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Maxpime 500 IM/IV injection

Maxpime 500 IM/IV injection, Cefepime Hydrochloride, Cefepime
Maxpime 500 IM/IV injection
Tk301
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Indication:
The recommended adult and pediatric dosages and routes of administration are outlined in the
following table. MaxpimeTM (Cefepime) should be administered intravenously over
approximately 30 minutes. Before administration ensure that the powder has been fully dissolved in the solution.

Dosage & Administration:

Site and Type of InfectionDoseFrequencyDuration (Days)
Moderate to Severe Pneumonia1–2 g IVEvery 12 hours10
Empiric therapy for febrile neutropenic patients2 g IVEvery 8 hours7*
Mild to Moderate Uncomplicated or Complicated Urinary Tract Infections0.5-1 g IV/IM**Every 12 hours7-10
Severe Uncomplicated or Complicated Urinary Tract Infections2 g IVEvery 12 hours10
Moderate to Severe Uncomplicated Skin and Skin Structure Infections2 g IVEvery 12 hours10
Complicated Intra-abdominal Infections2 g IVEvery 12 hours7-10



*or until resolution of neutropenia. In patients whose fever resolves but who remain neutropenic for more than 7 days, the need for continued antimicrobial therapy should be re-evaluated frequently.
**Intramuscular route of administration is indicated only for mild to moderate, uncomplicated or complicated UTIs due to E. coli when the intramuscular route is considered to be a more appropriate route of drug administration.

Pediatric Patients (2 months up to 16 years)
The maximum dose for pediatric patients should not exceed the recommended adult dose. The usual recommended dosage in pediatric patients up to 40 kg in weight for uncomplicated and complicated urinary tract infections (including pyelonephritis), uncomplicated skin and skin structure infections, and pneumonia is 50 mg per kg per dose, administered every 12 hours (50 mg per kg per dose, every 8 hours for febrile neutropenic patients), for durations as given above.

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