A-Clox 500 mg/vial Injection

A-Clox 500 mg/vial Injection

DESCRIPTION

A-CLOX is a bactericidal antibiotic that is particularly useful against penicillinase producing Staphylococci. It is a semisynthetic member of the penicillin family. It kills bacteria by interfering the synthesis of the bacterial cell wall. A-CLOX is widely used against Gram-positive bacteria.

COMPOSITION

A-CLOX capsule : Each capsule contains Cloxacillin Sodium BP equivalent to Cloxacillin 500 mg.

A-CLOX Powder for Syrup : Each 5 ml contains Cloxacillin Sodium BP equivalent to 125 mg Cloxacillin after reconstitution.

A-CLOX 250 mg Injection : Each vial contains sterile Cloxacillin Sodium BP equivalent to 250 mg Cloxacillin.

A-CLOX 500 mg Injection : Each vial contains sterile Cloxacillin Sodium BP equivalent to 500 mg Cloxacillin.

INDICATIONS

 Respiratory tract infection : Bronchitis Bronchiectasis, otitis media, sinusitis, pneumonia, tonsillitis, pharyngitis.

 Skin and soft tissue infections : Cellulitis, styes, furuncles, pemphigus, breast abscess, carbuncles, infected burns.

 Other infections : Osteomyelitis, acute and subacute endocarditis, urinary tract infections, obstetric infections, prophylaxis in neonatal infections.

DOSAGE AND ADMINISTRATION

Adults : Oral : 500 mg six hourly ½ -1 hour before meals Intramuscular injection : 250 mg every 4-6 hours. Intravenous injection : 500 mg every 4-6 hours. In serious infections dosage may be doubled. Children (2-10 years) : 1-2 tea spoonful 6 hourly or ½ of the adult dose. Upto 2 years : ¼ of the adult dose.

OR AS DIRECTED BY THE PHYSICIAN

Injection Administration

For Intramuscular injection : 250 mg and 500 mg are to be dissolved with 1.5 ml and 2 ml water for injection BP respectively before administration. For Intravenous injection : 500 mg is to be dissolved with 5-8 ml water for injection BP administered by slow injection for 3 to 4 minutes. Adequately diluted A-CLOX injection can be administered into the drip tube slowly over a period of 3 to 4 minutes.

CONTRAINDICATIONS

Cloxacillin is contraindicated to Penicillin hypersensitive patients.

SIDE EFFECT

Occasional rashes, nausea, diarrhoea or indigestion may rarely be reported.

SUPPLY

Capsule : Box containing 1010 capsules in strips

Powder for Syrup : Bottle containing required amount of powder to

prepare 100 ml syrup.

A-CLOX 250 mg injection : Box contains 5 blister packs each containing

one vial and one 5 ml ampoule of water for injection.

A-CLOX 500 mg injection : Box contains 5 blister packs each containing

one vial and one 5 ml ampoule of water for injection.