- Stock: In Stock
- Brand: Renata
- Product ID: Cefotaxime
100% Secure Payment
bKash | Nagad | Cards via SSLCommerz | COD
Monthly Medicines Available | Free Delivery on Eligible Orders
This Item is for pre order
Cefotax 250mg Injection — Cefotaxime 250mg | Beximco Pharmaceuticals
| Generic Name | Cefotaxime Sodium 250 mg |
| Dosage Form | Powder for Injection (IM/IV) |
| Drug Class | Third-Generation Cephalosporin (Beta-lactam Antibiotic) |
| Manufacturer | Beximco Pharmaceuticals Ltd. |
| Prescription Status | Prescription Only — Hospital / Clinical Use |
| Route | Intramuscular (IM) or Intravenous (IV) |
Overview
Cefotax 250mg contains Cefotaxime Sodium 250mg — a third-generation cephalosporin antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria. Cefotaxime achieves excellent tissue concentrations including the cerebrospinal fluid (CSF), making it a first-line agent for bacterial meningitis. It is widely used in hospitals for pneumonia, septicaemia, complicated urinary tract infections, intra-abdominal infections, and severe diabetic infections requiring parenteral therapy. The 250mg strength is used for moderate infections in adults and weight-based dosing in children and neonates.
Indications
- Community-acquired and hospital-acquired pneumonia
- Bacterial meningitis (Gram-negative and streptococcal)
- Septicaemia and bacteraemia
- Complicated UTI and pyelonephritis
- Intra-abdominal infections (peritonitis, cholangitis — combined with metronidazole)
- Diabetic foot and soft tissue infections with systemic or Gram-negative involvement
- Neonatal sepsis and paediatric infections
- Gonorrhoea (single dose)
Dosage and Administration
| Indication | Adult Dose | Frequency |
|---|---|---|
| Moderate infections | 1 g IV/IM | Every 8–12 hours |
| Severe infections / meningitis | 2 g IV | Every 4–6 hours |
| Paediatric (<50 kg) | 50–200 mg/kg/day | Divided every 6–8 hours |
| Neonates | 50 mg/kg/day | Every 12 hours |
Reconstitute with sterile water for injection. IV: slow injection over 3–5 minutes or infusion over 20–60 minutes. IM: lidocaine as diluent reduces injection pain. Dose adjustment required in renal impairment. Always obtain cultures before starting antibiotics.
Diabetic Patient Notes
- Severe diabetic infections rapidly progress to systemic sepsis — prompt IV antibiotic therapy is critical
- Infection-driven hyperglycaemia requires intensive glucose monitoring and IV insulin during hospitalisation
- Check eGFR — diabetic nephropathy may require dose reduction
- For polymicrobial diabetic foot infections, combine with metronidazole for anaerobic coverage; consider anti-MRSA cover if risk factors present
Side Effects and Contraindications
Injection site pain/phlebitis, GI upset, skin rash (uncommon), anaphylaxis (rare — ~1–2% cross-reactivity with penicillin), C. difficile colitis (uncommon). Contraindicated in cephalosporin hypersensitivity; caution with severe penicillin allergy.
Storage
Store below 25°C, protected from light. Use reconstituted solution within 6 hours at room temperature or 24 hours refrigerated. Keep out of reach of children.
Medical Disclaimer: For educational purposes only. Injectable antibiotic — hospital/clinical use only. Prescription required. Diabetic patients with signs of severe infection require emergency medical evaluation.
