Versia

Indication:
• Reversal of non-depolarizing neuromuscular blockade for surgical anesthetic procedures
• The prevention and treatment of post-operative distention and urinary retention after mechanical obstruction has been excluded
• Treatment of the systemic control of Myasthenia gravis when oral therapy is impractical

Dosage & Administration:
Adults: By intramuscular or subcutaneous injection:
Symptomatic control of myasthenia gravis: 1 ml of the 1:2000 solution (0.5 mg) intramuscularly or subcutaneously. Subsequent dose should be based on the individual patient's response.
Treatment of post-operative distention: 1 ml of the 1:2000 solution (0.5 mg) intramuscularly or subcutaneously or as required.
Prevention of post-operative distention and urinary retention: 1 ml of the 1:4000 solution (0.25 mg) intramuscularly or subcutaneously as soon as possible after operation; repeat every 4-6 hours for 2-3 days.
Treatment of urinary retention: 1 ml of the 1:2000 solution (0.5 mg) intra-muscularly or subcutaneously. If urination does not occur within an hour, the patient should be catheterized. After the patient has voided, or the bladder has been emptied, continue the 0.5 mg injection every 3 hrs, for at least 5 injections.
Reversal of Effects of Non-depolarizing Neuromuscular Blocking Agents; when Neostigmine is administered intravenously, it is recommended that Atropine Sulphate (0.6-1.2 mg) also be given intravenously using separate syringe. The usual dose is 0.5 to 2 mg is given by slow intravenous injection, repeated as required. On exceptional cases total dose should be exceed 5 mg.
Neonates: 50-250 micrograms every 4 hrs.
Children: 200-500 micrograms as recommended.