- Stock: Out Of Stock
- Brand: Acme Laboratories Limited
- Product ID: Diclofenac Sodium
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A-Fenac SR 100 mg Tablet — 1 Strip Pack (Diclofenac Sodium SR) — Product Overview
| Quick Reference | |
|---|---|
| Brand Name | A-Fenac SR Tablet 100 mg (1 Strip) |
| Generic Name | Diclofenac Sodium 100 mg Sustained-Release |
| Drug Class | NSAID — Sustained-Release Oral Tablet |
| Manufacturer | ACI Limited, Bangladesh |
| Pack Size | 1 strip (single strip — for trial or short-term acute use) |
| Duration of Action | 12–16 hours per tablet — once or twice daily dosing |
| Key Note | Do not crush or chew — swallow whole to preserve SR matrix |
| Prescription Status | Prescription Required |
What is A-Fenac SR 100 mg (1 Strip)?
This is the 1-strip pack of A-Fenac SR 100 mg — the sustained-release diclofenac sodium tablet — providing a small quantity for short-term acute pain episodes, for patients starting NSAID therapy who want to assess tolerability, or for occasional use when full packs are not needed. Each tablet contains Diclofenac Sodium 100 mg in a sustained-release matrix that dissolves gradually over 12–16 hours, providing extended pain and inflammation relief from a single daily or twice-daily dose.
Sustained-Release Technology — Key Benefits
The SR matrix in A-Fenac SR 100 mg controls drug dissolution rate, maintaining therapeutic plasma diclofenac levels for 12–16 hours from each tablet. Compared to immediate-release A-Fenac 50 mg tablets taken three times daily, the SR formulation provides better overnight coverage (crucial for morning joint stiffness in arthritis), reduces dosing frequency (improving compliance), and may reduce peak plasma concentrations that contribute to GI irritation.
Indications
- Osteoarthritis — joint pain and morning stiffness
- Rheumatoid arthritis — continuous inflammation control
- Ankylosing spondylitis — first-line NSAID for axial SpA; SR formulation provides 24-hour coverage with twice daily dosing
- Acute back pain / sciatica — SR provides continuous coverage without daytime re-dosing
- Chronic musculoskeletal inflammatory conditions
Dosage
Standard adult dose: 100 mg once daily (evening) for maintenance, or 100 mg twice daily for severe inflammation.
Maximum: 200 mg/day total diclofenac from all formulations.
Elderly: 100 mg once daily maximum — reassess regularly.
Critical instruction: Swallow whole with water. Do not break, crush, or chew. Take after food. Co-prescribe PPI for regular users.
Important Warnings — Diabetes and NSAIDs
Diclofenac reduces renal prostaglandin synthesis, impairing renal blood flow autoregulation. In diabetic patients — especially those with nephropathy, on ACE inhibitors/ARBs, or dehydrated — this can precipitate acute kidney injury. Before prescribing in diabetic patients: check eGFR (avoid if <30), review concurrent medications, and ensure adequate hydration. Monitor BP — NSAIDs antagonise antihypertensives. For mild pain in diabetes, paracetamol is safer. Diclofenac carries the highest hepatotoxicity risk among common NSAIDs — monitor LFTs on long-term courses.
Contraindications
- NSAID hypersensitivity or aspirin-sensitive asthma
- Active peptic ulcer / GI bleeding
- Severe renal, hepatic, or cardiac impairment
- Third trimester of pregnancy
- Established cardiovascular disease (IHD, stroke, PAD)
Side Effects
GI: Dyspepsia, ulceration, GI bleeding — always co-prescribe PPI for regular use. Hepatic: Raised transaminases — monitor LFTs. Renal: Fluid retention, elevated creatinine — monitor eGFR. CV: Elevated BP, increased MI/stroke risk — avoid in established CV disease.
Frequently Asked Questions (FAQ)
Q: Why is this a 1-strip pack?
A: The 1-strip format suits short-term acute pain use, starting a new medication (to assess tolerability before buying a full box), travel packs, or situations where the patient needs only a few doses for a brief flare. For ongoing arthritis therapy, a full box provides better value.
Q: When should I take A-Fenac SR 100 mg for best effect?
A: For arthritis with morning stiffness, take in the evening so peak levels are reached overnight. This is when joint inflammation typically peaks (circadian inflammatory rhythm). For twice-daily dosing, take morning and evening with food.
Q: Can I take SR 100 mg at the same time as other diclofenac products?
A: No. Do not combine A-Fenac SR with other diclofenac formulations (A-Fenac 50 mg, A-Fenac injection) unless under specific medical direction. The maximum total dose is 200 mg/day from all sources combined.
Q: Is A-Fenac SR different from A-Fenac 50 mg tablets?
A: Yes. A-Fenac SR 100 mg releases diclofenac slowly over 12–16 hours, allowing once or twice daily dosing. A-Fenac 50 mg is immediate-release with 4–6 hour duration requiring 2–3 doses daily. Both contain diclofenac sodium — SR provides convenience and better overnight coverage for chronic use.
Medical Disclaimer
For educational purposes only. Not medical advice. Do not crush or chew SR tablets. Use under medical supervision with GI protection and regular monitoring. Consult your doctor if you have kidney disease, liver disease, heart disease, or diabetes before using diclofenac.
