- Stock: In Stock
- Brand: Beximco Pharmaceutical
- Product ID: Amino Acid, D-Sorbitol & Electrolytes
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Nutrimin-D IV Infusion — Amino Acids + D-Sorbitol + Electrolytes | Beximco Pharmaceuticals
| Generic Name | Amino Acids + D-Sorbitol + Electrolytes IV Infusion |
| Dosage Form | IV Infusion Solution |
| Drug Class | Parenteral Nutrition — Amino Acid Solution with D-Sorbitol |
| Manufacturer | Beximco Pharmaceuticals Ltd. |
| Route | Intravenous Infusion — Hospital Use Only |
| Prescription Status | Hospital / Clinical Use — Prescription Required |
Overview
Nutrimin-D IV Infusion is a parenteral nutrition product providing Amino Acids, D-Sorbitol, and Electrolytes for intravenous use. The "D" designation refers to the D-Sorbitol carbohydrate component, which provides a caloric source partially independent of insulin-mediated glucose transport. This makes Nutrimin-D particularly suited for use in diabetic patients and in situations of impaired glucose tolerance where glucose-based solutions may be problematic. It is used in hospital settings as part of TPN or supplemental parenteral nutrition regimens when enteral feeding is insufficient or contraindicated.
Key Components
| Component | Role |
|---|---|
| Amino Acids (essential + non-essential) | Protein anabolism, nitrogen balance, wound healing, enzyme and immune protein synthesis |
| D-Sorbitol | Caloric energy source; hepatically converted to fructose → glucose; lower immediate glycaemic impact than dextrose |
| Electrolytes | Maintain acid-base balance, osmolality, cellular hydration, nerve and cardiac function |
Clinical Indications
- Parenteral protein supplementation when oral/enteral route unavailable
- Post-operative nutritional support — surgery, trauma, burns
- Severe protein-energy malnutrition requiring IV nutrition
- Catabolic states — sepsis, major illness — where anabolism support is needed
- As part of complete TPN alongside lipid emulsions and micronutrient solutions
Diabetic Patient Considerations
- D-Sorbitol and glycaemia: D-Sorbitol provides energy with lower immediate insulin demand than glucose — however, hepatic conversion to glucose still occurs and blood glucose must be monitored every 1–2 hours during infusion. Sorbitol is NOT recommended in patients with hereditary fructose intolerance.
- Insulin management during TPN: Most diabetic patients on parenteral nutrition require insulin added directly to the TPN bag (typically 0.1–0.2 units per gram of carbohydrate) or via separate IV insulin infusion to maintain euglycaemia.
- Renal function: Amino acid infusions increase the renal nitrogen load — use with caution in diabetic nephropathy. Dose adjustment and specialist guidance required in eGFR <30 mL/min.
- Electrolyte monitoring: Daily potassium, sodium, phosphate, and magnesium levels essential during TPN — insulin-driven K⁺ shifts, refeeding syndrome risk, and diabetes-related electrolyte disturbances all compound each other.
Administration
IV infusion only — via peripheral vein (if osmolality permits) or central venous catheter. Inspect before use; do not administer if cloudy or particulate matter is present. Administer via infusion pump at prescribed rate. Single use — discard unused portion. Strict aseptic technique required.
Side Effects
Hyperglycaemia (monitor BGL), thrombophlebitis (peripheral administration), refeeding syndrome in severely malnourished patients, electrolyte imbalances, catheter-associated infection (central line). Hyperammonaemia with severe hepatic impairment.
Storage
Store at 15–25°C. Do not freeze. Protect from light. Do not use damaged or leaking bags.
Medical Disclaimer: Parenteral nutrition must only be prescribed and administered under clinical supervision with regular biochemical monitoring. Diabetic patients require careful glycaemic management during infusion. Hospital and prescription use only.
