Carbizol 5 mg Tablet

Overview

Carbizol 5 mg Tablet contains Carbimazole, manufactured by Square Pharmaceuticals PLC. It is an antithyroid agent used in the treatment of hyperthyroidism, including Graves' disease and toxic nodular goitre. It acts by inhibiting the synthesis of thyroid hormones.

Dosage and Administration

Initial dose: usually 20-60 mg daily in divided doses, depending on severity, gradually reduced to a maintenance dose of 5-15 mg daily once euthyroidism is achieved, as prescribed by the physician. Treatment duration is typically 12-18 months.

Interaction

May potentiate the effect of anticoagulants (warfarin); monitor INR closely. Thyroid function changes may alter dosage requirements for other medications metabolised differently in hyperthyroid vs. euthyroid states.

Contraindications

Contraindicated in patients with known hypersensitivity to carbimazole, and in those with severe blood dyscrasias.

Side Effects

Agranulocytosis (rare but serious — patients must seek immediate medical attention for fever or sore throat), rash, pruritus, nausea, headache, and arthralgia. Hypothyroidism may occur with excessive doses.

Pregnancy and Lactation

Can be used during pregnancy at the lowest effective dose under close medical supervision, as untreated hyperthyroidism carries greater risk than treatment. Breastfeeding is possible with low maternal doses under physician guidance.

Precautions and Warnings

Patients must be advised to seek immediate medical attention if they develop fever, sore throat, or mouth ulcers, as these may indicate agranulocytosis — a rare but life-threatening complication. Regular monitoring of thyroid function and blood counts is essential during treatment.

Storage Conditions

Store below 30°C, in a dry place, protected from light and moisture. Keep out of the reach of children.

Frequently Asked Questions

What should I do if I develop a fever or sore throat while taking Carbizol?
Stop the medication and seek immediate medical attention, as these symptoms may indicate agranulocytosis — a rare but serious reduction in white blood cells.

How long is Carbizol taken for?
Treatment is typically continued for 12-18 months; the physician will monitor thyroid function throughout and adjust the dose accordingly.

This content is for informational purposes only and does not substitute professional medical advice. Please consult a registered physician before taking any medication.