Tulos 100 ml Syrup

Tulos 3.35 gm/5 ml Syrup,100 ml

DESCRIPTION

TULOS (Lactulose) is a disaccharide which is poorly absorbed from the gastrointestinal tract and as no enzyme capable of hydrolysis of this disaccharide present in human gastrointestinal tissue, oral dosage of TULOS reach the colon virtually unchanged.

By the action of colonic bacteria, Lactulose is broken down primarily to lactic acid and also to small amounts of formic and acetic acids, which results in an increase in osmotic pressure and slight acidification of the colonic contents. This in turn causes an increase in stool water content and softening of stool.

On the other hand, low faecal PH discourages the proliferation of ammonia- producing organisms in the colon and TULOS (Lactulose) therefore is useful in the treatment of hepatic encephalopathy.

COMPOSITION

Each 5 ml TULOS concentrated oral solution contains Lactulose

BP 3.35 g.

INDICATIONS

Constipation

Hepatic encephalopathy (portal systemic encephalopathy)

DOSAGE AND ADMINISTRATION

Adult (including elderly)

Constipation: Initially 15 ml twice daily, adjusted according to patient's need.

Child

5-10 years:10 ml twice daily.

1-5 years: 5 ml twice daily.

under 1 year: 2.5 ml twice daily.

Tulos may, if necessary, be taken with water or fruit juice.

Hepatic Encephalopathy:

30-50 ml 3 times daily, subsequently adjusted to produce 2-3 soft stools daily.

OR AS DIRECTED BY THE PHYSICIAN.

CONTRAINDICATION

In common with other preparations used for the treatment of constipation, Lactulose should not be used in patients with ngastrointestinal obstructions. Lactulose should not be given to patients with galactosaemia.

PRECAUTIONS

Care should be taken in patients with lactose intolerance.

USE IN PREGNANCY AND LACTATION

FDA approved pregnancy category B. Lactulose should be usednwith caution during the first trimester of pregnancy.

Nursing mothermIt is not known whether Lactulose is excreted in human milk.

Therefore, caution should be exercised when Lactulose is administered to a nursing woman.

SIDE EFFECTS

Flatulence, cramps and abdominal discomfort may occur.

DRUG INTERACTIONS

There are no known interactions involving Lactulose.

SUPPLY

Tulos 100 ml : Each bottle contains 100 ml Tulos (Lactulose) concentrated oral solution.

Tulos 200 ml : Each bottle contains 200 ml Tulos (Lactulose) concentrated oral solution with a measuring cup.