TPC (100 mg+100 mg+1 mg) IM Injection

TPC (100 mg+100 mg+1 mg) IM Injection

COMPOSITION

TPC TABLET : Each film-coated tablet contains : Thiamine Mononitrate (Vit. B1) BP 100 mg Pyridoxine Hydrochloride (Vit. B6) BP200 mg Cyanocobalamin (Vit. B12) BP 200 mcg.

TPC INJECTION : Each 3 ml ampoule contains: Thiamine Hydrochloride (Vit. B1) BP 100 mg Pyridoxine Hydrochloride (Vit. B6) BP 100 mg Cyanocobalamin (Vit. B12) BP 1mg.

DESCRIPTION

TPC is a combination of vitamin B1 (thiamine), B6 (pyridoxine hydrochloride) and B12 (cyanocobalamin). The vitamins B1, B6 and

B12 are indispensable for a normal course of the nervous metabolism. TPC supports the regeneration of nerve fibers and myelin sheath by activation of the metabolism and the natural repair mechanism. The combination of these three vitamins shows better efficacy than that of the individual vitamin.

INDICATIONS

TPC is indicated where a deficiency of the relevant vitamins exists. It is indicated in the treatment of polyneuropathy of any origin such as diabetic, alcoholic or toxic neuropathies, neuritis, cervical syndrome, shoulder-arm syndrome, sciatica, peripheral neuralgia, facial neuralgia, lumbago, intercostal neuralgia, myalgia, spinal pain and Herpes Zoster.

DOSAGE AND ADMINISTRATION

Tablets : 1 to 3 tablets daily or as directed by the physician.

Injection : Ampoules are preferably injected intramuscularly (deep intragluteal). In severe cases, 1 ampoule daily until the acute symptoms subside. For milder cases and follow up therapy, 2 to 3 ampoules per week.

SIDE EFFECTS

Generally well tolerated. In rare cases, few allergic reactions may be seen.

USE IN PREGNANCY & LACTATION

Sufficient data is not available in this respect.

PRECAUTIONS

Cyanocobalamin should not be given before a diagnosis has been fully established because of the possibility of masking symptoms of subacute degeneration of the spinal cord. Cyanocobalamin is not a suitable form of vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.

CONTRAINDICATIONS

Should not be used in patients on Levodopa therapy.

Hypersensitivity to any ingredient of the product.

DRUG INTERACTIONS

No significant drug interactions have been reported.

SUPPLY

TPC Tablet: Each box contains 4 x 8 tablets in blister strips.

TPC Injection: Each box contains 2 x 3 ampoules.