Napa One 1000 mg Tablet, 1 strip

Napa 1000 mg — Composition & Pharmacology

Generic Name: Paracetamol (Acetaminophen)
Manufacturer: Beximco Pharmaceuticals Ltd.
Drug Class: Analgesic / Antipyretic
Dosage Form: Tablet
Strength: 1000 mg

Paracetamol is a centrally acting analgesic and antipyretic. It inhibits prostaglandin synthesis in the CNS and reduces fever by acting on the hypothalamic heat-regulating center. Unlike NSAIDs, it does not irritate the gastric mucosa. The 1000 mg strength provides stronger analgesic coverage for moderate pain and is suitable for adults who require higher-dose paracetamol therapy.

Indications

• Relief of mild to moderate pain: headache, toothache, backache, rheumatic and muscle pain
• Reduction of fever in common cold, influenza, and other febrile conditions
• Post-operative pain management as part of multimodal analgesia
• Suitable for patients who cannot tolerate aspirin or NSAIDs

Dosage & Administration

Adults and children over 12 years: 500 mg–1000 mg every 4–6 hours as needed. Maximum 4000 mg per 24 hours. Elderly: reduce frequency in renal/hepatic impairment.

Contraindications & Precautions

• Hypersensitivity to paracetamol or any excipient
• Severe hepatic impairment or active liver disease
• Caution in chronic alcohol use (>3 alcoholic drinks/day)
• Avoid concurrent use with other paracetamol-containing products
• Overdose may cause fatal hepatic necrosis — do not exceed recommended dose

Side Effects

Well tolerated at recommended doses. Rare: skin rash, urticaria, angioedema, blood dyscrasias (thrombocytopenia, leukopenia). Hepatotoxicity occurs with overdose.

Drug Interactions

Warfarin: enhances anticoagulant effect with regular use — monitor INR. Isoniazid, rifampicin, carbamazepine, alcohol: increase hepatotoxic risk. Probenecid: raises paracetamol levels. Cholestyramine: reduces absorption.

Storage

Store below 30°C, away from moisture and direct sunlight. Keep out of reach of children.

Medical Disclaimer: This information is for reference purposes only and is not a substitute for professional medical advice. Napa is a prescription/pharmacy medicine. Always consult a qualified physician or pharmacist before use. Self-medication can be harmful. Diabetesstore.com.bd strongly recommends obtaining a valid prescription for this medication.