- Stock: In Stock
- Brand: Incepta Pharmaceuticals
- Product ID: Verapamil Hydrochloride
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| Generic Name | Verapamil Hydrochloride |
| Brand Name | Veracal |
| Manufacturer | Incepta Pharmaceuticals Ltd., Bangladesh |
| Dosage Form | Tablet |
| Strength | 40 mg |
| Pack Size | Blister Strip |
| Drug Class | Calcium channel blocker (L-type, non-dihydropyridine) |
| Prescription Required | Yes — Rx Only |
| Onset / Peak / Duration | Immediate-release; dosed 3-4 times daily |
What is Veracal?
Veracal (Verapamil Hydrochloride) is an L-type calcium channel blocker manufactured by Incepta Pharmaceuticals Ltd., used for essential hypertension, angina, and supraventricular arrhythmias.
Indications
Essential hypertension, angina pectoris and prevention of re-infarction, supraventricular arrhythmias.
Pharmacology
Verapamil is an L-type calcium channel blocker with antiarrhythmic, antianginal, and antihypertensive activity. It is a negative inotropic agent and should not be used in severe left ventricular dysfunction or hypertrophic cardiomyopathy.
Dosage & Administration
Dose individualized by titration; administer with food. Essential hypertension: 180 mg each morning initially, titrated upward as needed. Angina: 80-120 mg three times daily. Arrhythmias in digitalized patients: 240-360 mg/day in divided doses.
Interaction
Increased plasma levels with CYP3A4 inhibitors (erythromycin, ritonavir), cimetidine; decreased with CYP3A4 inducers (rifampicin), phenobarbital. Increases plasma levels of digoxin, beta-blockers, statins, carbamazepine, and others. Potentiates hypotensive effect of diuretics/antihypertensives.
Contraindications
Severe left ventricular dysfunction, hypotension/cardiogenic shock, sick sinus syndrome, second/third-degree AV block, atrial flutter/fibrillation with accessory pathway (WPW), hypersensitivity to verapamil.
Side Effects
Constipation, nausea, hypotension, edema, bradycardia, AV block, dizziness, headache, fatigue, rash, elevated liver enzymes.
Pregnancy & Lactation
Use only if clearly needed; crosses placenta. Excreted in breast milk — discontinue nursing during use.
Precautions & Warnings
Caution in first-degree AV block, bradycardia, hypotension, atrial fibrillation/flutter with pre-excitation, heart failure. May impair ability to drive; prolongs alcohol effects.
Therapeutic Class
Calcium-channel blockers
Storage Conditions
Do not store above 30°C. Keep away from light and out of reach of children.
