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HALOBET 10gm Oint.

HALOBET 10gm Oint.
HALOBET 10gm Oint.
Tk130.00
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Generic NameHalobetasol Propionate
Strength0.05%
Dosage FormOintment
ManufacturerSquare Pharmaceuticals PLC
Therapeutic ClassOther Topical corticosteroids
Pack Size20 gm tube

Overview

Halobet 0.05% Ointment contains Halobetasol Propionate, a super-high potency topical corticosteroid used for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Halobetasol Propionate exerts anti-inflammatory, antipruritic, and vasoconstrictive actions via induction of phospholipase A2 inhibitory proteins (lipocortins), which suppress the biosynthesis of prostaglandins and leukotrienes by inhibiting the release of arachidonic acid from membrane phospholipids. The ointment formulation provides an occlusive base that may enhance skin penetration compared to the cream. Due to its super-high potency, treatment is limited to two consecutive weeks and must not exceed 50 gm per week to avoid HPA axis suppression.

Dosage and Administration

Apply a thin layer of Halobet 0.05% Ointment to the affected skin once or twice daily as directed by the physician, and rub in gently and completely. Treatment should be limited to two consecutive weeks. Total usage must not exceed 50 gm per week. Discontinue once the condition is controlled. If no improvement after 2 weeks, reassess the diagnosis. Do not use with occlusive dressings. Not for use on the face, groin, or axillae.

Interaction

No significant drug–drug interactions are anticipated with topical Halobetasol Propionate under normal conditions of use. Concurrent use of other topical corticosteroids on the same area or systemic corticosteroids may increase the risk of systemic adverse effects. Consult a physician before using alongside other immunosuppressive treatments.

Contraindications

Halobet Ointment is contraindicated in patients with known hypersensitivity to Halobetasol Propionate or any component of the formulation. It should not be used on the face, groin, or axillae, and is not intended for ophthalmic, oral, or intravaginal use. Use in children under 12 years is not recommended.

Side Effects

Infrequently reported adverse effects include burning, itching, dryness, folliculitis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin atrophy, secondary infections, striae, and miliaria. Systemic effects — such as HPA axis suppression, Cushing's syndrome, hyperglycaemia, and glucosuria — may occur with excessive, prolonged, or large-area application.

Pregnancy and Lactation

Topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. It is unknown whether topical Halobetasol Propionate produces sufficient systemic absorption to yield detectable levels in breast milk; caution is advised in breastfeeding women.

Precautions and Warnings

Patients using large amounts, applying to large surface areas, or using under occlusive dressings should be periodically evaluated for HPA axis suppression via urinary free cortisol and ACTH stimulation tests. If suppression is detected, withdraw the drug, reduce application frequency, or switch to a lower-potency steroid. Paediatric patients are at greater risk of HPA axis suppression than adults; use in children under 12 is not recommended.

Storage Conditions

Store below 30°C. Keep all medicines out of reach of children.

Frequently Asked Questions

Q: What is the difference between Halobet Cream and Halobet Ointment?
Both Halobet Cream and Halobet Ointment contain the same active ingredient — Halobetasol Propionate 0.05% — and are indicated for the same corticosteroid-responsive dermatoses. The ointment formulation has an oil-based, occlusive base that is better suited for dry, thick, or lichenified skin, while the cream is better for moist or weeping conditions and is more cosmetically acceptable for daytime use.

Q: How long is it safe to use Halobet Ointment?
Treatment with Halobet 0.05% Ointment should not exceed two consecutive weeks, and the total amount used should not exceed 50 gm per week. Prolonged use risks HPA axis suppression and other systemic corticosteroid effects. Once the skin condition is controlled, the treatment should be discontinued promptly.

Disclaimer: This information is provided for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a registered physician before starting, modifying, or discontinuing any medication.

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