Raditil 20 mg

Raditil is a pain relieving medicine. It is used for the treatment of moderate to severe pain in conditions like osteoporosis and rheumatoid arthritis. Raditil should be taken with food. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.

Uses of Raditil

• Pain relief
• Rheumatoid arthritis

Side effects of Raditil

• Vomiting
• Nausea
• Stomach pain
• Indigestion
• Diarrhea

How to use Raditil

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Raditil is to be taken with food.

How Raditil works

Raditil is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).

What if you forget to take Raditil?

If you miss a dose of Raditil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Indication

Pain and inflammation associated w/ musculoskeletal and joint disorders

Administration

Should be taken with food. Take w/ or immediately after meals.

Adult Dose

Oral Acute musculoskeletal disorders; Osteoarthritis; Rheumatoid arthritis Adult: 20 mg as a single dose, taken at the same time each day. Max: 40 mg/day (short term use). Treatment duration: Up to 7 days for acute musculoskeletal disorders and up to 14 days for severe cases. Elderly: Use the lowest effective dose for the shortest possible duration.

Contraindication

Active or history of recurrent GI bleed or peptic ulcer, hypersensitivity to NSAIDs, severe heart failure, haemorrhagic diathesis, asthma, pregnancy (3rd trimester).

Mode of Action

Tenoxicam is a potent inhibitor of prostaglandin synthesis by blocking the enzyme cyclo-oxygenase. Additional actions contributing to its anti-inflammatory effect includes inhibition of leucocyte function including phagocytosis and chemotaxis, and scavenging free O2 radicals. It has no effect on renal function at the usual doses.

Precaution

Patient w/ history of or active bronchial asthma, uncontrolled HTN, CHF, established ischaemic heart disease, peripheral arterial disease, cerebrovascular disease, risk factors for CV disease (e.g. HTN, hyperlipidaemia, DM, smoking), history of GI disease, fluid retention and oedema. Patient who will undergo major surgery (e.g. joint replacement). Elderly. Renal and hepatic impairment. Monitoring Parameters Monitor renal, hepatic and cardiac functions.

Side Effect

Dyspepsia, nausea, abdominal pain and discomfort, constipation, diarrhoea, flatulence, indigestion, epigastric distress, stomatitits, anorexia; peripheral oedema; headache, dizziness; allergic reactions, asthma, bronchospasm, dyspnoea, rash, pruritus; decreased Hb, anaemia, thrombocytopenia, non-thrombocytopenic purpura, leucopenia, eosinophilia, epistaxis; increased serum transaminase levels; swollen eyes, blurred vision, eye irritation, malaise, tinnitus; oedema, HTN, cardiac failure. Potentially Fatal: Peptic ulceration, GI bleeding, anaphylaxis, Lyell's syndrome, Stevens-Johnson syndrome, exfoliative dermatitis, nephrotoxicity, arterial thrombotic events (e.g. MI or stroke), hepatitis, jaundice.

Interaction

Increased risk of adverse effects (particularly GI) w/ salicylates and other NSAIDs. May enhance the anticoagulant effect of warfarin and other anticoagulants. May reduce the effect of antihypertensive drugs. Increased risk of nephrotoxicity w/ ciclosporin. Increased risk of convulsions w/ quinolones. May decrease the elimination of lithium. May interfere w/ the natriuretic action of diuretics. May enhance the toxicity of methotrexate. May reduce the effects of mifepristone. Increased risk of GI bleeding w/ corticosteroids.