Azolin 0.025% Nasal Drop

Azolin 0.025% Nasal Drop

DESCRIPTION

Oxymetazoline Hydrochloride is an imidazoline derivative sympathomimetic amine. It is a direct agonist at -adrenoceptors but has no actions on -adrenoceptors. It is used as a topical agent on the nasal mucosa, produces a rapid and long acting vasoconstriction of the arterioles, thus reducing blood flow and diminishing swelling of the mucosa. This results in improved potency of the airway and drainage of nasal sinuses.

COMPOSITION

Azolin 0.05% Nasal Drops: Each ml contains Oxymetazoline Hydrochloride USP 0.5 mg. Azolin 0.025% Paediatric Nasal Drops: Each ml contains Oxymetazoline Hydrochloride USP 0.25 mg.

INDICATIONS AND USES

It is indicated for relief of nasal congestion associated with acute & chronic rhinitis, common cold, sinusitis and hay fever or other allergies. It is also used decongestant in otitis media.

DOSAGE AND ADMINISTRATION

Adult & Children 6 years of age: 2 to 3 drops of Azolin 0.05% Nasal Drops in each nostril twice daily in the morning and evening. Children 2-5 years of age: 2 to 3 drops of Azolin 0.025% Nasal Paediatric Drops in each nostril twice daily in the morning & evening. Dosage for children younger than 2 years of age has not been established. Oxymetazoline Hydrochloride should be used for no longer than 3-5 days.

OR AS DIRECTED BY THE PHYSICIAN.

SIDE EFFECTS

When this medicine is used for short period of time at low doses, side effects usually are rare. However stinging, burning, sneezing, increased nasal discharge, drying of the nostrils, and altered taste may occur.

CONTRAINDICATIONS

Contraindicated in patients hypersensitivity to Oxymetazoline or any other components of the product, MAO inhibitors and Tricyclic antidepressants.

PRECATIONS

Recommended dose should not be exceeded or it should not be used for long time. Patients sensitive to other nasal decongestants may be sensitive to this medication also.

USE IN PREGNANCY & LACTATION

Safe use of Oxymetazoline during pregnancy has not been established. Pregnant women should avoid it. It is not known whether Oxymetazoline is secreted in human breast milk. So, caution should be exercised when administering to a nursing mother.

USE IN CHILDREN

Children under 5 years of age should not use Azolin 0.05% Nasal Drops. Children with ages between 2 to 5 years can suitably use Azolin 0.025% Paediatric Nasal Drops. This drug is not recommended under the age of 2 years.

DRUG INTERACTIONS

Oxymetazoline causes Hypertensive crisis if used simultaneously with MAO inhibitors or Tricyclic antidepressants.

OVERDOSAGE

Following a proper application, system action is unlikely. If, however, some of the drops are swallowed, systemic effect can be produced. Symptoms include rapid, irregular heartbeat, headache, dizziness, increase sweating, and nervousness. Such symptoms are more likely to be seen in children.

SUPPLY

Azolin 0.05% Nasal Drops: Each plastic dropper bottle contains 10 ml 0.05% nasal drops.

Azolin 0.025% Paediatric Nasal Drops: Each plastic dropper bottle contains 10 ml 0.025% paediatric nasal drops.