There are no absolute contraindications documented for Levocarnitine at therapeutic doses. Use with caution in patients with severely compromised renal function or end-stage renal disease (ESRD) on dialysis, as potentially toxic metabolites (trimethylamine and trimethylamine-N-oxide) may accumulate due to reduced urinary elimination.
Side Effects
Levocar is generally well tolerated. Transient side effects may include nausea, vomiting, abdominal cramps, and diarrhea, particularly if taken too rapidly or at high doses. Gastrointestinal reactions are minimised by consuming doses slowly with food.
Pregnancy and Lactation
There are no adequate and well-controlled studies in pregnant women. Levocar should be used during pregnancy only if clearly needed. Levocarnitine supplementation in nursing mothers has not been specifically studied. Any risks to the infant from excess carnitine intake should be weighed against the benefits to the mother; discontinuation of nursing or of Levocarnitine treatment should be considered if necessary.
Precautions and Warnings
Gastrointestinal reactions may occur with too rapid consumption — take doses slowly and with food to improve tolerance. The safety and efficacy of oral Levocarnitine have not been evaluated in patients with renal insufficiency. In patients with severe renal impairment or ESRD on dialysis, chronic high-dose use may lead to accumulation of TMA and TMAO metabolites. Overdose has not been associated with toxicity, but supportive care is appropriate.
Storage Conditions
Do not store above 30°C. Keep away from light. Keep out of reach of children.
Frequently Asked Questions
Q: What is Levocar 330 mg used for?
A: Levocar 330 mg provides Levocarnitine, a nutrient essential for cellular energy production. It is used in chronic fatigue, heart failure, male infertility, intermittent claudication, and conditions associated with carnitine deficiency or impaired fatty acid metabolism.
Q: When should Levocar tablets be taken?
A: Levocar tablets should ideally be taken during or after meals, with doses spaced evenly throughout the day. This helps improve gastrointestinal tolerance and absorption.
