Metfrom ER 1000

Metfrom ER 1000 — Metformin Hydrochloride (Extended Release, Legacy Listing)

Overview

This is a legacy catalog listing for a 1000 mg extended-release metformin tablet. As pack size and current pricing on this older entry may not reflect the latest pharmacy stock, customers are advised to confirm pack size and price with the pharmacy before ordering.

Mechanism of Action

Metformin reduces hepatic glucose production, decreases intestinal glucose absorption, and improves peripheral insulin sensitivity. The extended-release formulation releases the drug gradually, supporting once-daily dosing.

Indications

Indicated for type 2 diabetes mellitus in patients requiring a higher metformin dose who prefer once-daily extended-release dosing over multiple immediate-release doses.

Dosage and Administration

Usually taken once daily with the evening meal; the maximum recommended dose of metformin extended-release formulations is generally 2000 mg/day. Tablets must be swallowed whole, never crushed or chewed.

Contraindications

Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²), metabolic acidosis including diabetic ketoacidosis, and known hypersensitivity to metformin.

Side Effects

Generally well tolerated when initiated gradually from a lower strength; gastrointestinal symptoms such as nausea or diarrhea can still occur. Long-term use may reduce vitamin B12 absorption.

Drug Interactions

Iodinated contrast media require temporary discontinuation of metformin. Alcohol intake should be limited. Disclose all current medications and supplements to your physician or pharmacist.

Special Precautions

Renal function should be carefully assessed before prescribing this highest extended-release strength and monitored periodically thereafter. Please verify current pricing and pack size with the pharmacy, as this is a legacy catalog entry.

Storage

Store below 30°C in a dry place, protected from light. Keep out of reach of children.

Frequently Asked Questions

Q1: Is this listing's price up to date?
This is a legacy catalog entry; please confirm current pricing and pack size with the pharmacy before ordering.

Q2: Is 1000 mg the maximum extended-release dose available?
It is at or near the upper limit for extended-release formulations; your physician will confirm the appropriate maximum for you.

Q3: Can Metfrom ER 1000 be split into smaller doses?
No, extended-release tablets are designed for once-daily dosing and should not be split unless specifically directed by your physician.

Q4: What should I do if I notice digestive discomfort at this strength?
Contact your physician, who may adjust the dose or timing; do not stop the medication abruptly without medical advice.

Medical Disclaimer: This information is provided for educational purposes only and does not replace professional medical advice. Always consult a registered physician or pharmacist before starting, stopping, or changing any medication. Confirm pack size and current price with the pharmacy before ordering. Dosage and suitability vary by individual health condition.