Metform ER 1000 mg

Metform ER 1000 mg Tablet — Metformin Hydrochloride (Extended Release)

Overview

Metform ER 1000 is the highest-strength extended-release metformin tablet from ACI Limited, intended for patients who need a strong once-daily metformin dose with the improved gastrointestinal tolerability of an extended-release formulation.

Mechanism of Action

Metformin reduces hepatic glucose production, decreases intestinal glucose absorption, and improves peripheral insulin sensitivity. The extended-release matrix releases the drug gradually, supporting once-daily dosing with steadier blood levels.

Indications

Metform ER 1000 is indicated for type 2 diabetes mellitus in patients requiring a higher extended-release metformin dose, typically prescribed after lower ER strengths have been well tolerated.

Dosage and Administration

Typically taken once daily with the evening meal; tablets must be swallowed whole and never crushed, split, or chewed. Confirm your exact dosing schedule and current price with your physician or pharmacist, as availability and packaging for this strength may vary.

Contraindications

Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²), metabolic acidosis including diabetic ketoacidosis, and known hypersensitivity to metformin.

Side Effects

Generally good gastrointestinal tolerability, though nausea, diarrhea, or abdominal discomfort can occur, particularly when stepping up to this highest strength. Long-term use may reduce vitamin B12 absorption.

Drug Interactions

Iodinated contrast media require temporary discontinuation of metformin. Alcohol intake should be limited. Disclose all current medications and supplements to your physician or pharmacist.

Special Precautions

Patients may occasionally notice the tablet matrix in stool; this is expected and does not indicate reduced effectiveness. Renal function should be reassessed before stepping up to this highest strength.

Storage

Store below 30°C in a dry place, protected from light. Keep out of reach of children.

Frequently Asked Questions

Q1: When would my doctor prescribe Metform ER 1000 instead of a lower ER strength?
It is typically prescribed when lower extended-release strengths do not provide adequate glycemic control and have been well tolerated.

Q2: Can I split a Metform ER 1000 tablet?
No, extended-release tablets must not be split, crushed, or chewed as this disrupts the controlled-release mechanism.

Q3: Should I confirm the price before ordering this strength?
Yes, please confirm the current price and pack size with the pharmacy, as this is a high-strength specialty listing.

Q4: Is Metform ER 1000 suitable for long-term use?
Yes, once an effective and well-tolerated dose is established, it is commonly used for long-term maintenance therapy.

Medical Disclaimer: This information is provided for educational purposes only and does not replace professional medical advice. Always consult a registered physician or pharmacist before starting, stopping, or changing any medication. Dosage and suitability vary by individual health condition.