Zinc-10mg

Oral-Z Syrup

Zinc Sulfate tablet and syrup is indicated for the prophylaxis and treatment of Zinc deficiency states:

Diarrhoea

Severe growth retardation

Recurrent respiratory tract infections

Ichemia

Dental disturbances

Alopecia

Loss of Appetite

Night blindness

Deformed bone formation

Impaired immunological response

Acrodermatitis enteropathica

Parakeratotic skin lesion

Effective & delayed wound healing

Infertility

Zinc Sulfate dispersible tablet is indicated for the treatment of diarrhoea, especially for the children fr om 2 months to 5 years of age in connection with Oral Rehydration Salts (ORS)

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Therapeutic Class

Specific mineral preparations

Description

Zinc Sulfate Monohydrate is a source of Zinc which is an essential trace element and involved in a number of body enzyme systems. Symptoms of less severe Zinc deficiency include distorted or absent perceptions of taste and smell and poor wound healing. Severe Zinc deficiency causes skin lesion, alopecia, diarrhoea, increased susceptibility to infections and failure to thrive in children.

Pharmacology

Zinc is an essential trace mineral, which means that it must be obtained from the diet since the body cannot make enough. Next to iron, zinc is the most abundant trace mineral in the body. Stored primarily in muscle, zinc is also found in high concentrations in red and white blood cells, the retina of the eye, bones, skin, kidneys, liver, and pancreas. Some of the symptoms of zinc deficiency include loss of appetite, poor growth, weight loss, impaired taste or smell, poor wound healing, skin abnormalities (such as acne, atopic dermatitis and psoriasis), hair loss, night blindness, hypogonadism and delayed sexual maturation, white spots on the fingernails and feelings of depression.

Dosage

Children under 10 kg: 1 teaspoonful or ½ tablet (If the children can swallow) 2 times daily or as directed by the physician.

Children (10-30 kg): 1 tablet or 2 teaspoonfuls 1-3 times daily or as directed by the physician.

Adults & Children over 30 kg: 2 tablets or 4teaspoonfuls1-3 times daily or as directed by the physician.

Zinc supplements are most effective if they are taken at least 1 hour before or 2 hour after a meal. However, if Zinc supplements cause stomach upset, they may be taken with a meal.

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Administration

For dispersible tablet-

Place the tablet in a teaspoon

Add adequate amount of water

Let the tablet dissolve completely

Give the entire spoonful solution

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Interaction

Zinc may inhibit the absorption of concurrently administered tetracyclines, when both are being given an interval of at least 3 hours.

Contraindications

It is contraindicated in patients with hypersensitivity to Zinc.

Side Effects

In case of zinc mild side effects such as gastric ulcer, nausea, vomiting, metallic taste, headache, drowsiness have been observed.

Pregnancy & Lactation

Pregnant women and nursing mothers should avoid zinc doses higher than RDA amounts.

Precautions

Concurrent administration of Zinc salt with penicillamine might diminish the effect of Penicillamine. The absorption of Zinc, although poor, may be decreased by various compounds including some foods. Chelation may occur with tetracyclines.

Overdose Effects

Zinc sulphate is corrosive in overdose. Symptoms are corrosion and inflammation of the mucous membrane of the mouth and stomach; ulceration of the stomach followed by perforation may occur. Gastric lavage and emesis should be avoided. Demulcents such as milk should be given. Chelating agents such as sodium edetate may be useful.

Storage Conditions

Store in a cool place. The syrup should be protected from light.