Met 500 mg Tablet

Met 500 mg Tablet — Metformin Hydrochloride

Overview

Met 500 is manufactured by Opsonin Pharma Limited, a major Bangladeshi pharmaceutical company, providing a standard-strength metformin tablet for first-line management of type 2 diabetes.

Mechanism of Action

Metformin lowers blood glucose by reducing hepatic glucose production, decreasing intestinal glucose absorption, and improving insulin sensitivity in peripheral tissues, without stimulating pancreatic insulin secretion.

Indications

Met 500 is indicated for type 2 diabetes mellitus as first-line therapy alongside diet and exercise, used alone or in combination with other oral antidiabetic agents or insulin.

Dosage and Administration

The usual starting dose is 500 mg once or twice daily with meals, gradually titrated upward as tolerated, with typical maintenance doses of 1500–2000 mg/day in divided doses.

Contraindications

Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²), metabolic acidosis including diabetic ketoacidosis, and known hypersensitivity to metformin.

Side Effects

Common side effects include nausea, diarrhea, abdominal discomfort, and metallic taste, generally mild and improving with gradual dose titration. Long-term use may reduce vitamin B12 absorption.

Drug Interactions

Iodinated contrast media require temporary discontinuation of metformin. Alcohol intake should be limited. Disclose all current medications and supplements to your physician or pharmacist.

Special Precautions

Renal function should be assessed before starting therapy and monitored periodically, particularly in elderly patients.

Storage

Store below 30°C in a dry place, protected from light. Keep out of reach of children.

Frequently Asked Questions

Q1: Who manufactures Met 500?
Met 500 is manufactured by Opsonin Pharma Limited, a leading pharmaceutical company in Bangladesh.

Q2: Should Met 500 be taken with food?
Yes, taking it with or right after meals helps minimize gastrointestinal discomfort.

Q3: How long does it take for Met 500 to work?
Some glucose-lowering effect may be seen within days, but full benefit is usually assessed after several weeks of consistent use.

Q4: Can Met 500 be combined with other diabetes medications?
Yes, metformin is commonly combined with other oral antidiabetics or insulin as directed by your physician.

Medical Disclaimer: This information is provided for educational purposes only and does not replace professional medical advice. Always consult a registered physician or pharmacist before starting, stopping, or changing any medication. Dosage and suitability vary by individual health condition.