- Stock: In Stock
- Brand: Beximco Pharmaceutical
- Product ID: Amoxicillin Trihydrate
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Tycil DS 250mg/5ml Suspension 100ml — Amoxicillin Double-Strength | Beximco Pharmaceuticals
| Generic Name | Amoxicillin Trihydrate — 250 mg per 5 mL (DS = Double Strength) |
| Dosage Form | Powder for Oral Suspension — 100 mL bottle |
| Manufacturer | Beximco Pharmaceuticals Ltd. |
| Therapeutic Class | Aminopenicillin — Broad-Spectrum Beta-Lactam Antibiotic |
| DS = Double Strength | Twice the amoxicillin concentration of standard Tycil suspension (250mg vs 125mg per 5mL) |
| Availability | In Stock — Available Online |
Overview
Tycil DS is the double-strength amoxicillin suspension, containing 250 mg of Amoxicillin Trihydrate per 5 mL — twice the concentration of the standard Tycil 125mg/5ml suspension. The DS (double-strength) formulation provides two key advantages: (1) smaller volume per dose — for a given weight-based dose, the child drinks half the volume compared to standard suspension; (2) enables higher total daily doses (up to 80–90 mg/kg/day) for severe or resistant infections while keeping volumes practical. It is commonly used for moderate-to-severe otitis media, high-dose amoxicillin regimens for resistant S. pneumoniae, and in larger children who need higher doses.
Standard vs DS Suspension Comparison
| Feature | Tycil 125mg/5mL | Tycil DS 250mg/5mL |
|---|---|---|
| Amoxicillin per 5mL | 125 mg | 250 mg (2×) |
| Volume for 250mg dose | 10 mL | 5 mL (half volume) |
| Suitable for high-dose regimens? | Yes, but requires larger volumes | Yes — more practical |
| Typical patients | Standard dose, smaller children | Moderate-severe infections, larger children, high-dose regimens |
Indications
- Moderate-to-Severe Acute Otitis Media — high-dose amoxicillin (80–90 mg/kg/day) for suspected resistant S. pneumoniae
- Acute Bacterial Sinusitis (severe or prolonged)
- Community-Acquired Pneumonia (higher-dose regimen)
- Children requiring 50mg/kg/day or higher — DS formulation reduces dose volume
- Same bacterial spectrum as standard Tycil suspension
Dosage
| Dose Regimen | Child Weight | Volume per Dose (DS 250mg/5mL) | Frequency |
|---|---|---|---|
| Standard (25mg/kg/day ÷ 3) | 10 kg | ~1.7 mL | 3× daily |
| High-dose (80mg/kg/day ÷ 3) | 10 kg | ~5.3 mL | 3× daily |
| High-dose (80mg/kg/day ÷ 3) | 15 kg | ~8 mL | 3× daily |
| High-dose (80mg/kg/day ÷ 3) | 20 kg | ~10.7 mL | 3× daily |
Always follow physician's exact prescription. Reconstitute with cool boiled water as directed on the bottle label. Shake well before each dose. Use the oral dosing syringe provided.
After Reconstitution — Stability
- Stable 7 days at room temperature (below 25°C) or 14 days refrigerated (2–8°C)
- Do NOT freeze. Shake well before each use. Discard after course completion or stability period.
Side Effects
- GI: Diarrhoea, nausea — give with food/milk to reduce
- Skin: Non-allergic rash (especially with viral infections); urticaria (true allergy)
- Oral candidiasis with prolonged courses
- Anaphylaxis (very rare)
Storage (Before Reconstitution)
- Store dry powder below 25°C, protected from light and moisture. Keep out of reach of children.
FAQ
Q1: Why did my doctor prescribe the DS suspension instead of the regular one?
Your physician may have prescribed the DS (250mg/5mL) because your child needs a higher dose per kg bodyweight for their infection severity, or because the higher concentration means your child has to drink less liquid per dose — which can be important for children who resist taking medicine or for very high-dose regimens where the volume of standard suspension would be impractical.
Q2: Can I use the DS suspension for an adult?
Adults generally take Tycil capsules (250mg or 500mg). The DS suspension can technically be used in adults but is generally not practical due to the large volumes needed (e.g., a 500mg adult dose would require 10mL). Capsules are the preferred form for adults who can swallow.
Medical Disclaimer: Educational information only. Paediatric antibiotic doses must be prescribed by a licensed physician and calculated based on the child's current weight.
