Citrosol 200 ml Solution

Citrosol (1500 mg+250 mg)/5 ml Solution,200 ml bottle

Composition

Each 5 ml oral clear solution contains Potassium Citrate BP 1500 mg and Citric Acid Monohydrate BP 250 mg.

Indications

For the symptomatic relief of dysuria associated with mild urinary tract infections, especially cystitis.

Dosage and Administration

Adults including the elderly and children over 6 years:

CITROSOL 10 ml solution three times daily. CITROSOL Oral solution should be taken diluted with one glassful of water (250 ml) followed by additional water, if desired. Children 1-6 years of age: 5 ml CITROSOL oral solution three times daily. CITROSOL oral solution should be taken diluted with half glassful of water (125 ml) followed by additional water, if desired.

OR AS DIRECTED BY THE PHYSICIAN.

Side effects

CITROSOL oral solution generally well tolerated without any unpleasant side effects when given in recommended doses to patients with normal renal function and urinary output. In some cases Mild nausea and occasionally vomiting may occur due to gastric irritation.

Contraindications

CITROSOL oral solution is contraindicated in hyperkalemia, renal dysfunction, ventricular arrhythmics, Addison’s disease and in known hypersensitivity to Potassium Citrate or any other ingredient of the product.

Precautions

CITROSOL oral solution provides symptomatic relief only and is not an anti-bacterial. Effective anti-bacterial therapy should be co-prescribed. It should be used with caution when renal or cardiac dysfunction is present. Citrate mobilizes calcium from bones and increases its urinary excretion. This together with raised urinary pH may predispose to formation of stones in the urinary tract.

Use in pregnancy and lactation

There are no adequate data from the use of CITROSOL oral solution in pregnant women. Animal studies are insufficient with respect to effects on pregnancy. The potential risk to humans is unknown. CITROSOL oral solution should not be used during pregnancy unless clearly necessary and on the advice of a physician.

Drug Interactions

Concurrent administration of Potassium containing or sparing medications may lead to hyperkalaemia. May interact with cardiac glycosides. Citrates alkalinize the urine and thus may alter the urinary excretion of a number of drugs. Particularly noteworthy is the diminished anti-bacterial activity of nitrofurantoin.

Overdose

Over dosage is accompanied by nausea, vomiting, abdominal pain and symptoms due to hyperkalaemia and metabolic acidosis. Fluid and electrolyte balance together with ECG should be closely monitored. Treatment is symptomatic and supportive. Moderate to severe hyperkalemia is a medical emergency requiring prompt correction.

Supply

Each PET bottle contains 200 ml Solution.