- Stock: Out Of Stock
- Brand: Acme Laboratories Limited
- Product ID: Metformin Hydrochloride
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Daomin XR 500 mg Tablet — Metformin Hydrochloride (Extended Release)
| Generic Name | Metformin Hydrochloride (Extended Release) |
|---|---|
| Strength | 500 mg |
| Dosage Form | Extended-Release Tablet |
| Manufacturer | The ACME Laboratories Ltd. |
| Therapeutic Class | Biguanide — Oral Antidiabetic (Extended Release) |
| Pack Size | 100 Tablets |
Overview
Daomin XR 500 mg is the extended-release metformin formulation from The ACME Laboratories Ltd., designed for once-daily dosing convenience and improved gastrointestinal tolerability for patients sensitive to immediate-release metformin.
Mechanism of Action
The extended-release matrix releases metformin gradually over several hours, providing smoother plasma concentrations and reducing the absorption spikes linked to gastrointestinal side effects, while retaining the same core glucose-lowering mechanism as standard metformin.
Indications
Daomin XR 500 mg is indicated for type 2 diabetes mellitus, particularly for patients with gastrointestinal sensitivity to immediate-release metformin or those who prefer once-daily dosing for better adherence.
Dosage and Administration
The typical starting dose is 500 mg once daily with the evening meal, increased in 500 mg increments at intervals of at least one week as needed, up to a maximum of 2000 mg once daily. Tablets must be swallowed whole and never crushed, split, or chewed.
Contraindications
Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²), metabolic acidosis including diabetic ketoacidosis, and known hypersensitivity to metformin.
Side Effects
Daomin XR generally causes fewer gastrointestinal side effects than immediate-release metformin, though nausea or diarrhea can still occur during dose titration. Long-term use may reduce vitamin B12 absorption. An inert tablet remnant occasionally seen in stool is a normal feature of extended-release formulations.
Drug Interactions
Iodinated contrast media require temporary discontinuation of metformin. Alcohol intake should be limited. Disclose all current medications and supplements to your physician or pharmacist.
Special Precautions
Do not switch between immediate-release and extended-release metformin without physician guidance. Renal function should be assessed before initiation and monitored periodically.
Storage
Store below 30°C in a dry place, protected from light. Keep out of reach of children.
Frequently Asked Questions
Q1: Why might my doctor switch me to Daomin XR from regular metformin?
Extended-release formulations often improve gastrointestinal tolerability and simplify dosing to once daily.
Q2: Can Daomin XR 500 be taken in the morning instead of evening?
It is generally recommended with the evening meal, but follow your physician's specific instructions for your regimen.
Q3: Is seeing a tablet remnant in stool with Daomin XR concerning?
No, this is a normal and harmless feature of extended-release tablet shells passing through the digestive tract.
Q4: How does Daomin XR 500 differ from Daomin XR 1000?
Both use the same extended-release technology; the 1000 mg strength delivers a higher per-tablet dose for patients with greater dosing needs.
Medical Disclaimer: This information is provided for educational purposes only and does not replace professional medical advice. Always consult a registered physician or pharmacist before starting, stopping, or changing any medication. Dosage and suitability vary by individual health condition.
