Pedeamin syp 100 ml

Pedeamin 12.5 mg/5 mL — Composition & Pharmacology

Generic Name: Diphenhydramine Hydrochloride
Manufacturer: Beximco Pharmaceuticals Ltd.
Drug Class: First-generation Antihistamine (H1 antagonist)
Dosage Form: Syrup
Strength: 12.5 mg/5 mL

Diphenhydramine is a first-generation H1 antihistamine with anticholinergic, antiemetic, and sedative properties. It competitively blocks histamine H1 receptors, reducing symptoms of allergic reactions. Its CNS penetration provides sedative and anti-motion sickness effects.

Indications

• Allergic rhinitis and seasonal allergies
• Urticaria, pruritus, and insect bite reactions
• Motion sickness prevention and treatment
• Mild insomnia (short-term management)
• Nausea and vomiting including morning sickness

Dosage & Administration

Children 2–5 years: 5 mL (12.5 mg) every 4–6 hours. Children 6–12 years: 5–10 mL (12.5–25 mg) every 4–6 hours. Adults: 10–20 mL (25–50 mg) every 4–6 hours. Maximum 4 doses in 24 hours.

Contraindications & Precautions

• Hypersensitivity to diphenhydramine
• Neonates and premature infants
• Acute asthma, lower respiratory disease
• Concurrent MAO inhibitor use
• Narrow-angle glaucoma, urinary retention, prostatic hypertrophy

Side Effects

Very common: sedation, somnolence. Common: dry mouth, blurred vision, urinary retention, constipation. Children may experience paradoxical CNS stimulation (excitability, insomnia).

Drug Interactions

CNS depressants (alcohol, sedatives, anxiolytics): additive sedation. MAO inhibitors: enhance anticholinergic effects. Tricyclic antidepressants: additive CNS/anticholinergic effects.

Storage

Store below 30°C, away from moisture and direct sunlight. Keep out of reach of children.

Medical Disclaimer: This information is for reference purposes only and is not a substitute for professional medical advice. Pedeamin is a prescription/pharmacy medicine. Always consult a qualified physician or pharmacist before use. Self-medication can be harmful. Diabetesstore.com.bd strongly recommends obtaining a valid prescription for this medication.